BR0010982A - Novas oxazolidinonas bicìclicas como agentes antibacterianos - Google Patents

Novas oxazolidinonas bicìclicas como agentes antibacterianos

Info

Publication number
BR0010982A
BR0010982A BR0010982-7A BR0010982A BR0010982A BR 0010982 A BR0010982 A BR 0010982A BR 0010982 A BR0010982 A BR 0010982A BR 0010982 A BR0010982 A BR 0010982A
Authority
BR
Brazil
Prior art keywords
antibacterial agents
oxazolidinones
new bicyclic
new
bicyclic oxazolidinones
Prior art date
Application number
BR0010982-7A
Other languages
English (en)
Inventor
Michael J Genin
Jackson B Hester Jr
Michael R Barbachyn
Paul D Johnson
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of BR0010982A publication Critical patent/BR0010982A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42—Oxazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Ophthalmology & Optometry (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

"NOVAS OXAZOLIDINONAS BICìCLICAS COMO AGENTES ANTIBACTERIANOS". A presente invenção provê compostos da fórmula I úteis como agentes antimicrobianos, onde W, X, Y, R^ 1^, R^ 2^ e n são como definidos na mesma.
BR0010982-7A 1999-05-27 2000-05-17 Novas oxazolidinonas bicìclicas como agentes antibacterianos BR0010982A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US13625099P 1999-05-27 1999-05-27
PCT/US2000/008224 WO2000073301A1 (en) 1999-05-27 2000-05-17 Bicyclic oxazolidinones as antibacterial agent

Publications (1)

Publication Number Publication Date
BR0010982A true BR0010982A (pt) 2002-03-05

Family

ID=22472021

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0010982-7A BR0010982A (pt) 1999-05-27 2000-05-17 Novas oxazolidinonas bicìclicas como agentes antibacterianos

Country Status (20)

Country Link
US (2) US6387896B1 (pt)
EP (1) EP1181288B1 (pt)
JP (1) JP2003501351A (pt)
KR (1) KR20020012245A (pt)
CN (1) CN1142162C (pt)
AR (1) AR024118A1 (pt)
AT (1) ATE246189T1 (pt)
AU (1) AU767380B2 (pt)
BR (1) BR0010982A (pt)
CA (1) CA2372233A1 (pt)
DE (1) DE60004207T2 (pt)
DK (1) DK1181288T3 (pt)
ES (1) ES2203473T3 (pt)
HK (1) HK1046680B (pt)
MX (1) MXPA01012167A (pt)
NZ (1) NZ515754A (pt)
PE (1) PE20010166A1 (pt)
PT (1) PT1181288E (pt)
WO (1) WO2000073301A1 (pt)
ZA (1) ZA200109384B (pt)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ515754A (en) * 1999-05-27 2003-10-31 Upjohn Co Bicyclic oxazolidinone compounds, pharmaceuticals thereof and their use as antibacterial agents
CA2395648A1 (en) * 2000-02-10 2001-08-16 Pharmacia & Upjohn Company Oxazolidinone thioamides with piperazine amide substituents
US6642238B2 (en) 2000-02-10 2003-11-04 Pharmacia And Upjohn Company Oxazolidinone thioamides with piperazine amide substituents
CN1208058C (zh) * 2000-03-22 2005-06-29 法玛西雅厄普约翰美国公司 噁唑烷酮片剂的配方
US6514529B2 (en) 2000-03-22 2003-02-04 Pharmacia & Upjohn Company Oxazolidinone tablet formulation
PE20020689A1 (es) 2000-11-17 2002-08-03 Upjohn Co Oxazolidinonas con un heterociclo de 6 o 7 miembros unidos con enlace anular al benceno
US7141588B2 (en) 2002-02-25 2006-11-28 Pfizer, Inc. N-aryl-2-oxazolidinone-5-carboxamides and their derivatives
AR038536A1 (es) 2002-02-25 2005-01-19 Upjohn Co N-aril-2-oxazolidinona-5- carboxamidas y sus derivados
US7304050B2 (en) 2003-09-16 2007-12-04 Pfizer Inc. Antibacterial agents
EP1781642A1 (en) * 2004-08-06 2007-05-09 Pharmacia & Upjohn Company LLC Oxazolidinones containing oxindoles as antibacterial agents
AU2006231918A1 (en) * 2005-04-06 2006-10-12 Pharmacia & Upjohn Company Llc An oxindole oxazolidinone as antibacterial agent
AU2006231919A1 (en) 2005-04-06 2006-10-12 Pharmacia & Upjohn Company Llc 7-fluoro-1,3-dihydro-indol-2-one oxazolidinones as antibacterial agents
TW201018662A (en) * 2005-12-12 2010-05-16 Astrazeneca Ab Alkylsulphonamide quinolines
AU2009318783A1 (en) 2008-11-20 2011-06-23 Panacea Biotec Ltd. Novel antimicrobials
CN102803224A (zh) 2009-06-26 2012-11-28 万能药生物有限公司 新的氮杂双环己烷类化合物

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES533097A0 (es) 1983-06-07 1985-08-01 Du Pont Un procedimiento para la preparacion de nuevos derivados del amino-metil-oxooxazolidinil-benzeno.
US5036093A (en) 1987-10-09 1991-07-30 Du Pont Merck Pharmaceutical Aminomethyl oxooxazolidinyl azacycloalkylbenzene derivatives useful as antibacterial agents
US4965268A (en) 1987-10-09 1990-10-23 E. I. Du Pont De Nemours And Company Aminomethyl oxooxazolidinyl cycloalkylbenzene derivatives useful as antibacterial agents
US5039690A (en) 1987-10-09 1991-08-13 Du Pont Merck Pharmaceutical Company Aminomethyl oxooxazolidinyl oxa or thia cycloalkylbenzene derivatives useful as antibacterial agents
US4801600A (en) * 1987-10-09 1989-01-31 E. I. Du Pont De Nemours And Company Aminomethyl oxooxazolidinyl cycloalkylbenzene derivatives useful as antibacterial agents
US5032605A (en) 1987-10-09 1991-07-16 Du Pont Merck Pharmaceutical Company Aminomethyl oxooxazolidinyl oxa or thia cycloalkylbenzene derivatives useful as antibacterial agents
US5036092A (en) 1987-10-09 1991-07-30 Du Pont Merck Pharmaceutical Aminomethyl oxooxazolidinyl azacycloalkylbenzene derivatives useful as antibacterial agents
US5164510A (en) 1988-09-15 1992-11-17 The Upjohn Company 5'Indolinyl-5β-amidomethyloxazolidin-2-ones
WO1990002744A1 (en) * 1988-09-15 1990-03-22 The Upjohn Company In position 3 substituted-5-beta-amidomethyl-oxazolidin-2-ones
DE4425609A1 (de) 1994-07-20 1996-01-25 Bayer Ag Benzofuranyl- und Benzothienyloxazolidinone
ZA968661B (en) 1995-11-17 1998-04-14 Upjohn Co Oxazolidinone antibacterial agent with tricyclic substituents.
DE19604223A1 (de) 1996-02-06 1997-08-07 Bayer Ag Neue substituierte Oxazolidinone
DE19802239A1 (de) 1998-01-22 1999-07-29 Bayer Ag Neue mit Bicyclen substituierte Oxazolidinone
NZ515754A (en) * 1999-05-27 2003-10-31 Upjohn Co Bicyclic oxazolidinone compounds, pharmaceuticals thereof and their use as antibacterial agents

Also Published As

Publication number Publication date
HK1046680B (zh) 2004-12-31
US20020143009A1 (en) 2002-10-03
PT1181288E (pt) 2003-12-31
EP1181288B1 (en) 2003-07-30
CN1353709A (zh) 2002-06-12
US6387896B1 (en) 2002-05-14
WO2000073301A1 (en) 2000-12-07
CA2372233A1 (en) 2000-12-07
NZ515754A (en) 2003-10-31
AU4797500A (en) 2000-12-18
EP1181288A1 (en) 2002-02-27
DK1181288T3 (da) 2003-11-17
PE20010166A1 (es) 2001-02-03
JP2003501351A (ja) 2003-01-14
AU767380B2 (en) 2003-11-06
KR20020012245A (ko) 2002-02-15
AR024118A1 (es) 2002-09-04
DE60004207D1 (de) 2003-09-04
MXPA01012167A (es) 2002-06-21
HK1046680A1 (en) 2003-01-24
ZA200109384B (en) 2003-02-14
ATE246189T1 (de) 2003-08-15
DE60004207T2 (de) 2004-06-03
CN1142162C (zh) 2004-03-17
ES2203473T3 (es) 2004-04-16

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 7O, 8O E 9O ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 DA RPI 2008 DE 30/06/2009.