BG61400B1 - Means for detecting residual quantities of bactericidal compounds in liquids - Google Patents

Means for detecting residual quantities of bactericidal compounds in liquids Download PDF

Info

Publication number: BG61400B1
Authority: BG; Bulgaria
Prior art keywords: agent; test organism; agar medium; test; sensitivity
Prior art date: 1993-02-11

Application number

BG98900A

Other languages

Bulgarian (bg)

English (en)

Other versions

BG98900A (bg

Inventor

Rijn Ferdinand T Van

Robert Beukers

Johannes H Kerkhof

Original Assignee

Gist Brocades Bv

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1993-02-11

Filing date

1994-07-11

Publication date

1997-07-31

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8213637&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BG61400(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1994-07-11 Application filed by Gist Brocades Bv filed Critical Gist Brocades Bv

1995-09-29 Publication of BG98900A publication Critical patent/BG98900A/bg

1997-07-31 Publication of BG61400B1 publication Critical patent/BG61400B1/bg

Links

230000000844 anti-bacterial effect Effects 0.000 title claims abstract description 20
150000001875 compounds Chemical class 0.000 title claims abstract description 20
239000007788 liquid Substances 0.000 title abstract description 7
238000012360 testing method Methods 0.000 claims abstract description 70
229920001817 Agar Polymers 0.000 claims abstract description 34
239000008272 agar Substances 0.000 claims abstract description 34
239000002609 medium Substances 0.000 claims description 37
239000003795 chemical substances by application Substances 0.000 claims description 21
238000000034 method Methods 0.000 claims description 21
239000002824 redox indicator Substances 0.000 claims description 18
235000015097 nutrients Nutrition 0.000 claims description 11
230000035945 sensitivity Effects 0.000 claims description 10
235000013305 food Nutrition 0.000 claims description 8
241000193385 Geobacillus stearothermophilus Species 0.000 claims description 7
239000000126 substance Substances 0.000 claims description 7
241000193830 Bacillus <bacterium> Species 0.000 claims description 5
241000194017 Streptococcus Species 0.000 claims description 4
241000194020 Streptococcus thermophilus Species 0.000 claims description 4
IEDVJHCEMCRBQM-UHFFFAOYSA-N trimethoprim Chemical group COC1=C(OC)C(OC)=CC(CC=2C(=NC(N)=NC=2)N)=C1 IEDVJHCEMCRBQM-UHFFFAOYSA-N 0.000 claims description 4
229960001082 trimethoprim Drugs 0.000 claims description 4
230000003432 anti-folate effect Effects 0.000 claims description 3
229940127074 antifolate Drugs 0.000 claims description 3
239000004052 folic acid antagonist Substances 0.000 claims description 3
238000001228 spectrum Methods 0.000 claims description 3
WSWJIZXMAUYHOE-UHFFFAOYSA-N tetroxoprim Chemical compound C1=C(OC)C(OCCOC)=C(OC)C=C1CC1=CN=C(N)N=C1N WSWJIZXMAUYHOE-UHFFFAOYSA-N 0.000 claims description 3
229960004809 tetroxoprim Drugs 0.000 claims description 3
KEEYRKYKLYARHO-UHFFFAOYSA-N 5-[(4,5-dimethoxy-2-methylphenyl)methyl]pyrimidine-2,4-diamine Chemical compound C1=C(OC)C(OC)=CC(C)=C1CC1=CN=C(N)N=C1N KEEYRKYKLYARHO-UHFFFAOYSA-N 0.000 claims description 2
239000003899 bactericide agent Substances 0.000 claims description 2
239000001963 growth medium Substances 0.000 claims description 2
229960003068 ormetoprim Drugs 0.000 claims description 2
230000001235 sensitizing effect Effects 0.000 claims 2
239000008267 milk Substances 0.000 abstract description 7
210000004080 milk Anatomy 0.000 abstract description 7
235000013336 milk Nutrition 0.000 abstract description 7
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract description 6
235000011389 fruit/vegetable juice Nutrition 0.000 abstract description 3
235000013372 meat Nutrition 0.000 abstract description 3
239000000203 mixture Substances 0.000 abstract description 3
210000002966 serum Anatomy 0.000 abstract description 3
210000002700 urine Anatomy 0.000 abstract description 3
238000009472 formulation Methods 0.000 abstract 1
239000000243 solution Substances 0.000 description 8
229950003937 tolonium Drugs 0.000 description 7
HNONEKILPDHFOL-UHFFFAOYSA-M tolonium chloride Chemical compound [Cl-].C1=C(C)C(N)=CC2=[S+]C3=CC(N(C)C)=CC=C3N=C21 HNONEKILPDHFOL-UHFFFAOYSA-M 0.000 description 7
JGSARLDLIJGVTE-MBNYWOFBSA-N Penicillin G Chemical compound N([C@H]1[C@H]2SC([C@@H](N2C1=O)C(O)=O)(C)C)C(=O)CC1=CC=CC=C1 JGSARLDLIJGVTE-MBNYWOFBSA-N 0.000 description 4
229940088710 antibiotic agent Drugs 0.000 description 4
238000002360 preparation method Methods 0.000 description 4
GMMAPXRGRVJYJY-UHFFFAOYSA-J tetrasodium 4-acetamido-5-hydroxy-6-[[7-sulfonato-4-[(4-sulfonatophenyl)diazenyl]naphthalen-1-yl]diazenyl]naphthalene-1,7-disulfonate Chemical compound [Na+].[Na+].[Na+].[Na+].OC1=C2C(NC(=O)C)=CC=C(S([O-])(=O)=O)C2=CC(S([O-])(=O)=O)=C1N=NC(C1=CC(=CC=C11)S([O-])(=O)=O)=CC=C1N=NC1=CC=C(S([O-])(=O)=O)C=C1 GMMAPXRGRVJYJY-UHFFFAOYSA-J 0.000 description 4
QIRDPEPUXNCOLD-UHFFFAOYSA-N [9-(diethylamino)benzo[a]phenoxazin-5-ylidene]azanium;sulfate Chemical compound [O-]S([O-])(=O)=O.C1=CC=C2C3=NC4=CC=C(N(CC)CC)C=C4OC3=CC(=[NH2+])C2=C1.C1=CC=C2C3=NC4=CC=C(N(CC)CC)C=C4OC3=CC(=[NH2+])C2=C1 QIRDPEPUXNCOLD-UHFFFAOYSA-N 0.000 description 3
239000003242 anti bacterial agent Substances 0.000 description 3
239000011248 coating agent Substances 0.000 description 3
238000000576 coating method Methods 0.000 description 3
238000001514 detection method Methods 0.000 description 3
239000012530 fluid Substances 0.000 description 3
CXKWCBBOMKCUKX-UHFFFAOYSA-M methylene blue Chemical compound [Cl-].C1=CC(N(C)C)=CC2=[S+]C3=CC(N(C)C)=CC=C3N=C21 CXKWCBBOMKCUKX-UHFFFAOYSA-M 0.000 description 3
229960000907 methylthioninium chloride Drugs 0.000 description 3
244000005700 microbiome Species 0.000 description 3
241000894007 species Species 0.000 description 3
239000000725 suspension Substances 0.000 description 3
PVPBBTJXIKFICP-UHFFFAOYSA-N (7-aminophenothiazin-3-ylidene)azanium;chloride Chemical compound [Cl-].C1=CC(=[NH2+])C=C2SC3=CC(N)=CC=C3N=C21 PVPBBTJXIKFICP-UHFFFAOYSA-N 0.000 description 2
SGHZXLIDFTYFHQ-UHFFFAOYSA-L Brilliant Blue Chemical compound [Na+].[Na+].C=1C=C(C(=C2C=CC(C=C2)=[N+](CC)CC=2C=C(C=CC=2)S([O-])(=O)=O)C=2C(=CC=CC=2)S([O-])(=O)=O)C=CC=1N(CC)CC1=CC=CC(S([O-])(=O)=O)=C1 SGHZXLIDFTYFHQ-UHFFFAOYSA-L 0.000 description 2
108091006149 Electron carriers Proteins 0.000 description 2
LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 2
KRHYYFGTRYWZRS-UHFFFAOYSA-N Fluorane Chemical compound F KRHYYFGTRYWZRS-UHFFFAOYSA-N 0.000 description 2
XXACTDWGHQXLGW-UHFFFAOYSA-M Janus Green B chloride Chemical compound [Cl-].C12=CC(N(CC)CC)=CC=C2N=C2C=CC(\N=N\C=3C=CC(=CC=3)N(C)C)=CC2=[N+]1C1=CC=CC=C1 XXACTDWGHQXLGW-UHFFFAOYSA-M 0.000 description 2
229930182555 Penicillin Natural products 0.000 description 2
FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 2
230000002378 acidificating effect Effects 0.000 description 2
OIRDTQYFTABQOQ-KQYNXXCUSA-N adenosine Chemical compound C1=NC=2C(N)=NC=NC=2N1[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O OIRDTQYFTABQOQ-KQYNXXCUSA-N 0.000 description 2
230000003115 biocidal effect Effects 0.000 description 2
230000015572 biosynthetic process Effects 0.000 description 2
239000007853 buffer solution Substances 0.000 description 2
239000003054 catalyst Substances 0.000 description 2
IQFVPQOLBLOTPF-HKXUKFGYSA-L congo red Chemical compound [Na+].[Na+].C1=CC=CC2=C(N)C(/N=N/C3=CC=C(C=C3)C3=CC=C(C=C3)/N=N/C3=C(C4=CC=CC=C4C(=C3)S([O-])(=O)=O)N)=CC(S([O-])(=O)=O)=C21 IQFVPQOLBLOTPF-HKXUKFGYSA-L 0.000 description 2
229910003460 diamond Inorganic materials 0.000 description 2
239000010432 diamond Substances 0.000 description 2
239000012153 distilled water Substances 0.000 description 2
238000002474 experimental method Methods 0.000 description 2
KHLVKKOJDHCJMG-QDBORUFSSA-L indigo carmine Chemical compound [Na+].[Na+].N/1C2=CC=C(S([O-])(=O)=O)C=C2C(=O)C\1=C1/NC2=CC=C(S(=O)(=O)[O-])C=C2C1=O KHLVKKOJDHCJMG-QDBORUFSSA-L 0.000 description 2
229960003988 indigo carmine Drugs 0.000 description 2
235000012738 indigotine Nutrition 0.000 description 2
239000004179 indigotine Substances 0.000 description 2
239000002207 metabolite Substances 0.000 description 2
229940056360 penicillin g Drugs 0.000 description 2
150000002960 penicillins Chemical class 0.000 description 2
OARRHUQTFTUEOS-UHFFFAOYSA-N safranin Chemical compound [Cl-].C=12C=C(N)C(C)=CC2=NC2=CC(C)=C(N)C=C2[N+]=1C1=CC=CC=C1 OARRHUQTFTUEOS-UHFFFAOYSA-N 0.000 description 2
229960002135 sulfadimidine Drugs 0.000 description 2
ASWVTGNCAZCNNR-UHFFFAOYSA-N sulfamethazine Chemical compound CC1=CC(C)=NC(NS(=O)(=O)C=2C=CC(N)=CC=2)=N1 ASWVTGNCAZCNNR-UHFFFAOYSA-N 0.000 description 2
239000002126 C01EB10 - Adenosine Substances 0.000 description 1
WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 1
MUBZPKHOEPUJKR-UHFFFAOYSA-N Oxalic acid Chemical class OC(=O)C(O)=O MUBZPKHOEPUJKR-UHFFFAOYSA-N 0.000 description 1
GSEJCLTVZPLZKY-UHFFFAOYSA-N Triethanolamine Chemical compound OCCN(CCO)CCO GSEJCLTVZPLZKY-UHFFFAOYSA-N 0.000 description 1
DGEZNRSVGBDHLK-UHFFFAOYSA-N [1,10]phenanthroline Chemical compound C1=CN=C2C3=NC=CC=C3C=CC2=C1 DGEZNRSVGBDHLK-UHFFFAOYSA-N 0.000 description 1
239000002696 acid base indicator Substances 0.000 description 1
CQPFMGBJSMSXLP-UHFFFAOYSA-M acid orange 7 Chemical compound [Na+].OC1=CC=C2C=CC=CC2=C1N=NC1=CC=C(S([O-])(=O)=O)C=C1 CQPFMGBJSMSXLP-UHFFFAOYSA-M 0.000 description 1
229960005305 adenosine Drugs 0.000 description 1
XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 description 1
229910052782 aluminium Inorganic materials 0.000 description 1
KFZNPGQYVZZSNV-UHFFFAOYSA-M azure B Chemical compound [Cl-].C1=CC(N(C)C)=CC2=[S+]C3=CC(NC)=CC=C3N=C21 KFZNPGQYVZZSNV-UHFFFAOYSA-M 0.000 description 1
239000013060 biological fluid Substances 0.000 description 1
238000009395 breeding Methods 0.000 description 1
230000001488 breeding effect Effects 0.000 description 1
239000000872 buffer Substances 0.000 description 1
230000001332 colony forming effect Effects 0.000 description 1
230000003247 decreasing effect Effects 0.000 description 1
239000008121 dextrose Substances 0.000 description 1
VSSMQLIMSVAUDK-UHFFFAOYSA-L disodium;5-[(4-ethoxyphenyl)diazenyl]-2-[4-[(4-ethoxyphenyl)diazenyl]-2-sulfonatophenyl]sulfanylbenzenesulfonate Chemical compound [Na+].[Na+].C1=CC(OCC)=CC=C1N=NC(C=C1S([O-])(=O)=O)=CC=C1SC1=CC=C(N=NC=2C=CC(OCC)=CC=2)C=C1S([O-])(=O)=O VSSMQLIMSVAUDK-UHFFFAOYSA-L 0.000 description 1
BMYUQZABARGLAD-UHFFFAOYSA-L disodium;8-(4-methylanilino)-5-[[4-[(3-sulfonatophenyl)diazenyl]naphthalen-1-yl]diazenyl]naphthalene-1-sulfonate Chemical compound [Na+].[Na+].C1=CC(C)=CC=C1NC(C1=C(C=CC=C11)S([O-])(=O)=O)=CC=C1N=NC(C1=CC=CC=C11)=CC=C1N=NC1=CC=CC(S([O-])(=O)=O)=C1 BMYUQZABARGLAD-UHFFFAOYSA-L 0.000 description 1
239000000975 dye Substances 0.000 description 1
235000019441 ethanol Nutrition 0.000 description 1
239000011888 foil Substances 0.000 description 1
108010025181 halocyanin Proteins 0.000 description 1
230000005764 inhibitory process Effects 0.000 description 1
239000000463 material Substances 0.000 description 1
238000002844 melting Methods 0.000 description 1
230000008018 melting Effects 0.000 description 1
230000000813 microbial effect Effects 0.000 description 1
239000002777 nucleoside Substances 0.000 description 1
125000003835 nucleoside group Chemical group 0.000 description 1
238000012545 processing Methods 0.000 description 1
238000012797 qualification Methods 0.000 description 1
239000011780 sodium chloride Substances 0.000 description 1
239000008174 sterile solution Substances 0.000 description 1
125000000020 sulfo group Chemical group O=S(=O)([*])O[H] 0.000 description 1
150000003871 sulfonates Chemical class 0.000 description 1
150000003464 sulfur compounds Chemical class 0.000 description 1
150000003467 sulfuric acid derivatives Chemical class 0.000 description 1
238000010998 test method Methods 0.000 description 1

Classifications

- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/483—Physical analysis of biological material
- G01N33/487—Physical analysis of biological material of liquid biological material
- G01N33/493—Physical analysis of biological material of liquid biological material urine
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
- C12Q1/18—Testing for antimicrobial activity of a material
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/02—Food
- G01N33/04—Dairy products
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/02—Food
- G01N33/12—Meat; Fish
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/822—Microorganisms using bacteria or actinomycetales
- Y10S435/832—Bacillus

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Physics & Mathematics (AREA)
Food Science & Technology (AREA)
Biochemistry (AREA)
General Health & Medical Sciences (AREA)
Analytical Chemistry (AREA)
Organic Chemistry (AREA)
Immunology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Biomedical Technology (AREA)
Pathology (AREA)
Wood Science & Technology (AREA)
Zoology (AREA)
General Physics & Mathematics (AREA)
Medicinal Chemistry (AREA)
Biophysics (AREA)
Molecular Biology (AREA)
Urology & Nephrology (AREA)
Bioinformatics & Cheminformatics (AREA)
General Engineering & Computer Science (AREA)
Microbiology (AREA)
Biotechnology (AREA)
Toxicology (AREA)
Genetics & Genomics (AREA)
Hematology (AREA)
Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Investigating Or Analysing Biological Materials (AREA)
Geophysics And Detection Of Objects (AREA)
Automatic Analysis And Handling Materials Therefor (AREA)
Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
Agricultural Chemicals And Associated Chemicals (AREA)

BG98900A 1993-02-11 1994-07-11 Means for detecting residual quantities of bactericidal compounds in liquids BG61400B1 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP93200387		1993-02-11
PCT/EP1994/000359 WO1994018343A1 (en)	1993-02-11	1994-02-09	Unit for the detection of residues of antibacterial compounds in liquids

Publications (2)

Publication Number	Publication Date
BG98900A BG98900A (bg)	1995-09-29
BG61400B1 true BG61400B1 (en)	1997-07-31

Family

ID=8213637

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BG98900A BG61400B1 (en)	1993-02-11	1994-07-11	Means for detecting residual quantities of bactericidal compounds in liquids

Country Status (23)

Country	Link
US (1)	US5494805A (ko)
EP (1)	EP0611001B1 (ko)
KR (1)	KR950700031A (ko)
AT (1)	ATE217910T1 (ko)
AU (1)	AU668023B2 (ko)
BG (1)	BG61400B1 (ko)
BR (1)	BR9403895A (ko)
CA (1)	CA2117890A1 (ko)
CZ (1)	CZ251094A3 (ko)
DE (1)	DE69430645T2 (ko)
DK (1)	DK0611001T3 (ko)
ES (1)	ES2176220T3 (ko)
FI (1)	FI944709A (ko)
HU (1)	HUT67913A (ko)
IL (1)	IL108616A (ko)
NZ (1)	NZ261583A (ko)
PL (1)	PL179275B1 (ko)
PT (1)	PT611001E (ko)
RO (1)	RO114686B1 (ko)
RU (1)	RU94045954A (ko)
UY (1)	UY23732A1 (ko)
WO (1)	WO1994018343A1 (ko)
ZA (1)	ZA94959B (ko)

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DE4432771A1 (de) *	1994-09-14	1996-03-21	Landesvereinigung Der Bayerisc	Testmedium für einen mikrobiologischen Hemmstofftest und Verfahren zu seiner Durchführung
BR9603963A (pt) *	1995-02-01	1997-10-07	Gist Brocades Bv	Processo para a detecção de um ou mais compostos antibacterianos em uma amostra líquida e unidade de teste para a realização do processo
FR2732693B1 (fr) *	1995-04-06	1997-05-09	Bio Veto Tests Bvt	Temoin de revelation de contaminants et procede d'application a la realisation d'un antibiogramme directement effectue sur prelevement
ES2256048T5 (es) †	1999-10-04	2009-12-02	Dsm Ip Assets B.V.	Prueba de un paso para detectar residuos anti-microbianos en huevos.
EP1216307B2 (en) *	1999-10-04	2009-11-18	DSM IP Assets B.V.	Method for the detection of antimicrobial residues
WO2003033728A1 (en) *	2001-10-15	2003-04-24	Dsm Ip Assets B.V.	Apparatus and method for detecting undesired residues in a sample
CN100552038C (zh)	2003-09-11	2009-10-21	帝斯曼知识产权资产管理有限公司	血液和尿液检验方法
ATE528389T1 (de) *	2003-11-18	2011-10-15	Charm Sciences Inc	Hemmtestverfahren und -vorrichtung zum nachweis von antibiotika
ES2263361B1 (es) *	2004-11-30	2007-11-01	Universidad De Zaragoza	Metodo de deteccion de residuos de antibioticos y otros compuestos antibacterianos.
CN101379194B (zh)	2006-02-08	2014-10-22	帝斯曼知识产权资产管理有限公司	读取器与培养箱的组合
US20070218562A1 (en) *	2006-03-20	2007-09-20	Shulong Li	Color indicator for halamine treated fabric
US8476064B2 (en) *	2006-05-09	2013-07-02	Charm Sciences, Inc.	Inhibition assay method and device for detection of antibiotics
CN100554950C (zh) *	2007-09-29	2009-10-28	中国农业科学院上海兽医研究所	一种快速筛选牛奶类液体样中抗菌药物残留的方法
WO2011002856A2 (en) *	2009-07-01	2011-01-06	Biomerieux, Inc.	Method for neutralization of antibiotics in a culture medium
WO2013057182A1 (en)	2011-10-18	2013-04-25	Dsm Ip Assets B.V.	Method for the determination of the presence of an antibiotic in a fluid
US8709262B2 (en) *	2013-01-09	2014-04-29	King Abdulaziz University	Synthesizing and utilizing solar light activated nano-particle photocatalyst
US9732370B2 (en)	2013-05-02	2017-08-15	Dsm Ip Assets B.V.	Method for the determination of the presence of an antibiotic in a fluid
AU2016354916B2 (en)	2015-11-20	2019-03-07	Centrient Pharmaceuticals Netherlands B.V.	Assay for determining antibiotics in waste
ITUA20162034A1 (it) *	2016-03-25	2017-09-25	Mbd Diagnostics Ltd	Dispositivo e relativa composizione reagente per la diagnosi delle infezioni alle vie urinarie
CN112051345A (zh) *	2020-09-17	2020-12-08	河南省奶牛生产性能测定有限公司	一种生鲜乳中磺胺类药物的高效液相色检测方法

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Publication number	Priority date	Publication date	Assignee	Title
US3126325A (en) *		1964-03-24		Kzhpox
GB1467439A (en) *	1973-05-31	1977-03-16	Gist Brocades Nv	Method for determination of the presence of antibiotics
EP0000071B1 (en) *	1977-06-14	1981-08-05	The Wellcome Foundation Limited	Stabilised thymidine phosphorylase preparation and culture medium containing it
NL7806086A (nl) *	1978-06-05	1979-12-07	Gist Brocades Nv	Analyse-unit.
JPS5951997B2 (ja) *	1982-11-09	1984-12-17	森永乳業株式会社	ストレプトコツカス・サ−モフイルスに属する新規微生物及び該微生物を含有する組成物
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1994
- 1994-02-09 PT PT94200298T patent/PT611001E/pt unknown
- 1994-02-09 US US08/256,126 patent/US5494805A/en not_active Expired - Lifetime
- 1994-02-09 AU AU60396/94A patent/AU668023B2/en not_active Expired
- 1994-02-09 CZ CZ942510A patent/CZ251094A3/cs unknown
- 1994-02-09 CA CA002117890A patent/CA2117890A1/en not_active Abandoned
- 1994-02-09 HU HU9402921A patent/HUT67913A/hu unknown
- 1994-02-09 BR BR9403895A patent/BR9403895A/pt not_active IP Right Cessation
- 1994-02-09 NZ NZ261583A patent/NZ261583A/en not_active IP Right Cessation
- 1994-02-09 DE DE69430645T patent/DE69430645T2/de not_active Expired - Lifetime
- 1994-02-09 PL PL94305613A patent/PL179275B1/pl unknown
- 1994-02-09 KR KR1019940702535A patent/KR950700031A/ko not_active Application Discontinuation
- 1994-02-09 ES ES94200298T patent/ES2176220T3/es not_active Expired - Lifetime
- 1994-02-09 EP EP94200298A patent/EP0611001B1/en not_active Expired - Lifetime
- 1994-02-09 AT AT94200298T patent/ATE217910T1/de active
- 1994-02-09 WO PCT/EP1994/000359 patent/WO1994018343A1/en not_active Application Discontinuation
- 1994-02-09 DK DK94200298T patent/DK0611001T3/da active
- 1994-02-09 RU RU94045954/13A patent/RU94045954A/ru unknown
- 1994-02-09 RO RO94-01646A patent/RO114686B1/ro unknown
- 1994-02-10 UY UY23732A patent/UY23732A1/es unknown
- 1994-02-10 IL IL10861694A patent/IL108616A/xx not_active IP Right Cessation
- 1994-02-11 ZA ZA94959A patent/ZA94959B/xx unknown
- 1994-07-11 BG BG98900A patent/BG61400B1/bg unknown
- 1994-10-07 FI FI944709A patent/FI944709A/fi unknown

Also Published As

Publication number	Publication date
IL108616A (en)	1997-02-18
PL179275B1 (pl)	2000-08-31
CA2117890A1 (en)	1994-08-18
RU94045954A (ru)	1996-10-20
RO114686B1 (ro)	1999-06-30
FI944709A0 (fi)	1994-10-07
ES2176220T3 (es)	2002-12-01
AU668023B2 (en)	1996-04-18
CZ251094A3 (en)	1995-02-15
NZ261583A (en)	1995-07-26
DE69430645D1 (de)	2002-06-27
HUT67913A (en)	1995-05-29
BG98900A (bg)	1995-09-29
DE69430645T2 (de)	2002-09-05
PT611001E (pt)	2002-10-31
KR950700031A (ko)	1995-01-16
ATE217910T1 (de)	2002-06-15
WO1994018343A1 (en)	1994-08-18
HU9402921D0 (en)	1995-01-30
EP0611001A1 (en)	1994-08-17
PL305613A1 (en)	1995-01-23
BR9403895A (pt)	1999-06-01
AU6039694A (en)	1994-08-29
US5494805A (en)	1996-02-27
ZA94959B (en)	1994-08-23
IL108616A0 (en)	1994-05-30
UY23732A1 (es)	1994-02-18
FI944709A (fi)	1994-10-07
EP0611001B1 (en)	2002-05-22
DK0611001T3 (da)	2002-09-09

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