BE901702A - METHOD FOR CULTURING CELLS WITH GAS SPRING. - Google Patents

METHOD FOR CULTURING CELLS WITH GAS SPRING.

Info

Publication number
BE901702A
BE901702A BE0/214491A BE214491A BE901702A BE 901702 A BE901702 A BE 901702A BE 0/214491 A BE0/214491 A BE 0/214491A BE 214491 A BE214491 A BE 214491A BE 901702 A BE901702 A BE 901702A
Authority
BE
Belgium
Prior art keywords
gas spring
culturing cells
cells
medium
gas
Prior art date
Application number
BE0/214491A
Other languages
French (fr)
Inventor
R G Rupp
Original Assignee
Damon Biotech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Damon Biotech Inc filed Critical Damon Biotech Inc
Publication of BE901702A publication Critical patent/BE901702A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M25/00—Means for supporting, enclosing or fixing the microorganisms, e.g. immunocoatings
    • C12M25/16—Particles; Beads; Granular material; Encapsulation
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M27/00—Means for mixing, agitating or circulating fluids in the vessel
    • C12M27/02—Stirrer or mobile mixing elements
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/06—Nozzles; Sprayers; Spargers; Diffusers

Landscapes

  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Sustainable Development (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

Procédé de culture de cellules n'ayant pas de paroi, par lequel un gaz est introduit directement dans le milieu de culture (22) par une tete de barbotage (28), avec un débit suffisant pour que la concentration d'oxygène et d'anhydride carbonique reste constante dans le milieu. Les cellules sont encapsulées dans des membranes semiperméables qui les protègent contre les détériorations physiques. Application à la production de protéines et d'anticorps par des cultures cellulaires.Method for cultivating cells having no wall, by which a gas is introduced directly into the culture medium (22) by a bubbling head (28), with a flow rate sufficient for the concentration of oxygen and carbon dioxide remains constant in the medium. The cells are encapsulated in semipermeable membranes which protect them against physical deterioration. Application to the production of proteins and antibodies by cell cultures.

BE0/214491A 1984-02-13 1985-02-11 METHOD FOR CULTURING CELLS WITH GAS SPRING. BE901702A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US57949384A 1984-02-13 1984-02-13

Publications (1)

Publication Number Publication Date
BE901702A true BE901702A (en) 1985-05-29

Family

ID=24317121

Family Applications (1)

Application Number Title Priority Date Filing Date
BE0/214491A BE901702A (en) 1984-02-13 1985-02-11 METHOD FOR CULTURING CELLS WITH GAS SPRING.

Country Status (11)

Country Link
JP (1) JPS60199380A (en)
AU (1) AU572608B2 (en)
BE (1) BE901702A (en)
DE (1) DE3504748A1 (en)
DK (1) DK65085A (en)
FR (1) FR2559500A1 (en)
GB (1) GB2154246B (en)
IT (1) IT1184884B (en)
NL (1) NL8500351A (en)
NO (1) NO850534L (en)
SE (1) SE8500622L (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4724206A (en) * 1984-02-13 1988-02-09 Damon Biotech, Inc. Protein production using hypertonic media
US4829002A (en) * 1986-05-12 1989-05-09 Baxter International Inc. System for metering nutrient media to cell culture containers and method
EP0318487B1 (en) * 1986-08-04 1993-10-13 The University Of New South Wales Serum free tissue culture medium containing polymeric cell-protective agent
JPS6423888A (en) * 1987-07-16 1989-01-26 Etsuko Kakizaki Culture vessel with micro-cellular wall
JP2509630B2 (en) * 1987-07-29 1996-06-26 三井石油化学工業株式会社 Culture method and culture device
DE3739650C1 (en) * 1987-11-23 1989-05-24 Immuno Ag Fermenter for growing cell cultures
WO2005035748A1 (en) 2003-10-10 2005-04-21 Novo Nordisk Health Care Ag Method for large-scale production of a polypeptide in eukaryote cells and a culture vessel suitable therefor

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4352883A (en) * 1979-03-28 1982-10-05 Damon Corporation Encapsulation of biological material
US4409331A (en) * 1979-03-28 1983-10-11 Damon Corporation Preparation of substances with encapsulated cells
US4724206A (en) * 1984-02-13 1988-02-09 Damon Biotech, Inc. Protein production using hypertonic media

Also Published As

Publication number Publication date
FR2559500A1 (en) 1985-08-16
NL8500351A (en) 1985-09-02
DE3504748C2 (en) 1987-07-23
IT8567141A0 (en) 1985-02-12
GB8503248D0 (en) 1985-03-13
NO850534L (en) 1985-08-14
AU572608B2 (en) 1988-05-12
IT8567141A1 (en) 1986-08-12
DE3504748A1 (en) 1985-09-05
SE8500622L (en) 1985-08-14
IT1184884B (en) 1987-10-28
JPS6110115B2 (en) 1986-03-28
SE8500622D0 (en) 1985-02-12
GB2154246B (en) 1987-09-09
AU3857185A (en) 1985-08-22
DK65085A (en) 1985-08-14
GB2154246A (en) 1985-09-04
JPS60199380A (en) 1985-10-08
DK65085D0 (en) 1985-02-12

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Legal Events

Date Code Title Description
RE Patent lapsed

Owner name: DAMON BIOTECH INC.

Effective date: 19890228