BE846956A - Derives de 1-carbamoyl-k-fluorouracile et leur utilisation comme agents antineoplasiques, - Google Patents

Derives de 1-carbamoyl-k-fluorouracile et leur utilisation comme agents antineoplasiques,

Info

Publication number
BE846956A
BE846956A BE171252A BE171252A BE846956A BE 846956 A BE846956 A BE 846956A BE 171252 A BE171252 A BE 171252A BE 171252 A BE171252 A BE 171252A BE 846956 A BE846956 A BE 846956A
Authority
BE
Belgium
Prior art keywords
antineoplasics
fluorouracil
carbamoyl
derivatives
agents
Prior art date
Application number
BE171252A
Other languages
English (en)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of BE846956A publication Critical patent/BE846956A/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/52—Two oxygen atoms
    • C07D239/54—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals
    • C07D239/545—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals with other hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/553—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals with other hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms with halogen atoms or nitro radicals directly attached to ring carbon atoms, e.g. fluorouracil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
BE171252A 1975-11-05 1976-10-05 Derives de 1-carbamoyl-k-fluorouracile et leur utilisation comme agents antineoplasiques, BE846956A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/628,974 US4071519A (en) 1975-11-05 1975-11-05 1-Carbamoyl-5-fluorouracil derivatives

Publications (1)

Publication Number Publication Date
BE846956A true BE846956A (fr) 1977-01-31

Family

ID=24521080

Family Applications (1)

Application Number Title Priority Date Filing Date
BE171252A BE846956A (fr) 1975-11-05 1976-10-05 Derives de 1-carbamoyl-k-fluorouracile et leur utilisation comme agents antineoplasiques,

Country Status (10)

Country Link
US (1) US4071519A (fr)
JP (1) JPS5277073A (fr)
BE (1) BE846956A (fr)
DE (1) DE2639135C2 (fr)
DK (1) DK139969B (fr)
FI (1) FI61886C (fr)
FR (1) FR2330401A1 (fr)
GB (1) GB1524640A (fr)
NL (1) NL184469C (fr)
SE (1) SE422205B (fr)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GR68935B (fr) * 1976-03-31 1982-03-29 Takeda Chemical Industries Ltd
JPS5446791A (en) * 1977-09-22 1979-04-12 Takeda Chem Ind Ltd Fluorouracil derivative
US4349552A (en) * 1978-10-30 1982-09-14 Fujisawa Pharmaceutical Company, Ltd. 5-Fluorouracil derivatives, and their pharmaceutical compositions
JPS5785374A (en) * 1980-11-18 1982-05-28 Mitsui Toatsu Chem Inc 5-fluorouracil derivative and its preparation
JPS61204172A (ja) * 1985-03-07 1986-09-10 Nippon Kayaku Co Ltd ５−フルオロウラシル誘導体
EP0264080B1 (fr) * 1986-10-09 1992-08-26 Daikin Industries, Limited Dérivés du fluoro-5 uracile, composition pharmaceutique et application
JPH0273723U (fr) * 1988-11-26 1990-06-05
US8741858B2 (en) * 2007-09-21 2014-06-03 Zhongxu Ren Oligomer-nucleoside phosphate conjugates
WO2011109274A1 (fr) * 2010-03-01 2011-09-09 Concert Pharmaceuticals Inc. Dérivés de fluorouracile
WO2017123823A1 (fr) * 2016-01-12 2017-07-20 Bioelectron Technology Corporation Inhibiteurs de sulfure:quinone oxydoréductase alkyle, acyle, urée, et aza-uracile

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5324951B2 (fr) * 1973-11-28 1978-07-24

Also Published As

Publication number Publication date
JPS5277073A (en) 1977-06-29
DE2639135A1 (de) 1977-05-18
NL184469B (nl) 1989-03-01
FR2330401A1 (fr) 1977-06-03
DK139969B (da) 1979-05-28
US4071519A (en) 1978-01-31
FI61886B (fi) 1982-06-30
DE2639135C2 (de) 1983-04-14
JPS5549578B2 (fr) 1980-12-12
FR2330401B1 (fr) 1980-04-18
FI61886C (fi) 1982-10-11
NL184469C (nl) 1989-08-01
NL7608892A (nl) 1977-05-09
DK498676A (fr) 1977-05-06
DK139969C (fr) 1979-11-05
SE422205B (sv) 1982-02-22
GB1524640A (en) 1978-09-13
SE7607088L (sv) 1977-05-06

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Legal Events

Date Code Title Description
RE Patent lapsed

Owner name: MITSUI TOATSU CHEMICALS INC. (MITSUI TOATSU KAGAK

Effective date: 19921031