AU8513098A - Assays and peptide substrate for determining aggrecan degrading metallo proteaseactivity - Google Patents
Assays and peptide substrate for determining aggrecan degrading metallo proteaseactivityInfo
- Publication number
- AU8513098A AU8513098A AU85130/98A AU8513098A AU8513098A AU 8513098 A AU8513098 A AU 8513098A AU 85130/98 A AU85130/98 A AU 85130/98A AU 8513098 A AU8513098 A AU 8513098A AU 8513098 A AU8513098 A AU 8513098A
- Authority
- AU
- Australia
- Prior art keywords
- proteaseactivity
- assays
- determining
- peptide substrate
- metallo
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/573—Immunoassay; Biospecific binding assay; Materials therefor for enzymes or isoenzymes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4725—Proteoglycans, e.g. aggreccan
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
- C12Q1/37—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving peptidase or proteinase
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Wood Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Gastroenterology & Hepatology (AREA)
- Cell Biology (AREA)
- Toxicology (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Peptides Or Proteins (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/US1998/015436 WO2000005256A1 (en) | 1998-07-24 | 1998-07-24 | Assays and peptide substrate for determining aggrecan degrading metallo protease activity |
Publications (1)
Publication Number | Publication Date |
---|---|
AU8513098A true AU8513098A (en) | 2000-02-14 |
Family
ID=22267553
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU85130/98A Abandoned AU8513098A (en) | 1998-07-24 | 1998-07-24 | Assays and peptide substrate for determining aggrecan degrading metallo proteaseactivity |
Country Status (2)
Country | Link |
---|---|
AU (1) | AU8513098A (en) |
WO (1) | WO2000005256A1 (en) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20030166037A1 (en) * | 2002-01-16 | 2003-09-04 | Fourie Anne M. | Aggrecanase-1 and -2 peptide substrates and methods |
PL371525A1 (en) * | 2002-01-31 | 2005-06-27 | Wyeth | Aggrecanase molecules |
DE102004029470A1 (en) * | 2004-06-18 | 2006-01-05 | InViTek Gesellschaft für Biotechnik & Biodesign mbH | Method for determining aggrecanase activities |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5427954A (en) * | 1992-04-29 | 1995-06-27 | Shriner's Hospitals For Crippled Children | Compositions and methods for detection and treatment of human osteoarthritis |
AUPM666894A0 (en) * | 1994-07-07 | 1994-07-28 | University Of Melbourne, The | Diagnostic methods and compositions |
JP2000503533A (en) * | 1996-01-04 | 2000-03-28 | ネーデルランドセ・オルガニザテイエ・フール・テゲパスト―ナトウールベテンシヤツペリーク・オンデルツエク・テイエヌオー | Assay method for protease using fluorescent quenching substrate |
EP0785274B1 (en) * | 1996-01-18 | 2000-09-27 | Aventis Pharma Deutschland GmbH | An artifical recombinant substrate (rAGG-1) and native aggrecan to study the proteolytic activity of 'Aggrecanase' in cell culture systems |
-
1998
- 1998-07-24 WO PCT/US1998/015436 patent/WO2000005256A1/en active Application Filing
- 1998-07-24 AU AU85130/98A patent/AU8513098A/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
WO2000005256A1 (en) | 2000-02-03 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
MK6 | Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase |