AU7890598A - Fused pyrimidine compounds and medicinal use thereof - Google Patents

Fused pyrimidine compounds and medicinal use thereof

Info

Publication number
AU7890598A
AU7890598A AU78905/98A AU7890598A AU7890598A AU 7890598 A AU7890598 A AU 7890598A AU 78905/98 A AU78905/98 A AU 78905/98A AU 7890598 A AU7890598 A AU 7890598A AU 7890598 A AU7890598 A AU 7890598A
Authority
AU
Australia
Prior art keywords
pyrimidine compounds
medicinal use
fused pyrimidine
fused
medicinal
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU78905/98A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Welfide Corp
Original Assignee
Welfide Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Welfide Corp filed Critical Welfide Corp
Publication of AU7890598A publication Critical patent/AU7890598A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/86—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
    • C07D239/94—Nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/95—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in positions 2 and 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU78905/98A 1996-12-27 1997-12-22 Fused pyrimidine compounds and medicinal use thereof Abandoned AU7890598A (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
JP34923796 1996-12-27
JP8/349237 1996-12-27
JP7241097 1997-03-25
JP9/72410 1997-03-25
PCT/JP1997/004782 WO1998029397A1 (en) 1996-12-27 1997-12-22 Fused pyrimidine compounds and medicinal use thereof

Publications (1)

Publication Number Publication Date
AU7890598A true AU7890598A (en) 1998-07-31

Family

ID=26413541

Family Applications (1)

Application Number Title Priority Date Filing Date
AU78905/98A Abandoned AU7890598A (en) 1996-12-27 1997-12-22 Fused pyrimidine compounds and medicinal use thereof

Country Status (2)

Country Link
AU (1) AU7890598A (en)
WO (1) WO1998029397A1 (en)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK0977737T3 (en) * 1997-04-22 2004-01-26 Janssen Pharmaceutica Nv CRF antagonistic quino- and quinazoline
NL1010018C2 (en) * 1997-09-09 1999-03-10 Duphar Int Res Quinoline and quinazoline derivatives with corticotropin releasing factor (CRF) antagonistic effect.
US6472402B1 (en) 1998-04-02 2002-10-29 Neurogen Corporation Aminoalkyl substituted 5,6,7,8-Tetrahydro-9H-Pyridino [2,3-B]indole derivatives
WO1999051598A1 (en) * 1998-04-02 1999-10-14 Neurogen Corporation SUBSTITUTED 9H-PYRIDINO[2,3-b]INDOLE AND 9H-PYRIMIDINO[4,5-b]INDOLE DERIVATIVES: SELECTIVE NEUROPEPTIDE y RECEPTOR LIGANDS
US6147085A (en) * 1999-04-01 2000-11-14 Neurogen Corporation Aminoalkyl substituted 9H-pyridino[2,3-b] indole and 9H-pyrimidino[4,5-b] indole derivatives
JP2002510686A (en) 1998-04-02 2002-04-09 ニューロゲン コーポレイション 5,6,7,8-Tetrahydro-9H-pyridino [2,3-b] indole and 5,6,7,8-tetrahydro-9Hpyrimidino [4,5-B] indole derivatives substituted with aminoalkyl: CRF1 specific ligand
IL139787A0 (en) * 1998-06-02 2002-02-10 Osi Pharm Inc PYRROLO [2, 3d] PYRIMIDINE COMPOSITIONS AND THEIR USE
US6686366B1 (en) 1998-06-02 2004-02-03 Osi Pharmaceuticals, Inc. Compounds specific to adenosine A3 receptor and uses thereof
US6878716B1 (en) 1998-06-02 2005-04-12 Osi Pharmaceuticals, Inc. Compounds specific to adenosine A1 receptor and uses thereof
CA2371271A1 (en) * 1999-04-30 2000-11-09 Neurogen Corporation 9h-pyrimido[4,5-b]indole derivatives: crf1 specific ligands
US6432989B1 (en) 1999-08-27 2002-08-13 Pfizer Inc Use of CRF antagonists to treat circadian rhythm disorders
PL354784A1 (en) * 1999-09-30 2004-02-23 Neurogen Corporation Certain alkylene diamine-substituted heterocycles
US6664252B2 (en) 1999-12-02 2003-12-16 Osi Pharmaceuticals, Inc. 4-aminopyrrolo[2,3-d]pyrimidine compounds specific to adenosine A2a receptor and uses thereof
US6680322B2 (en) 1999-12-02 2004-01-20 Osi Pharmaceuticals, Inc. Compounds specific to adenosine A1 receptors and uses thereof
US7160890B2 (en) 1999-12-02 2007-01-09 Osi Pharmaceuticals, Inc. Compounds specific to adenosine A3 receptor and uses thereof
US6630476B2 (en) * 2000-07-07 2003-10-07 Bristol-Myers Squibb Pharma Company Pyrrolo [3,4-d] pyrimidines as corticotropin releasing factor (CRF) antagonists
US6673802B2 (en) 2000-12-01 2004-01-06 Osi Pharmaceuticals, Inc. Compounds specific to adenosine A3 receptor and uses thereof
US6680324B2 (en) 2000-12-01 2004-01-20 Osi Pharmaceuticals, Inc. Compounds specific to adenosine A1 receptors and uses thereof
JP4723115B2 (en) * 2001-05-23 2011-07-13 日本化薬株式会社 Adenylate cyclase type 5 inhibitor
DK1450811T3 (en) 2001-11-30 2010-02-15 Osi Pharm Inc Compounds specific for adenosine A1 and A3 receptors and uses thereof
CN1620294A (en) 2001-12-20 2005-05-25 Osi药物公司 Pyrimidine A2b selective antagonist compounds, their synthesis and use
DE60236458D1 (en) 2001-12-20 2010-07-01 Osi Pharm Inc PYRROLOPYRIMIDINE A2B SELECTIVE ANTAGONISTIC COMPOUNDS, THEIR SYNTHESIS AND USE
CN1809357B (en) * 2003-06-20 2010-12-22 科勒制药有限公司 Small molecule Toll-like receptor (TLR) antagonists
BRPI0411514A (en) * 2003-06-20 2006-08-01 Coley Pharm Gmbh small molecule toll-like receptor antagonists
SG122973A1 (en) 2003-10-30 2006-06-29 Coley Pharm Gmbh C-class oligonucleotide analogs with enhanced immunostimulatory potency
CA2569763C (en) * 2004-06-08 2013-03-12 Decode Chemistry, Inc. 2,4-diaminoquinazolines for spinal muscular atrophy
US7982035B2 (en) 2007-08-27 2011-07-19 Duquesne University Of The Holy Spirit Tricyclic compounds having antimitotic and/or antitumor activity and methods of use thereof
WO2011028741A1 (en) 2009-09-03 2011-03-10 Bristol-Myers Squibb Company Quinazolines as potassium ion channel inhibitors
TW201202230A (en) * 2010-05-24 2012-01-16 Mitsubishi Tanabe Pharma Corp Novel quinazoline compound
WO2012012712A2 (en) * 2010-07-23 2012-01-26 President And Fellows Of Harvard College Tricyclic proteasome activity enhancing compounds
CA2829939C (en) 2011-03-15 2020-10-13 Trius Therapeutics, Inc. Tricyclic gyrase inhibitors
EP2806875B1 (en) 2012-01-25 2017-07-19 Proteostasis Therapeutics, Inc. Proteasome activity modulating compounds
CN107353288B (en) * 2017-06-23 2019-10-18 吉林大学 4- ethamine (2- carboxyl) -9H- pyrimido [4,5-b] indoles and preparation method thereof

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL112249A (en) * 1994-01-25 2001-11-25 Warner Lambert Co Pharmaceutical compositions containing di and tricyclic pyrimidine derivatives for inhibiting tyrosine kinases of the epidermal growth factor receptor family and some new such compounds

Also Published As

Publication number Publication date
WO1998029397A1 (en) 1998-07-09

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