AU784196B2 - Improved transdermal contraceptive delivery system and process - Google Patents

Improved transdermal contraceptive delivery system and process Download PDF

Info

Publication number: AU784196B2
Authority: AU; Australia
Prior art keywords: delivery system; adhesive polymer; transdermal; polymer matrix; composition
Prior art date: 1999-11-24
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Ceased

Application number

AU17883/01A

Other languages

English (en)

Other versions

AU1788301A (en

Inventor

Te-Yen Chien

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Agile Therapeutics Inc

Original Assignee

Agile Therapeutics Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-11-24

Filing date

2000-11-22

Publication date

2006-02-23

2000-11-22 Application filed by Agile Therapeutics Inc filed Critical Agile Therapeutics Inc

2001-06-04 Publication of AU1788301A publication Critical patent/AU1788301A/en

2006-02-23 Application granted granted Critical

2006-02-23 Publication of AU784196B2 publication Critical patent/AU784196B2/en

2006-05-09 Priority to AU2006201918A priority Critical patent/AU2006201918B2/en

2020-11-22 Anticipated expiration legal-status Critical

Status Ceased legal-status Critical Current

Links

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
- A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
- A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
- A61K9/7061—Polyacrylates
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
- A61K31/567—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in position 17 alpha, e.g. mestranol, norethandrolone
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/18—Feminine contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/30—Oestrogens
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/20—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids

Landscapes

Health & Medical Sciences (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Dermatology (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Endocrinology (AREA)
Diabetes (AREA)
Reproductive Health (AREA)
Gynecology & Obstetrics (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicinal Preparation (AREA)

AU17883/01A 1999-11-24 2000-11-22 Improved transdermal contraceptive delivery system and process Ceased AU784196B2 (en)

Priority Applications (1)

Application Number	Priority Date	Filing Date	Title
AU2006201918A AU2006201918B2 (en)	1999-11-24	2006-05-09	Improved transdermal contraceptive delivery system and process

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US16753599P	1999-11-24	1999-11-24
US60/167535		1999-11-24
PCT/US2000/032043 WO2001037770A1 (en)	1999-11-24	2000-11-22	Improved transdermal contraceptive delivery system and process

Related Child Applications (1)

Application Number	Title	Priority Date	Filing Date
AU2006201918A Division AU2006201918B2 (en)	1999-11-24	2006-05-09	Improved transdermal contraceptive delivery system and process

Publications (2)

Publication Number	Publication Date
AU1788301A AU1788301A (en)	2001-06-04
AU784196B2 true AU784196B2 (en)	2006-02-23

Family

ID=22607771

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
AU17883/01A Ceased AU784196B2 (en)	1999-11-24	2000-11-22	Improved transdermal contraceptive delivery system and process
AU2006201918A Ceased AU2006201918B2 (en)	1999-11-24	2006-05-09	Improved transdermal contraceptive delivery system and process

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
AU2006201918A Ceased AU2006201918B2 (en)	1999-11-24	2006-05-09	Improved transdermal contraceptive delivery system and process

Country Status (21)

Country	Link
EP (1)	EP1242012B1 (ja)
JP (2)	JP4841781B2 (ja)
KR (1)	KR100758757B1 (ja)
CN (1)	CN1399533A (ja)
AR (1)	AR030037A1 (ja)
AT (1)	ATE453374T1 (ja)
AU (2)	AU784196B2 (ja)
BR (1)	BR0015802B1 (ja)
CA (1)	CA2391430C (ja)
CY (1)	CY1110615T1 (ja)
DE (1)	DE60043621D1 (ja)
DK (1)	DK1242012T3 (ja)
ES (1)	ES2338860T3 (ja)
IL (1)	IL149655A0 (ja)
MX (1)	MXPA02005224A (ja)
NO (1)	NO331218B1 (ja)
NZ (1)	NZ518723A (ja)
PT (1)	PT1242012E (ja)
TW (1)	TWI253350B (ja)
WO (1)	WO2001037770A1 (ja)
ZA (1)	ZA200203525B (ja)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US7045145B1 (en)	1999-11-24	2006-05-16	Agile Therapeutics, Inc.	Transdermal contraceptive delivery system and process
US7384650B2 (en)	1999-11-24	2008-06-10	Agile Therapeutics, Inc.	Skin permeation enhancement composition for transdermal hormone delivery system
DE10159120B4 (de) *	2001-12-01	2006-08-17	Lts Lohmann Therapie-Systeme Ag	Steroidhormonhaltige transdermale therapeutische Systeme enthaltend Propylenglycolmonocaprylat und seine Verwendung
AU2004212675B2 (en)	2003-02-21	2006-06-01	Bayer Intellectual Property Gmbh	UV stable transdermal therapeutic plaster
WO2004098517A2 (en) *	2003-05-02	2004-11-18	Duramed Pharmaceuticals, Inc.	Methods of hormonal treatment utilizing extended cycle contraceptive regimens
MEP23508A (en) *	2003-10-28	2010-06-10	Noven Pharma	Compositions and methods for comtrolling drug loss and delivery in transdermal drug delivery systems
US8668925B2 (en)	2003-12-12	2014-03-11	Bayer Intellectual Property Gmbh	Transdermal delivery of hormones without the need of penetration enhancers
UA89766C2 (en)	2003-12-12	2010-03-10	Байер Шеринг Фарма Акциенгезельшафт	Transdermal delivery system of gestodene
US20050202073A1 (en)	2004-03-09	2005-09-15	Mylan Technologies, Inc.	Transdermal systems containing multilayer adhesive matrices to modify drug delivery
US9205062B2 (en)	2004-03-09	2015-12-08	Mylan Pharmaceuticals, Inc.	Transdermal systems containing multilayer adhesive matrices to modify drug delivery
CN1313084C (zh) *	2004-11-05	2007-05-02	郑会义	一种透皮避孕药传送体系及制备方法
CN1318032C (zh) *	2005-01-24	2007-05-30	浙江大学	炔雌醇透皮吸收贴片
US8962013B2 (en)	2005-05-02	2015-02-24	Bayer Intellectual Property Gmbh	Multi-layered transdermal system with triazine UV absorber
US20080075779A1 (en) *	2006-09-27	2008-03-27	Chappa Ralph A	Additives And Methods For Enhancing Active Agent Elution Kinetics
GB0809905D0 (en) *	2008-06-02	2008-07-09	Secr Defence	A Transdermal drug delivery device
US20120263784A1 (en)	2009-10-12	2012-10-18	Lyka Labs Limited	Emergency contraceptive
CN103025320A (zh) *	2010-03-28	2013-04-03	伊万斯彻有限公司	***内药物递送装置
DE102010040299A1 (de)	2010-09-06	2012-03-08	Bayer Schering Pharma Aktiengesellschaft	Transdermale therapeutische Systeme mit kristallisationsinhibierender Schutzfolie (Release Liner)
US10028858B2 (en)	2011-07-11	2018-07-24	Medicines360	Intrauterine systems, IUD insertion devices, and related methods and kits therefor
WO2013067346A1 (en) *	2011-11-04	2013-05-10	Agile Therapeutics, Inc.	Dermal delivery compositions and methods
EP2934497B1 (en) *	2012-12-21	2016-11-23	Teikoku Pharma USA, Inc.	Compositions and methods for transdermal delivery of hormones and other medicinal agents
US9314470B2 (en)	2012-12-28	2016-04-19	Noven Pharmaceuticals, Inc.	Transdermal drug delivery systems for levonorgestrel and ethinyl estradiol

Citations (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5686097A (en) *	1993-09-29	1997-11-11	Alza Corporation	Monoglyceride/lactate ester permeation enhancer for codelivery of steroids
US5762956A (en) *	1996-04-24	1998-06-09	Rutgers, The State University Of New Jersey	Transdermal contraceptive delivery system and process
US5876746A (en) *	1995-06-07	1999-03-02	Cygnus, Inc.	Transdermal patch and method for administering 17-deacetyl norgestimate alone or in combination with an estrogen

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3632740A (en) *	1968-06-13	1972-01-04	Johnson & Johnson	Topical device for the therapeutic management of dermatological lesions with steroids
JPS5843368B2 (ja) *	1980-10-30	1983-09-27	日東電工株式会社	消炎鎮痛貼付剤
US5023084A (en) *	1986-12-29	1991-06-11	Rutgers, The State University Of New Jersey	Transdermal estrogen/progestin dosage unit, system and process
PT742011E (pt) *	1994-11-17	2002-10-31	Toray Industries	Preparacao que pode ser absorvida por via percutanea

2000
- 2000-11-22 BR BRPI0015802-0B1A patent/BR0015802B1/pt not_active IP Right Cessation
- 2000-11-22 ES ES00980651T patent/ES2338860T3/es not_active Expired - Lifetime
- 2000-11-22 KR KR1020027006580A patent/KR100758757B1/ko active IP Right Grant
- 2000-11-22 AU AU17883/01A patent/AU784196B2/en not_active Ceased
- 2000-11-22 IL IL14965500A patent/IL149655A0/xx not_active IP Right Cessation
- 2000-11-22 CA CA002391430A patent/CA2391430C/en not_active Expired - Fee Related
- 2000-11-22 DE DE60043621T patent/DE60043621D1/de not_active Expired - Lifetime
- 2000-11-22 PT PT00980651T patent/PT1242012E/pt unknown
- 2000-11-22 MX MXPA02005224A patent/MXPA02005224A/es active IP Right Grant
- 2000-11-22 AT AT00980651T patent/ATE453374T1/de active
- 2000-11-22 EP EP00980651A patent/EP1242012B1/en not_active Expired - Lifetime
- 2000-11-22 WO PCT/US2000/032043 patent/WO2001037770A1/en active IP Right Grant
- 2000-11-22 NZ NZ518723A patent/NZ518723A/en not_active IP Right Cessation
- 2000-11-22 JP JP2001539387A patent/JP4841781B2/ja not_active Expired - Fee Related
- 2000-11-22 DK DK00980651.4T patent/DK1242012T3/da active
- 2000-11-22 CN CN00816271A patent/CN1399533A/zh active Pending
- 2000-11-23 AR ARP000106197A patent/AR030037A1/es not_active Application Discontinuation
2001
- 2001-01-03 TW TW089124926A patent/TWI253350B/zh not_active IP Right Cessation
2002
- 2002-05-03 ZA ZA200203525A patent/ZA200203525B/xx unknown
- 2002-05-22 NO NO20022420A patent/NO331218B1/no not_active IP Right Cessation
2006
- 2006-05-09 AU AU2006201918A patent/AU2006201918B2/en not_active Ceased
2010
- 2010-03-22 CY CY20101100276T patent/CY1110615T1/el unknown
2011
- 2011-07-25 JP JP2011161744A patent/JP2011231125A/ja active Pending

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5686097A (en) *	1993-09-29	1997-11-11	Alza Corporation	Monoglyceride/lactate ester permeation enhancer for codelivery of steroids
US5876746A (en) *	1995-06-07	1999-03-02	Cygnus, Inc.	Transdermal patch and method for administering 17-deacetyl norgestimate alone or in combination with an estrogen
US5762956A (en) *	1996-04-24	1998-06-09	Rutgers, The State University Of New Jersey	Transdermal contraceptive delivery system and process

Also Published As

Publication number	Publication date
KR100758757B1 (ko)	2007-09-14
NO331218B1 (no)	2011-11-07
IL149655A0 (en)	2002-11-10
JP2003533434A (ja)	2003-11-11
CA2391430C (en)	2009-10-06
DK1242012T3 (da)	2010-04-26
ATE453374T1 (de)	2010-01-15
ZA200203525B (en)	2003-07-18
NO20022420D0 (no)	2002-05-22
TWI253350B (en)	2006-04-21
NZ518723A (en)	2004-04-30
CY1110615T1 (el)	2015-04-29
EP1242012A4 (en)	2006-05-31
BR0015802B1 (pt)	2014-04-29
DE60043621D1 (de)	2010-02-11
BR0015802A (pt)	2003-06-24
NO20022420L (no)	2002-07-18
CA2391430A1 (en)	2001-05-31
AU1788301A (en)	2001-06-04
MXPA02005224A (es)	2003-09-25
AU2006201918B2 (en)	2009-07-30
WO2001037770A1 (en)	2001-05-31
PT1242012E (pt)	2010-03-31
KR20020072280A (ko)	2002-09-14
JP4841781B2 (ja)	2011-12-21
CN1399533A (zh)	2003-02-26
JP2011231125A (ja)	2011-11-17
AU2006201918A1 (en)	2006-06-01
EP1242012A1 (en)	2002-09-25
ES2338860T3 (es)	2010-05-13
AR030037A1 (es)	2003-08-13
EP1242012B1 (en)	2009-12-30

Legal Events

Date	Code	Title	Description
2003-05-01	MK1	Application lapsed section 142(2)(a) - no request for examination in relevant period
2004-01-29	NA	Applications received for extensions of time, section 223	Free format text: AN APPLICATION TO EXTEND THE TIME FROM 20030401 TO 20031001 IN WHICH TO REQUEST EXAMINATION HAS BEEN LODGED
2004-03-25	NB	Applications allowed - extensions of time section 223(2)	Free format text: THE TIME IN WHICH TO REQUEST EXAMINATION HAS BEEN EXTENDED TO 20031001