AU6975591A - Pharmaceutical composition for treating or preventing retroviral infections - Google Patents

Pharmaceutical composition for treating or preventing retroviral infections

Info

Publication number
AU6975591A
AU6975591A AU69755/91A AU6975591A AU6975591A AU 6975591 A AU6975591 A AU 6975591A AU 69755/91 A AU69755/91 A AU 69755/91A AU 6975591 A AU6975591 A AU 6975591A AU 6975591 A AU6975591 A AU 6975591A
Authority
AU
Australia
Prior art keywords
treating
pharmaceutical composition
retroviral infections
preventing retroviral
arg
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
AU69755/91A
Inventor
Bruno Guy
Jean-Pierre Lecocq
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Transgene SA
Original Assignee
Transgene SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR9013102A external-priority patent/FR2668065B1/en
Application filed by Transgene SA filed Critical Transgene SA
Publication of AU6975591A publication Critical patent/AU6975591A/en
Granted legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/55—Protease inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals

Abstract

A pharmaceutical composition for treating or preventing retroviral diseases containing a thiol-protease inhibitor as an active principle. Thiol-protease inhibitors are known products such as cystatines and the derivatives thereof, antipaine [(S)-1-carboxy-2-phenyletyl]-carbamoyl-Arg-Val-Arg-al, E-64 (L-trans-epoxysuccinyl-leucylamide-(4-guanidino)-butane, N-[N-(L-3-transcarboxyirane-2-carbonyl)-L-leucyl]-agmatine, leupeptin, iodoacetic acid/iodoacetamide or N-Cbz-Phe-Ala-diazomethane.
AU69755/91A 1989-12-18 1990-12-18 Pharmaceutical composition for treating or preventing retroviral infections Granted AU6975591A (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
FR8916726 1989-12-18
FR8916726 1989-12-18
FR9013102 1990-10-23
FR9013102A FR2668065B1 (en) 1990-10-23 1990-10-23 PHARMACEUTICAL COMPOSITION FOR THE TREATMENT AND PREVENTION OF RETROVIRAL INFECTIONS.

Publications (1)

Publication Number Publication Date
AU6975591A true AU6975591A (en) 1991-07-18

Family

ID=26227737

Family Applications (2)

Application Number Title Priority Date Filing Date
AU69755/91A Ceased AU644621B2 (en) 1989-12-18 1990-12-18 Pharmaceutical composition for treating or preventing retroviral infections
AU69755/91A Granted AU6975591A (en) 1989-12-18 1990-12-18 Pharmaceutical composition for treating or preventing retroviral infections

Family Applications Before (1)

Application Number Title Priority Date Filing Date
AU69755/91A Ceased AU644621B2 (en) 1989-12-18 1990-12-18 Pharmaceutical composition for treating or preventing retroviral infections

Country Status (8)

Country Link
EP (1) EP0506769B1 (en)
JP (1) JPH05502868A (en)
AT (1) ATE109006T1 (en)
AU (2) AU644621B2 (en)
CA (1) CA2071972A1 (en)
DE (1) DE69011130T2 (en)
DK (1) DK0506769T3 (en)
WO (1) WO1991008769A1 (en)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5679688A (en) * 1992-03-11 1997-10-21 Narhex Limited Quinaldoyl-amine derivatives of oxo-and hydroxy-substituted hydrocarbons
US5888992A (en) * 1992-03-11 1999-03-30 Narhex Limited Polar substituted hydrocarbons
US6071895A (en) * 1992-03-11 2000-06-06 Narhex Limited Polar-substituted hydrocarbons
US6258806B1 (en) 1992-03-11 2001-07-10 Narhex Limited Amine derivatives of oxo- and hydroxy- substituted hydrocarbons

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU3604093A (en) * 1992-02-07 1993-09-03 United States Of America, Represented By The Secretary, Department Of Health And Human Services, The Use of 5,5'-dithio-bis(2-nitrobenzoic acid) for inhibition of HIV protease
KR100273620B1 (en) * 1992-09-09 2000-12-15 스티븐 엠. 오드리 Inhibition of retrovirus infection
FR2778851B1 (en) * 1998-05-19 2002-07-26 Aetsrn COMPOSITION BASED ON CYSTEINE PROTEASE INHIBITORS FOR DELAYING SENESCENCE, SELF-DESTRUCTION AND HEMOLYSIS OF ERYTHROCYTES
WO2005011649A2 (en) * 2003-05-19 2005-02-10 Vanderbilt University Methods of treating severe acute respiratory syndrome virus infections
US8232240B2 (en) 2005-02-23 2012-07-31 The Brigham And Women's Hospital, Inc. Inhibitors of enveloped virus infectivity

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
YU43397B (en) * 1985-01-16 1989-06-30 Inst Jozef Stefan Process for insulation of poultry eggs cystatine from egg-white
EP0269311A3 (en) * 1986-11-17 1990-06-06 Merck & Co. Inc. Methods of treating bone diseases by administration of a cysteine proteinase inhibitor

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5679688A (en) * 1992-03-11 1997-10-21 Narhex Limited Quinaldoyl-amine derivatives of oxo-and hydroxy-substituted hydrocarbons
US5888992A (en) * 1992-03-11 1999-03-30 Narhex Limited Polar substituted hydrocarbons
US5942504A (en) * 1992-03-11 1999-08-24 Narhex Limited Amine derivatives of oxo- and hydroxy- substituted hydrocarbons
US6071895A (en) * 1992-03-11 2000-06-06 Narhex Limited Polar-substituted hydrocarbons
US6258806B1 (en) 1992-03-11 2001-07-10 Narhex Limited Amine derivatives of oxo- and hydroxy- substituted hydrocarbons

Also Published As

Publication number Publication date
WO1991008769A1 (en) 1991-06-27
CA2071972A1 (en) 1991-06-19
DE69011130T2 (en) 1995-03-16
EP0506769A1 (en) 1992-10-07
AU644621B2 (en) 1993-12-16
JPH05502868A (en) 1993-05-20
DK0506769T3 (en) 1994-11-28
ATE109006T1 (en) 1994-08-15
EP0506769B1 (en) 1994-07-27
DE69011130D1 (en) 1994-09-01

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