AU563351B2 - Synthesis of oligosaccharides - Google Patents
Synthesis of oligosaccharidesInfo
- Publication number
- AU563351B2 AU563351B2 AU10397/83A AU1039783A AU563351B2 AU 563351 B2 AU563351 B2 AU 563351B2 AU 10397/83 A AU10397/83 A AU 10397/83A AU 1039783 A AU1039783 A AU 1039783A AU 563351 B2 AU563351 B2 AU 563351B2
- Authority
- AU
- Australia
- Prior art keywords
- oligosaccharides
- synthesis
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired, expires
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
- C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
- C08B37/0075—Heparin; Heparan sulfate; Derivatives thereof, e.g. heparosan; Purification or extraction methods thereof
- C08B37/0078—Degradation products
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H11/00—Compounds containing saccharide radicals esterified by inorganic acids; Metal salts thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H3/00—Compounds containing only hydrogen atoms and saccharide radicals having only carbon, hydrogen, and oxygen atoms
- C07H3/06—Oligosaccharides, i.e. having three to five saccharide radicals attached to each other by glycosidic linkages
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H7/00—Compounds containing non-saccharide radicals linked to saccharide radicals by a carbon-to-carbon bond
- C07H7/02—Acyclic radicals
- C07H7/033—Uronic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H9/00—Compounds containing a hetero ring sharing at least two hetero atoms with a saccharide radical
- C07H9/02—Compounds containing a hetero ring sharing at least two hetero atoms with a saccharide radical the hetero ring containing only oxygen as ring hetero atoms
- C07H9/04—Cyclic acetals
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Materials Engineering (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Polymers & Plastics (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (22)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR8200621 | 1982-01-15 | ||
FR8200621A FR2519987A1 (en) | 1982-01-15 | 1982-01-15 | Uronic acid derivs. - useful as glycoside intermediates or hapten(s) |
FR8201575 | 1982-02-01 | ||
FR8201575A FR2520744A1 (en) | 1982-02-01 | 1982-02-01 | Uronic acid derivs. - useful as glycoside intermediates or hapten(s) |
FR8202526A FR2521566A1 (en) | 1982-02-16 | 1982-02-16 | Antithrombotic oligosaccharide fragments of muco-polysaccharide prodn. - by reacting uronic acid and glucosamine units |
FR8202526 | 1982-02-16 | ||
FR8209392A FR2527614A1 (en) | 1982-05-28 | 1982-05-28 | Uronic acid derivs. - useful as glycoside intermediates or hapten(s) |
FR8209392 | 1982-05-28 | ||
FR8210892A FR2528854A1 (en) | 1982-06-22 | 1982-06-22 | Antithrombotic oligosaccharide fragments of muco-polysaccharide prodn. - by reacting uronic acid and glucosamine units |
FR8210891 | 1982-06-22 | ||
FR8210892 | 1982-06-22 | ||
FR8210891A FR2528853A1 (en) | 1982-06-22 | 1982-06-22 | Antithrombotic oligosaccharide fragments of muco-polysaccharide prodn. - by reacting uronic acid and glucosamine units |
FR8211679A FR2529557A1 (en) | 1982-07-02 | 1982-07-02 | New disaccharides containing an alpha -L-idopyranose unit, and their preparation |
FR8211679 | 1982-07-02 | ||
FR8213804 | 1982-08-06 | ||
FR8213804A FR2531436A1 (en) | 1982-08-06 | 1982-08-06 | Substituted pentasaccharides possessing biological properties, their preparation and their uses as medicaments |
FR8215803A FR2533219A1 (en) | 1982-09-20 | 1982-09-20 | New disaccharides composed of units having a D-glucosamine and L-iduronic acid structure and method for preparing them |
FR8215804A FR2533220A1 (en) | 1982-09-20 | 1982-09-20 | New disaccharides composed of units having a D-glucuronic acid and D-glucosamine structure and method for preparing them |
FR8215803 | 1982-09-20 | ||
FR8215804 | 1982-09-20 | ||
FR8218003 | 1982-10-27 | ||
FR8218303A FR2535306A1 (en) | 1982-10-28 | 1982-10-28 | Improved station for sewage purification |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU42637/85A Addition AU582362B2 (en) | 1984-05-16 | 1985-05-16 | Novel oligosaccharides,their preparation synthesis and their biological applications |
Publications (3)
Publication Number | Publication Date |
---|---|
AU1039783A AU1039783A (en) | 1983-07-21 |
AU563351B2 true AU563351B2 (en) | 1987-07-09 |
AU563351C AU563351C (en) | 2003-06-19 |
Family
ID=27581615
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU10397/83A Expired AU563351C (en) | 1982-01-15 | 1983-01-14 | Synthesis of oligosaccharides |
Country Status (4)
Country | Link |
---|---|
EP (1) | EP0084999B1 (en) |
AU (1) | AU563351C (en) |
LU (1) | LU90928I2 (en) |
NL (1) | NL300093I2 (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU582362B2 (en) * | 1984-05-16 | 1989-03-23 | Sanofi-Synthelabo | Novel oligosaccharides,their preparation synthesis and their biological applications |
Families Citing this family (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2535324A1 (en) * | 1982-10-27 | 1984-05-04 | Choay Sa | PERFECTED STATION FOR THE PURIFICATION OF WASTEWATER |
US4801583A (en) * | 1982-01-15 | 1989-01-31 | Choay S.A. | Oligosaccharides and their biological applications |
FR2548189B1 (en) * | 1983-07-01 | 1986-04-11 | Choay Sa | NEW PRODUCTS CONTAINING OLIGOSACCHARIDES, THEIR PREPARATION AND THEIR BIOLOGICAL AND BIOCHEMICAL APPLICATIONS |
SE8501022L (en) * | 1985-03-01 | 1986-09-02 | Pharmacia Ab | FORMAT CREATES AND PROCEDURES FOR ITS PREPARATION |
GB8519416D0 (en) * | 1985-08-01 | 1985-09-04 | Unilever Plc | Oligosaccharides |
EP0300099A1 (en) * | 1987-07-20 | 1989-01-25 | Akzo N.V. | New pentasaccharides |
EP0347964A1 (en) * | 1988-06-21 | 1989-12-27 | Akzo N.V. | New oligosaccharides with internal spacer |
JPH0296588A (en) * | 1988-09-29 | 1990-04-09 | Rikagaku Kenkyusho | Sulfated oligosaccharide and relating substance thereof |
FR2636967B1 (en) * | 1988-09-29 | 1990-12-07 | Sanofi Sa | METHOD FOR DETERMINING ANIONIC SULPHATE POLYOSIDES, AND CASE FOR CARRYING OUT SAID METHOD |
US5476924A (en) * | 1989-01-27 | 1995-12-19 | Duke University | Protecting group for acetals and methods of using the same in the activation of saccharides |
US5707973A (en) * | 1991-04-23 | 1998-01-13 | Rhone-Poulenc Rorer S.A. | Sulfated polysaccharids for treatment or prevention of thromboses |
JPH08506322A (en) * | 1992-11-10 | 1996-07-09 | イエダ リサーチ アンド ディベロップメント カンパニー リミテッド | Compositions for modulating cytokine activity |
CA2199642C (en) * | 1997-03-10 | 2001-05-08 | Roger Cariou | Compositions containing an association of aspirin and an anti-xa oligosaccharide and use of an anti-xa oligosaccharide optionally in combination with aspirin |
CA2289522A1 (en) * | 1997-05-27 | 1998-12-03 | Akzo Nobel Nv | Use of oligosaccharide for preventing blood clotting in extracorporeal blood circuits |
AUPO888497A0 (en) * | 1997-09-01 | 1997-09-25 | Australian National University, The | Use of sulfated oligosaccharides as inhibitors of cardiovascular disease |
AUPO976897A0 (en) * | 1997-10-14 | 1997-11-06 | Australian National University, The | Use of sulfated oligosaccharides in lowering blood triglyceride levels |
FR2800074B1 (en) * | 1999-10-22 | 2001-12-21 | Aventis Pharma Sa | NOVEL OLIGOSACCHARIDES, THEIR PREPARATION AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM |
FR2814463B1 (en) * | 2000-09-22 | 2002-11-15 | Sanofi Synthelabo | NOVEL POLYSACCHARIDES WITH ANTITHROMBOTIC ACTIVITY COMPRISING AT LEAST ONE COVALENT BINDING WITH BIOTIN OR A BIOTINE DERIVATIVE |
CN1558911B (en) | 2001-09-07 | 2010-05-12 | 阿尔开密亚有限公司 | Synthetic heparin pentasaccharides |
CN1317287C (en) * | 2003-04-18 | 2007-05-23 | 山东大学 | Oligose polysulfate and preparation process thereof |
FR2874924B1 (en) | 2004-09-09 | 2006-12-01 | Sanofi Aventis Sa | BIOTINYLATED HEXADECASACCHARIDES, THEIR PREPARATION AND THEIR THERAPEUTIC USE |
CN103333264B (en) | 2008-05-30 | 2016-06-08 | 动量制药公司 | The method of sugar structure and manufacture and this class formation of use |
CN109734757B (en) * | 2019-03-11 | 2020-09-11 | 淮北师范大学 | Preparation method of related substance B of fondaparinux sodium injection |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA1136620A (en) * | 1979-01-08 | 1982-11-30 | Ulf P.F. Lindahl | Heparin fragments having selective anticoagulation activity |
IL61201A (en) * | 1979-10-05 | 1984-09-30 | Choay Sa | Oligosaccharides having no more than 8 saccharide moieties,their obtention from heparin and pharmaceutical compositions containing them |
CA1171375A (en) * | 1980-09-15 | 1984-07-24 | Ulf P.F. Lindahl | Oligosaccharides having selective anticoagulation activity |
FR2504535B1 (en) * | 1981-04-28 | 1987-08-14 | Choay Sa | DISACCHARIDES DERIVED FROM URONIC ACID AND GLUCOSAMINE AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM FOR THE CONTROL OF BLOOD COAGULATION |
-
1983
- 1983-01-14 AU AU10397/83A patent/AU563351C/en not_active Expired
- 1983-01-17 EP EP83400110A patent/EP0084999B1/en not_active Expired
-
2002
- 2002-06-07 LU LU90928C patent/LU90928I2/en unknown
- 2002-07-09 NL NL300093C patent/NL300093I2/en unknown
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU582362B2 (en) * | 1984-05-16 | 1989-03-23 | Sanofi-Synthelabo | Novel oligosaccharides,their preparation synthesis and their biological applications |
Also Published As
Publication number | Publication date |
---|---|
LU90928I2 (en) | 2002-08-07 |
NL300093I1 (en) | 2002-09-02 |
EP0084999B1 (en) | 1988-04-13 |
AU563351C (en) | 2003-06-19 |
NL300093I2 (en) | 2002-11-01 |
AU1039783A (en) | 1983-07-21 |
EP0084999A1 (en) | 1983-08-03 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
HB | Alteration of name in register |
Owner name: SANOFI-SYNTHELABO Free format text: FORMER NAME WAS: CHOAY S.A. |
|
NC | Extension of term for standard patent requested (sect. 70) |
Free format text: PRODUCT NAME: ARIXTRA (FONDAPARINUX SODIUM) |
|
PC | Assignment registered |
Owner name: SANOFI-SYNTHELABO Free format text: FORMER OWNER WAS: SOCIETE CIVILE DE GESTION DE PROPRIETE INDUSTRIELLE CHOAY "DROPIC" |
|
DA2 | Applications for amendment section 104 |
Free format text: THE NATURE OF THE PROPOSED AMENDMENT IS AS SHOWN IN THE STATEMENT(S) FILED 20020513 |
|
NDA | Extension of term for standard patent accepted (sect.70) |
Free format text: PRODUCT NAME: ARIXTRA (FONDAPARINUX SODIUM) Extension date: 20080114 |
|
DA3 | Amendments made section 104 |
Free format text: THE NATURE OF THE AMENDMENT IS AS WAS NOTIFIED IN THE OFFICIAL JOURNAL DATED 20030109 |
|
NDB | Extension of term for standard patent granted (sect.76) |
Free format text: PRODUCT NAME: ARIXTRA (FONDAPARINUX SODIUM) Extension date: 20080114 |