AU556589B2 - 2,4,6-trimethoxy phenyl-3-hexamethylene-iminopropyl-ketone - Google Patents
2,4,6-trimethoxy phenyl-3-hexamethylene-iminopropyl-ketoneInfo
- Publication number
- AU556589B2 AU556589B2 AU20568/83A AU2056883A AU556589B2 AU 556589 B2 AU556589 B2 AU 556589B2 AU 20568/83 A AU20568/83 A AU 20568/83A AU 2056883 A AU2056883 A AU 2056883A AU 556589 B2 AU556589 B2 AU 556589B2
- Authority
- AU
- Australia
- Prior art keywords
- ketone
- iminopropyl
- hexamethylene
- trimethoxy phenyl
- hexamethyleneiminopropyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
- 150000003839 salts Chemical class 0.000 abstract 2
- SOKKYQNPGLERHO-UHFFFAOYSA-N 4-(azepan-1-yl)-1-(2,4,6-trimethoxyphenyl)butan-1-one Chemical compound COC1=CC(OC)=CC(OC)=C1C(=O)CCCN1CCCCCC1 SOKKYQNPGLERHO-UHFFFAOYSA-N 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 231100000252 nontoxic Toxicity 0.000 abstract 1
- 230000003000 nontoxic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/10—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms
- C07D295/104—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/108—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D295/145—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/15—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Cardiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Heart & Thoracic Surgery (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
1. Claims for the contracting state AT Use of the (2,4,6-trimethoxyphenyl)-3-(hexamethyleneiminopropyl)-ketone having the following structural formula see diagramm : EP0110748,P6,F1 and its non toxic addition salts, for the manufacture of a medicine. 1. Claims for the contracting states BE, CH, DE, FR, GB, IT, LI, LU, NL, SE, The (2,4,6-trimethoxyphenyl)-(3-hexamethyleneiminopropyl)-ketone having the following structural formula see diagramm : EP0110748,P7,F1 and its addition salts.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR8217937 | 1982-10-26 | ||
FR8217937A FR2534916B1 (en) | 1982-10-26 | 1982-10-26 | NOVEL PHENYL- (3-AMINOPROPYL) -CETONE DERIVATIVES, USE IN THERAPEUTICS AND PREPARATION METHOD |
Publications (2)
Publication Number | Publication Date |
---|---|
AU2056883A AU2056883A (en) | 1984-05-03 |
AU556589B2 true AU556589B2 (en) | 1986-11-13 |
Family
ID=9278617
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU20568/83A Ceased AU556589B2 (en) | 1982-10-26 | 1983-10-25 | 2,4,6-trimethoxy phenyl-3-hexamethylene-iminopropyl-ketone |
Country Status (11)
Country | Link |
---|---|
EP (1) | EP0110748B1 (en) |
JP (1) | JPS5995283A (en) |
AT (1) | ATE26712T1 (en) |
AU (1) | AU556589B2 (en) |
CA (1) | CA1212944A (en) |
DE (1) | DE3371077D1 (en) |
DK (1) | DK156003C (en) |
ES (1) | ES8406069A1 (en) |
FR (1) | FR2534916B1 (en) |
GR (1) | GR79617B (en) |
IE (1) | IE56129B1 (en) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2584715B1 (en) * | 1985-07-10 | 1987-10-09 | Lafon Labor | PHENYL- (3-HEXAMETHYLENEIMINOPROPYL) -CETONE, PROCESS FOR PREPARATION AND THERAPEUTIC USE |
HUT74870A (en) * | 1993-05-26 | 1997-02-28 | Syntex Inc | Process for producing 1-phenylalkanone 5-ht4 receptor ligands and pharmaceutical compositions containing them |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR6945M (en) * | 1967-12-22 | 1969-05-12 | ||
FR2092133B1 (en) * | 1970-05-06 | 1974-03-22 | Orsymonde | |
FR2101045A1 (en) * | 1970-08-12 | 1972-03-31 | Penciolelli Madeleine | Omega-dialkylamino-1-(2,4,6-trialkoxy phenyl) alkan-1-ones - with vasodilator and spasmolytic activity |
FR2134218A1 (en) * | 1971-04-27 | 1972-12-08 | Penciolelli Madeleine | Phloroglucinol aminoketones - vasodilators and antispasmodics |
-
1982
- 1982-10-26 FR FR8217937A patent/FR2534916B1/en not_active Expired
-
1983
- 1983-10-18 GR GR72730A patent/GR79617B/el unknown
- 1983-10-24 CA CA000439563A patent/CA1212944A/en not_active Expired
- 1983-10-24 IE IE2488/83A patent/IE56129B1/en not_active IP Right Cessation
- 1983-10-25 DK DK489283A patent/DK156003C/en not_active IP Right Cessation
- 1983-10-25 EP EP83402070A patent/EP0110748B1/en not_active Expired
- 1983-10-25 AU AU20568/83A patent/AU556589B2/en not_active Ceased
- 1983-10-25 AT AT83402070T patent/ATE26712T1/en not_active IP Right Cessation
- 1983-10-25 ES ES526736A patent/ES8406069A1/en not_active Expired
- 1983-10-25 DE DE8383402070T patent/DE3371077D1/en not_active Expired
- 1983-10-26 JP JP58199310A patent/JPS5995283A/en active Pending
Also Published As
Publication number | Publication date |
---|---|
ES526736A0 (en) | 1984-07-01 |
DK156003B (en) | 1989-06-12 |
EP0110748A1 (en) | 1984-06-13 |
EP0110748B1 (en) | 1987-04-22 |
JPS5995283A (en) | 1984-06-01 |
DE3371077D1 (en) | 1987-05-27 |
DK489283A (en) | 1984-04-27 |
ATE26712T1 (en) | 1987-05-15 |
FR2534916B1 (en) | 1985-11-22 |
IE832488L (en) | 1984-04-26 |
IE56129B1 (en) | 1991-04-24 |
ES8406069A1 (en) | 1984-07-01 |
AU2056883A (en) | 1984-05-03 |
CA1212944A (en) | 1986-10-21 |
DK156003C (en) | 1989-11-13 |
GR79617B (en) | 1984-10-31 |
FR2534916A1 (en) | 1984-04-27 |
DK489283D0 (en) | 1983-10-25 |
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