AU5322601A - Bile acid containing prodrugs with enhanced bioavailability - Google Patents
Bile acid containing prodrugs with enhanced bioavailabilityInfo
- Publication number
- AU5322601A AU5322601A AU5322601A AU5322601A AU5322601A AU 5322601 A AU5322601 A AU 5322601A AU 5322601 A AU5322601 A AU 5322601A AU 5322601 A AU5322601 A AU 5322601A AU 5322601 A AU5322601 A AU 5322601A
- Authority
- AU
- Australia
- Prior art keywords
- acid containing
- bile acid
- containing prodrugs
- enhanced bioavailability
- bioavailability
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
- C07J43/003—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
- A61K47/554—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound the modifying agent being a steroid plant sterol, glycyrrhetic acid, enoxolone or bile acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
- C07J41/0055—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the 17-beta position being substituted by an uninterrupted chain of at least three carbon atoms which may or may not be branched, e.g. cholane or cholestane derivatives, optionally cyclised, e.g. 17-beta-phenyl or 17-beta-furyl derivatives
- C07J41/0061—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the 17-beta position being substituted by an uninterrupted chain of at least three carbon atoms which may or may not be branched, e.g. cholane or cholestane derivatives, optionally cyclised, e.g. 17-beta-phenyl or 17-beta-furyl derivatives one of the carbon atoms being part of an amide group
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
- C07J9/005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane containing a carboxylic function directly attached or attached by a chain containing only carbon atoms to the cyclopenta[a]hydrophenanthrene skeleton
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Cardiology (AREA)
- Hospice & Palliative Care (AREA)
- Virology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Heart & Thoracic Surgery (AREA)
- Botany (AREA)
- Epidemiology (AREA)
- Steroid Compounds (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US19585400P | 2000-04-07 | 2000-04-07 | |
US26990601P | 2001-02-21 | 2001-02-21 | |
PCT/US2001/011327 WO2001076531A2 (en) | 2000-04-07 | 2001-04-06 | Bile acid containing prodrugs with enhanced bioavailability |
Publications (1)
Publication Number | Publication Date |
---|---|
AU5322601A true AU5322601A (en) | 2001-10-23 |
Family
ID=26891401
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU5322601A Pending AU5322601A (en) | 2000-04-07 | 2001-04-06 | Bile acid containing prodrugs with enhanced bioavailability |
AU2001253226A Ceased AU2001253226B2 (en) | 2000-04-07 | 2001-04-06 | Bile acid containing prodrugs with enhanced bioavailability |
AU2006202213A Abandoned AU2006202213A1 (en) | 2000-04-07 | 2006-05-25 | Bile acid containing prodrugs with enhanced bioavailability |
Family Applications After (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU2001253226A Ceased AU2001253226B2 (en) | 2000-04-07 | 2001-04-06 | Bile acid containing prodrugs with enhanced bioavailability |
AU2006202213A Abandoned AU2006202213A1 (en) | 2000-04-07 | 2006-05-25 | Bile acid containing prodrugs with enhanced bioavailability |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP1267898A4 (en) |
JP (1) | JP2003530329A (en) |
AU (3) | AU5322601A (en) |
CA (1) | CA2405151A1 (en) |
WO (1) | WO2001076531A2 (en) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7144877B2 (en) | 2000-10-06 | 2006-12-05 | Xenoport, Inc. | Bile-acid derived compounds for enhancing oral absorption and systemic bioavailability of drugs |
AU2002211863A1 (en) * | 2000-10-06 | 2002-04-15 | Xenoport, Inc. | Bile-acid derived compounds for providing sustained systemic concentrations of drugs after oral administration |
US6900192B2 (en) | 2000-10-06 | 2005-05-31 | Xenoport, Inc. | Bile-acid conjugates for providing sustained systemic concentrations of drugs |
WO2004062574A2 (en) | 2003-01-13 | 2004-07-29 | Bracco Imaging S.P.A. | Improved linkers for radiopharmaceutical compounds |
AU2004322123B2 (en) * | 2004-08-02 | 2009-08-13 | Ambrilia Biopharma Inc. | Lysine based compounds |
EP2001897A2 (en) * | 2006-03-22 | 2008-12-17 | Syndexa Pharmaceuticals Corporation | Compounds and methods for treatment of disorders associated with er stress |
JP5201546B2 (en) * | 2008-01-18 | 2013-06-05 | 学校法人近畿大学 | N-acetylcysteine-conjugated bile acid, pharmaceutical composition containing the same and method for producing the same |
CA2966422C (en) | 2014-10-31 | 2022-06-28 | University Of Utah Research Foundation | Compositions and methods for bile acid particles |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9212511D0 (en) * | 1992-06-12 | 1992-07-22 | Cortecs Ltd | Pharmaceutical compositions |
AUPO912997A0 (en) * | 1997-09-11 | 1997-10-02 | Commonwealth Scientific And Industrial Research Organisation | Antiviral agents |
GB9907048D0 (en) * | 1999-03-27 | 1999-05-19 | Karobio Ab | Novel glucocorticoid receptor ligands for the treatment of meta bolic disorders |
AU7703400A (en) * | 1999-09-14 | 2001-04-17 | Xenoport, Inc. | Substrates and screening methods for transport proteins |
-
2001
- 2001-04-06 JP JP2001574050A patent/JP2003530329A/en not_active Withdrawn
- 2001-04-06 WO PCT/US2001/011327 patent/WO2001076531A2/en active Application Filing
- 2001-04-06 EP EP01926709A patent/EP1267898A4/en not_active Ceased
- 2001-04-06 CA CA002405151A patent/CA2405151A1/en not_active Abandoned
- 2001-04-06 AU AU5322601A patent/AU5322601A/en active Pending
- 2001-04-06 AU AU2001253226A patent/AU2001253226B2/en not_active Ceased
-
2006
- 2006-05-25 AU AU2006202213A patent/AU2006202213A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
AU2001253226B2 (en) | 2006-06-08 |
AU2006202213A1 (en) | 2006-06-15 |
JP2003530329A (en) | 2003-10-14 |
CA2405151A1 (en) | 2001-10-18 |
EP1267898A4 (en) | 2006-02-01 |
EP1267898A2 (en) | 2003-01-02 |
WO2001076531A3 (en) | 2002-02-14 |
WO2001076531A2 (en) | 2001-10-18 |
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