AU4209493A - Benzimidazoles - Google Patents

Benzimidazoles

Info

Publication number
AU4209493A
AU4209493A AU42094/93A AU4209493A AU4209493A AU 4209493 A AU4209493 A AU 4209493A AU 42094/93 A AU42094/93 A AU 42094/93A AU 4209493 A AU4209493 A AU 4209493A AU 4209493 A AU4209493 A AU 4209493A
Authority
AU
Australia
Prior art keywords
benzimidazoles
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
AU42094/93A
Other versions
AU675433B2 (en
Inventor
Michael Entzeroth
Norbert Hauel
Uwe Ries
Jacques Van Meel
Wolfgang Wienen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim Pharma GmbH and Co KG
Original Assignee
Dr Karl Thomae GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dr Karl Thomae GmbH filed Critical Dr Karl Thomae GmbH
Publication of AU4209493A publication Critical patent/AU4209493A/en
Application granted granted Critical
Publication of AU675433B2 publication Critical patent/AU675433B2/en
Anticipated expiration legal-status Critical
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D235/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/06Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
    • C07D235/08Radicals containing only hydrogen and carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D235/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/24Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/06Antiglaucoma agents or miotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
AU42094/93A 1991-02-06 1993-07-21 Benzimidazoles Expired AU675433B2 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
DE4103492 1991-02-06
DE4117121 1991-05-25
DE4137812 1991-11-16
DE4224133A DE4224133A1 (en) 1992-07-22 1992-07-22 Benzimidazoles, medicaments containing these compounds and process for their preparation
DE4224133 1992-07-22

Related Parent Applications (2)

Application Number Title Priority Date Filing Date
AU10707/92A Division AU655794C (en) 1991-02-06 1992-02-05 Benzimidazole compounds
AU10707/92A Addition AU655794C (en) 1991-02-06 1992-02-05 Benzimidazole compounds

Publications (2)

Publication Number Publication Date
AU4209493A true AU4209493A (en) 1994-01-27
AU675433B2 AU675433B2 (en) 1997-02-06

Family

ID=6463804

Family Applications (1)

Application Number Title Priority Date Filing Date
AU42094/93A Expired AU675433B2 (en) 1991-02-06 1993-07-21 Benzimidazoles

Country Status (20)

Country Link
EP (1) EP0581166A1 (en)
JP (1) JPH06179659A (en)
KR (1) KR940005584A (en)
CN (1) CN1050122C (en)
AU (1) AU675433B2 (en)
CA (1) CA2100927A1 (en)
CZ (1) CZ144993A3 (en)
DE (1) DE4224133A1 (en)
FI (1) FI933284A (en)
HU (1) HUT64955A (en)
IL (1) IL106408A (en)
MX (1) MX9304424A (en)
NO (1) NO300772B1 (en)
NZ (1) NZ248217A (en)
PL (1) PL172929B1 (en)
RU (1) RU2126401C1 (en)
SG (1) SG43083A1 (en)
SK (1) SK73293A3 (en)
TW (1) TW229207B (en)
ZA (1) ZA93529B (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU669736B2 (en) * 1992-10-06 1996-06-20 Dr. Karl Thomae Gmbh Benzimidazoles
AU672262B2 (en) * 1993-02-15 1996-09-26 Bayer Aktiengesellschaft Heterocyclically substituted phenyl-cyclohexane-carboxylic acid derivatives

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4324580A1 (en) * 1993-07-22 1995-01-26 Thomae Gmbh Dr K Bicyclic heterocycles, pharmaceutical compositions containing them and methods for their preparation
EP0882718B1 (en) * 1995-12-28 2005-08-31 Fujisawa Pharmaceutical Co., Ltd. Benzimidazole derivatives
TW453999B (en) * 1997-06-27 2001-09-11 Fujisawa Pharmaceutical Co Benzimidazole derivatives
HU222773B1 (en) * 2000-04-21 2003-10-28 Richter Gedeon Vegyészeti Gyár Rt. Process for producing a known tetrazole derivative
WO2005011736A1 (en) * 2003-07-30 2005-02-10 Tohoku Techno Arch Co., Ltd. Drug for preventing and/or treating alzheimer’s disease
CN101891735B (en) * 2009-11-25 2012-07-18 北京理工大学 Biphenyl sulfafurazole compound, synthesis method and application thereof
CN101921265B (en) * 2009-11-25 2012-07-04 北京理工大学 Biphenylacylamine tetrazole compounds, synthetic method and application
ES2552514T3 (en) * 2011-11-03 2015-11-30 Hoffmann-La Roche Ag Bicyclic Piperazine Compounds
CN105820125B (en) * 2015-01-09 2018-12-07 北京中医药大学 A kind of compound and its preparation method and application for treating hypertension
CN105384729B (en) * 2015-07-09 2019-02-19 天津青松华药医药有限公司 Telmisartan ester derivative and the preparation method and application thereof
CN106749220B (en) * 2017-01-18 2019-08-06 东华大学 6 '-substituted benzimidazole -4- substituent methyl indole derivatives of one kind and its preparation and application

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3928177A1 (en) * 1989-04-08 1991-02-28 Thomae Gmbh Dr K BENZIMIDAZOLE, MEDICAMENTS CONTAINING THESE COMPOUNDS AND METHOD FOR THE PRODUCTION THEREOF
RU1836357C (en) * 1990-07-23 1993-08-23 Др.Карл Томэ ГмбХ Benzimidazole derivatives, their isomers, mixtures of isomers, hydrates or their physiologically bearable salts possessing properties antagonistic to angiotenzine
SI9210098B (en) * 1991-02-06 2000-06-30 Dr. Karl Thomae Benzimidazoles, drugs with this compounds, and process for their preparation
DE4237656A1 (en) * 1992-06-13 1993-12-16 Merck Patent Gmbh benzimidazole derivatives

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU669736B2 (en) * 1992-10-06 1996-06-20 Dr. Karl Thomae Gmbh Benzimidazoles
AU672262B2 (en) * 1993-02-15 1996-09-26 Bayer Aktiengesellschaft Heterocyclically substituted phenyl-cyclohexane-carboxylic acid derivatives

Also Published As

Publication number Publication date
CN1050122C (en) 2000-03-08
AU675433B2 (en) 1997-02-06
FI933284A (en) 1994-01-23
NO932636D0 (en) 1993-07-21
CN1083812A (en) 1994-03-16
NZ248217A (en) 1996-06-25
NO932636L (en) 1994-01-24
SG43083A1 (en) 1997-10-17
CZ144993A3 (en) 1994-03-16
NO300772B1 (en) 1997-07-21
EP0581166A1 (en) 1994-02-02
HUT64955A (en) 1994-03-28
HU9302115D0 (en) 1993-10-28
FI933284A0 (en) 1993-07-21
PL299754A1 (en) 1994-03-21
IL106408A0 (en) 1993-11-15
TW229207B (en) 1994-09-01
KR940005584A (en) 1994-03-21
IL106408A (en) 1998-08-16
MX9304424A (en) 1994-01-31
DE4224133A1 (en) 1994-01-27
CA2100927A1 (en) 1994-01-23
RU2126401C1 (en) 1999-02-20
JPH06179659A (en) 1994-06-28
ZA93529B (en) 1995-01-23
SK73293A3 (en) 1994-04-06
PL172929B1 (en) 1997-12-31

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Legal Events

Date Code Title Description
NCW Application for extension of term withdrawn (under section 73 patents act 1990)

Free format text: PRODUCT NAME: MICARDIS TELMISARTAN