AU2957997A - 1,2,4-oxadiazoles as adhesion-receptor antagonists - Google Patents
1,2,4-oxadiazoles as adhesion-receptor antagonistsInfo
- Publication number
- AU2957997A AU2957997A AU29579/97A AU2957997A AU2957997A AU 2957997 A AU2957997 A AU 2957997A AU 29579/97 A AU29579/97 A AU 29579/97A AU 2957997 A AU2957997 A AU 2957997A AU 2957997 A AU2957997 A AU 2957997A
- Authority
- AU
- Australia
- Prior art keywords
- oxadiazoles
- adhesion
- receptor antagonists
- antagonists
- receptor
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19620041A DE19620041A1 (en) | 1996-05-17 | 1996-05-17 | Adhesion receptor antagonists |
| DE19620041 | 1996-05-17 | ||
| PCT/EP1997/002555 WO1997044333A1 (en) | 1996-05-17 | 1997-05-20 | 1,2,4-oxadiazoles as adhesion-receptor antagonists |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AU2957997A true AU2957997A (en) | 1997-12-09 |
Family
ID=7794651
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU29579/97A Abandoned AU2957997A (en) | 1996-05-17 | 1997-05-20 | 1,2,4-oxadiazoles as adhesion-receptor antagonists |
Country Status (5)
| Country | Link |
|---|---|
| AR (1) | AR007160A1 (en) |
| AU (1) | AU2957997A (en) |
| DE (1) | DE19620041A1 (en) |
| WO (1) | WO1997044333A1 (en) |
| ZA (1) | ZA974234B (en) |
Families Citing this family (45)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0928194A4 (en) * | 1996-08-29 | 2001-01-17 | Merck & Co Inc | Compositions and methods for administering integrin receptor antagonists |
| WO1999038829A1 (en) | 1998-01-28 | 1999-08-05 | Shionogi & Co., Ltd. | Novel tricyclic compound |
| GB9805655D0 (en) | 1998-03-16 | 1998-05-13 | Celltech Therapeutics Ltd | Chemical compounds |
| US6521626B1 (en) | 1998-03-24 | 2003-02-18 | Celltech R&D Limited | Thiocarboxamide derivatives |
| WO1999050249A2 (en) * | 1998-04-01 | 1999-10-07 | Du Pont Pharmaceuticals Company | Pyrimidines and triazines as integrin antagonists |
| GB9814414D0 (en) | 1998-07-03 | 1998-09-02 | Celltech Therapeutics Ltd | Chemical compounds |
| EP1100506A4 (en) * | 1998-07-29 | 2002-06-26 | Merck & Co Inc | Integrin receptor antagonists |
| GB9821061D0 (en) | 1998-09-28 | 1998-11-18 | Celltech Therapeutics Ltd | Chemical compounds |
| US6107313A (en) * | 1998-10-02 | 2000-08-22 | Combichem, Inc. | Dopamine receptor antagonists |
| GB9826174D0 (en) | 1998-11-30 | 1999-01-20 | Celltech Therapeutics Ltd | Chemical compounds |
| US6518283B1 (en) | 1999-05-28 | 2003-02-11 | Celltech R&D Limited | Squaric acid derivatives |
| US6534513B1 (en) | 1999-09-29 | 2003-03-18 | Celltech R&D Limited | Phenylalkanoic acid derivatives |
| US6455539B2 (en) | 1999-12-23 | 2002-09-24 | Celltech R&D Limited | Squaric acid derivates |
| AU2001248553A1 (en) | 2000-04-17 | 2001-10-30 | Celltech R And D Limited | Enamine derivatives as cell adhesion molecules |
| US6545013B2 (en) | 2000-05-30 | 2003-04-08 | Celltech R&D Limited | 2,7-naphthyridine derivatives |
| US6403608B1 (en) | 2000-05-30 | 2002-06-11 | Celltech R&D, Ltd. | 3-Substituted isoquinolin-1-yl derivatives |
| US6933304B2 (en) | 2000-06-15 | 2005-08-23 | Pharmacia Corporation | Heteroarylalkanoic acids as integrin receptor antagonists |
| AU2001267753A1 (en) | 2000-07-07 | 2002-01-21 | Celltech R And D Limited | Squaric acid derivatives containing a bicyclic heteroaromatic ring as integrin antagonists |
| WO2002010136A1 (en) | 2000-08-02 | 2002-02-07 | Celltech R & D Limited | 3-substituted isoquinolin-1-yl derivatives |
| US20030105144A1 (en) | 2001-04-17 | 2003-06-05 | Ping Gao | Stabilized oral pharmaceutical composition |
| IL159086A0 (en) * | 2001-06-08 | 2004-05-12 | Cytovia Inc | 3-aryl-5-aryl- [1, 2, 4] -oxadiazole derivatives and pharmaceutical compositions containing the same |
| CA2488117A1 (en) | 2002-06-17 | 2003-12-24 | Merck & Co., Inc. | 1-((5-aryl-1,2,4-oxadiazol-3-yl)benzyl)azetidine-3-carboxylates and 1-((5-aryl-1,2,4-oxadiazol-3-yl)benzyl)pyrrolidine-3-carboxylates as edg receptor agonists |
| JP2006518333A (en) * | 2002-12-20 | 2006-08-10 | ファルマシア・コーポレーション | Heteroarylalkanoic acids as integrin receptor antagonists |
| US7115596B2 (en) | 2002-12-20 | 2006-10-03 | Pharmacia Corporation | Thiazole compounds as integrin receptor antagonists derivatives |
| GB0303503D0 (en) * | 2003-02-14 | 2003-03-19 | Novartis Ag | Organic compounds |
| ES2926542T3 (en) * | 2003-04-11 | 2022-10-26 | Ptc Therapeutics Inc | 1,2,4-oxadiazole benzoic acid compounds and their use for suppression of nonsense mutations and treatment of diseases |
| EP1697333A4 (en) | 2003-12-17 | 2009-07-08 | Merck & Co Inc | (3,4-disubstituted)propanoic carboxylates as s1p (edg) receptor agonists |
| EP1799212A2 (en) | 2004-10-13 | 2007-06-27 | PTC Therapeutics, Inc. | Compounds for nonsense suppression, and methods for their use |
| BRPI0612028A2 (en) * | 2005-06-08 | 2010-10-13 | Novartis Ag | polycyclic oxadiazoles or isodiazoles and their use as s1p receptor ligands |
| US20090325924A1 (en) * | 2005-06-30 | 2009-12-31 | Stuart Edward | GPCR Agonists |
| SG170819A1 (en) | 2006-03-30 | 2011-05-30 | Ptc Therapeutics Inc | Methods for the production of functional protein from dna having a nonsense mutation and the treatment of disorders associated therewith |
| DK3357911T3 (en) | 2006-06-26 | 2022-07-04 | Akebia Therapeutics Inc | PROLYLHYDROXYLASE INHIBITORS AND METHODS OF USE |
| JO2701B1 (en) | 2006-12-21 | 2013-03-03 | جلاكسو جروب ليميتد | Compounds |
| BRPI0914629A2 (en) * | 2008-06-24 | 2019-09-24 | Irm Llc | compounds and methods for modulating g protein-coupled receptors |
| NO2686520T3 (en) | 2011-06-06 | 2018-03-17 | ||
| US20120329836A1 (en) | 2011-06-06 | 2012-12-27 | The Ohio State University | Methods for stabilizing hypoxia inducible factor-2 alpha as a method for treating cancer |
| US11857543B2 (en) | 2013-06-13 | 2024-01-02 | Akebia Therapeutics, Inc. | Compositions and methods for treating anemia |
| CR20200220A (en) | 2013-11-15 | 2020-11-18 | Akebia Therapeutics Inc | Solid forms of {[5-(3-chlorophenyl)-3-hydroxypyridine-2-carbonyl]amino}acetic acid, compositions, and uses thereof |
| CA3174516A1 (en) | 2014-03-06 | 2015-09-11 | Ptc Therapeutics, Inc. | Pharmaceutical compositions and salts of a 1,2,4-oxadiazole benzoic acid |
| JP2018502882A (en) | 2015-01-23 | 2018-02-01 | アケビア セラピューティクス インコーポレイテッドＡｋｅｂｉａ Ｔｈｅｒａｐｅｕｔｉｃｓ Ｉｎｃ． | Solid form of 2- (5- (3-fluorophenyl) -3-hydroxypicolinamide) acetic acid, its composition and use |
| MX2017012460A (en) | 2015-04-01 | 2018-01-30 | Akebia Therapeutics Inc | Compositions and methods for treating anemia. |
| MX2018005361A (en) | 2015-10-30 | 2018-06-07 | Ptc Therapeutics Inc | Methods for treating epilepsy. |
| TWI822776B (en) | 2018-05-09 | 2023-11-21 | 美商阿克比治療有限公司 | Process for preparing 2-[[5-(3-chlorophenyl)-3-hydroxypyridine-2-carbonyl]amino]acetic acid |
| US11524939B2 (en) | 2019-11-13 | 2022-12-13 | Akebia Therapeutics, Inc. | Solid forms of {[5-(3-chlorophenyl)-3-hydroxypyridine-2-carbonyl]amino} acetic acid |
| GB202209228D0 (en) * | 2022-06-23 | 2022-08-10 | Univ Strathclyde | Modified amino acids and uses thereof |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB935523A (en) * | 1961-06-17 | 1963-08-28 | Acraf | New sulphamido-oxadiazoles |
| JPS51143669A (en) * | 1975-06-06 | 1976-12-10 | Takeda Chem Ind Ltd | A process for preparing 1,2,4- oxadiazole derivatives |
| JPS52272A (en) * | 1975-10-17 | 1977-01-05 | Takeda Chem Ind Ltd | Process for preparing 1,2,4-oxadiazole derivatives |
| US4135910A (en) * | 1977-05-12 | 1979-01-23 | Monsanto Company | Oxadiazol-3-yl-benzoates as plant growth regulants |
| WO1994022846A1 (en) * | 1993-03-30 | 1994-10-13 | Pfizer Inc. | Compounds enhancing antitumor activity of other cytotoxic agents |
-
1996
- 1996-05-17 DE DE19620041A patent/DE19620041A1/en not_active Withdrawn
-
1997
- 1997-05-15 ZA ZA9704234A patent/ZA974234B/en unknown
- 1997-05-16 AR ARP970102054A patent/AR007160A1/en unknown
- 1997-05-20 WO PCT/EP1997/002555 patent/WO1997044333A1/en active Application Filing
- 1997-05-20 AU AU29579/97A patent/AU2957997A/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| DE19620041A1 (en) | 1998-01-29 |
| ZA974234B (en) | 1997-12-11 |
| WO1997044333A1 (en) | 1997-11-27 |
| AR007160A1 (en) | 1999-10-13 |
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