AU2554897A - Inhibitors of farnesyl-protein transferase - Google Patents
Inhibitors of farnesyl-protein transferaseInfo
- Publication number
- AU2554897A AU2554897A AU25548/97A AU2554897A AU2554897A AU 2554897 A AU2554897 A AU 2554897A AU 25548/97 A AU25548/97 A AU 25548/97A AU 2554897 A AU2554897 A AU 2554897A AU 2554897 A AU2554897 A AU 2554897A
- Authority
- AU
- Australia
- Prior art keywords
- farnesyl
- inhibitors
- protein transferase
- transferase
- protein
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Urology & Nephrology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Cardiology (AREA)
- Virology (AREA)
- Ophthalmology & Optometry (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US1459396P | 1996-04-03 | 1996-04-03 | |
US60/014593 | 1996-04-03 | ||
GBGB9613460.6A GB9613460D0 (en) | 1996-06-27 | 1996-06-27 | Inhibitors of farnesyl-protein transferase |
GB9613460 | 1996-06-27 | ||
PCT/US1997/005144 WO1997036593A1 (en) | 1996-04-03 | 1997-03-27 | Inhibitors of farnesyl-protein transferase |
Publications (2)
Publication Number | Publication Date |
---|---|
AU2554897A true AU2554897A (en) | 1997-10-22 |
AU706495B2 AU706495B2 (en) | 1999-06-17 |
Family
ID=26309575
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU25548/97A Ceased AU706495B2 (en) | 1996-04-03 | 1997-03-27 | Inhibitors of farnesyl-protein transferase |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP0921801A1 (en) |
JP (1) | JP2000507582A (en) |
AU (1) | AU706495B2 (en) |
CA (1) | CA2249599A1 (en) |
WO (1) | WO1997036593A1 (en) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6387903B1 (en) | 1997-08-27 | 2002-05-14 | Merck & Co., Inc. | Inhibitors of prenyl-protein transferase |
WO1999009985A1 (en) * | 1997-08-27 | 1999-03-04 | Merck & Co., Inc. | Inhibitors of prenyl-protein transferase |
WO1999065494A1 (en) * | 1998-06-15 | 1999-12-23 | Merck & Co., Inc. | Inhibitors of prenyl-protein transferase |
AU754554B2 (en) | 1998-07-02 | 2002-11-21 | Merck & Co., Inc. | Inhibitors of prenyl-protein transferase |
CA2363169A1 (en) | 1999-03-03 | 2000-09-08 | Merck & Co., Inc. | Inhibitors of prenyl-protein transferase |
WO2000051612A1 (en) | 1999-03-03 | 2000-09-08 | Merck & Co., Inc. | Inhibitors of prenyl-protein transferase |
US6335343B1 (en) | 1999-03-03 | 2002-01-01 | Merck & Co., Inc. | Inhibitors of prenyl-protein transferase |
USRE39921E1 (en) | 1999-10-07 | 2007-11-13 | Smithkline Beecham Corporation | Chemical compounds |
GB9923748D0 (en) * | 1999-10-07 | 1999-12-08 | Glaxo Group Ltd | Chemical compounds |
GB0025354D0 (en) | 2000-10-17 | 2000-11-29 | Glaxo Group Ltd | Chemical compounds |
GB0203020D0 (en) | 2002-02-08 | 2002-03-27 | Glaxo Group Ltd | Chemical compounds |
JP2005522436A (en) | 2002-02-08 | 2005-07-28 | グラクソ グループ リミテッド | Piperidylcarboxamide derivatives or their use in the treatment of tachykinin-mediated diseases |
GB0203022D0 (en) | 2002-02-08 | 2002-03-27 | Glaxo Group Ltd | Chemical compounds |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3915981A (en) * | 1973-03-16 | 1975-10-28 | Yoshitomi Pharmaceutical | 1-{8 2-(2-Chlorobenzoyl)-4-nitrophenyl{9 -2-(diethylaminomethyl)-imidazole |
US5138069A (en) * | 1986-07-11 | 1992-08-11 | E. I. Du Pont De Nemours And Company | Angiotensin II receptor blocking imidazoles |
US4835154A (en) * | 1987-06-01 | 1989-05-30 | Smithkline Beckman Corporation | 1-aralykyl-5-piperazinylmethyl-2-mercaptoimidazoles and 2-alkylthioimidazoles and their use as dopamine-βhydroxylase inhibitors |
US5219856A (en) * | 1992-04-06 | 1993-06-15 | E. I. Du Pont De Nemours And Company | Angiotensin-II receptor blocking, heterocycle substituted imidazoles |
US5478934A (en) * | 1994-11-23 | 1995-12-26 | Yuan; Jun | Certain 1-substituted aminomethyl imidazole and pyrrole derivatives: novel dopamine receptor subtype specific ligands |
WO1996016057A1 (en) * | 1994-11-23 | 1996-05-30 | Neurogen Corporation | Certain 1-substituted aminomethyl imidazole and pyrrole derivatives; novel dopamine receptor subtype specific ligands |
-
1997
- 1997-03-27 AU AU25548/97A patent/AU706495B2/en not_active Ceased
- 1997-03-27 EP EP97917116A patent/EP0921801A1/en not_active Withdrawn
- 1997-03-27 JP JP9535473A patent/JP2000507582A/en active Pending
- 1997-03-27 WO PCT/US1997/005144 patent/WO1997036593A1/en not_active Application Discontinuation
- 1997-03-27 CA CA002249599A patent/CA2249599A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
AU706495B2 (en) | 1999-06-17 |
EP0921801A1 (en) | 1999-06-16 |
WO1997036593A1 (en) | 1997-10-09 |
JP2000507582A (en) | 2000-06-20 |
CA2249599A1 (en) | 1997-10-09 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
AU703203B2 (en) | Inhibitors of farnesyl-protein transferase | |
AU2734797A (en) | Inhibitors of farnesyl-protein transferase | |
AU2670297A (en) | Inhibitors of farnesyl-protein transferase | |
AU2593097A (en) | Inhibitors of farnesyl-protein transferase | |
AU2253097A (en) | Inhibitors of farnesyl-protein transferase | |
AU2430197A (en) | Inhibitors of farnesyl-protein transferase | |
AU1988495A (en) | Inhibitors of farnesyl-protein transferase | |
AU2555997A (en) | Inhibitors of farnesyl-protein transferase | |
AU3373195A (en) | Inhibitors of farnesyl-protein transferase | |
AU2598897A (en) | Inhibitors of farnesyl-protein transferase | |
AU2605897A (en) | Inhibitors of farnesyl-protein transferase | |
GB9604311D0 (en) | Inhibitors of farnesyl-protein transferase | |
AU2552497A (en) | Inhibitors of farnesyl-protein transferase | |
AU2605797A (en) | Inhibitors of farnesyl-protein transferase | |
AU1851697A (en) | Inhibitors of farnesyl-protein transferase | |
AU2587597A (en) | Inhibitors of farnesyl-protein transferase | |
AU2432597A (en) | Inhibitors of farnesyl-protein transferase | |
AU2432697A (en) | Inhibitors of farnesyl-protein transferase | |
AU2430397A (en) | Inhibitors of farnesyl-protein transferase | |
AU2554897A (en) | Inhibitors of farnesyl-protein transferase | |
EP0891352A4 (en) | Inhibitors of farnesyl-protein transferase | |
AU2600597A (en) | Inhibitors of farnesyl-protein transferase | |
AU2602097A (en) | Inhibitors of farnesyl-protein transferase | |
AU2593297A (en) | Inhibitors of farnesyl-protein transferase | |
AU1952697A (en) | Inhibitors of farnesyl-protein transferase |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
MK14 | Patent ceased section 143(a) (annual fees not paid) or expired |