AU2084492A - Process for increasing the enantioselectivity of a candida lipase in the esterification of chiral alcohols, and an immobilized candida lipase - Google Patents

Process for increasing the enantioselectivity of a candida lipase in the esterification of chiral alcohols, and an immobilized candida lipase

Info

Publication number
AU2084492A
AU2084492A AU20844/92A AU2084492A AU2084492A AU 2084492 A AU2084492 A AU 2084492A AU 20844/92 A AU20844/92 A AU 20844/92A AU 2084492 A AU2084492 A AU 2084492A AU 2084492 A AU2084492 A AU 2084492A
Authority
AU
Australia
Prior art keywords
candida lipase
enantioselectivity
esterification
increasing
immobilized
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
AU20844/92A
Other versions
AU649347B2 (en
Inventor
Brigitte Berger
Kurt Faber
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Chemie Linz GmbH
Original Assignee
Chemie Linz GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chemie Linz GmbH filed Critical Chemie Linz GmbH
Publication of AU2084492A publication Critical patent/AU2084492A/en
Application granted granted Critical
Publication of AU649347B2 publication Critical patent/AU649347B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • C12N11/02Enzymes or microbial cells immobilised on or in an organic carrier
    • C12N11/08Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer
    • C12N11/082Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer obtained by reactions only involving carbon-to-carbon unsaturated bonds
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/16Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/18Carboxylic ester hydrolases (3.1.1)
    • C12N9/20Triglyceride splitting, e.g. by means of lipase
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/14Fungi; Culture media therefor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • C12N11/02Enzymes or microbial cells immobilised on or in an organic carrier
    • C12N11/04Enzymes or microbial cells immobilised on or in an organic carrier entrapped within the carrier, e.g. gel or hollow fibres
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P41/00Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
    • C12P41/003Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions
    • C12P41/004Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions by esterification of alcohol- or thiol groups in the enantiomers or the inverse reaction

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Analytical Chemistry (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Botany (AREA)
  • Mycology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Enzymes And Modification Thereof (AREA)
AU20844/92A 1991-08-30 1992-08-05 Process for increasing the enantioselectivity of a candida lipase in the esterification of chiral alcohols, and an immobilized candida lipase Ceased AU649347B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
AT1715/91 1991-08-30
AT0171591A AT398310B (en) 1991-08-30 1991-08-30 IMMOBILIZED LIPASE, METHOD FOR THE PRODUCTION THEREOF AND METHOD FOR INCREASING THE ENANTIOSELECTIVITY OF A CANDIDA LIPASE IN THE Esterification of CHIRAL ALCOHOLS

Publications (2)

Publication Number Publication Date
AU2084492A true AU2084492A (en) 1993-03-04
AU649347B2 AU649347B2 (en) 1994-05-19

Family

ID=3519425

Family Applications (1)

Application Number Title Priority Date Filing Date
AU20844/92A Ceased AU649347B2 (en) 1991-08-30 1992-08-05 Process for increasing the enantioselectivity of a candida lipase in the esterification of chiral alcohols, and an immobilized candida lipase

Country Status (13)

Country Link
EP (1) EP0529424A3 (en)
JP (1) JPH05207881A (en)
KR (1) KR930004462A (en)
AT (1) AT398310B (en)
AU (1) AU649347B2 (en)
CA (1) CA2075699A1 (en)
CZ (1) CZ252792A3 (en)
HU (1) HUT63658A (en)
NZ (1) NZ243708A (en)
SI (1) SI9200192A (en)
SK (1) SK252792A3 (en)
YU (1) YU76692A (en)
ZA (1) ZA926022B (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3431204B2 (en) * 1993-04-22 2003-07-28 塩野義製薬株式会社 Norbornane type ester hydrolase
EP0893422A1 (en) * 1997-07-18 1999-01-27 Mitsubishi Gas Chemical Company, Inc. Optically active alcohol and process for the production thereof
IL152290A0 (en) * 2002-10-14 2003-05-29 Enzymotec Ltd Immobilization of compounds on polymeric matrix
ITMI20070435A1 (en) 2007-03-05 2008-09-06 Innovate Biotechnology Srl 2 ', 3'-DI-O-acyl-5-FLUORONUCLEOSIDI

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3743824C2 (en) * 1987-12-23 1997-03-06 Hoechst Ag Process for the enzymatic resolution of racemic alcohols with / in vinyl esters by transesterification
DE3819467A1 (en) * 1988-06-08 1989-12-14 Basf Ag METHOD FOR PRODUCING A BIO CATALYST AND ITS USE FOR RAZEMATE CUTTING
US5108916A (en) * 1989-06-05 1992-04-28 Rhone-Poulenc Rorer, S.A. Process for stereoselectively hydrolyzing, transesterifying or esterifying with immobilized isozyme of lipase from candida rugosa
JPH03183480A (en) * 1989-12-13 1991-08-09 Ajinomoto Co Inc Immobilized lipase and ester exchange reaction of fat or oil with the same
DE4131546A1 (en) * 1991-09-21 1993-03-25 Chemie Linz Deutschland Candida lipase for high activity and aldehyde resistance - comprises covalent bonding to epoxy activated macroporous carrier for immobilisation and enantioselective esterification of chiral alcohol with enol ester

Also Published As

Publication number Publication date
AU649347B2 (en) 1994-05-19
CA2075699A1 (en) 1993-03-01
ATA171591A (en) 1994-03-15
SI9200192A (en) 1993-03-31
YU76692A (en) 1995-03-27
KR930004462A (en) 1993-03-22
ZA926022B (en) 1993-03-10
HU9202785D0 (en) 1992-12-28
EP0529424A3 (en) 1993-11-10
NZ243708A (en) 1993-10-26
AT398310B (en) 1994-11-25
EP0529424A2 (en) 1993-03-03
SK252792A3 (en) 1995-11-08
CZ252792A3 (en) 1993-03-17
JPH05207881A (en) 1993-08-20
HUT63658A (en) 1993-09-28

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