AU2003219947A1 - Compositions and methods for hydroxylating epothilones - Google Patents

Compositions and methods for hydroxylating epothilones

Info

Publication number
AU2003219947A1
AU2003219947A1 AU2003219947A AU2003219947A AU2003219947A1 AU 2003219947 A1 AU2003219947 A1 AU 2003219947A1 AU 2003219947 A AU2003219947 A AU 2003219947A AU 2003219947 A AU2003219947 A AU 2003219947A AU 2003219947 A1 AU2003219947 A1 AU 2003219947A1
Authority
AU
Australia
Prior art keywords
hydroxylating
epothilones
compositions
methods
hydroxylating epothilones
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2003219947A
Inventor
Jonathan David Basch
Shu-Jen Chiang
Suo-Win Liu
Akbar Nayeem
Yuhua Sun
Li You
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bristol Myers Squibb Co
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Publication of AU2003219947A1 publication Critical patent/AU2003219947A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0071—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)
    • C12N9/0077—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14) with a reduced iron-sulfur protein as one donor (1.14.15)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/18—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
    • C12P17/181—Heterocyclic compounds containing oxygen atoms as the only ring heteroatoms in the condensed system, e.g. Salinomycin, Septamycin
AU2003219947A 2003-02-26 2003-02-26 Compositions and methods for hydroxylating epothilones Abandoned AU2003219947A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US2003/006108 WO2004078978A1 (en) 2003-02-26 2003-02-26 Compositions and methods for hydroxylating epothilones

Publications (1)

Publication Number Publication Date
AU2003219947A1 true AU2003219947A1 (en) 2004-09-28

Family

ID=32961093

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2003219947A Abandoned AU2003219947A1 (en) 2003-02-26 2003-02-26 Compositions and methods for hydroxylating epothilones

Country Status (2)

Country Link
AU (1) AU2003219947A1 (en)
WO (1) WO2004078978A1 (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7649006B2 (en) 2002-08-23 2010-01-19 Sloan-Kettering Institute For Cancer Research Synthesis of epothilones, intermediates thereto and analogues thereof
JP4791183B2 (en) 2002-08-23 2011-10-12 スローン−ケッタリング インスティトュート フォア キャンサー リサーチ Synthesis and use of epothilone, its intermediates and analogues
DK2094841T3 (en) * 2006-12-13 2012-05-29 Dsm Sinochem Pharm Nl Bv Process for the preparation of pravastatin
AU2011255647A1 (en) 2010-05-18 2012-11-15 Cerulean Pharma Inc. Compositions and methods for treatment of autoimmune and other diseases
US11384371B2 (en) 2016-11-15 2022-07-12 Hypha Discovery Limited Hydroxylation of branched aliphatic or aromatic substrates employing the amycolatopsis lurida cytochrome P450
GB201807815D0 (en) * 2018-05-14 2018-06-27 Hypha Discovery Ltd Hydroxylation techniques
GB201819209D0 (en) 2018-11-26 2019-01-09 Hypha Discovery Ltd Biocatalytic techniques

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6211412B1 (en) * 1999-03-29 2001-04-03 The University Of Kansas Synthesis of epothilones
US6294374B1 (en) * 1999-10-08 2001-09-25 The Scripps Research Institute Use of catalytic antibodies for synthesizing epothilone

Also Published As

Publication number Publication date
WO2004078978A1 (en) 2004-09-16

Similar Documents

Publication Publication Date Title
AU2003248862A1 (en) Compositions and fabrication methods for hardmetals
AU2003226094A1 (en) Compounds and methods
AU2003285288A1 (en) Composition
AU2003256805A1 (en) Compounds compositions and methods
AU2002950744A0 (en) Composition
AU2003291443A1 (en) Compositions and processes for nanoimprinting
EP1572991A4 (en) Compositions and methods for hydroxilating epothilones
AU2003235708A1 (en) Polytartrate composition
AU2003272864A1 (en) Composition for treting hyperlipemia
AU2003208411A1 (en) Anti-glycolytic composition
AU2003219947A1 (en) Compositions and methods for hydroxylating epothilones
AU2003232732A1 (en) Transformer
EP1465908A4 (en) Compositions and methods for hydroxylating epothilones
AU2003100144A4 (en) Lousicide composition
AU2003268772A1 (en) Oil-barrier composition
AU2003284506A1 (en) Coolant composition
AU2003238680A1 (en) Novel dithioketal
AU2003304593A1 (en) Coolant composition
AU2003231740A1 (en) Compositions and methods for diagnostics and therapeutics for hydrocephalus
AU2003906800A0 (en) Composition and Methods
AU2003903850A0 (en) Anti-coronavirus compounds and methods
AU2003907066A0 (en) Compounds and Methods
AU2003223357A1 (en) Compounds and methods
AU2003900691A0 (en) Compounds and Uses Therefor
AU2003218460A1 (en) Compositions and methods for immunomodulation

Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase