AU2003217369A1 - Method and apparatus for performing submicroliter reactions with nucleic acids or proteins - Google Patents

Method and apparatus for performing submicroliter reactions with nucleic acids or proteins

Info

Publication number
AU2003217369A1
AU2003217369A1 AU2003217369A AU2003217369A AU2003217369A1 AU 2003217369 A1 AU2003217369 A1 AU 2003217369A1 AU 2003217369 A AU2003217369 A AU 2003217369A AU 2003217369 A AU2003217369 A AU 2003217369A AU 2003217369 A1 AU2003217369 A1 AU 2003217369A1
Authority
AU
Australia
Prior art keywords
proteins
reactions
nucleic acids
submicroliter
performing submicroliter
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2003217369A
Other versions
AU2003217369A8 (en
Inventor
Stevan Bogdan Jovanovich
Jeng-Thun Li
Oscar Salas-Solano
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Integenx Acquisition Corp
Original Assignee
Amersham Biosciences SV Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US10/262,476 external-priority patent/US6927045B2/en
Application filed by Amersham Biosciences SV Corp filed Critical Amersham Biosciences SV Corp
Publication of AU2003217369A1 publication Critical patent/AU2003217369A1/en
Publication of AU2003217369A8 publication Critical patent/AU2003217369A8/en
Abandoned legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L7/00—Heating or cooling apparatus; Heat insulating devices
    • B01L7/52—Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/02—Burettes; Pipettes
    • B01L3/0241—Drop counters; Drop formers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L9/00—Supporting devices; Holding devices
    • B01L9/06—Test-tube stands; Test-tube holders
    • B01L9/065—Test-tube stands; Test-tube holders specially adapted for capillary tubes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/00279—Features relating to reactor vessels
    • B01J2219/00281—Individual reactor vessels
    • B01J2219/00286—Reactor vessels with top and bottom openings
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/00351—Means for dispensing and evacuation of reagents
    • B01J2219/00364—Pipettes
    • B01J2219/00367—Pipettes capillary
    • B01J2219/00369—Pipettes capillary in multiple or parallel arrangements
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/00497—Features relating to the solid phase supports
    • B01J2219/00511—Walls of reactor vessels
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00585—Parallel processes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/0068—Means for controlling the apparatus of the process
    • B01J2219/00686—Automatic
    • B01J2219/00691—Automatic using robots
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/0068—Means for controlling the apparatus of the process
    • B01J2219/00702—Processes involving means for analysing and characterising the products
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00718—Type of compounds synthesised
    • B01J2219/0072—Organic compounds
    • B01J2219/00722—Nucleotides
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0832—Geometry, shape and general structure cylindrical, tube shaped
    • B01L2300/0838—Capillaries
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/18—Means for temperature control
    • B01L2300/1838—Means for temperature control using fluid heat transfer medium
    • B01L2300/1844—Means for temperature control using fluid heat transfer medium using fans
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0409—Moving fluids with specific forces or mechanical means specific forces centrifugal forces
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5025—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures for parallel transport of multiple samples
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B40/00—Libraries per se, e.g. arrays, mixtures
    • C40B40/04—Libraries containing only organic compounds
    • C40B40/06—Libraries containing nucleotides or polynucleotides, or derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B60/00—Apparatus specially adapted for use in combinatorial chemistry or with libraries
    • C40B60/14—Apparatus specially adapted for use in combinatorial chemistry or with libraries for creating libraries

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
AU2003217369A 2002-02-08 2003-02-07 Method and apparatus for performing submicroliter reactions with nucleic acids or proteins Abandoned AU2003217369A1 (en)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US35566002P 2002-02-08 2002-02-08
US35564802P 2002-02-08 2002-02-08
US60/355,660 2002-02-08
US60/355,648 2002-02-08
US10/262,476 2002-09-30
US10/262,476 US6927045B2 (en) 1999-08-02 2002-09-30 Methods and apparatus for template capture and normalization for submicroliter reaction
PCT/US2003/003986 WO2003066667A2 (en) 2002-02-08 2003-02-07 Method and apparatus for performing submicroliter reactions with nucleic acids or proteins

Publications (2)

Publication Number Publication Date
AU2003217369A1 true AU2003217369A1 (en) 2003-09-02
AU2003217369A8 AU2003217369A8 (en) 2003-09-02

Family

ID=27739086

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2003217369A Abandoned AU2003217369A1 (en) 2002-02-08 2003-02-07 Method and apparatus for performing submicroliter reactions with nucleic acids or proteins

Country Status (5)

Country Link
EP (1) EP1567656A2 (en)
JP (1) JP2005525797A (en)
AU (1) AU2003217369A1 (en)
CA (1) CA2474429A1 (en)
WO (1) WO2003066667A2 (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050282270A1 (en) * 2004-06-21 2005-12-22 Applera Corporation System for thermally cycling biological samples with heated lid and pneumatic actuator
EP1783492A3 (en) * 2005-11-07 2007-05-30 Nisshinbo Industries, Inc. Tip for biomolecular reaction containing an immobilized biomolecule
EP2362907A4 (en) * 2008-11-04 2012-08-08 Blood Cell Storage Inc Nucleic acid extraction on curved glass surfaces
DK2848309T3 (en) * 2013-09-13 2020-09-07 Nanotemper Tech Gmbh CARRIER FOR CAPITAL PIPES
US9993819B2 (en) 2014-12-30 2018-06-12 Stmicroelectronics S.R.L. Apparatus for actuating and reading a centrifugal microfluidic disk for biological and biochemical analyses, and use of the apparatus
GB201501603D0 (en) * 2015-01-30 2015-03-18 Norwegian University Of Life Sciences And Hedmark University College Method and product
CN213301769U (en) * 2019-08-01 2021-05-28 利多(香港)有限公司 Single-person quality control product preservation device
CN114441264B (en) * 2022-01-20 2023-05-30 复旦大学 Skin upgrading volume single-cell sample schizolysis enzymolysis reactor

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5846727A (en) * 1996-06-06 1998-12-08 Board Of Supervisors Of Louisiana State University And Agricultural & Mechanical College Microsystem for rapid DNA sequencing
US6423536B1 (en) * 1999-08-02 2002-07-23 Molecular Dynamics, Inc. Low volume chemical and biochemical reaction system
US6290995B1 (en) * 2000-02-08 2001-09-18 Zhao Xinxian Plant drug for preventing cancer II

Also Published As

Publication number Publication date
JP2005525797A (en) 2005-09-02
CA2474429A1 (en) 2003-08-14
WO2003066667A2 (en) 2003-08-14
EP1567656A2 (en) 2005-08-31
WO2003066667A3 (en) 2005-06-02
AU2003217369A8 (en) 2003-09-02

Similar Documents

Publication Publication Date Title
AU2001283916A1 (en) Method and nucleic acids for the analysis of astrocytomas
AU2002254321A1 (en) Method and apparatus for the automated generation of nucleic acid ligands
AU2003202026A1 (en) Method for isolating nucleic acids and protein from a single sample
AU2003243505A1 (en) Apparatus and method for the purification of nucleic acids
AU2002354006A1 (en) Method and apparatus for dna collection
AU2002329417A1 (en) Method and apparatus for data analysis
AU2001234739A1 (en) Method and apparatus for developing dna microarrays
AU2002337030A1 (en) Method for analyzing nucleic acid sequences and gene expression
AU2003254175A1 (en) Device and method for purification of nucleic acids
AU2003271441A1 (en) Method and apparatus for data analysis
AU2003303361A1 (en) Analysis apparatus and method
AU2003264805A1 (en) Automated kinetci solubility assay apparatus and method
AU2003291471A1 (en) Apparatus and method for confining eluted samples in electrophoresis systems
AU2002365280A1 (en) System and method for simulating laboratory experiment
AU2002363867A1 (en) Method and nucleic acids for the analysis of a lung cell proliferative disorder
AU7111900A (en) Method and apparatus for analyzing nucleic acid sequences
AU2003250989A1 (en) Method and nucleic acids for the analysis of breast cell proliferative disorders
AU2002312070A1 (en) Method and apparatus for facilitating the creation and analysis of microarrays
AU2003256298A1 (en) Method for sequencing nucleic acids
AU2003217369A1 (en) Method and apparatus for performing submicroliter reactions with nucleic acids or proteins
AU2001265394A1 (en) Method and apparatus for purifying nucleic acids
AU2003303588A1 (en) Methods and compositions for sequencing nucleic acid molecules
AU2002352143A1 (en) Method and nucleic acids for the analysis of a lymphoid cell proliferative disorder
AU2003288124A1 (en) Method for purifying nucleic acids
AU2002367604A1 (en) Apparatus and method for designing proteins and protein libraries

Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase