AU2002365664A1 - Quinoline derivatives as antitumour agents - Google Patents

Quinoline derivatives as antitumour agents

Info

Publication number
AU2002365664A1
AU2002365664A1 AU2002365664A AU2002365664A AU2002365664A1 AU 2002365664 A1 AU2002365664 A1 AU 2002365664A1 AU 2002365664 A AU2002365664 A AU 2002365664A AU 2002365664 A AU2002365664 A AU 2002365664A AU 2002365664 A1 AU2002365664 A1 AU 2002365664A1
Authority
AU
Australia
Prior art keywords
quinoline derivatives
antitumour agents
antitumour
agents
quinoline
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2002365664A
Inventor
Kevin Michael Foote
Keith Hopkinson Gibson
Laurent Francois Andre Hennequin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AstraZeneca AB
Original Assignee
AstraZeneca AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by AstraZeneca AB filed Critical AstraZeneca AB
Publication of AU2002365664A1 publication Critical patent/AU2002365664A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
AU2002365664A 2001-12-05 2002-12-05 Quinoline derivatives as antitumour agents Abandoned AU2002365664A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP01403128 2001-12-05
EP01403128.0 2001-12-05
PCT/GB2002/005496 WO2003047582A1 (en) 2001-12-05 2002-12-05 Quinoline derivatives as antitumour agents

Publications (1)

Publication Number Publication Date
AU2002365664A1 true AU2002365664A1 (en) 2003-06-17

Family

ID=8183003

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2002365664A Abandoned AU2002365664A1 (en) 2001-12-05 2002-12-05 Quinoline derivatives as antitumour agents

Country Status (2)

Country Link
AU (1) AU2002365664A1 (en)
WO (1) WO2003047582A1 (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2003281193A1 (en) 2002-07-09 2004-01-23 Astrazeneca Ab Quinazoline derivatives for use in the treatment of cancer
GB0215823D0 (en) 2002-07-09 2002-08-14 Astrazeneca Ab Quinazoline derivatives
GB0225579D0 (en) 2002-11-02 2002-12-11 Astrazeneca Ab Chemical compounds
RU2350618C2 (en) 2002-11-04 2009-03-27 Астразенека Аб QUINAZOLINE DERIVATIVES AS Src TYROSINE KINASE INHIBITORS
WO2005046665A1 (en) * 2003-11-13 2005-05-26 Warner-Lambert Company Llc Combination chemotherapy comprising a mek inhibitor and a erbb1/2 receptor inhibitor
US20110281909A1 (en) 2007-08-15 2011-11-17 Glaxo Group Limited Substituted quinoline derivatives as h1 receptor antagonists
CN103539702B (en) * 2012-07-12 2016-03-30 陕西师范大学 The novel preparation method of N '-aryl-N, N-dimethyl carbonamidine
BR112018006873A2 (en) 2015-10-05 2018-11-06 The Trustees Of Columbia University In The City Of New York autophageal flow activators and phospholipase d and clearance of protein aggregates including tau and treatment of proteinopathies

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5721237A (en) * 1991-05-10 1998-02-24 Rhone-Poulenc Rorer Pharmaceuticals Inc. Protein tyrosine kinase aryl and heteroaryl quinazoline compounds having selective inhibition of HER-2 autophosphorylation properties
UA73073C2 (en) * 1997-04-03 2005-06-15 Уайт Холдінгз Корпорейшн Substituted 3-cyan chinolines
DK1117659T3 (en) * 1998-09-29 2004-03-22 Wyeth Corp Substituted 3-cyanoquinolines as inhibitors of protein tyrosine kinases
US6288082B1 (en) * 1998-09-29 2001-09-11 American Cyanamid Company Substituted 3-cyanoquinolines
GB9910577D0 (en) * 1999-05-08 1999-07-07 Zeneca Ltd Chemical compounds
US6521618B2 (en) * 2000-03-28 2003-02-18 Wyeth 3-cyanoquinolines, 3-cyano-1,6-naphthyridines, and 3-cyano-1,7-naphthyridines as protein kinase inhibitors
UA73993C2 (en) * 2000-06-06 2005-10-17 Астразенека Аб Quinazoline derivatives for the treatment of tumours and a pharmaceutical composition
NZ523702A (en) * 2000-08-21 2004-08-27 Astrazeneca Ab Quinazoline derivatives

Also Published As

Publication number Publication date
WO2003047582A1 (en) 2003-06-12

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase