AU2002362806A1 - Pyrimidine derivatives - Google Patents

Pyrimidine derivatives

Info

Publication number
AU2002362806A1
AU2002362806A1 AU2002362806A AU2002362806A AU2002362806A1 AU 2002362806 A1 AU2002362806 A1 AU 2002362806A1 AU 2002362806 A AU2002362806 A AU 2002362806A AU 2002362806 A AU2002362806 A AU 2002362806A AU 2002362806 A1 AU2002362806 A1 AU 2002362806A1
Authority
AU
Australia
Prior art keywords
pyrimidine derivatives
pyrimidine
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
AU2002362806A
Other versions
AU2002362806B2 (en
Inventor
Manfred Baumgarth
Norbert Beier
Maria Christadler
Hans-Michael Eggenweiler
Pierre Schelling
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Patent GmbH
Original Assignee
Merck Patent GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE10148883A external-priority patent/DE10148883A1/en
Application filed by Merck Patent GmbH filed Critical Merck Patent GmbH
Publication of AU2002362806A1 publication Critical patent/AU2002362806A1/en
Application granted granted Critical
Publication of AU2002362806B2 publication Critical patent/AU2002362806B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

AU2002362806A 2001-10-04 2002-09-05 Pyrimidine derivatives Ceased AU2002362806B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE10148883A DE10148883A1 (en) 2001-10-04 2001-10-04 New fused bi- or tricyclic pyrimidine derivatives, are phosphodiesterase V inhibitors useful e.g. for treating impotence, cardiovascular disorders, inflammation or tumors
DE10148883.1 2001-10-04
PCT/EP2002/009935 WO2003031447A2 (en) 2001-10-04 2002-09-05 Pyrimidine derivatives

Publications (2)

Publication Number Publication Date
AU2002362806A1 true AU2002362806A1 (en) 2003-07-03
AU2002362806B2 AU2002362806B2 (en) 2008-09-18

Family

ID=7701322

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2002362806A Ceased AU2002362806B2 (en) 2001-10-04 2002-09-05 Pyrimidine derivatives

Country Status (16)

Country Link
US (1) US7312224B2 (en)
EP (1) EP1432715B1 (en)
JP (1) JP4782376B2 (en)
KR (1) KR20040041166A (en)
CN (1) CN1863803A (en)
AT (1) ATE389655T1 (en)
AU (1) AU2002362806B2 (en)
BR (1) BR0213037A (en)
CA (1) CA2462799C (en)
DE (2) DE10148883A1 (en)
ES (1) ES2303564T3 (en)
HU (1) HUP0401654A3 (en)
PL (1) PL369819A1 (en)
RU (1) RU2004114239A (en)
WO (1) WO2003031447A2 (en)
ZA (1) ZA200403334B (en)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102005061171A1 (en) * 2005-12-21 2007-07-05 Bayer Healthcare Ag New furopyrimidine derivatives useful for treating cardiovascular diseases
DE102005061170A1 (en) * 2005-12-21 2007-07-05 Bayer Healthcare Ag New furo-pyrimidine derivatives, useful for treating cardiovascular disease, e. g. angina or hypertension, are activators of prostacyclin receptors
AR062501A1 (en) * 2006-08-29 2008-11-12 Actelion Pharmaceuticals Ltd THERAPEUTIC COMPOSITIONS
CA2671782C (en) * 2006-12-07 2017-01-10 F. Hoffmann-La Roche Ag Phosphoinositide 3-kinase inhibitor compounds and methods of use
DE102007027799A1 (en) * 2007-06-16 2008-12-18 Bayer Healthcare Ag Substituted furopyrimidines and their use
DE102007027800A1 (en) * 2007-06-16 2008-12-18 Bayer Healthcare Ag Substituted bicyclic heteroaryl compounds and their use
DE102007051762A1 (en) * 2007-10-30 2009-05-07 Bayer Healthcare Ag Substituted pyrrolotriazines and their use
DE102007054786A1 (en) * 2007-11-16 2009-05-20 Bayer Healthcare Ag Trisubstituted Furopyrimidines and their Use
WO2011143607A1 (en) * 2010-05-14 2011-11-17 The Regents Of The University Of California Modulation of bioactive epoxy-fatty acid levels by phosphodiesterase inhibitors
JP6042331B2 (en) 2010-07-23 2016-12-14 プレジデント アンド フェローズ オブ ハーバード カレッジ Tricyclic compounds that improve proteasome activity
EP2806875B1 (en) * 2012-01-25 2017-07-19 Proteostasis Therapeutics, Inc. Proteasome activity modulating compounds
WO2016042349A1 (en) 2014-09-17 2016-03-24 Pécsi Tudományegyetem New agents for treating neurogenic inflammation and neuropathic hyperalgesia related disorders
US10813894B2 (en) 2015-02-20 2020-10-27 The Regents Of The University Of California Methods of inhibiting pain
CN108137614B (en) * 2015-12-02 2021-01-05 深圳市塔吉瑞生物医药有限公司 Fused pyrimidine compound, composition containing compound and application of compound
CN105461728A (en) * 2015-12-29 2016-04-06 中山大学 4-substituted amino-6-methoxycarbonyl group benzofuran and [2,3-d] pyrimidine compound and preparing method
RU2625316C1 (en) * 2016-04-13 2017-07-13 Федеральное государственное бюджетное учреждение науки Институт элементоорганических соединений им. А.Н. Несмеянова Российской академии наук (ИНЭОС РАН) 2-amino-substituted 6-methoxy-4-trifluoromethyl-9h-pyrimido[4,5b]indoles, method for their production, application and prediminaries

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3037980A (en) * 1955-08-18 1962-06-05 Burroughs Wellcome Co Pyrrolopyrimidine vasodilators and method of making them
GB915304A (en) * 1958-03-13 1963-01-09 Wellcome Found Pyrrolo[2,3-d]pyrimidine derivatives
JPS5542999B2 (en) * 1972-02-14 1980-11-04
CH592668A5 (en) * 1973-10-02 1977-10-31 Delalande Sa
ZA815765B (en) * 1980-08-22 1983-04-27 Du Pont Herbicidal sulfonamides
US4487626A (en) 1980-08-22 1984-12-11 E. I. Du Pont De Nemours And Company Herbicidal sulfonamides
DE69027862T2 (en) 1989-09-19 1997-03-06 Teijin Ltd PYRROLO [2,3-D] PYRIMIDINE DERIVATIVES, METHOD FOR THE PRODUCTION AND MEDICINAL COMPOSITIONS CONTAINING THEM
JP2562520B2 (en) * 1989-09-19 1996-12-11 帝人株式会社 Pyrrolo [2,3-d] pyrimidine derivative, method for producing the same and pharmaceutical preparation containing the same as an active ingredient
US5869486A (en) 1995-02-24 1999-02-09 Ono Pharmaceutical Co., Ltd. Fused pyrimidines and pyriazines as pharmaceutical compounds
DE19644228A1 (en) 1996-10-24 1998-04-30 Merck Patent Gmbh Thienopyrimidines
DE19752952A1 (en) 1997-11-28 1999-06-02 Merck Patent Gmbh Thienopyrimidines
DE19819023A1 (en) 1998-04-29 1999-11-04 Merck Patent Gmbh Thienopyrimidines
AU763658B2 (en) 1998-06-02 2003-07-31 Osi Pharmaceuticals, Inc. Pyrrolo(2,3d)pyrimidine compositions and their use
DE19942474A1 (en) 1999-09-06 2001-03-15 Merck Patent Gmbh Pyrazolo [4,3-d] pyrimidines
DE19944604A1 (en) 1999-09-17 2001-03-22 Merck Patent Gmbh Amine derivatives
ATE335489T1 (en) 1999-12-02 2006-09-15 Osi Pharm Inc ADENOSINE A3, A2A AND A3 RECEPTORS SPECIFIC COMPOUNDS AND THEIR USES
MEP35308A (en) 2000-12-01 2011-02-10 Osi Pharm Inc COMPOUNDS SPECIFIC TO ADENOSINE A1, A2a, AND A3 RECEPTOR AND USES THEREOF

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