AU2002214626A1 - Quaternary amines and related inhibitors of factor xa - Google Patents
Quaternary amines and related inhibitors of factor xaInfo
- Publication number
- AU2002214626A1 AU2002214626A1 AU2002214626A AU1462602A AU2002214626A1 AU 2002214626 A1 AU2002214626 A1 AU 2002214626A1 AU 2002214626 A AU2002214626 A AU 2002214626A AU 1462602 A AU1462602 A AU 1462602A AU 2002214626 A1 AU2002214626 A1 AU 2002214626A1
- Authority
- AU
- Australia
- Prior art keywords
- factor
- quaternary amines
- related inhibitors
- inhibitors
- quaternary
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/81—Amides; Imides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US23633000P | 2000-09-29 | 2000-09-29 | |
| US60/236,330 | 2000-09-29 | ||
| PCT/US2001/042352 WO2002026712A2 (en) | 2000-09-29 | 2001-10-01 | Quaternary amines and related inhibitors of factor xa |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AU2002214626A1 true AU2002214626A1 (en) | 2002-04-08 |
Family
ID=22889060
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2002214626A Abandoned AU2002214626A1 (en) | 2000-09-29 | 2001-10-01 | Quaternary amines and related inhibitors of factor xa |
Country Status (3)
| Country | Link |
|---|---|
| US (1) | US20040067938A1 (en) |
| AU (1) | AU2002214626A1 (en) |
| WO (1) | WO2002026712A2 (en) |
Families Citing this family (37)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI288745B (en) | 2000-04-05 | 2007-10-21 | Daiichi Seiyaku Co | Ethylenediamine derivatives |
| US7365205B2 (en) | 2001-06-20 | 2008-04-29 | Daiichi Sankyo Company, Limited | Diamine derivatives |
| EP1542692B1 (en) | 2002-05-22 | 2011-01-05 | Amgen Inc. | Aminopyrimidine derivatives for use as vanilloid receptor ligands for the treatment of pain |
| PL376372A1 (en) | 2002-08-08 | 2005-12-27 | Amgen Inc. | Vanilloid receptor ligands and their use in treatments |
| CA2541809A1 (en) * | 2003-10-09 | 2005-04-21 | Millennium Pharmaceuticals, Inc. | Thioether-substituted benzamides as inhibitors of factor xa |
| WO2005077938A1 (en) | 2004-02-11 | 2005-08-25 | Amgen Inc. | Vanilloid receptor ligands and their use in treatments |
| MY139645A (en) | 2004-02-11 | 2009-10-30 | Amgen Inc | Vanilloid receptor ligands and their use in treatments |
| US7301022B2 (en) | 2005-02-15 | 2007-11-27 | Amgen Inc. | Vanilloid receptor ligands and their use in treatments |
| UA103319C2 (en) | 2008-05-06 | 2013-10-10 | Глаксосмитклайн Ллк | Thiazole- and oxazole-benzene sulfonamide compounds |
| US8124764B2 (en) | 2008-07-14 | 2012-02-28 | Gilead Sciences, Inc. | Fused heterocyclyc inhibitor compounds |
| JP5640005B2 (en) | 2008-07-14 | 2014-12-10 | ギリアード サイエンシーズ， インコーポレイテッド | Imidazosylpyridine compounds as HDAC and / or CDK inhibitors |
| US8344018B2 (en) | 2008-07-14 | 2013-01-01 | Gilead Sciences, Inc. | Oxindolyl inhibitor compounds |
| MX2011001090A (en) | 2008-07-28 | 2011-03-15 | Gilead Sciences Inc | Cycloalkylidene and heterocycloalkylidene histone deacetylase inhibitor compounds. |
| FR2942456B1 (en) | 2009-02-25 | 2012-12-07 | Sicma Aero Seat | MODULE FOR AIRCRAFT CABIN AND ASSOCIATED AIRCRAFT CABIN. |
| CA2763786C (en) | 2009-06-08 | 2014-09-30 | Gilead Sciences, Inc. | Alkanoylamino benzamide aniline hdac inihibitor compounds |
| KR20120024722A (en) | 2009-06-08 | 2012-03-14 | 길리애드 사이언시즈, 인코포레이티드 | Cycloalkylcarbamate benzamide aniline hdac inhibitor compounds |
| AR081626A1 (en) | 2010-04-23 | 2012-10-10 | Cytokinetics Inc | AMINO-PYRIDAZINIC COMPOUNDS, PHARMACEUTICAL COMPOSITIONS THAT CONTAIN THEM AND USE OF THE SAME TO TREAT CARDIAC AND SKELETIC MUSCULAR DISORDERS |
| AR081331A1 (en) | 2010-04-23 | 2012-08-08 | Cytokinetics Inc | AMINO- PYRIMIDINES COMPOSITIONS OF THE SAME AND METHODS FOR THE USE OF THE SAME |
| US9133123B2 (en) | 2010-04-23 | 2015-09-15 | Cytokinetics, Inc. | Certain amino-pyridines and amino-triazines, compositions thereof, and methods for their use |
| GB201007203D0 (en) | 2010-04-29 | 2010-06-16 | Glaxo Group Ltd | Novel compounds |
| US8440662B2 (en) | 2010-10-31 | 2013-05-14 | Endo Pharmaceuticals, Inc. | Substituted quinazoline and pyrido-pyrimidine derivatives |
| EP2683710B1 (en) | 2011-03-10 | 2017-07-19 | Boehringer Ingelheim International GmbH | Soluble guanylate cyclase activators |
| EP2766360B1 (en) | 2011-08-12 | 2017-07-12 | Boehringer Ingelheim International GmbH | Soluble guanylate cyclase activators |
| AP2015008231A0 (en) | 2012-09-07 | 2015-01-31 | Boehringer Ingelheim Int | Alkoxy pyrazoles as soluble guanylate cyclase activators |
| HUE049231T2 (en) | 2014-07-22 | 2020-09-28 | Boehringer Ingelheim Int | Heterocyclic carboxylic acids as activators of soluble guanylate cyclase |
| CA3129131A1 (en) | 2019-03-11 | 2020-09-17 | Bridget Mccarthy Cole | Charged ion channel blockers and methods for use |
| AU2020234961A1 (en) | 2019-03-11 | 2021-09-30 | Nocion Therapeutics, Inc. | Charged ion channel blockers and methods for use |
| US10786485B1 (en) | 2019-03-11 | 2020-09-29 | Nocion Therapeutics, Inc. | Charged ion channel blockers and methods for use |
| KR20210145164A (en) * | 2019-03-11 | 2021-12-01 | 녹시온 테라퓨틱스 인코포레이티드 | Ester Substituted Ion Channel Blockers and Methods of Use |
| WO2021030405A1 (en) | 2019-08-12 | 2021-02-18 | Deciphera Pharmaceuticals, Llc | Ripretinib for treating gastrointestinal stromal tumors |
| MX2022001863A (en) | 2019-08-12 | 2022-05-30 | Deciphera Pharmaceuticals Llc | Ripretinib for treating gastrointestinal stromal tumors. |
| US10842798B1 (en) | 2019-11-06 | 2020-11-24 | Nocion Therapeutics, Inc. | Charged ion channel blockers and methods for use |
| EP4054586A4 (en) | 2019-11-06 | 2023-11-22 | Nocion Therapeutics, Inc. | Charged ion channel blockers and methods for use |
| KR20220123058A (en) | 2019-12-30 | 2022-09-05 | 데시페라 파마슈티칼스, 엘엘씨. | 1-(4-Bromo-5-(1-ethyl-7-(methylamino)-2-oxo-1,2-dihydro-1,6-naphthyridin-3-yl)-2-fluorophenyl ) -3-Phenylurea composition |
| MX2022008103A (en) | 2019-12-30 | 2022-09-19 | Deciphera Pharmaceuticals Llc | Amorphous kinase inhibitor formulations and methods of use thereof. |
| KR20230022830A (en) | 2020-03-11 | 2023-02-16 | 녹시온 테라퓨틱스 인코포레이티드 | Charged ion channel blockers and methods of use |
| US11779572B1 (en) | 2022-09-02 | 2023-10-10 | Deciphera Pharmaceuticals, Llc | Methods of treating gastrointestinal stromal tumors |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3811006B2 (en) * | 1997-12-19 | 2006-08-16 | シエーリング アクチエンゲゼルシャフト | Ortho-anthranilamide derivatives as anticoagulants |
| DE69829879T2 (en) * | 1997-12-24 | 2006-03-02 | Sanofi-Aventis Deutschland Gmbh | INDOLE DERIVATIVES AS FACTOR XA INHIBITORS |
-
2001
- 2001-10-01 WO PCT/US2001/042352 patent/WO2002026712A2/en active Application Filing
- 2001-10-01 AU AU2002214626A patent/AU2002214626A1/en not_active Abandoned
- 2001-10-01 US US10/381,925 patent/US20040067938A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| WO2002026712A3 (en) | 2002-10-17 |
| WO2002026712A2 (en) | 2002-04-04 |
| US20040067938A1 (en) | 2004-04-08 |
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