AU2002212690A1 - Process for producing d-serine - Google Patents

Process for producing d-serine

Info

Publication number
AU2002212690A1
AU2002212690A1 AU2002212690A AU1269002A AU2002212690A1 AU 2002212690 A1 AU2002212690 A1 AU 2002212690A1 AU 2002212690 A AU2002212690 A AU 2002212690A AU 1269002 A AU1269002 A AU 1269002A AU 2002212690 A1 AU2002212690 A1 AU 2002212690A1
Authority
AU
Australia
Prior art keywords
serine
producing
cell
medium
useful
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2002212690A
Inventor
Shinichi Hashimoto
Hajime Ikeda
Yoshiyuki Yonetani
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
KH Neochem Co Ltd
Original Assignee
Kyowa Hakko Kogyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kyowa Hakko Kogyo Co Ltd filed Critical Kyowa Hakko Kogyo Co Ltd
Publication of AU2002212690A1 publication Critical patent/AU2002212690A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/06—Alanine; Leucine; Isoleucine; Serine; Homoserine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
    • C12P41/001—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by metabolizing one of the enantiomers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/185—Escherichia
    • C12R2001/19—Escherichia coli

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Analytical Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

The present invention relates to: a process for producing D-serine wherein a microbial cell which is modified to have a higher L-serine deaminase activity than Escherichia coli DH5 alpha strain, a culture of said cell, or a processed product thereof is brought into contact with DL-serine in a DL-serine-containing medium to decompose L-serine, and the remaining D-serine is recovered from the medium; and a microorganism used for this production process. D-serine is a useful compound as a synthetic intermediate for useful medicaments such as D-cycloserine.
AU2002212690A 2000-11-01 2001-10-29 Process for producing d-serine Abandoned AU2002212690A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2000334751 2000-11-01
JP2000-334751 2000-11-01
PCT/JP2001/009482 WO2002036803A1 (en) 2000-11-01 2001-10-29 Process for producing d-serine

Publications (1)

Publication Number Publication Date
AU2002212690A1 true AU2002212690A1 (en) 2002-05-15

Family

ID=18810608

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2002212690A Abandoned AU2002212690A1 (en) 2000-11-01 2001-10-29 Process for producing d-serine

Country Status (8)

Country Link
US (1) US7186532B2 (en)
EP (1) EP1331274B1 (en)
JP (1) JP4308521B2 (en)
KR (1) KR100815085B1 (en)
CN (1) CN1280424C (en)
AT (1) ATE518962T1 (en)
AU (1) AU2002212690A1 (en)
WO (1) WO2002036803A1 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7919285B2 (en) * 2004-10-13 2011-04-05 Mitsui Chemicals, Inc. DNA encoding novel enzyme having D-serine synthase activity, method of producing the enzyme and method of producing D-serine by using the same
EP1956090A4 (en) 2005-11-29 2009-04-08 Kyowa Hakko Kogyo Kk Novel protein and dna encoding the protein
CN101168513B (en) * 2007-11-28 2012-06-27 上海化学试剂研究所 Method for preparing DL-serine
DE102010025124A1 (en) 2010-06-25 2011-12-29 Forschungszentrum Jülich GmbH Process for the preparation of D-amino acids, microorganism, and vector
CN117736959B (en) * 2024-01-26 2024-05-14 湖北大学 Engineering strain of zymomonas mobilis, preparation method and application

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0591895A (en) 1991-08-12 1993-04-16 Mitsubishi Petrochem Co Ltd Production of d-serine
US5728555A (en) 1996-09-30 1998-03-17 Monsanto Company Preparation of d-amino acids by direct fermentative means

Also Published As

Publication number Publication date
US20040072308A1 (en) 2004-04-15
ATE518962T1 (en) 2011-08-15
KR20030066648A (en) 2003-08-09
WO2002036803A1 (en) 2002-05-10
EP1331274B1 (en) 2011-08-03
EP1331274A4 (en) 2005-08-10
CN1531599A (en) 2004-09-22
EP1331274A1 (en) 2003-07-30
US7186532B2 (en) 2007-03-06
JP4308521B2 (en) 2009-08-05
JPWO2002036803A1 (en) 2004-03-11
KR100815085B1 (en) 2008-03-20
CN1280424C (en) 2006-10-18

Similar Documents

Publication Publication Date Title
FI87579B (en) FRAMEWORK FOR MICRO-ORGANISMS
CN105378059B (en) Produce l-Isoleucine microorganism and the method using the micro-organisms l-Isoleucine
RU2003122076A (en) METHOD FOR ENZYMATIC PRODUCTION OF AMINO ACIDS AND DERIVATED AMINO ACIDS FROM THE PHOSPHOGLYCERATE FAMILY
HUP0204295A2 (en) Process for producing l-lysine
Desai et al. Production, purification and characterization of L-Glutaminase from Streptomyces sp. isolated from soil
CA1217158A (en) Enzymatic synthesis of l-serine
AU2002212690A1 (en) Process for producing d-serine
CA2177785A1 (en) A method for producing l-isoleucine with a fermentation process
FR2511035A1 (en) PROCESS FOR THE PRODUCTION OF L-LYSINE BY FERMENTATION
KR100902396B1 (en) Product
JP3154646B2 (en) Microbial production of glycolic acid
DE10251184A1 (en) Recombinant microorganism for D-amino acid production, useful as intermediates for pharmaceuticals, has genes involved in D-amino acid degradation inactivated, for improved yield
WO2003000910A3 (en) Metabolic controlled fermentation process for pseudomonic acid production
AU2321900A (en) Process for the preparation of alpha-aminoketones
AU2003206934A1 (en) Fermentation process
US4906572A (en) Method of culturing amino acid racemase-producing microorganism of genus pseudomonas
JP4198147B2 (en) Method for producing organic acid
Dhillon et al. Microbial process for L-cysteine production
JP2008306928A (en) Method for culturing microorganism capable of producing cobalt-containing nitrile hydratase
MY130276A (en) Methods to produce theanine
JPS6143997B2 (en)
EP2130925A1 (en) Method for production of optically active amino acid
JP2008067626A (en) Method for producing 4-halo-3-hydroxybutyramide
JP2008148637A (en) Method for producing 4-halo-3-hydroxybutyramide
RU2337954C1 (en) Strain of bacteria alcaligenes denitrificans -nitrilase producent