AU2001281782A1 - Integrated optical waveguides for microfluidic analysis systems - Google Patents

Integrated optical waveguides for microfluidic analysis systems

Info

Publication number
AU2001281782A1
AU2001281782A1 AU2001281782A AU8178201A AU2001281782A1 AU 2001281782 A1 AU2001281782 A1 AU 2001281782A1 AU 2001281782 A AU2001281782 A AU 2001281782A AU 8178201 A AU8178201 A AU 8178201A AU 2001281782 A1 AU2001281782 A1 AU 2001281782A1
Authority
AU
Australia
Prior art keywords
optical waveguides
integrated optical
analysis systems
microfluidic analysis
microfluidic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001281782A
Inventor
Thomas Greve
Gunter Hauke
Matthias Johnck
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Patent GmbH
Original Assignee
Merck Patent GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent GmbH filed Critical Merck Patent GmbH
Publication of AU2001281782A1 publication Critical patent/AU2001281782A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502715Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by interfacing components, e.g. fluidic, electrical, optical or mechanical interfaces
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502707Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the manufacture of the container or its components
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/416Systems
    • G01N27/447Systems using electrophoresis
    • G01N27/44704Details; Accessories
    • G01N27/44717Arrangements for investigating the separated zones, e.g. localising zones
    • G01N27/44721Arrangements for investigating the separated zones, e.g. localising zones by optical means
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/416Systems
    • G01N27/447Systems using electrophoresis
    • G01N27/44756Apparatus specially adapted therefor
    • G01N27/44791Microapparatus
    • GPHYSICS
    • G02OPTICS
    • G02BOPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B6/00Light guides; Structural details of arrangements comprising light guides and other optical elements, e.g. couplings
    • G02B6/10Light guides; Structural details of arrangements comprising light guides and other optical elements, e.g. couplings of the optical waveguide type
    • G02B6/12Light guides; Structural details of arrangements comprising light guides and other optical elements, e.g. couplings of the optical waveguide type of the integrated circuit kind
    • G02B6/13Integrated optical circuits characterised by the manufacturing method
    • G02B6/138Integrated optical circuits characterised by the manufacturing method by using polymerisation
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/06Auxiliary integrated devices, integrated components
    • B01L2300/0627Sensor or part of a sensor is integrated
    • B01L2300/0645Electrodes
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/06Auxiliary integrated devices, integrated components
    • B01L2300/0627Sensor or part of a sensor is integrated
    • B01L2300/0654Lenses; Optical fibres
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/08Geometry, shape and general structure
    • B01L2300/0809Geometry, shape and general structure rectangular shaped
    • B01L2300/0825Test strips
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/08Geometry, shape and general structure
    • B01L2300/0887Laminated structure
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00Moving or stopping fluids
    • B01L2400/04Moving fluids with specific forces or mechanical means
    • B01L2400/0403Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0415Moving fluids with specific forces or mechanical means specific forces electrical forces, e.g. electrokinetic
    • GPHYSICS
    • G02OPTICS
    • G02BOPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B6/00Light guides; Structural details of arrangements comprising light guides and other optical elements, e.g. couplings
    • G02B6/10Light guides; Structural details of arrangements comprising light guides and other optical elements, e.g. couplings of the optical waveguide type
    • G02B6/12Light guides; Structural details of arrangements comprising light guides and other optical elements, e.g. couplings of the optical waveguide type of the integrated circuit kind
    • G02B2006/12035Materials
    • G02B2006/12069Organic material
    • GPHYSICS
    • G02OPTICS
    • G02BOPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B6/00Light guides; Structural details of arrangements comprising light guides and other optical elements, e.g. couplings
    • G02B6/10Light guides; Structural details of arrangements comprising light guides and other optical elements, e.g. couplings of the optical waveguide type
    • G02B6/12Light guides; Structural details of arrangements comprising light guides and other optical elements, e.g. couplings of the optical waveguide type of the integrated circuit kind
    • G02B2006/12035Materials
    • G02B2006/12069Organic material
    • G02B2006/12071PMMA
    • GPHYSICS
    • G02OPTICS
    • G02BOPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B6/00Light guides; Structural details of arrangements comprising light guides and other optical elements, e.g. couplings
    • G02B6/10Light guides; Structural details of arrangements comprising light guides and other optical elements, e.g. couplings of the optical waveguide type
    • G02B6/12Light guides; Structural details of arrangements comprising light guides and other optical elements, e.g. couplings of the optical waveguide type of the integrated circuit kind
    • G02B2006/12083Constructional arrangements
    • G02B2006/12121Laser
    • GPHYSICS
    • G02OPTICS
    • G02BOPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B6/00Light guides; Structural details of arrangements comprising light guides and other optical elements, e.g. couplings
    • G02B6/10Light guides; Structural details of arrangements comprising light guides and other optical elements, e.g. couplings of the optical waveguide type
    • G02B6/12Light guides; Structural details of arrangements comprising light guides and other optical elements, e.g. couplings of the optical waveguide type of the integrated circuit kind
    • G02B2006/12083Constructional arrangements
    • G02B2006/12123Diode
    • GPHYSICS
    • G02OPTICS
    • G02BOPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B6/00Light guides; Structural details of arrangements comprising light guides and other optical elements, e.g. couplings
    • G02B6/10Light guides; Structural details of arrangements comprising light guides and other optical elements, e.g. couplings of the optical waveguide type
    • G02B6/12Light guides; Structural details of arrangements comprising light guides and other optical elements, e.g. couplings of the optical waveguide type of the integrated circuit kind
    • G02B2006/12133Functions
    • G02B2006/12138Sensor

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Electrochemistry (AREA)
  • Pathology (AREA)
  • Hematology (AREA)
  • Clinical Laboratory Science (AREA)
  • Engineering & Computer Science (AREA)
  • Microelectronics & Electronic Packaging (AREA)
  • Optics & Photonics (AREA)
  • Optical Integrated Circuits (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Optical Measuring Cells (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
AU2001281782A 2000-06-17 2001-05-22 Integrated optical waveguides for microfluidic analysis systems Abandoned AU2001281782A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE10029946A DE10029946A1 (en) 2000-06-17 2000-06-17 Micro-structured, miniaturized planar analytical unit made from polymer, contains integral polymer optical waveguide
DE10029946 2000-06-17
PCT/EP2001/005843 WO2001098759A1 (en) 2000-06-17 2001-05-22 Integrated optical waveguides for microfluidic analysis systems

Publications (1)

Publication Number Publication Date
AU2001281782A1 true AU2001281782A1 (en) 2002-01-02

Family

ID=7646134

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001281782A Abandoned AU2001281782A1 (en) 2000-06-17 2001-05-22 Integrated optical waveguides for microfluidic analysis systems

Country Status (6)

Country Link
US (1) US20030161572A1 (en)
EP (1) EP1292822A1 (en)
JP (1) JP2004501372A (en)
AU (1) AU2001281782A1 (en)
DE (1) DE10029946A1 (en)
WO (1) WO2001098759A1 (en)

Families Citing this family (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7016560B2 (en) 2001-02-28 2006-03-21 Lightwave Microsystems Corporation Microfluidic control for waveguide optical switches, variable attenuators, and other optical devices
US6949176B2 (en) 2001-02-28 2005-09-27 Lightwave Microsystems Corporation Microfluidic control using dielectric pumping
GB2383127B (en) 2001-12-12 2004-10-20 Proimmune Ltd Device and method for investigating analytes in liquid suspension or solution
JP2003227950A (en) * 2002-02-01 2003-08-15 Omron Corp Optical element and method of manufacturing the same
US7226564B2 (en) * 2002-07-26 2007-06-05 Enplas Corporation Plate assembly
JP3880931B2 (en) * 2002-08-23 2007-02-14 株式会社エンプラス Plate assembly structure
JP3880930B2 (en) * 2002-07-26 2007-02-14 株式会社エンプラス Plate adhesive structure
JP4014500B2 (en) * 2002-12-20 2007-11-28 住友ベークライト株式会社 Microchip substrate bonding method and microchip
US20060246573A1 (en) * 2003-07-04 2006-11-02 Kubota Corporation Bio-chip
WO2005053775A1 (en) * 2003-11-27 2005-06-16 Commissariat A L'energie Atomique In vivo diagnostic and therapy micro-device
DE102004015906B4 (en) * 2004-03-31 2006-02-16 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Microfluidic apparatus for use in optical analysis comprises substrate containing fluid channels or reservoirs and optical components, e.g. transmission gratings, for dividing or filtering light which has been refracted by substrate
US7155082B2 (en) * 2004-04-12 2006-12-26 Colorado School Of Mines Switchable microfluidic optical waveguides
DE102004033440A1 (en) * 2004-07-08 2006-02-02 NMI Naturwissenschaftliches und Medizinisches Institut an der Universität Tübingen Microstructured device and method for its production
WO2006015360A1 (en) * 2004-07-30 2006-02-09 President And Fellows Of Harvard College Fluid waveguides and uses thereof
US20100303119A1 (en) * 2005-02-08 2010-12-02 President And Fellows Of Harvard College Microfluidic Lasers
DE112006000642B4 (en) * 2005-03-18 2014-03-13 Nanyang Technological University Microfluidic interfacial tension sensor and method of measuring interfacial tension
US8351741B2 (en) 2005-10-03 2013-01-08 Creatv Microtech, Inc. Sensitive emission light gathering and flow through detection system
US9528939B2 (en) 2006-03-10 2016-12-27 Indx Lifecare, Inc. Waveguide-based optical scanning systems
US9976192B2 (en) 2006-03-10 2018-05-22 Ldip, Llc Waveguide-based detection system with scanning light source
US8399101B2 (en) * 2006-09-19 2013-03-19 E I Du Pont De Nemours And Company Toughened poly(hydroxyalkanoic acid) compositions
KR100799267B1 (en) * 2006-10-13 2008-01-29 이화여자대학교 산학협력단 Micro or nanofluidic chip fabricated by using the norland optical adhesive and bioanalysis platform prepared by using the same
JP2010513910A (en) * 2006-12-21 2010-04-30 コーニンクレッカ フィリップス エレクトロニクス エヌ ヴィ Wire grid waveguide and method
DE102007021544A1 (en) * 2007-05-08 2008-11-13 Siemens Ag Measuring unit and method for optically examining a liquid for an analyte concentration
US20100032582A1 (en) * 2008-08-07 2010-02-11 General Electric Company Fluorescence detection system and method
DE102008038993B4 (en) * 2008-08-13 2011-06-22 Karlsruher Institut für Technologie, 76131 Optical element and method for its production
DE102009025072A1 (en) 2009-06-16 2010-12-30 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. A method of producing a region of increased refractive index and a substrate of locally variable refractive index
DE102009025073A1 (en) * 2009-06-16 2010-12-30 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Optical sensor has channel with opposite side panels which are connected by base, where optical fiber is formed along opposite side panels and along base, so that field generates light in channel by passing to optical fiber
DE102012103628B4 (en) 2012-04-25 2020-12-31 Avl Emission Test Systems Gmbh Device for determining the concentration of at least one gas in a sample gas stream
TWI627393B (en) * 2012-07-25 2018-06-21 提拉諾斯股份有限公司 Cuvette
US9513224B2 (en) 2013-02-18 2016-12-06 Theranos, Inc. Image analysis and measurement of biological samples
US9113570B2 (en) * 2012-10-31 2015-08-18 Tyco Electronics Services Gmbh Planar electronic device having a magnetic component
US10036709B2 (en) * 2014-05-20 2018-07-31 Roche Diabetes Care, Inc. BG meter illuminated test strip
EP3175222B1 (en) * 2014-07-29 2019-08-21 Ldip, Llc Device for detecting a level of an analyte in a sample
US11181479B2 (en) 2015-02-27 2021-11-23 Ldip, Llc Waveguide-based detection system with scanning light source
US10823661B2 (en) 2015-08-18 2020-11-03 University Of Cincinnati Analyte sensor and method of use
US10768105B1 (en) 2016-07-29 2020-09-08 Labrador Diagnostics Llc Image analysis and measurement of biological samples
US10974241B2 (en) 2017-03-30 2021-04-13 TE Connectivity Services Gmbh Fluid sensing system
DE102018202591A1 (en) * 2018-02-21 2019-08-22 Robert Bosch Gmbh Optical system and method of making an optical system
DE102018118110B4 (en) * 2018-07-26 2023-01-05 OSRAM Opto Semiconductors Gesellschaft mit beschränkter Haftung SENSING DEVICE AND METHOD OF MAKING SENSING DEVICE

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6176962B1 (en) * 1990-02-28 2001-01-23 Aclara Biosciences, Inc. Methods for fabricating enclosed microchannel structures
US6054034A (en) * 1990-02-28 2000-04-25 Aclara Biosciences, Inc. Acrylic microchannels and their use in electrophoretic applications
US5858188A (en) * 1990-02-28 1999-01-12 Aclara Biosciences, Inc. Acrylic microchannels and their use in electrophoretic applications
US5046800A (en) * 1990-10-09 1991-09-10 At&T Bell Laboratories Article comprising a passive optical waveguide
US5313545A (en) * 1993-02-19 1994-05-17 Motorola, Inc. Molded waveguide with a unitary cladding region and method of making
SE9304145D0 (en) * 1993-12-10 1993-12-10 Pharmacia Lkb Biotech Ways to manufacture cavity structures
US5644395A (en) * 1995-07-14 1997-07-01 Regents Of The University Of California Miniaturized flow injection analysis system
DE19642088A1 (en) * 1996-10-12 1998-04-16 Bosch Gmbh Robert Manufacturing a micro:textured component
US6788862B2 (en) * 2002-05-14 2004-09-07 Corning, Inc. Microstructured optical waveguide having large optical nonlinearity

Also Published As

Publication number Publication date
EP1292822A1 (en) 2003-03-19
WO2001098759A1 (en) 2001-12-27
JP2004501372A (en) 2004-01-15
DE10029946A1 (en) 2001-12-20
US20030161572A1 (en) 2003-08-28

Similar Documents

Publication Publication Date Title
AU2001281782A1 (en) Integrated optical waveguides for microfluidic analysis systems
AU2001268283A1 (en) Optical inspection system
AU2002310130A1 (en) Lensed tapered optical waveguide
AU2001286511A1 (en) Optical devices with fluidic systems
AU2001271389A1 (en) Optical system
AU2001268062A1 (en) Multi-channel optical transceiver
AU2002326550A1 (en) Precision fiber ferrules
AU2001214889A1 (en) Athermalized integrated optical waveguide devices
AU2002222182A1 (en) Fibre optic sensor systems
AU2001285043A1 (en) Fiber-optic waveguides for transverse optical coupling
AU2001290279A1 (en) Optical device
AU3444799A (en) Integrated optical lightguide device
AU2001294664A1 (en) Optical inspection system having integrated component learning
EP1258766A3 (en) Optical system for shape measurement
AU2002319132A1 (en) Splicing device for splicing optical waveguides
EP1273936A3 (en) Optical waveguide
AU2002216982A1 (en) Reverse symmetry waveguide for optical biosensing
AU2001277626A1 (en) Integrated optical device
AU2001235818A1 (en) Integrated optical device
AU2002220827A1 (en) Integrated optical waveguide device
AU2001290695A1 (en) Optical conduit
AU2001252933A1 (en) Symmetric optical analysis device
AU2001275731A1 (en) An optical waveguide
AU2001244100A1 (en) Method for the optical analysis of a fluid
AU2002352287A1 (en) Device for transporting optical fibre