AU2001275378A1 - Methods and compositions for inhibiting immunoglobulin-mediated reperfusion inj ury - Google Patents

Methods and compositions for inhibiting immunoglobulin-mediated reperfusion inj ury

Info

Publication number
AU2001275378A1
AU2001275378A1 AU2001275378A AU7537801A AU2001275378A1 AU 2001275378 A1 AU2001275378 A1 AU 2001275378A1 AU 2001275378 A AU2001275378 A AU 2001275378A AU 7537801 A AU7537801 A AU 7537801A AU 2001275378 A1 AU2001275378 A1 AU 2001275378A1
Authority
AU
Australia
Prior art keywords
methods
compositions
immunoglobulin
mediated reperfusion
inj ury
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001275378A
Inventor
Michael C. Carroll
Herbert B. Hechtman
Francis D. Moore Jr.
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Immune Disease Institute Inc
Original Assignee
BLOOD RES CENTER
Immune Disease Institute Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by BLOOD RES CENTER, Immune Disease Institute Inc filed Critical BLOOD RES CENTER
Publication of AU2001275378A1 publication Critical patent/AU2001275378A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/52—Constant or Fc region; Isotype

Abstract

Methods and compositions for treating or preventing immunoglobulin-mediated reperfusion or ischemic injury, in a subject, are provided. Methods for identifying inhibitors of an interaction between a pathogenic immunoglobulin and an ischemic antigen or a component of the complement pathway are provided. Pathogenic immunoglobulins and mutated forms thereof are also disclosed.
AU2001275378A 2000-06-08 2001-06-08 Methods and compositions for inhibiting immunoglobulin-mediated reperfusion inj ury Abandoned AU2001275378A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US21027200P 2000-06-08 2000-06-08
US60210272 2000-06-08
PCT/US2001/018510 WO2001093892A1 (en) 2000-06-08 2001-06-08 Methods and compositions for inhibiting immunoglobulin-mediated__reperfusion injury

Publications (1)

Publication Number Publication Date
AU2001275378A1 true AU2001275378A1 (en) 2001-12-17

Family

ID=22782260

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001275378A Abandoned AU2001275378A1 (en) 2000-06-08 2001-06-08 Methods and compositions for inhibiting immunoglobulin-mediated reperfusion inj ury

Country Status (9)

Country Link
EP (2) EP2251026A1 (en)
JP (1) JP2004502412A (en)
CN (1) CN1443074A (en)
AT (1) ATE459367T1 (en)
AU (1) AU2001275378A1 (en)
CA (1) CA2410458A1 (en)
DE (1) DE60141463D1 (en)
ES (1) ES2343351T3 (en)
WO (1) WO2001093892A1 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20100136684A1 (en) * 2004-03-01 2010-06-03 Carroll Michael C Natural IgM Antibodies
JP5557982B2 (en) * 2004-03-01 2014-07-23 イミューン ディズィーズ インスティテュート インコーポレイテッド Natural IgM antibodies and inhibitors thereof
AU2012200909B2 (en) * 2004-03-01 2013-10-03 Immune Disease Institute, Inc Natural lgM antibodies and inhibitors thereof
WO2009035055A1 (en) * 2007-09-14 2009-03-19 Juridical Foundation The Chemo-Sero-Therapeutic Research Institute Insulin-like growth factor-1 (igf-1) production promoter

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EP0173494A3 (en) 1984-08-27 1987-11-25 The Board Of Trustees Of The Leland Stanford Junior University Chimeric receptors by dna splicing and expression
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DE768377T1 (en) 1988-09-02 1998-01-02 Dyax Corp Production and selection of recombinant proteins with different binding sites
US5530101A (en) 1988-12-28 1996-06-25 Protein Design Labs, Inc. Humanized immunoglobulins
WO1991000906A1 (en) 1989-07-12 1991-01-24 Genetics Institute, Inc. Chimeric and transgenic animals capable of producing human antibodies
JPH05501611A (en) 1989-11-13 1993-03-25 アフィマックス　テクノロジーズ　ナームロゼ　ベノートスハップ Spatially addressable immobilization of antiligands on surfaces
DE69120146T2 (en) 1990-01-12 1996-12-12 Cell Genesys Inc GENERATION OF XENOGENIC ANTIBODIES
US5427908A (en) 1990-05-01 1995-06-27 Affymax Technologies N.V. Recombinant library screening methods
DK0585287T3 (en) 1990-07-10 2000-04-17 Cambridge Antibody Tech Process for producing specific binding pair elements
GB9015198D0 (en) 1990-07-10 1990-08-29 Brien Caroline J O Binding substance
ES2246502T3 (en) 1990-08-29 2006-02-16 Genpharm International, Inc. TRANSGENIC NON-HUMAN ANIMALS ABLE TO PRODUCE HETEROLOGICAL ANTIBODIES.
WO1992003917A1 (en) 1990-08-29 1992-03-19 Genpharm International Homologous recombination in mammalian cells
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EP0562025B1 (en) 1990-12-06 2001-02-07 Affymetrix, Inc. (a Delaware Corporation) Compounds and their use in a binary synthesis strategy
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DE4122599C2 (en) 1991-07-08 1993-11-11 Deutsches Krebsforsch Phagemid for screening antibodies
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US5359115A (en) 1992-03-26 1994-10-25 Affymax Technologies, N.V. Methods for the synthesis of phosphonate esters
US5573905A (en) 1992-03-30 1996-11-12 The Scripps Research Institute Encoded combinatorial chemical libraries
US5288514A (en) 1992-09-14 1994-02-22 The Regents Of The University Of California Solid phase and combinatorial synthesis of benzodiazepine compounds on a solid support
DE69333087T2 (en) 1992-10-01 2004-05-06 The Trustees Of Columbia University In The City Of New York COMPLEX COMBINATORY CHEMICAL BANKS WITH MARKINGS
JPH08511420A (en) 1993-06-16 1996-12-03 セルテック・セラピューテイクス・リミテッド Body
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JPH11505704A (en) * 1995-05-17 1999-05-25 リージェンツ・オブ・ザ・ユニバーシティ・オブ・ミネソタ Immunoconjugates Containing Single Chain Variable Region Fragments of Anti-CD-19 Antibodies
IT1395574B1 (en) 2009-09-14 2012-10-16 Guala Dispensing Spa DISTRIBUTION DEVICE

Also Published As

Publication number Publication date
DE60141463D1 (en) 2010-04-15
WO2001093892A1 (en) 2001-12-13
EP1286682A1 (en) 2003-03-05
ATE459367T1 (en) 2010-03-15
EP1286682B1 (en) 2010-03-03
EP2251026A1 (en) 2010-11-17
CA2410458A1 (en) 2001-12-13
CN1443074A (en) 2003-09-17
JP2004502412A (en) 2004-01-29
ES2343351T3 (en) 2010-07-29
EP1286682A4 (en) 2004-10-13

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