AU2001267091A1 - Transdifferentiation of glial cells - Google Patents

Transdifferentiation of glial cells

Info

Publication number
AU2001267091A1
AU2001267091A1 AU2001267091A AU6709101A AU2001267091A1 AU 2001267091 A1 AU2001267091 A1 AU 2001267091A1 AU 2001267091 A AU2001267091 A AU 2001267091A AU 6709101 A AU6709101 A AU 6709101A AU 2001267091 A1 AU2001267091 A1 AU 2001267091A1
Authority
AU
Australia
Prior art keywords
transdifferentiation
glial cells
glial
cells
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001267091A
Inventor
Tuiga Helina Salin-Nordstrom
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Spinal Cord Society
Original Assignee
SPINAL CORD SOC
Spinal Cord Society
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SPINAL CORD SOC, Spinal Cord Society filed Critical SPINAL CORD SOC
Publication of AU2001267091A1 publication Critical patent/AU2001267091A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0618—Cells of the nervous system
    • C12N5/0623—Stem cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/115—Basic fibroblast growth factor (bFGF, FGF-2)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/13—Nerve growth factor [NGF]; Brain-derived neurotrophic factor [BDNF]; Cilliary neurotrophic factor [CNTF]; Glial-derived neurotrophic factor [GDNF]; Neurotrophins [NT]; Neuregulins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
    • C12N2506/08—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from cells of the nervous system
AU2001267091A 2000-06-16 2001-06-14 Transdifferentiation of glial cells Abandoned AU2001267091A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US21224000P 2000-06-16 2000-06-16
US60/212,240 2000-06-16
US09/644,498 2000-08-23
US09/644,498 US6897061B1 (en) 2000-06-16 2000-08-23 Transdifferentiation of glial cells
PCT/US2001/040971 WO2001095861A2 (en) 2000-06-16 2001-06-14 Transdifferentiation of glial cells

Publications (1)

Publication Number Publication Date
AU2001267091A1 true AU2001267091A1 (en) 2001-12-24

Family

ID=26906932

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001267091A Abandoned AU2001267091A1 (en) 2000-06-16 2001-06-14 Transdifferentiation of glial cells

Country Status (3)

Country Link
US (2) US6897061B1 (en)
AU (1) AU2001267091A1 (en)
WO (1) WO2001095861A2 (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001088103A2 (en) * 2000-05-12 2001-11-22 University Of Utah Research Foundation Compositions and methods for tissue dedifferentiation and regeneration
US20040087016A1 (en) * 2000-05-12 2004-05-06 University Of Utah Research Foundation Compositions and methods for cell dedifferentiation and tissue regeneration
US20080226609A1 (en) * 2005-08-26 2008-09-18 University Of Rochester Transplantation of Glial Restricted Precursor-Derived Astrocytes for Promotion of Axon Growth
KR100794359B1 (en) * 2006-02-27 2008-01-15 주식회사 임젠 De-differentiation of astrocytes into neural stem cell using Shh
CN101389761A (en) * 2006-02-27 2009-03-18 银怎株式会社 De-differentiation of astrocytes into neural stem cell using bmi-1
KR101793722B1 (en) * 2014-08-25 2017-11-03 한국생명공학연구원 Process for preparing astrocyte
WO2019073055A1 (en) 2017-10-13 2019-04-18 Imba - Institut Für Molekulare Biotechnologie Gmbh Enhanced reprogramming of somatic cells
KR20230123926A (en) * 2020-09-29 2023-08-24 뉴엑셀 테라퓨틱스 아이엔씨. DLX2 vectors

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US32181A (en) * 1861-04-30 Boot and pantaloon jack
US4444760A (en) 1983-06-17 1984-04-24 Merck & Co., Inc. Purification and characterization of a protein fibroblast growth factor
US5439818A (en) 1985-09-12 1995-08-08 Scios Nova Inc. DNA encoding human recombinant basic fibroblast growth factor
US5082670A (en) 1988-12-15 1992-01-21 The Regents Of The University Of California Method of grafting genetically modified cells to treat defects, disease or damage or the central nervous system
US5650148A (en) 1988-12-15 1997-07-22 The Regents Of The University Of California Method of grafting genetically modified cells to treat defects, disease or damage of the central nervous system
US5411883A (en) 1989-12-26 1995-05-02 Somatix Therapy Corporation Proliferated neuron progenitor cell product and process
US5618531A (en) 1990-10-19 1997-04-08 New York University Method for increasing the viability of cells which are administered to the brain or spinal cord
US6071889A (en) 1991-07-08 2000-06-06 Neurospheres Holdings Ltd. In vivo genetic modification of growth factor-responsive neural precursor cells
US5980885A (en) 1991-07-08 1999-11-09 Neurospheres Holdings Ltd. Growth factor-induced proliferation of neural precursor cells in vivo
US5981165A (en) 1991-07-08 1999-11-09 Neurospheres Holdings Ltd. In vitro induction of dopaminergic cells
US6497872B1 (en) 1991-07-08 2002-12-24 Neurospheres Holdings Ltd. Neural transplantation using proliferated multipotent neural stem cells and their progeny
US5851832A (en) 1991-07-08 1998-12-22 Neurospheres, Ltd. In vitro growth and proliferation of multipotent neural stem cells and their progeny
US5750376A (en) 1991-07-08 1998-05-12 Neurospheres Holdings Ltd. In vitro growth and proliferation of genetically modified multipotent neural stem cells and their progeny
EP1329499A3 (en) 1991-07-08 2003-09-03 Neurospheres Holdings Ltd. Growth factor-responsive progenitor cells which can be proliferated in vitro
US5792900A (en) 1991-10-21 1998-08-11 The Trustees Of The University Of Pennsylvania Compositions and methods for producing and using homogenous neuronal cell transplants
US5175103A (en) 1991-10-21 1992-12-29 Trustees Of University Of Pennsylvania Preparation of pure cultures of post-mitotic human neurons
US5589376A (en) 1992-07-27 1996-12-31 California Institute Of Technology Mammalian neural crest stem cells
US5654183A (en) 1992-07-27 1997-08-05 California Institute Of Technology Genetically engineered mammalian neural crest stem cells
US5928947A (en) 1992-07-27 1999-07-27 California Institute Of Technology Mammalian multipotent neural stem cells
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US5589375A (en) 1992-10-06 1996-12-31 Max-Planck-Gesellschaft Zur Forderung Der Wissenschaften E. V. PTP 1D: a novel protein tyrosine phosphatase
US6033906A (en) 1993-07-26 2000-03-07 California Institute Of Technology Methods for differentiating neural stem cells to glial cells using neuregulins
US6001654A (en) 1994-01-28 1999-12-14 California Institute Of Technology Methods for differentiating neural stem cells to neurons or smooth muscle cells using TGT-β super family growth factors
US5753505A (en) 1995-07-06 1998-05-19 Emory University Neuronal progenitor cells and uses thereof
US6184200B1 (en) 1995-09-28 2001-02-06 Amgen Inc. Truncated glial cell line-derived neurotrophic factor
US5753506A (en) * 1996-05-23 1998-05-19 Cns Stem Cell Technology, Inc. Isolation propagation and directed differentiation of stem cells from embryonic and adult central nervous system of mammals
US6361996B1 (en) * 1997-05-07 2002-03-26 University Of Utah Research Foundation Neuroepithelial stem cells and glial-restricted intermediate precursors
US6235527B1 (en) * 1997-11-29 2001-05-22 University Of Utah Research Foundation Lineage restricted glial precursors from the central nervous system
US5968829A (en) 1997-09-05 1999-10-19 Cytotherapeutics, Inc. Human CNS neural stem cells
US6071691A (en) 1998-04-27 2000-06-06 Oregon Health Science University Materials and methods for modulating differentiation
US5958767A (en) 1998-08-14 1999-09-28 The Children's Medical Center Corp. Engraftable human neural stem cells
US6087168A (en) 1999-01-20 2000-07-11 Cedars Sinai Medical Center Conversion of non-neuronal cells into neurons: transdifferentiation of epidermal cells
US7621606B2 (en) * 2001-08-27 2009-11-24 Advanced Cell Technology, Inc. Trans-differentiation and re-differentiation of somatic cells and production of cells for cell therapies
AU2001286506A1 (en) 2000-08-16 2002-02-25 The University Of Tennessee Research Corporation Isolated mammalian neural stem cells, methods of making such cells, and methods of using such cells
CA2364095C (en) * 2001-07-20 2011-07-12 Neurostasis, Inc Production of radial glial cells

Also Published As

Publication number Publication date
US20050265981A1 (en) 2005-12-01
WO2001095861A3 (en) 2003-05-15
WO2001095861A2 (en) 2001-12-20
US6897061B1 (en) 2005-05-24

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