AU2001230192A1 - Method for the enzymatic resolution of the racemates of aminomethyl-aryl-cyclohexanol derivatives - Google Patents

Method for the enzymatic resolution of the racemates of aminomethyl-aryl-cyclohexanol derivatives

Info

Publication number: AU2001230192A1
Authority: AU; Australia
Prior art keywords: racemates; aminomethyl; aryl; enzymatic resolution; cyclohexanol derivatives
Prior art date: 2000-02-04
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Granted

Application number

AU2001230192A

Other versions

AU2001230192B2 (en

Inventor

Helmut Buschmann

Hans-Joachim Gais

Carsten Griebel

Dagmar Kaulartz

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Gruenenthal GmbH

Original Assignee

Gruenenthal GmbH

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-02-04

Filing date

2001-01-18

Publication date

2001-10-25

2000-02-04 Priority claimed from DE10004926A external-priority patent/DE10004926A1/en

2001-01-18 Application filed by Gruenenthal GmbH filed Critical Gruenenthal GmbH

2001-10-25 Publication of AU2001230192A1 publication Critical patent/AU2001230192A1/en

2006-07-13 Application granted granted Critical

2006-07-13 Publication of AU2001230192B2 publication Critical patent/AU2001230192B2/en

2021-01-18 Anticipated expiration legal-status Critical

Status Ceased legal-status Critical Current

Links

230000002255 enzymatic Effects 0.000 title 1

AU2001230192A 2000-02-04 2001-01-18 Method for the enzymatic resolution of the racemates of aminomethyl-aryl-cyclohexanol derivatives Ceased AU2001230192B2 (en)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
DE10004926A DE10004926A1 (en)	2000-02-04	2000-02-04	Process for the enzymatic resolution of aminomethyl aryl cyclohexanol derivatives
DE10004926.5		2000-02-04
PCT/EP2001/000522 WO2001057232A1 (en)	2000-02-04	2001-01-18	Method for the enzymatic resolution of the racemates of aminomethyl-aryl-cyclohexanol derivatives

Publications (2)

Publication Number	Publication Date
AU2001230192A1 true AU2001230192A1 (en)	2001-10-25
AU2001230192B2 AU2001230192B2 (en)	2006-07-13

Family

ID=7629816

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
AU2001230192A Ceased AU2001230192B2 (en)	2000-02-04	2001-01-18	Method for the enzymatic resolution of the racemates of aminomethyl-aryl-cyclohexanol derivatives
AU3019201A Pending AU3019201A (en)	2000-02-04	2001-01-18	Method for the enzymatic resolution of the racemates of aminomethyl-aryl-cyclohexanol derivatives

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
AU3019201A Pending AU3019201A (en)	2000-02-04	2001-01-18	Method for the enzymatic resolution of the racemates of aminomethyl-aryl-cyclohexanol derivatives

Country Status (21)

Country	Link
US (1)	US7168937B2 (en)
EP (1)	EP1252327B1 (en)
JP (1)	JP2003528049A (en)
AR (1)	AR027327A1 (en)
AT (1)	ATE274599T1 (en)
AU (2)	AU2001230192B2 (en)
CA (1)	CA2399819C (en)
CO (1)	CO5271656A1 (en)
DE (2)	DE10004926A1 (en)
DK (1)	DK1252327T3 (en)
ES (1)	ES2227118T3 (en)
HK (1)	HK1051558A1 (en)
HU (1)	HUP0204430A3 (en)
MX (1)	MXPA02007594A (en)
NZ (1)	NZ521087A (en)
PE (1)	PE20011075A1 (en)
PT (1)	PT1252327E (en)
SI (1)	SI1252327T1 (en)
TR (1)	TR200402470T4 (en)
UY (1)	UY26574A1 (en)
WO (1)	WO2001057232A1 (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE10049481A1 (en) *	2000-09-29	2002-05-02	Gruenenthal Gmbh	Substituted C-cyclohexylmethylamine derivatives
DE10059413A1 (en)	2000-11-30	2002-06-20	Gruenenthal Gmbh	Use of substituted 6-dimethylaminomethyl-1-phenyl-cyclohexane compounds for the treatment of urinary incontinence
EP1908460A1 (en)	2002-11-22	2008-04-09	Grünenthal GmbH	Use of (1R, 2R)-3-(2-dimethyl amino methyl-cyclohexyl) phenol for treating painful inflammations
DE10308350B4 (en) *	2003-02-27	2006-06-01	Sanofi-Aventis Deutschland Gmbh	Process for preparing the enantiomeric forms of cis-configured 1,3-cyclohexanediol derivatives
US7094795B2 (en)	2003-02-27	2006-08-22	Sanofi-Aventis Deutschland Gmbh	Process for preparing the enantiomeric forms of cis-configured 1,3-cyclohexanediol derivatives
DE102004038403B4 (en) *	2004-08-07	2006-08-31	Sanofi-Aventis Deutschland Gmbh	Process for preparing the enantiomeric forms of cis-configured 3-hydroxycyclohexanecarboxylic acid derivatives
US20060211887A1 (en) *	2005-02-25	2006-09-21	Gruenenthal Gmbh	Phosphate salts of 6-dimethylaminomethyl-1-(3-methoxyphenyl)-1,3-dihydroxy-cyclohexane compounds
DE102007022790A1 (en)	2007-05-11	2008-11-20	Grünenthal GmbH	Axomadol for the treatment of pain in osteoarthritis

Family Cites Families (15)

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Publication number	Priority date	Publication date	Assignee	Title
IN162851B (en) *	1980-09-19	1988-07-16	Pfizer
JP3049403B2 (en)	1991-11-01	2000-06-05	チッソ株式会社	Optically active trans-2-aryl-1-cyclohexanol derivative and method for producing the same
CA2068038A1 (en)	1991-05-08	1992-11-09	Christopher Yee	Enzymatic resolution of .alpha.-tertiary carboxylic acid esters
ATE195973T1 (en) *	1992-01-15	2000-09-15	Squibb & Sons Inc	ENZYMATIC PROCESS FOR THE RESOLUTION OF ENANTIOMER MIXTURES USEFUL AS INTERMEDIATE PRODUCTS FOR THE PRODUCTION OF TAXANES
DE4217506A1 (en)	1992-05-27	1993-12-02	Boehringer Mannheim Gmbh	Microbial esterase for the enantioselective cleavage of 1-arylalkyl esters
ES2046950B1 (en)	1992-06-08	1994-10-01	Menarini Lab	PROCESS FOR THE PRODUCTION OF ACID S - (+) - 2- (3-BENZOILFENIL) PROPIONICO BY ENZYMATICALLY CATALYZED ENANTIOUS HYDROLYSIS.
JPH07101921A (en)	1993-10-01	1995-04-18	Chisso Corp	Optically active trifluoromethylbenzyl alcohol derivative and its production
DE4414273A1 (en)	1994-04-23	1995-10-26	Chemie Linz Deutschland	Optical resolution of racemic alcohols
US5696299A (en)	1994-10-26	1997-12-09	The Nisshin Oil Mills, Ltd.	Optical resolution for producing optically active alcohol
US5770438A (en) *	1994-11-01	1998-06-23	Takeda Chemical Industries, Ltd.	Process for enantioselective hydrolysis of α-(2-amino)-phenyl-benzenemethanol ester type compounds using bacillus, pseudomonas or streptomyces
JPH08322590A (en)	1995-06-05	1996-12-10	Chisso Corp	Optically active 2-(1-naphthyl)cyclohexan-1-ol derivative and its production
DE19525137C2 (en) *	1995-07-11	2003-02-27	Gruenenthal Gmbh	6-Dimethylaminomethyl-1-phenyl-cyclohexane compounds as intermediates for the preparation of pharmaceutical agents
JPH09121564A (en)	1995-10-27	1997-05-06	Kasei Optonix Co Ltd	Electrostatic actuator
DE19547766A1 (en)	1995-12-20	1997-06-26	Gruenenthal Gmbh	1-phenyl-2-dimethylaminomethyl-cyclohexan-1-ol compounds as active pharmaceutical ingredients
WO1998040053A1 (en) *	1997-03-11	1998-09-17	Darwin Discovery Limited	Dosage forms comprising separate portions of r- and s-enantiomers

2000
- 2000-02-04 DE DE10004926A patent/DE10004926A1/en not_active Ceased
2001
- 2001-01-18 DE DE50103394T patent/DE50103394D1/en not_active Expired - Lifetime
- 2001-01-18 US US10/203,031 patent/US7168937B2/en not_active Expired - Fee Related
- 2001-01-18 WO PCT/EP2001/000522 patent/WO2001057232A1/en active IP Right Grant
- 2001-01-18 TR TR2004/02470T patent/TR200402470T4/en unknown
- 2001-01-18 JP JP2001558044A patent/JP2003528049A/en active Pending
- 2001-01-18 ES ES01902333T patent/ES2227118T3/en not_active Expired - Lifetime
- 2001-01-18 HU HU0204430A patent/HUP0204430A3/en unknown
- 2001-01-18 PT PT01902333T patent/PT1252327E/en unknown
- 2001-01-18 AU AU2001230192A patent/AU2001230192B2/en not_active Ceased
- 2001-01-18 CA CA2399819A patent/CA2399819C/en not_active Expired - Fee Related
- 2001-01-18 EP EP01902333A patent/EP1252327B1/en not_active Expired - Lifetime
- 2001-01-18 MX MXPA02007594A patent/MXPA02007594A/en active IP Right Grant
- 2001-01-18 AT AT01902333T patent/ATE274599T1/en active
- 2001-01-18 SI SI200130183T patent/SI1252327T1/en unknown
- 2001-01-18 NZ NZ521087A patent/NZ521087A/en not_active IP Right Cessation
- 2001-01-18 DK DK01902333T patent/DK1252327T3/en active
- 2001-01-18 AU AU3019201A patent/AU3019201A/en active Pending
- 2001-01-30 AR ARP010100415A patent/AR027327A1/en active IP Right Grant
- 2001-02-01 PE PE2001000115A patent/PE20011075A1/en not_active Application Discontinuation
- 2001-02-02 CO CO01007847A patent/CO5271656A1/en not_active Application Discontinuation
- 2001-02-02 UY UY26574A patent/UY26574A1/en not_active Application Discontinuation
2003
- 2003-04-30 HK HK03103081A patent/HK1051558A1/en not_active IP Right Cessation

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