ATE368665T1
(en)
|
1997-08-22 |
2007-08-15 |
Astrazeneca Ab |
OXINDOLYLQUINAZOLINE DERIVATIVES AS ANGIOGENESIS INHIBITORS
|
US7262201B1
(en)
*
|
1998-10-08 |
2007-08-28 |
Astrazeneca Ab |
Quinazoline derivatives
|
GB2345486A
(en)
*
|
1999-01-11 |
2000-07-12 |
Glaxo Group Ltd |
Heteroaromatic protein tyrosine kinase inhibitors
|
EP2298311B1
(en)
|
1999-01-13 |
2012-05-09 |
Bayer HealthCare LLC |
w-Carboxy aryl substituted diphenyl ureas as p38 kinase inhibitors
|
US8124630B2
(en)
|
1999-01-13 |
2012-02-28 |
Bayer Healthcare Llc |
ω-carboxyaryl substituted diphenyl ureas as raf kinase inhibitors
|
CZ306810B6
(en)
|
1999-02-10 |
2017-07-19 |
Astrazeneca Ab |
The use of a quinazoline derivative as an inhibitor of angiogenesis
|
US6933299B1
(en)
|
1999-07-09 |
2005-08-23 |
Smithkline Beecham Corporation |
Anilinoquinazolines as protein tyrosine kinase inhibitors
|
JP2003504363A
(en)
|
1999-07-09 |
2003-02-04 |
グラクソ グループ リミテッド |
Anilinoquinazolines as protein tyrosine kinase inhibitors
|
RU2002110461A
(en)
*
|
1999-09-21 |
2004-03-10 |
Астразенека Аб (Se) |
Quinazoline derivatives and their use as pharmaceutical substances
|
GB9922171D0
(en)
|
1999-09-21 |
1999-11-17 |
Zeneca Ltd |
Chemical compounds
|
UA74803C2
(en)
|
1999-11-11 |
2006-02-15 |
Осі Фармасьютікалз, Інк. |
A stable polymorph of n-(3-ethynylphenyl)-6,7-bis(2-methoxyetoxy)-4-quinazolinamine hydrochloride, a method for producing thereof (variants) and pharmaceutical use
|
WO2001055116A2
(en)
*
|
2000-01-28 |
2001-08-02 |
Astrazeneca Ab |
Quinoline derivatives and their use as aurora 2 kinase inhibitors
|
CA2413424C
(en)
|
2000-06-22 |
2007-10-02 |
Pfizer Products Inc. |
Substituted bicyclic derivatives for the treatment of abnormal cell growth
|
SK18102002A3
(en)
*
|
2000-06-28 |
2003-07-01 |
Astrazeneca Ab |
Substituted quinazoline derivatives, their use and a composition comprising said derivatives
|
US7371765B2
(en)
|
2000-08-09 |
2008-05-13 |
Astrazeneca Ab |
Quinoline derivatives having VEGF inhibiting activity
|
AU2001293817A1
(en)
|
2000-09-20 |
2002-04-02 |
Merck Patent Gmbh |
4-amino-quinazolines
|
ES2318649T3
(en)
|
2000-10-20 |
2009-05-01 |
EISAI R&D MANAGEMENT CO., LTD. |
PROCEDURE FOR PREPARATION OF DERIVATIVES OF 4-FENOXI QUINOLINAS.
|
AR032028A1
(en)
|
2001-01-05 |
2003-10-22 |
Pfizer |
ANTIBODIES AGAINST THE RECEIVER OF THE SIMILAR TO INSULIN GROWTH FACTOR
|
AU2002245709A1
(en)
*
|
2001-03-23 |
2002-10-08 |
Bayer Corporation |
Rho-kinase inhibitors
|
AR035791A1
(en)
*
|
2001-03-23 |
2004-07-14 |
Bayer Corp |
COMPOUND N, N-DIHETEROCICLICO OF AMINA, INHIBITOR OF THE RHO-KINASE, ITS USE FOR THE MANUFACTURE OF A MEDICINAL PRODUCT AND PROCESS FOR THE PREPARATION OF THE COMPOUND
|
ES2263743T3
(en)
|
2001-04-13 |
2006-12-16 |
Pfizer Products Inc. |
DERIVATIVES OF 4-AMINOPIRIDOPIRIMIDINE REPLACED WITH A BICYCLE GROUP.
|
WO2003000194A2
(en)
|
2001-06-21 |
2003-01-03 |
Pfizer Inc. |
Thienopyridine and thienopyrimidine anticancer agents
|
US7829566B2
(en)
|
2001-09-17 |
2010-11-09 |
Werner Mederski |
4-amino-quinazolines
|
AR039067A1
(en)
|
2001-11-09 |
2005-02-09 |
Pfizer Prod Inc |
ANTIBODIES FOR CD40
|
AU2003202263A1
(en)
|
2002-01-10 |
2003-07-30 |
Bayer Healthcare Ag |
Roh-kinase inhibitors
|
CA2473510A1
(en)
|
2002-01-23 |
2003-07-31 |
Bayer Pharmaceuticals Corporation |
Pyrimidine derivatives as rho-kinase inhibitors
|
US6943172B2
(en)
|
2002-01-23 |
2005-09-13 |
Bayer Pharmaceuticals Corporation |
Rho-kinase inhibitors
|
US7268230B2
(en)
*
|
2002-02-01 |
2007-09-11 |
Astrazeneca Ab |
Quinazoline compounds
|
MXPA04007832A
(en)
|
2002-02-11 |
2005-09-08 |
Bayer Pharmaceuticals Corp |
Aryl ureas with angiogenesis inhibiting activity.
|
US6924285B2
(en)
|
2002-03-30 |
2005-08-02 |
Boehringer Ingelheim Pharma Gmbh & Co. |
Bicyclic heterocyclic compounds, pharmaceutical compositions containing these compounds, their use and process for preparing them
|
UA77303C2
(en)
|
2002-06-14 |
2006-11-15 |
Pfizer |
Derivatives of thienopyridines substituted by benzocondensed heteroarylamide useful as therapeutic agents, pharmaceutical compositions and methods for their use
|
JP3814285B2
(en)
|
2002-12-19 |
2006-08-23 |
ファイザー・インク |
2- (1H-indazol-6-ylamino) -benzamide compounds as protein kinase inhibitors useful in the treatment of eye diseases
|
GEP20084341B
(en)
|
2003-02-26 |
2008-03-25 |
Sugen Inc |
Aminoheteroaryl compounds as protein kinase inhibitors
|
GB0309850D0
(en)
|
2003-04-30 |
2003-06-04 |
Astrazeneca Ab |
Quinazoline derivatives
|
CA2526617C
(en)
|
2003-05-20 |
2015-04-28 |
Bayer Pharmaceuticals Corporation |
Diaryl ureas with kinase inhibiting activity
|
DE602004017479D1
(en)
|
2003-08-29 |
2008-12-11 |
Pfizer |
THIENOPYRIDINPHENYLACETAMIDES SUITED AS NEW ANTIANGIOGENIC AGENTS AND DERIVATIVES THEREOF
|
AR045563A1
(en)
|
2003-09-10 |
2005-11-02 |
Warner Lambert Co |
ANTIBODIES DIRECTED TO M-CSF
|
WO2005026156A1
(en)
*
|
2003-09-16 |
2005-03-24 |
Astrazeneca Ab |
Quinazoline derivatives
|
SI1667991T1
(en)
|
2003-09-16 |
2008-10-31 |
Astrazeneca Ab |
Quinazoline derivatives as tyrosine kinase inhibitors
|
GB0322409D0
(en)
|
2003-09-25 |
2003-10-29 |
Astrazeneca Ab |
Quinazoline derivatives
|
CN101337930B
(en)
|
2003-11-11 |
2010-09-08 |
卫材R&D管理有限公司 |
Urea derivative preparation process
|
GB0326459D0
(en)
|
2003-11-13 |
2003-12-17 |
Astrazeneca Ab |
Quinazoline derivatives
|
GB0330002D0
(en)
|
2003-12-24 |
2004-01-28 |
Astrazeneca Ab |
Quinazoline derivatives
|
EA011402B1
(en)
|
2004-01-23 |
2009-02-27 |
Эмджен Инк. |
Nitrogen-containing heterocyclic compounds and pharmaceutical use thereof
|
AU2005207946A1
(en)
|
2004-01-23 |
2005-08-11 |
Amgen Inc. |
Quinoline quinazoline pyridine and pyrimidine counds and their use in the treatment of inflammation angiogenesis and cancer
|
EP1713781B1
(en)
|
2004-02-03 |
2008-11-05 |
AstraZeneca AB |
Quinazoline derivatives
|
EP1746999B1
(en)
|
2004-05-06 |
2011-11-16 |
Warner-Lambert Company LLC |
4-phenylamino-quinazolin-6-yl-amides
|
ATE463486T1
(en)
|
2004-08-26 |
2010-04-15 |
Pfizer |
ENANTIOMER PURE AMINOHETEROARYL COMPOUNDS AS PROTEIN KINASE INHIBITORS
|
US8969379B2
(en)
|
2004-09-17 |
2015-03-03 |
Eisai R&D Management Co., Ltd. |
Pharmaceutical compositions of 4-(3-chloro-4-(cyclopropylaminocarbonyl)aminophenoxy)-7=methoxy-6-quinolinecarboxide
|
EP1827434B1
(en)
|
2004-11-30 |
2014-01-15 |
Amgen Inc. |
Quinolines and quinazoline analogs and their use as medicaments for treating cancer
|
DE602005026865D1
(en)
|
2004-12-14 |
2011-04-21 |
Astrazeneca Ab |
PYRAZOLOPYRIMIDINE COMPOUNDS AS ANTITUM-MEANS
|
NZ562453A
(en)
|
2005-03-31 |
2010-04-30 |
Agensys Inc |
Antibodies and related molecules that bind to 161P2F10B proteins
|
BRPI0608096A2
(en)
|
2005-04-26 |
2009-11-10 |
Pfizer |
p-cadherin antibodies
|
JO2787B1
(en)
|
2005-04-27 |
2014-03-15 |
امجين إنك, |
Substituted Amid derivatives & methods of use
|
WO2007015578A1
(en)
|
2005-08-02 |
2007-02-08 |
Eisai R & D Management Co., Ltd. |
Method for assay on the effect of vascularization inhibitor
|
UA94060C2
(en)
|
2005-09-07 |
2011-04-11 |
Эмджен Фримонт Инк. |
Monoclonal antibodies that specifically binds alk-1
|
WO2007034144A1
(en)
|
2005-09-20 |
2007-03-29 |
Astrazeneca Ab |
4- (ih-indazol-s-yl-amino)-quinazoline compounds as erbb receptor tyrosine kinase inhibitors for the treatment of cancer
|
WO2007035744A1
(en)
|
2005-09-20 |
2007-03-29 |
Osi Pharmaceuticals, Inc. |
Biological markers predictive of anti-cancer response to insulin-like growth factor-1 receptor kinase inhibitors
|
CN101003514A
(en)
|
2006-01-20 |
2007-07-25 |
上海艾力斯医药科技有限公司 |
Derivative of quinazoline, preparation method and usage
|
EA200802058A1
(en)
|
2006-05-09 |
2009-06-30 |
Пфайзер Продактс Инк. |
DERIVATIVES OF CYCLO-ALKYLAMINO ACIDS AND THEIR PHARMACEUTICAL COMPOSITIONS
|
NL2000613C2
(en)
|
2006-05-11 |
2007-11-20 |
Pfizer Prod Inc |
Triazole pyrazine derivatives.
|
CA2652442C
(en)
|
2006-05-18 |
2014-12-09 |
Eisai R & D Management Co., Ltd. |
Antitumor agent for thyroid cancer
|
KR101472600B1
(en)
|
2006-08-28 |
2014-12-15 |
에자이 알앤드디 매니지먼트 가부시키가이샤 |
Antitumor agent for undifferentiated gastric cancer
|
SG174774A1
(en)
|
2006-09-11 |
2011-10-28 |
Curis Inc |
Quinazoline based egfr inhibitors containing a zinc binding moiety
|
US7547781B2
(en)
|
2006-09-11 |
2009-06-16 |
Curis, Inc. |
Quinazoline based EGFR inhibitors containing a zinc binding moiety
|
EP1921070A1
(en)
|
2006-11-10 |
2008-05-14 |
Boehringer Ingelheim Pharma GmbH & Co. KG |
Bicyclic heterocycles, medicaments comprising them, their use and process for their preparation
|
CA2676796C
(en)
|
2007-01-29 |
2016-02-23 |
Eisai R & D Management Co., Ltd. |
Composition for treatment of undifferentiated gastric cancer
|
AU2008212999A1
(en)
|
2007-02-06 |
2008-08-14 |
Boehringer Ingelheim International Gmbh |
Bicyclic heterocycles, drugs containing said compounds, use thereof, and method for production thereof
|
CN101245050A
(en)
*
|
2007-02-14 |
2008-08-20 |
上海艾力斯医药科技有限公司 |
4-aniline quinazoline derivative salt
|
JP5926487B2
(en)
|
2007-04-13 |
2016-05-25 |
デイナ ファーバー キャンサー インスティチュート,インコーポレイテッド |
Method for treating cancer resistant to ErbB therapy
|
PT2185574E
(en)
|
2007-09-07 |
2013-08-26 |
Agensys Inc |
Antibodies and related molecules that bind to 24p4c12 proteins
|
NZ585357A
(en)
|
2007-10-29 |
2012-02-24 |
Natco Pharma Ltd |
Novel 4-(tetrazol-5-yl)-quinazoline derivatives as anti cancer agents
|
CA2703257C
(en)
|
2007-10-29 |
2013-02-19 |
Amgen Inc. |
Benzomorpholine derivatives and methods of use
|
WO2009060945A1
(en)
|
2007-11-09 |
2009-05-14 |
Eisai R & D Management Co., Ltd. |
Combination of anti-angiogenic substance and anti-tumor platinum complex
|
ME01461B
(en)
|
2008-02-07 |
2014-04-20 |
Boehringer Ingelheim Int |
Spirocyclic heterocycles, medicaments containing said compounds, use thereof and method for their production
|
NZ589883A
(en)
|
2008-05-13 |
2012-06-29 |
Astrazeneca Ab |
Fumarate salt of 4- (3-chloro-2-fluoroanilino) -7-methoxy-6- { [1- (n-methylcarbamoylmethyl) piperidin- 4-yl] oxy} quinazoline
|
EP2313397B1
(en)
|
2008-08-08 |
2016-04-20 |
Boehringer Ingelheim International GmbH |
Cyclohexyloxy substituted heterocycles, medicine containing these connections, their application and production method
|
CA2737597C
(en)
|
2008-10-16 |
2017-03-14 |
University Of Pittsburgh-Of The Commonwealth System Of Higher Education |
Fully human antibodies to high molecular weight-melanoma associated antigen and uses thereof
|
WO2010054264A1
(en)
|
2008-11-07 |
2010-05-14 |
Triact Therapeutics, Inc. |
Use of catecholic butane derivatives in cancer therapy
|
SG172857A1
(en)
|
2009-02-09 |
2011-08-29 |
Supergen Inc |
Pyrrolopyrimidinyl axl kinase inhibitors
|
US20120189641A1
(en)
|
2009-02-25 |
2012-07-26 |
OSI Pharmaceuticals, LLC |
Combination anti-cancer therapy
|
WO2010099137A2
(en)
|
2009-02-26 |
2010-09-02 |
Osi Pharmaceuticals, Inc. |
In situ methods for monitoring the emt status of tumor cells in vivo
|
WO2010099363A1
(en)
|
2009-02-27 |
2010-09-02 |
Osi Pharmaceuticals, Inc. |
Methods for the identification of agents that inhibit mesenchymal-like tumor cells or their formation
|
WO2010099138A2
(en)
|
2009-02-27 |
2010-09-02 |
Osi Pharmaceuticals, Inc. |
Methods for the identification of agents that inhibit mesenchymal-like tumor cells or their formation
|
US20100222381A1
(en)
|
2009-02-27 |
2010-09-02 |
Hariprasad Vankayalapati |
Cyclopentathiophene/cyclohexathiophene DNA methyltransferase inhibitors
|
JP2012519282A
(en)
|
2009-02-27 |
2012-08-23 |
オーエスアイ・ファーマシューティカルズ,エルエルシー |
Methods for identifying mesenchymal tumor cells or agents that inhibit their production
|
US20120064072A1
(en)
|
2009-03-18 |
2012-03-15 |
Maryland Franklin |
Combination Cancer Therapy Comprising Administration of an EGFR Inhibitor and an IGF-1R Inhibitor
|
WO2011027249A2
(en)
|
2009-09-01 |
2011-03-10 |
Pfizer Inc. |
Benzimidazole derivatives
|
US20120316187A1
(en)
|
2009-11-13 |
2012-12-13 |
Pangaea Biotech, S.L. |
Molecular biomarkers for predicting response to tyrosine kinase inhibitors in lung cancer
|
WO2011098971A1
(en)
|
2010-02-12 |
2011-08-18 |
Pfizer Inc. |
Salts and polymorphs of 8-fluoro-2-{4-[(methylamino}methyl]phenyl}-1,3,4,5-tetrahydro-6h-azepino[5,4,3-cd]indol-6-one
|
US20110217309A1
(en)
|
2010-03-03 |
2011-09-08 |
Buck Elizabeth A |
Biological markers predictive of anti-cancer response to insulin-like growth factor-1 receptor kinase inhibitors
|
JP2013527748A
(en)
|
2010-03-03 |
2013-07-04 |
オーエスアイ・ファーマシューティカルズ,エルエルシー |
Biological markers useful for predicting anticancer responses to insulin-like growth factor 1 receptor kinase inhibitors
|
ES2611479T3
(en)
|
2010-06-16 |
2017-05-09 |
University Of Pittsburgh- Of The Commonwealth System Of Higher Education |
Endoplasmin antibodies and their use
|
EP2586443B1
(en)
|
2010-06-25 |
2016-03-16 |
Eisai R&D Management Co., Ltd. |
Antitumor agent using compounds having kinase inhibitory effect in combination
|
EP2630134B9
(en)
|
2010-10-20 |
2018-04-18 |
Pfizer Inc |
Pyridine-2- derivatives as smoothened receptor modulators
|
JP2014504269A
(en)
*
|
2010-11-05 |
2014-02-20 |
グラクソスミスクライン、インテレクチュアル、プロパティー、ナンバー2、リミテッド |
Chemical compound
|
EP2468883A1
(en)
|
2010-12-22 |
2012-06-27 |
Pangaea Biotech S.L. |
Molecular biomarkers for predicting response to tyrosine kinase inhibitors in lung cancer
|
US9134297B2
(en)
|
2011-01-11 |
2015-09-15 |
Icahn School Of Medicine At Mount Sinai |
Method and compositions for treating cancer and related methods
|
US20120214830A1
(en)
|
2011-02-22 |
2012-08-23 |
OSI Pharmaceuticals, LLC |
Biological markers predictive of anti-cancer response to insulin-like growth factor-1 receptor kinase inhibitors in hepatocellular carcinoma
|
EP2492688A1
(en)
|
2011-02-23 |
2012-08-29 |
Pangaea Biotech, S.A. |
Molecular biomarkers for predicting response to antitumor treatment in lung cancer
|
BR112013023050A8
(en)
|
2011-03-09 |
2018-09-25 |
G Pestell Richard |
ccr5 antagonist, method for determining whether a human individual having prostate cancer is suffering from or at risk of metastasis, to identify a ccr5 antagonist, method for determining whether a human individual having prostate cancer is suffering from or under risk of developing metastasis, to identify a candidate compound, to produce in vitro primary epithelial cells, to diagnose prostate cancer, to select a treatment for an individual having a prostate cancer / tumor, cell line, and, animal model
|
WO2012129145A1
(en)
|
2011-03-18 |
2012-09-27 |
OSI Pharmaceuticals, LLC |
Nscle combination therapy
|
US9150644B2
(en)
|
2011-04-12 |
2015-10-06 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Human monoclonal antibodies that bind insulin-like growth factor (IGF) I and II
|
CA2828946C
(en)
|
2011-04-18 |
2016-06-21 |
Eisai R&D Management Co., Ltd. |
Therapeutic agent for tumor
|
EP2699598B1
(en)
|
2011-04-19 |
2019-03-06 |
Pfizer Inc |
Combinations of anti-4-1bb antibodies and adcc-inducing antibodies for the treatment of cancer
|
WO2012149014A1
(en)
|
2011-04-25 |
2012-11-01 |
OSI Pharmaceuticals, LLC |
Use of emt gene signatures in cancer drug discovery, diagnostics, and treatment
|
ES2705950T3
(en)
|
2011-06-03 |
2019-03-27 |
Eisai R&D Man Co Ltd |
Biomarkers to predict and assess the responsiveness of subjects with thyroid and kidney cancer to lenvatinib compounds
|
ES2671748T3
(en)
|
2011-07-21 |
2018-06-08 |
Tolero Pharmaceuticals, Inc. |
Heterocyclic protein kinase inhibitors
|
JP6297490B2
(en)
|
2011-08-31 |
2018-03-20 |
ジェネンテック, インコーポレイテッド |
Diagnostic marker
|
WO2013042006A1
(en)
|
2011-09-22 |
2013-03-28 |
Pfizer Inc. |
Pyrrolopyrimidine and purine derivatives
|
WO2013055530A1
(en)
|
2011-09-30 |
2013-04-18 |
Genentech, Inc. |
Diagnostic methylation markers of epithelial or mesenchymal phenotype and response to egfr kinase inhibitor in tumours or tumour cells
|
EP3275902A1
(en)
|
2011-10-04 |
2018-01-31 |
IGEM Therapeutics Limited |
Ige anti-hmw-maa antibody
|
BR112014011115A2
(en)
|
2011-11-08 |
2017-06-13 |
Pfizer |
Methods for treating inflammatory disorders using anti-csf antibodies
|
WO2013096151A1
(en)
*
|
2011-12-22 |
2013-06-27 |
Glaxosmithkline Llc |
Chemical compounds
|
WO2013096153A1
(en)
*
|
2011-12-22 |
2013-06-27 |
Glaxosmithkline Llc |
Chemical compounds
|
WO2013152252A1
(en)
|
2012-04-06 |
2013-10-10 |
OSI Pharmaceuticals, LLC |
Combination anti-cancer therapy
|
CA2873743C
(en)
|
2012-05-14 |
2022-12-06 |
Prostagene, Llc |
Using modulators of ccr5 for treating cancer
|
WO2013190089A1
(en)
|
2012-06-21 |
2013-12-27 |
Pangaea Biotech, S.L. |
Molecular biomarkers for predicting outcome in lung cancer
|
US9394257B2
(en)
|
2012-10-16 |
2016-07-19 |
Tolero Pharmaceuticals, Inc. |
PKM2 modulators and methods for their use
|
US9260426B2
(en)
|
2012-12-14 |
2016-02-16 |
Arrien Pharmaceuticals Llc |
Substituted 1H-pyrrolo [2, 3-b] pyridine and 1H-pyrazolo [3, 4-b] pyridine derivatives as salt inducible kinase 2 (SIK2) inhibitors
|
CN104755463A
(en)
|
2012-12-21 |
2015-07-01 |
卫材R&D管理有限公司 |
Amorphous form of quinoline derivative, and method for producing same
|
WO2014134202A1
(en)
|
2013-02-26 |
2014-09-04 |
Triact Therapeutics, Inc. |
Cancer therapy
|
US10202356B2
(en)
|
2013-03-14 |
2019-02-12 |
Tolero Pharmaceuticals, Inc. |
JAK2 and ALK2 inhibitors and methods for their use
|
EP2976085A1
(en)
|
2013-03-21 |
2016-01-27 |
INSERM - Institut National de la Santé et de la Recherche Médicale |
Method and pharmaceutical composition for use in the treatment of chronic liver diseases associated with a low hepcidin expression
|
US9206188B2
(en)
|
2013-04-18 |
2015-12-08 |
Arrien Pharmaceuticals Llc |
Substituted pyrrolo[2,3-b]pyridines as ITK and JAK inhibitors
|
MX368099B
(en)
|
2013-05-14 |
2019-09-19 |
Eisai R&D Man Co Ltd |
Biomarkers for predicting and assessing responsiveness of endometrial cancer subjects to lenvatinib compounds.
|
US9381246B2
(en)
|
2013-09-09 |
2016-07-05 |
Triact Therapeutics, Inc. |
Cancer therapy
|
DK3052102T3
(en)
|
2013-10-04 |
2020-03-09 |
Aptose Biosciences Inc |
CANCER TREATMENT COMPOSITIONS
|
UA115388C2
(en)
|
2013-11-21 |
2017-10-25 |
Пфайзер Інк. |
2,6-substituted purine derivatives and their use in the treatment of proliferative disorders
|
WO2015156674A2
(en)
|
2014-04-10 |
2015-10-15 |
Stichting Het Nederlands Kanker Instituut |
Method for treating cancer
|
WO2015155624A1
(en)
|
2014-04-10 |
2015-10-15 |
Pfizer Inc. |
Dihydropyrrolopyrimidine derivatives
|
PT3137460T
(en)
|
2014-04-30 |
2019-12-30 |
Pfizer |
Cycloalkyl-linked diheterocycle derivatives
|
WO2016001789A1
(en)
|
2014-06-30 |
2016-01-07 |
Pfizer Inc. |
Pyrimidine derivatives as pi3k inhibitors for use in the treatment of cancer
|
ES2848857T3
(en)
|
2014-07-31 |
2021-08-12 |
Us Gov Health & Human Services |
Human monoclonal antibodies against EphA4 and their use
|
JO3783B1
(en)
|
2014-08-28 |
2021-01-31 |
Eisai R&D Man Co Ltd |
Highly pure quinoline derivative and method for producing the same
|
ES2746839T3
(en)
|
2014-12-18 |
2020-03-09 |
Pfizer |
Pyrimidine and triazine derivatives and their use as AXL inhibitors
|
MX2017008421A
(en)
|
2014-12-24 |
2018-03-23 |
Genentech Inc |
Therapeutic, diagnostic and prognostic methods for cancer of the bladder.
|
DK3263106T3
(en)
|
2015-02-25 |
2024-01-08 |
Eisai R&D Man Co Ltd |
PROCESS FOR SUPPRESSING BITTERNESS OF QUINOLINE DERIVATIVES
|
CA2978226A1
(en)
|
2015-03-04 |
2016-09-09 |
Merck Sharpe & Dohme Corp. |
Combination of a pd-1 antagonist and a vegfr/fgfr/ret tyrosine kinase inhibitor for treating cancer
|
MX2017013383A
(en)
|
2015-04-20 |
2017-12-07 |
Tolero Pharmaceuticals Inc |
Predicting response to alvocidib by mitochondrial profiling.
|
US10011629B2
(en)
|
2015-05-01 |
2018-07-03 |
Cocrystal Pharma, Inc. |
Nucleoside analogs for treatment of the flaviviridae family of viruses and cancer
|
KR102608921B1
(en)
|
2015-05-18 |
2023-12-01 |
스미토모 파마 온콜로지, 인크. |
Albocidip prodrug with increased bioavailability
|
CN107801379B
(en)
|
2015-06-16 |
2021-05-25 |
卫材R&D管理有限公司 |
Anticancer agent
|
WO2017009751A1
(en)
|
2015-07-15 |
2017-01-19 |
Pfizer Inc. |
Pyrimidine derivatives
|
MX2018001289A
(en)
|
2015-08-03 |
2018-04-30 |
Tolero Pharmaceuticals Inc |
Combination therapies for treatment of cancer.
|
JP6877429B2
(en)
|
2015-12-03 |
2021-05-26 |
アジオス ファーマシューティカルズ, インコーポレイテッド |
MAT2A inhibitor for treating MTAP null cancer
|
US11279694B2
(en)
|
2016-11-18 |
2022-03-22 |
Sumitomo Dainippon Pharma Oncology, Inc. |
Alvocidib prodrugs and their use as protein kinase inhibitors
|
US10132797B2
(en)
|
2016-12-19 |
2018-11-20 |
Tolero Pharmaceuticals, Inc. |
Profiling peptides and methods for sensitivity profiling
|
RS62456B1
(en)
|
2016-12-22 |
2021-11-30 |
Amgen Inc |
Benzisothiazole, isothiazolo[3,4-b]pyridine, quinazoline, phthalazine, pyrido[2,3-d]pyridazine and pyrido[2,3-d]pyrimidine derivatives as kras g12c inhibitors for treating lung, pancreatic or colorectal cancer
|
JOP20190272A1
(en)
|
2017-05-22 |
2019-11-21 |
Amgen Inc |
Kras g12c inhibitors and methods of using the same
|
SG11202001499WA
(en)
|
2017-09-08 |
2020-03-30 |
Amgen Inc |
Inhibitors of kras g12c and methods of using the same
|
WO2019055579A1
(en)
|
2017-09-12 |
2019-03-21 |
Tolero Pharmaceuticals, Inc. |
Treatment regimen for cancers that are insensitive to bcl-2 inhibitors using the mcl-1 inhibitor alvocidib
|
US20200237766A1
(en)
|
2017-10-13 |
2020-07-30 |
Tolero Pharmaceuticals, Inc. |
Pkm2 activators in combination with reactive oxygen species for treatment of cancer
|
US11045484B2
(en)
|
2018-05-04 |
2021-06-29 |
Amgen Inc. |
KRAS G12C inhibitors and methods of using the same
|
EP3788038B1
(en)
|
2018-05-04 |
2023-10-11 |
Amgen Inc. |
Kras g12c inhibitors and methods of using the same
|
WO2019217691A1
(en)
|
2018-05-10 |
2019-11-14 |
Amgen Inc. |
Kras g12c inhibitors for the treatment of cancer
|
US11096939B2
(en)
|
2018-06-01 |
2021-08-24 |
Amgen Inc. |
KRAS G12C inhibitors and methods of using the same
|
EP3802537A1
(en)
|
2018-06-11 |
2021-04-14 |
Amgen Inc. |
Kras g12c inhibitors for treating cancer
|
MX2020012261A
(en)
|
2018-06-12 |
2021-03-31 |
Amgen Inc |
Kras g12c inhibitors encompassing a piperazine ring and use thereof in the treatment of cancer.
|
CA3103995A1
(en)
|
2018-07-26 |
2020-01-30 |
Sumitomo Dainippon Pharma Oncology, Inc. |
Methods for treating diseases associated with abnormal acvr1 expression and acvr1 inhibitors for use in the same
|
US20210393632A1
(en)
|
2018-10-04 |
2021-12-23 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Egfr inhibitors for treating keratodermas
|
JP2020090482A
(en)
|
2018-11-16 |
2020-06-11 |
アムジエン・インコーポレーテツド |
Improved synthesis of key intermediate of kras g12c inhibitor compound
|
CA3117222A1
(en)
|
2018-11-19 |
2020-05-28 |
Amgen Inc. |
Kras g12c inhibitors and methods of using the same
|
JP7377679B2
(en)
|
2018-11-19 |
2023-11-10 |
アムジエン・インコーポレーテツド |
Combination therapy comprising a KRASG12C inhibitor and one or more additional pharmaceutically active agents for the treatment of cancer
|
MX2021006544A
(en)
|
2018-12-04 |
2021-07-07 |
Sumitomo Pharma Oncology Inc |
Cdk9 inhibitors and polymorphs thereof for use as agents for treatment of cancer.
|
PE20211475A1
(en)
|
2018-12-20 |
2021-08-05 |
Amgen Inc |
KIF18A INHIBITORS
|
MA54546A
(en)
|
2018-12-20 |
2022-03-30 |
Amgen Inc |
HETEROARYL AMIDES USEFUL AS KIF18A INHIBITORS
|
MA54547A
(en)
|
2018-12-20 |
2022-03-30 |
Amgen Inc |
HETEROARYL AMIDES USEFUL AS KIF18A INHIBITORS
|
ES2953821T3
(en)
|
2018-12-20 |
2023-11-16 |
Amgen Inc |
KIF18A inhibitors
|
EP3924351A4
(en)
|
2019-02-12 |
2022-12-21 |
Sumitomo Pharma Oncology, Inc. |
Formulations comprising heterocyclic protein kinase inhibitors
|
JP2022522777A
(en)
|
2019-03-01 |
2022-04-20 |
レボリューション メディシンズ インコーポレイテッド |
Bicyclic heteroaryl compounds and their use
|
US20230096028A1
(en)
|
2019-03-01 |
2023-03-30 |
Revolution Medicines, Inc. |
Bicyclic heterocyclyl compounds and uses thereof
|
WO2020191326A1
(en)
|
2019-03-20 |
2020-09-24 |
Sumitomo Dainippon Pharma Oncology, Inc. |
Treatment of acute myeloid leukemia (aml) with venetoclax failure
|
AU2020245437A1
(en)
|
2019-03-22 |
2021-09-30 |
Sumitomo Pharma Oncology, Inc. |
Compositions comprising PKM2 modulators and methods of treatment using the same
|
EP3738593A1
(en)
|
2019-05-14 |
2020-11-18 |
Amgen, Inc |
Dosing of kras inhibitor for treatment of cancers
|
EP3972973A1
(en)
|
2019-05-21 |
2022-03-30 |
Amgen Inc. |
Solid state forms
|
CN114401953A
(en)
|
2019-08-02 |
2022-04-26 |
美国安进公司 |
KIF18A inhibitors
|
US20220372018A1
(en)
|
2019-08-02 |
2022-11-24 |
Amgen Inc. |
Kif18a inhibitors
|
WO2021026098A1
(en)
|
2019-08-02 |
2021-02-11 |
Amgen Inc. |
Kif18a inhibitors
|
AU2020324963A1
(en)
|
2019-08-02 |
2022-02-24 |
Amgen Inc. |
KIF18A inhibitors
|
WO2021081212A1
(en)
|
2019-10-24 |
2021-04-29 |
Amgen Inc. |
Pyridopyrimidine derivatives useful as kras g12c and kras g12d inhibitors in the treatment of cancer
|
TW202132314A
(en)
|
2019-11-04 |
2021-09-01 |
美商銳新醫藥公司 |
Ras inhibitors
|
CA3159559A1
(en)
|
2019-11-04 |
2021-05-14 |
Revolution Medicines, Inc. |
Ras inhibitors
|
EP4054719A1
(en)
|
2019-11-04 |
2022-09-14 |
Revolution Medicines, Inc. |
Ras inhibitors
|
PE20230249A1
(en)
|
2019-11-08 |
2023-02-07 |
Revolution Medicines Inc |
BICYCLIC HETEROARYL COMPOUNDS AND THEIR USES
|
AR120456A1
(en)
|
2019-11-14 |
2022-02-16 |
Amgen Inc |
ENHANCED SYNTHESIS OF KRAS G12C INHIBITOR COMPOUND
|
WO2021097212A1
(en)
|
2019-11-14 |
2021-05-20 |
Amgen Inc. |
Improved synthesis of kras g12c inhibitor compound
|
JP2023505100A
(en)
|
2019-11-27 |
2023-02-08 |
レボリューション メディシンズ インコーポレイテッド |
Covalent RAS inhibitors and uses thereof
|
BR112022010086A2
(en)
|
2020-01-07 |
2022-09-06 |
Revolution Medicines Inc |
SHP2 INHIBITOR DOSAGE AND CANCER TREATMENT METHODS
|
WO2021155006A1
(en)
|
2020-01-31 |
2021-08-05 |
Les Laboratoires Servier Sas |
Inhibitors of cyclin-dependent kinases and uses thereof
|
CN115916194A
(en)
|
2020-06-18 |
2023-04-04 |
锐新医药公司 |
Methods for delaying, preventing and treating acquired resistance to RAS inhibitors
|
AU2021344830A1
(en)
|
2020-09-03 |
2023-04-06 |
Revolution Medicines, Inc. |
Use of SOS1 inhibitors to treat malignancies with SHP2 mutations
|
KR20230067635A
(en)
|
2020-09-15 |
2023-05-16 |
레볼루션 메디슨즈, 인크. |
Indole derivatives as RAS inhibitors in the treatment of cancer
|
WO2023077259A1
(en)
*
|
2021-11-02 |
2023-05-11 |
Enliven Therapeutics, Inc. |
Fused tetracyclic quinazoline derivatives as inhibitors of erbb2
|
CN117396472A
(en)
|
2020-12-22 |
2024-01-12 |
上海齐鲁锐格医药研发有限公司 |
SOS1 inhibitors and uses thereof
|
WO2022235870A1
(en)
|
2021-05-05 |
2022-11-10 |
Revolution Medicines, Inc. |
Ras inhibitors for the treatment of cancer
|
CN117500811A
(en)
|
2021-05-05 |
2024-02-02 |
锐新医药公司 |
Covalent RAS inhibitors and uses thereof
|
CR20230570A
(en)
|
2021-05-05 |
2024-01-22 |
Revolution Medicines Inc |
Ras inhibitors
|
AR127308A1
(en)
|
2021-10-08 |
2024-01-10 |
Revolution Medicines Inc |
RAS INHIBITORS
|
WO2023081637A1
(en)
|
2021-11-02 |
2023-05-11 |
Enliven Therapeutics, Inc. |
Fused tetracyclic quinazoline derivatives as inhibitors of erbb2
|
TW202340214A
(en)
|
2021-12-17 |
2023-10-16 |
美商健臻公司 |
Pyrazolopyrazine compounds as shp2 inhibitors
|
EP4227307A1
(en)
|
2022-02-11 |
2023-08-16 |
Genzyme Corporation |
Pyrazolopyrazine compounds as shp2 inhibitors
|
WO2023172940A1
(en)
|
2022-03-08 |
2023-09-14 |
Revolution Medicines, Inc. |
Methods for treating immune refractory lung cancer
|
WO2023240263A1
(en)
|
2022-06-10 |
2023-12-14 |
Revolution Medicines, Inc. |
Macrocyclic ras inhibitors
|
WO2024081916A1
(en)
|
2022-10-14 |
2024-04-18 |
Black Diamond Therapeutics, Inc. |
Methods of treating cancers using isoquinoline or 6-aza-quinoline derivatives
|