AU1925197A - 4-amino-pyrimidine derivates, medicaments containing these compounds, their use and process for their production - Google Patents

4-amino-pyrimidine derivates, medicaments containing these compounds, their use and process for their production

Info

Publication number
AU1925197A
AU1925197A AU19251/97A AU1925197A AU1925197A AU 1925197 A AU1925197 A AU 1925197A AU 19251/97 A AU19251/97 A AU 19251/97A AU 1925197 A AU1925197 A AU 1925197A AU 1925197 A AU1925197 A AU 1925197A
Authority
AU
Australia
Prior art keywords
amino
compounds
production
medicaments containing
pyrimidine derivates
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
AU19251/97A
Other versions
AU710274B2 (en
Inventor
Georg Dahmann
Frank Himmelsbach
Thomas Metz
Thomas Von Ruden
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim Pharma GmbH and Co KG
Original Assignee
Dr Karl Thomae GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE1996108631 external-priority patent/DE19608631A1/en
Application filed by Dr Karl Thomae GmbH filed Critical Dr Karl Thomae GmbH
Publication of AU1925197A publication Critical patent/AU1925197A/en
Application granted granted Critical
Publication of AU710274B2 publication Critical patent/AU710274B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
AU19251/97A 1996-03-06 1997-03-03 4-amino-pyrimidine derivates, medicaments containing these compounds, their use and process for their production Ceased AU710274B2 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
DE1996108631 DE19608631A1 (en) 1996-03-06 1996-03-06 New (heterocyclyl- pyrimidino or -pyrido)fused pyrimidine derivatives
DE19608631 1996-03-06
DE19629652 1996-07-23
DE19629652A DE19629652A1 (en) 1996-03-06 1996-07-23 4-Amino-pyrimidine derivatives, medicaments containing these compounds, their use and processes for their preparation
PCT/EP1997/001057 WO1997032881A1 (en) 1996-03-06 1997-03-03 4-amino pyrimidine derivates, medicaments containing these compounds, their use and process for their production

Publications (2)

Publication Number Publication Date
AU1925197A true AU1925197A (en) 1997-09-22
AU710274B2 AU710274B2 (en) 1999-09-16

Family

ID=26023531

Family Applications (1)

Application Number Title Priority Date Filing Date
AU19251/97A Ceased AU710274B2 (en) 1996-03-06 1997-03-03 4-amino-pyrimidine derivates, medicaments containing these compounds, their use and process for their production

Country Status (19)

Country Link
EP (1) EP0885226A1 (en)
JP (1) JP2000506847A (en)
KR (1) KR19990087550A (en)
CN (1) CN1212695A (en)
AU (1) AU710274B2 (en)
BG (1) BG102708A (en)
BR (1) BR9708312A (en)
CA (1) CA2243994A1 (en)
CZ (1) CZ281798A3 (en)
DE (1) DE19629652A1 (en)
EE (1) EE9800277A (en)
HU (1) HUP9901820A3 (en)
IL (1) IL125404A0 (en)
NO (1) NO984084D0 (en)
NZ (1) NZ331546A (en)
PL (1) PL328771A1 (en)
SK (1) SK120598A3 (en)
TR (1) TR199801749T2 (en)
WO (1) WO1997032881A1 (en)

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JOP20190272A1 (en) 2017-05-22 2019-11-21 Amgen Inc Kras g12c inhibitors and methods of using the same
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EP3788038B1 (en) 2018-05-04 2023-10-11 Amgen Inc. Kras g12c inhibitors and methods of using the same
US11045484B2 (en) 2018-05-04 2021-06-29 Amgen Inc. KRAS G12C inhibitors and methods of using the same
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US20210393632A1 (en) 2018-10-04 2021-12-23 INSERM (Institut National de la Santé et de la Recherche Médicale) Egfr inhibitors for treating keratodermas
JP2020090482A (en) 2018-11-16 2020-06-11 アムジエン・インコーポレーテツド Improved synthesis of key intermediate of kras g12c inhibitor compound
JP7377679B2 (en) 2018-11-19 2023-11-10 アムジエン・インコーポレーテツド Combination therapy comprising a KRASG12C inhibitor and one or more additional pharmaceutically active agents for the treatment of cancer
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DE4431867A1 (en) * 1994-09-07 1996-03-14 Thomae Gmbh Dr K New 4-amino-pyrimido-pyrimidine derivs.

Also Published As

Publication number Publication date
DE19629652A1 (en) 1998-01-29
PL328771A1 (en) 1999-02-15
IL125404A0 (en) 1999-03-12
CN1212695A (en) 1999-03-31
NZ331546A (en) 2000-03-27
EP0885226A1 (en) 1998-12-23
AU710274B2 (en) 1999-09-16
NO984084L (en) 1998-09-04
BG102708A (en) 1999-09-30
SK120598A3 (en) 1999-06-11
KR19990087550A (en) 1999-12-27
HUP9901820A3 (en) 2001-10-29
NO984084D0 (en) 1998-09-04
EE9800277A (en) 1999-02-15
BR9708312A (en) 1999-08-03
CA2243994A1 (en) 1997-09-12
TR199801749T2 (en) 1998-12-21
WO1997032881A1 (en) 1997-09-12
JP2000506847A (en) 2000-06-06
HUP9901820A2 (en) 1999-09-28
CZ281798A3 (en) 1999-02-17

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Legal Events

Date Code Title Description
MK14 Patent ceased section 143(a) (annual fees not paid) or expired