ATE73775T1 - 2-dithioalkyl-dihydropyridine, verfahren zu ihrer herstellung und pharmazeutische zusammenstellungen, die sie enthalten. - Google Patents

2-dithioalkyl-dihydropyridine, verfahren zu ihrer herstellung und pharmazeutische zusammenstellungen, die sie enthalten.

Info

Publication number
ATE73775T1
ATE73775T1 AT87119081T AT87119081T ATE73775T1 AT E73775 T1 ATE73775 T1 AT E73775T1 AT 87119081 T AT87119081 T AT 87119081T AT 87119081 T AT87119081 T AT 87119081T AT E73775 T1 ATE73775 T1 AT E73775T1
Authority
AT
Austria
Prior art keywords
groups
dithioalkyl
dihydropyridines
processes
preparation
Prior art date
Application number
AT87119081T
Other languages
English (en)
Inventor
Marco Frigerio
Carmelo A Gandolfi
Sergio Tognella
Original Assignee
Boehringer Mannheim Italia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Mannheim Italia filed Critical Boehringer Mannheim Italia
Application granted granted Critical
Publication of ATE73775T1 publication Critical patent/ATE73775T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pyridine Compounds (AREA)
AT87119081T 1986-12-24 1987-12-22 2-dithioalkyl-dihydropyridine, verfahren zu ihrer herstellung und pharmazeutische zusammenstellungen, die sie enthalten. ATE73775T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT8622881A IT1213440B (it) 1986-12-24 1986-12-24 2-ditioalchil-diidropiridine, un metodo per la loro preparazione e composizioni farmaceutiche chele contengono.
EP87119081A EP0272694B1 (de) 1986-12-24 1987-12-22 2-Dithioalkyl-dihydropyridine, Verfahren zu ihrer Herstellung und pharmazeutische Zusammenstellungen, die sie enthalten

Publications (1)

Publication Number Publication Date
ATE73775T1 true ATE73775T1 (de) 1992-04-15

Family

ID=11201500

Family Applications (1)

Application Number Title Priority Date Filing Date
AT87119081T ATE73775T1 (de) 1986-12-24 1987-12-22 2-dithioalkyl-dihydropyridine, verfahren zu ihrer herstellung und pharmazeutische zusammenstellungen, die sie enthalten.

Country Status (7)

Country Link
US (1) US4956369A (de)
EP (1) EP0272694B1 (de)
JP (1) JPS63170361A (de)
AT (1) ATE73775T1 (de)
CA (1) CA1313526C (de)
DE (1) DE3777575D1 (de)
IT (1) IT1213440B (de)

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4284634A (en) * 1975-07-02 1981-08-18 Fujisawa Pharmaceutical Co., Ltd. 1,4-Dihydropyridine derivatives, and pharmaceutical method of the same
NZ201395A (en) * 1981-07-30 1987-02-20 Bayer Ag Pharmaceutical compositions containing 1,4-dihydropyridines and certain of these dihydropyridines
DE3207982A1 (de) * 1982-03-05 1983-09-08 Bayer Ag, 5090 Leverkusen Neue 1,4-dihydropyridine, verfahren zu ihrer herstellung und ihrer verwendung in arzneimitteln
IL68604A0 (en) * 1982-05-21 1983-09-30 Haessle Ab Processes for preparing therapeutically active dihydropyridines and intermediates for the processes
US4690935A (en) * 1983-03-31 1987-09-01 Wayne State University Inhibition of tumor growth and metastasis with calcium channel blocker compounds
EP0169009A3 (de) * 1984-07-17 1988-08-31 FISONS plc Dihydropyridinderivate und ihre Herstellung, Formulierung und Verwendung als Pharmazeutika
EP0200524A3 (de) * 1985-05-03 1987-06-16 Pfizer Limited Dihydropyridin-Calcium-Antagonisten

Also Published As

Publication number Publication date
DE3777575D1 (de) 1992-04-23
CA1313526C (en) 1993-02-09
EP0272694B1 (de) 1992-03-18
IT1213440B (it) 1989-12-20
JPS63170361A (ja) 1988-07-14
EP0272694A1 (de) 1988-06-29
IT8622881A0 (it) 1986-12-24
US4956369A (en) 1990-09-11

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