ATE69507T1 - Verfahren und geraete zur trennung, vermischung und bestimmung von komponenten in spezifischen bindungstests. - Google Patents
Verfahren und geraete zur trennung, vermischung und bestimmung von komponenten in spezifischen bindungstests.Info
- Publication number
- ATE69507T1 ATE69507T1 AT86905538T AT86905538T ATE69507T1 AT E69507 T1 ATE69507 T1 AT E69507T1 AT 86905538 T AT86905538 T AT 86905538T AT 86905538 T AT86905538 T AT 86905538T AT E69507 T1 ATE69507 T1 AT E69507T1
- Authority
- AT
- Austria
- Prior art keywords
- separation
- methods
- specific binding
- binding assays
- determination
- Prior art date
Links
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5021—Test tubes specially adapted for centrifugation purposes
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
- G01N33/537—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with separation of immune complex from unbound antigen or antibody
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
- G01N33/537—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with separation of immune complex from unbound antigen or antibody
- G01N33/5375—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with separation of immune complex from unbound antigen or antibody by changing the physical or chemical properties of the medium or immunochemicals, e.g. temperature, density, pH, partitioning
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/806—Electrical property or magnetic property
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/824—Immunological separation techniques
Landscapes
- Health & Medical Sciences (AREA)
- Immunology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- General Health & Medical Sciences (AREA)
- Analytical Chemistry (AREA)
- Food Science & Technology (AREA)
- General Physics & Mathematics (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Cell Biology (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Pathology (AREA)
- Clinical Laboratory Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Accessories For Mixers (AREA)
- Sampling And Sample Adjustment (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US76810885A | 1985-08-21 | 1985-08-21 | |
EP86905538A EP0233939B1 (de) | 1985-08-21 | 1986-08-21 | Verfahren und geräte zur trennung, vermischung und bestimmung von komponenten in spezifischen bindungstests |
PCT/US1986/001720 WO1987001206A1 (en) | 1985-08-21 | 1986-08-21 | Methods and devices for separating, mixing, and detecting components in specific binding assays |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE69507T1 true ATE69507T1 (de) | 1991-11-15 |
Family
ID=25081541
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT86905538T ATE69507T1 (de) | 1985-08-21 | 1986-08-21 | Verfahren und geraete zur trennung, vermischung und bestimmung von komponenten in spezifischen bindungstests. |
Country Status (8)
Country | Link |
---|---|
US (1) | US4868130A (de) |
EP (1) | EP0233939B1 (de) |
JP (1) | JP2591738B2 (de) |
KR (1) | KR880700269A (de) |
AT (1) | ATE69507T1 (de) |
CA (1) | CA1292092C (de) |
DE (1) | DE3682502D1 (de) |
WO (1) | WO1987001206A1 (de) |
Families Citing this family (54)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5073341A (en) * | 1985-08-21 | 1991-12-17 | Biotope, Inc. | Devices for conducting specific binding assays |
US5470711A (en) * | 1986-03-26 | 1995-11-28 | Synbiotics Corporation | Saliva enhancement reagent for feline leukemia virus elisa |
SE8703733L (sv) * | 1987-09-28 | 1989-03-29 | Ragnar Soedergaard | Analysmetod foer bestaemning av procent fri substans i biologiska vaetskor genom jaemviktsfoerdelning i olja/vatten system |
ATE91023T1 (de) * | 1987-12-01 | 1993-07-15 | Biotope Inc | Verfahren und vorrichtungen zur durchfuehrung von untersuchungen. |
US5145784A (en) * | 1988-05-04 | 1992-09-08 | Cambridge Biotech Corporation | Double capture assay method employing a capillary flow device |
US5484735A (en) * | 1989-08-23 | 1996-01-16 | Northwestern University | Immunoassay of glycosylated proteins employing antibody directed to reductively glycosylated N-terminal amino acids |
US5279936A (en) * | 1989-12-22 | 1994-01-18 | Syntex (U.S.A.) Inc. | Method of separation employing magnetic particles and second medium |
DE4041300A1 (de) * | 1989-12-22 | 1991-06-27 | Syntex Inc | Verfahren zur trennung von komponenten in einer mischung |
US5223393A (en) * | 1990-06-12 | 1993-06-29 | Microgenics Corporation | Detection of analytes having binding sites for at least two binding moieties |
US6703236B2 (en) * | 1990-11-29 | 2004-03-09 | Applera Corporation | Thermal cycler for automatic performance of the polymerase chain reaction with close temperature control |
KR100236506B1 (ko) * | 1990-11-29 | 2000-01-15 | 퍼킨-엘머시터스인스트루먼츠 | 폴리머라제 연쇄 반응 수행 장치 |
US5506114A (en) * | 1992-02-07 | 1996-04-09 | Osborn Laboratories | Methods and kits for detecting the presence or concentration of biological analytes |
US5629168A (en) * | 1992-02-10 | 1997-05-13 | British Technology Group Limited | Chemiluminescent enhancers |
GB2312746B (en) * | 1996-04-24 | 2000-07-19 | Molecular Light Technology Lim | Detection of an analyte in a Water Immiscible Solvent |
US5795784A (en) | 1996-09-19 | 1998-08-18 | Abbott Laboratories | Method of performing a process for determining an item of interest in a sample |
US5856194A (en) | 1996-09-19 | 1999-01-05 | Abbott Laboratories | Method for determination of item of interest in a sample |
US6143496A (en) | 1997-04-17 | 2000-11-07 | Cytonix Corporation | Method of sampling, amplifying and quantifying segment of nucleic acid, polymerase chain reaction assembly having nanoliter-sized sample chambers, and method of filling assembly |
US6752965B2 (en) * | 1998-03-06 | 2004-06-22 | Abner Levy | Self resealing elastomeric closure |
US6030582A (en) * | 1998-03-06 | 2000-02-29 | Levy; Abner | Self-resealing, puncturable container cap |
US7060431B2 (en) | 1998-06-24 | 2006-06-13 | Illumina, Inc. | Method of making and decoding of array sensors with microspheres |
CA2283597C (en) | 1998-10-02 | 2008-02-05 | Ortho-Clinical Diagnostics, Inc. | Reduced cortisol conjugates |
ATE427159T1 (de) † | 1999-05-14 | 2009-04-15 | Gen Probe Inc | Fluid-transfer-gerat zur verwendung mit durchdringbarer kappe |
US6623982B1 (en) * | 1999-07-12 | 2003-09-23 | Immunivest Corporation | Increased separation efficiency via controlled aggregation of magnetic nanoparticles |
CA2441206A1 (en) | 2001-03-19 | 2002-09-26 | Gyros Ab | Characterization of reaction variables |
CA2513985C (en) | 2003-01-21 | 2012-05-29 | Illumina Inc. | Chemical reaction monitor |
US20050181513A1 (en) * | 2004-02-18 | 2005-08-18 | Viorica Lopez-Avila | Methods and compositions for assessing a sample by MAILDI mass spectrometry |
US7776531B1 (en) | 2004-03-25 | 2010-08-17 | Illumina, Inc. | Compositions and methods for stabilizing surface bound probes |
WO2005113147A2 (en) * | 2004-04-08 | 2005-12-01 | Biomatrica, Inc. | Integration of sample storage and sample management for life science |
US9488665B2 (en) * | 2005-09-13 | 2016-11-08 | Chrome Red Technologies, Llc | Magnetic particle tagged reagents and techniques |
US20070113908A1 (en) * | 2005-11-18 | 2007-05-24 | The Ohio State University And Bioloc, Inc. | Valve for microfluidic chips |
EP2559666B1 (de) | 2007-08-27 | 2014-07-23 | Technion Research & Development Foundation Ltd. | Durch Elektrolyse gesteuerte pH-Gradienten und ihre Verwendung bei der isoelektrischen Fokussierung |
MX2011004169A (es) * | 2008-10-31 | 2011-09-27 | Bio Merieux Inc | Metodos para la separacion y caracterizacion de microorganismos utilizando agentes identificadores. |
AU2010245860B2 (en) * | 2009-05-07 | 2015-07-16 | Biomerieux, Inc. | Methods for antimicrobial resistance determination |
WO2010132453A2 (en) * | 2009-05-11 | 2010-11-18 | Nexus Dx, Inc. | Methods and compositions for analyte detection |
US9028664B2 (en) | 2009-08-18 | 2015-05-12 | Technion Research & Development Foundation Limited | Proton concentration topographies, methods and devices for producing the same |
EP2467710B1 (de) | 2009-08-18 | 2020-04-22 | Technion Research & Development Foundation Ltd. | Verfahren und vorrichtungen zur trennung von molekularen analyten |
KR20120107497A (ko) | 2009-12-17 | 2012-10-02 | 아박시스, 인크. | 샘플 내 분석물을 검출하기 위한 신규 분석 및 그것과 관련된 키트 및 조성물 |
US9845489B2 (en) | 2010-07-26 | 2017-12-19 | Biomatrica, Inc. | Compositions for stabilizing DNA, RNA and proteins in saliva and other biological samples during shipping and storage at ambient temperatures |
WO2012018638A2 (en) | 2010-07-26 | 2012-02-09 | Biomatrica, Inc. | Compositions for stabilizing dna, rna and proteins in blood and other biological samples during shipping and storage at ambient temperatures |
US20130071946A1 (en) | 2011-09-21 | 2013-03-21 | Roche Molecular Systems, Inc. | Suspension Container For Binding Particles For The Isolation Of Biological Material |
US20130164860A1 (en) * | 2011-11-04 | 2013-06-27 | Technion Research & Development Foundation Ltd. | Affinity methods and compositions employing electronic control of ph |
US9766207B2 (en) | 2011-11-04 | 2017-09-19 | Bio-Rad Laboratories, Inc. | Affinity methods and compositions employing electronic control of pH |
EP2773221B1 (de) | 2011-11-04 | 2019-01-09 | Bio-Rad Laboratories, Inc. | Gleichzeitige reinigung von zellkomponenten |
EP2814597A4 (de) | 2012-02-15 | 2015-10-28 | Bio Rad Laboratories | Elektronische steuerung von ph-wert und ionenstärke |
US9321012B2 (en) | 2012-04-04 | 2016-04-26 | Bio-Rad Laboratories, Inc. | Electronic protein fractionation |
WO2013158340A1 (en) * | 2012-04-18 | 2013-10-24 | Rarecyte, Inc. | Systems and methods for separation and analysis of target analytes |
WO2014100755A2 (en) | 2012-12-20 | 2014-06-26 | Biomatrica, Inc. | Formulations and methods for stabilizing pcr reagents |
US10364453B1 (en) * | 2013-02-04 | 2019-07-30 | The United States Of America, As Represented By The Secretary Of The Navy | Detecting of bacteria using fluorescently-labeled phage immobilized on an optically transparent surface |
JP6431522B2 (ja) | 2013-03-15 | 2018-11-28 | アボツト・モレキユラー・インコーポレイテツド | 核酸の精製のための1工程法 |
EP3656215B1 (de) | 2014-06-10 | 2021-08-04 | Biomatrica, INC. | Stabilisierung von thrombozyten bei umgebungstemperatur |
KR20230145258A (ko) | 2015-12-08 | 2023-10-17 | 바이오매트리카 인코포레이티드 | 적혈구 침강 속도의 감소 |
DK3400754T3 (da) * | 2016-01-08 | 2021-11-01 | Siemens Healthcare Diagnostics Inc | Varmeelement til sensorarray |
IT201600079328A1 (it) * | 2016-07-28 | 2018-01-28 | Altergon Sa | Metodo migliorato per la decontaminazione di materiale biologico mediante partizione e inattivazione |
JP7408299B2 (ja) * | 2018-06-07 | 2024-01-05 | キヤノン株式会社 | 過酸化水素の検出のための高分子色素および過酸化水素検出用構造体 |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1411382A (en) * | 1971-12-16 | 1975-10-22 | Radiochemical Centre Ltd | Methods of analysis |
US3852194A (en) * | 1972-12-11 | 1974-12-03 | Corning Glass Works | Apparatus and method for fluid collection and partitioning |
GB1566098A (en) * | 1975-11-14 | 1980-04-30 | Nat Res Dev | Separation of solid and liquid components of mixtures |
GB1533272A (en) * | 1976-02-13 | 1978-11-22 | Radiochemical Centre Ltd | Centrifuge tube |
IL56839A0 (en) * | 1979-03-11 | 1979-05-31 | Technion Res & Dev Foundation | Improvement in specific binding assay technique |
IL58943A (en) * | 1979-12-12 | 1983-05-15 | Cais Michael | Method and device for mass transfer operations in immunoassays and other applications |
JPS58205854A (ja) * | 1982-05-25 | 1983-11-30 | Mihama Hisaharu | 潜血反応検査用の固定化抗体 |
DE3222962C2 (de) * | 1982-06-19 | 1987-02-19 | Bayer Ag, 5090 Leverkusen | Siliconpasten für die Trennung von Blutproben |
AU1912783A (en) * | 1982-09-15 | 1984-03-22 | Ortho Diagnostic Systems Inc. | Carousel microparticle separating, washing + reading device |
FI844027A (fi) * | 1984-10-12 | 1986-04-13 | Labsystems Oy | Immunologiskt bestaemningsfoerfarande. |
-
1986
- 1986-08-21 AT AT86905538T patent/ATE69507T1/de not_active IP Right Cessation
- 1986-08-21 CA CA000516560A patent/CA1292092C/en not_active Expired - Fee Related
- 1986-08-21 JP JP61504751A patent/JP2591738B2/ja not_active Expired - Fee Related
- 1986-08-21 DE DE8686905538T patent/DE3682502D1/de not_active Expired - Fee Related
- 1986-08-21 EP EP86905538A patent/EP0233939B1/de not_active Expired - Lifetime
- 1986-08-21 WO PCT/US1986/001720 patent/WO1987001206A1/en active IP Right Grant
-
1987
- 1987-02-20 US US07/017,318 patent/US4868130A/en not_active Expired - Lifetime
- 1987-04-21 KR KR870700345A patent/KR880700269A/ko not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
JPS63501172A (ja) | 1988-04-28 |
JP2591738B2 (ja) | 1997-03-19 |
EP0233939A1 (de) | 1987-09-02 |
WO1987001206A1 (en) | 1987-02-26 |
US4868130A (en) | 1989-09-19 |
CA1292092C (en) | 1991-11-12 |
KR880700269A (ko) | 1988-02-22 |
EP0233939B1 (de) | 1991-11-13 |
DE3682502D1 (de) | 1991-12-19 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
UEP | Publication of translation of european patent specification | ||
REN | Ceased due to non-payment of the annual fee |