ATE59646T1 - 4-brommethyl-5-methyl-1,3-dioxolen-2 -on und verfahren zu seiner herstellung. - Google Patents
4-brommethyl-5-methyl-1,3-dioxolen-2 -on und verfahren zu seiner herstellung.Info
- Publication number
- ATE59646T1 ATE59646T1 AT87103766T AT87103766T ATE59646T1 AT E59646 T1 ATE59646 T1 AT E59646T1 AT 87103766 T AT87103766 T AT 87103766T AT 87103766 T AT87103766 T AT 87103766T AT E59646 T1 ATE59646 T1 AT E59646T1
- Authority
- AT
- Austria
- Prior art keywords
- dioxolen
- group
- methyl
- preparation
- chem
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D307/40—Radicals substituted by oxygen atoms
- C07D307/46—Doubly bound oxygen atoms, or two oxygen atoms singly bound to the same carbon atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
- C07D317/32—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D317/34—Oxygen atoms
- C07D317/40—Vinylene carbonate; Substituted vinylene carbonates
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
- C07D317/62—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to atoms of the carbocyclic ring
- C07D317/64—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Saccharide Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP55058510A JPS6019908B2 (ja) | 1980-04-30 | 1980-04-30 | 1,3−ジオキソレン−2−オン誘導体 |
EP87103766A EP0237084B1 (de) | 1980-04-30 | 1981-04-29 | 4-Brommethyl-5-methyl-1,3-dioxolen-2 -on und Verfahren zu seiner Herstellung |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE59646T1 true ATE59646T1 (de) | 1991-01-15 |
Family
ID=13086410
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT81103232T ATE10939T1 (de) | 1980-04-30 | 1981-04-29 | Verwendung von 1,3-dioxolen-2-on-derivaten. |
AT83102898T ATE34572T1 (de) | 1980-04-30 | 1981-04-29 | 1,3-dioxolen-2-on derivate und verfahren zu deren herstellung. |
AT87103766T ATE59646T1 (de) | 1980-04-30 | 1981-04-29 | 4-brommethyl-5-methyl-1,3-dioxolen-2 -on und verfahren zu seiner herstellung. |
Family Applications Before (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT81103232T ATE10939T1 (de) | 1980-04-30 | 1981-04-29 | Verwendung von 1,3-dioxolen-2-on-derivaten. |
AT83102898T ATE34572T1 (de) | 1980-04-30 | 1981-04-29 | 1,3-dioxolen-2-on derivate und verfahren zu deren herstellung. |
Country Status (7)
Country | Link |
---|---|
US (1) | US4342693A (de) |
EP (3) | EP0090344B1 (de) |
JP (1) | JPS6019908B2 (de) |
AT (3) | ATE10939T1 (de) |
AU (1) | AU536686B2 (de) |
CA (1) | CA1168251A (de) |
DE (2) | DE3177239D1 (de) |
Families Citing this family (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5869876A (ja) * | 1981-07-13 | 1983-04-26 | メルク・エンド・カムパニ−・インコ−ポレ−テツド | (5−アルキル−2−オキソ−1,3−ジオキソレン−4−イル)メチルエステル基を用いたカルボン酸医薬の経口吸収増大 |
US4654331A (en) * | 1981-07-13 | 1987-03-31 | Merck & Co., Inc. | Oral absorption enhancement of carboxylic acid pharmaceuticals using (5-alkyl-2-oxo-1,3-dioxolen-4-yl)methyl ester group |
GR76525B (de) * | 1981-07-13 | 1984-08-10 | Merck & Co Inc | |
US4479947A (en) * | 1981-07-13 | 1984-10-30 | Merck & Co., Inc. | Oral absorption enhancement of carboxylic acid pharmaceuticals using (5-alkyl-2-oxo-1,3-dioxolen-4-yl)methyl ester group |
JPS5874677A (ja) * | 1981-10-30 | 1983-05-06 | Kanebo Ltd | 臭素化1,3−ジオキソレン−2−オン類の製造法 |
JPS5921692A (ja) * | 1982-07-29 | 1984-02-03 | Sankyo Co Ltd | 経口ペネム化合物及びその製法 |
US4555579A (en) * | 1983-03-24 | 1985-11-26 | E. R. Squibb & Sons, Inc. | Dioxolenylmethyl ester prodrugs of phosphinic acid ace inhibitors |
JPS59212488A (ja) * | 1983-05-18 | 1984-12-01 | Kyoto Yakuhin Kogyo Kk | ジオキソ−ル誘導体 |
US4536393A (en) * | 1983-06-06 | 1985-08-20 | Pfizer Inc. | 6-(Aminomethyl)penicillanic acid 1,1-dioxide esters and intermediates therefor |
JPS59231082A (ja) * | 1983-06-14 | 1984-12-25 | Kanebo Ltd | 4−クロロ−4−メチル−5−メチレン−1,3−ジオキソラン−2−オン |
US4521533A (en) * | 1984-07-12 | 1985-06-04 | Pfizer Inc. | Salts of 6-alpha-(aminomethyl)penicillanic acid 1,1-dioxide esters and beta-lactam antibiotics |
US4675186A (en) | 1985-04-18 | 1987-06-23 | Pfizer Inc. | 6-(1-acyl-1-hydroxymethyl)penicillanic acid derivatives |
US4777267A (en) * | 1986-02-07 | 1988-10-11 | Kanebo Ltd. | 1,3-dioxol-2-one derivatives |
US4985456A (en) * | 1986-08-07 | 1991-01-15 | Mikasa Seiyaku Co., Ltd. | 2-anilinophenylacetic acid derivative |
ATE186537T1 (de) * | 1990-08-20 | 1999-11-15 | Suntory Ltd | Antibakterielle penem-ester derivate |
AU652954B2 (en) * | 1990-08-20 | 1994-09-15 | Asubio Pharma Co., Ltd. | Antibacterial penem esters derivatives |
US5616599A (en) * | 1991-02-21 | 1997-04-01 | Sankyo Company, Limited | Angiotensin II antagosist 1-biphenylmethylimidazole compounds and their therapeutic use |
JP3501484B2 (ja) * | 1992-12-17 | 2004-03-02 | 三共株式会社 | ビフェニル誘導体 |
DE19920551A1 (de) * | 1999-05-05 | 2000-11-09 | Bayer Ag | Substituierte Benzimidazole, ihre Herstellung und ihre Verwendung als Mittel gegen parasitäre Protozoen |
WO2008059367A1 (en) * | 2006-11-14 | 2008-05-22 | Pfizer Products Inc. | Penem prodrugs |
CN104230878A (zh) * | 2014-09-26 | 2014-12-24 | 六安科瑞达新型材料有限公司 | 4-氯甲基-5-甲基-1,3-二氧杂环戊烯-2-酮的制备方法 |
CN115772150A (zh) * | 2022-11-10 | 2023-03-10 | 广州理文科技有限公司 | 一种碳酸乙烯酯氟代衍生物的制备方法 |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3020290A (en) * | 1959-10-14 | 1962-02-06 | Jefferson Chem Co Inc | Preparation of unsaturated compounds |
-
1980
- 1980-04-30 JP JP55058510A patent/JPS6019908B2/ja not_active Expired
-
1981
- 1981-04-27 US US06/257,564 patent/US4342693A/en not_active Expired - Lifetime
- 1981-04-28 CA CA000376391A patent/CA1168251A/en not_active Expired
- 1981-04-29 EP EP83102898A patent/EP0090344B1/de not_active Expired
- 1981-04-29 AT AT81103232T patent/ATE10939T1/de not_active IP Right Cessation
- 1981-04-29 AU AU69988/81A patent/AU536686B2/en not_active Ceased
- 1981-04-29 AT AT83102898T patent/ATE34572T1/de not_active IP Right Cessation
- 1981-04-29 DE DE8787103766T patent/DE3177239D1/de not_active Expired - Fee Related
- 1981-04-29 AT AT87103766T patent/ATE59646T1/de not_active IP Right Cessation
- 1981-04-29 DE DE8181103232T patent/DE3167908D1/de not_active Expired
- 1981-04-29 EP EP87103766A patent/EP0237084B1/de not_active Expired - Lifetime
- 1981-04-29 EP EP81103232A patent/EP0039477B1/de not_active Expired
Also Published As
Publication number | Publication date |
---|---|
EP0237084A2 (de) | 1987-09-16 |
JPS6019908B2 (ja) | 1985-05-18 |
DE3177239D1 (de) | 1991-02-07 |
DE3167908D1 (de) | 1985-02-07 |
EP0237084A3 (en) | 1987-09-30 |
JPS5726684A (en) | 1982-02-12 |
US4342693A (en) | 1982-08-03 |
ATE34572T1 (de) | 1988-06-15 |
EP0090344A1 (de) | 1983-10-05 |
EP0090344B1 (de) | 1988-05-25 |
AU536686B2 (en) | 1984-05-17 |
EP0039477B1 (de) | 1984-12-27 |
EP0039477A1 (de) | 1981-11-11 |
CA1168251A (en) | 1984-05-29 |
ATE10939T1 (de) | 1985-01-15 |
AU6998881A (en) | 1981-11-05 |
EP0237084B1 (de) | 1991-01-02 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ATE59646T1 (de) | 4-brommethyl-5-methyl-1,3-dioxolen-2 -on und verfahren zu seiner herstellung. | |
ATE67497T1 (de) | Verfahren zur herstellung von thiazolidinedionderivaten. | |
GB1312536A (en) | Hydantoin derivatives | |
ATE21699T1 (de) | Verfahren zur herstellung von 2-penemverbindungen. | |
ATE87925T1 (de) | Erythromycin-a-derivate und verfahren zu ihrer herstellung. | |
DE3767351D1 (de) | Sialosylceramide und verfahren zu deren herstellung. | |
ATE10838T1 (de) | 4-substituierte 2-oxoazetidin-verbindungen, verfahren zu deren herstellung und ihre verwendung zur antibiotika-herstellung. | |
ATE86860T1 (de) | Praeparat gegen ulcus. | |
ATE67199T1 (de) | Benzoxazin-derivate und verfahren zu ihrer herstellung. | |
ATE77818T1 (de) | Neue naphthylderivate, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung. | |
ATE57183T1 (de) | Herstellung von substituierten gammabutyrolactonen, verwendbar als zwischenprodukte zur herstellung von fungiziden imidazolen und triazolen. | |
ES8100802A1 (es) | Procedimiento para la preparacion de azolilcetales | |
ATE18667T1 (de) | Aethenylimidazol-derivate, verfahren zu deren herstellung und deren pharmazeutische zusammensetzungen, bei deren herstellung verwendbare zwischenprodukte und verfahren zu deren herstellung. | |
DE3866148D1 (de) | Chinolincarbonsaeure-derivate, diese enthaltende zusammensetzung, verfahren zu ihrer herstellung und ihre verwendung zur herstellung von medikamenten. | |
ATE115567T1 (de) | Verfahren zur herstellung von halogensulfonyl- substituierten pyridinen. | |
ATE27606T1 (de) | 7-alpha-acylthio-15,16-methylen-3-oxo-17-alphapregna-1,4-dien-21,17-carbolaktone, verfahren zu deren herstellung und verwendung in arzneimitteln. | |
ATE38665T1 (de) | Verfahren zur herstellung von 5-perfluoralkyl-5,6-dihydrouracyl-derivaten und verwendbare zwischenprodukte. | |
FR2383175A1 (fr) | Procede de preparation de derives de phenylpyridazinone | |
DE69119714D1 (de) | Verfahren zur Herstellung von Benzylphthalazinonderivaten und von deren Salzen | |
DE3777464D1 (de) | Fluorine enthaltende vitamin-d3-derivate und verfahren zu ihrer herstellung. | |
ATE28749T1 (de) | Verfahren zur herstellung von 3,4-dihydro-alpha- pyronen. | |
ATE222T1 (de) | Bis-(2,4-dinitrophenyl)-m ethyl-pyridinium-verbindungen, verfahren zu ihrer herstellung und ihre verwendung als ph-indikatoren. | |
ATE36321T1 (de) | (bis(substituiertes methyl)methyl>isochinolinderivate, verfahren zu ihrer herstellung und pharmazeutische zubereitungen, die sie enthalten. | |
ATE17851T1 (de) | Imidazolylkarbonsaeure, deren derivate und herstellung. | |
ATE92074T1 (de) | Beta-d-phenylthioxyloside, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel. |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
UEP | Publication of translation of european patent specification | ||
REN | Ceased due to non-payment of the annual fee |