ATE553769T1 - Inhibitoren der malt1-proteolytischen aktivität und ihre verwendung - Google Patents

Inhibitoren der malt1-proteolytischen aktivität und ihre verwendung

Info

Publication number
ATE553769T1
ATE553769T1 AT08852880T AT08852880T ATE553769T1 AT E553769 T1 ATE553769 T1 AT E553769T1 AT 08852880 T AT08852880 T AT 08852880T AT 08852880 T AT08852880 T AT 08852880T AT E553769 T1 ATE553769 T1 AT E553769T1
Authority
AT
Austria
Prior art keywords
inhibitors
see seq
malt1 proteolytic
proteolytic activity
relates
Prior art date
Application number
AT08852880T
Other languages
English (en)
Inventor
Rudi Beyaert
Peter Marynen
Thijs Baens
Karen Heyninck
Original Assignee
Vib Vzw
Univ Gent
Univ Leuven Kath
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39186759&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE553769(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Vib Vzw, Univ Gent, Univ Leuven Kath filed Critical Vib Vzw
Application granted granted Critical
Publication of ATE553769T1 publication Critical patent/ATE553769T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/07—Tetrapeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/513—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
    • Y10T436/142222—Hetero-O [e.g., ascorbic acid, etc.]
    • Y10T436/143333—Saccharide [e.g., DNA, etc.]
AT08852880T 2007-11-21 2008-11-20 Inhibitoren der malt1-proteolytischen aktivität und ihre verwendung ATE553769T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US409707P 2007-11-21 2007-11-21
EP07121200 2007-11-21
PCT/EP2008/065925 WO2009065897A2 (en) 2007-11-21 2008-11-20 Inhibitors of malt1 proteolytic activity and uses thereof

Publications (1)

Publication Number Publication Date
ATE553769T1 true ATE553769T1 (de) 2012-05-15

Family

ID=39186759

Family Applications (1)

Application Number Title Priority Date Filing Date
AT08852880T ATE553769T1 (de) 2007-11-21 2008-11-20 Inhibitoren der malt1-proteolytischen aktivität und ihre verwendung

Country Status (6)

Country Link
US (1) US8309523B2 (de)
EP (1) EP2222326B2 (de)
AT (1) ATE553769T1 (de)
AU (1) AU2008327884B2 (de)
CA (1) CA2705694C (de)
WO (1) WO2009065897A2 (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103402516B (zh) * 2010-06-17 2018-01-30 富津世生物技术有限公司 用作抗病毒药物的化合物、组合物及使用方法
EP2465928A1 (de) 2010-12-16 2012-06-20 Academisch Medisch Centrum bij de Universiteit van Amsterdam Behandlung von Th17-vermittelten Krankheiten
EP2744500A1 (de) 2011-08-18 2014-06-25 Nuhope LLC Verbindungen zur verwendung in der krebstherapie
WO2013053765A1 (en) 2011-10-11 2013-04-18 Proyecto De Biomedicina Cima, S.L. A non-human animal model of mucosa-associated lymphoid tissue (malt) lymphoma
WO2014022613A1 (en) * 2012-08-01 2014-02-06 Musc Foundation For Research Development Antibacterial compositions and methods
US9651513B2 (en) * 2012-10-14 2017-05-16 Synaptics Incorporated Fingerprint sensor and button combinations and methods of making same
EP2916656B1 (de) 2012-11-09 2017-10-25 Cornell University Kleinmolekülige malt1-hemmer
SI3149001T1 (sl) 2014-05-28 2019-08-30 Novartis Ag Novi derivati pirazolo pirimidina in njihova uporaba kot inhimitorji malt1
CN108473499B (zh) * 2015-11-13 2021-07-23 诺华股份有限公司 新颖的吡唑并嘧啶衍生物
CN105541806A (zh) * 2015-12-25 2016-05-04 中国药科大学 巴比妥酸类化合物、制备方法及其应用
US10662156B2 (en) 2016-07-29 2020-05-26 Toray Industries, Inc. Guanidine derivative and medical use thereof
CN110312724A (zh) * 2016-07-29 2019-10-08 陆品有限公司 作为malt1抑制剂的取代的噻唑并-吡啶化合物
CR20190110A (es) 2016-07-29 2019-08-27 Lupin Ltd Compuestos de tiazolo-piridina sustituida como inhibidores de malt1
AU2020413333A1 (en) * 2019-12-27 2022-06-16 Schrödinger, Inc. Cyclic compounds and methods of using same

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001055390A1 (en) * 2000-01-28 2001-08-02 Human Genome Sciences, Inc. Human serpin polynucleotides, polypeptides, and antibodies
GB0013655D0 (en) * 2000-06-05 2000-07-26 Prolifix Ltd Therapeutic compounds
AU2003225668A1 (en) * 2002-03-01 2003-09-16 Pintex Pharmaceutical, Inc. Pin1-modulating compounds and methods of use thereof
US20040110145A1 (en) * 2002-12-09 2004-06-10 Isis Pharmaceuticals Inc. Modulation of MALT1 expression
US20070203236A1 (en) * 2006-01-11 2007-08-30 Smith Jeffrey W Novel antagonists of the human fatty acid synthase thioesterase
WO2008146259A2 (en) † 2007-06-01 2008-12-04 University Of Lausanne Malt1 specific cleavage in assay and screening method

Also Published As

Publication number Publication date
WO2009065897A3 (en) 2010-09-23
EP2222326B1 (de) 2012-04-18
AU2008327884B2 (en) 2013-01-24
CA2705694C (en) 2015-02-24
CA2705694A1 (en) 2009-05-28
WO2009065897A2 (en) 2009-05-28
EP2222326A2 (de) 2010-09-01
US8309523B2 (en) 2012-11-13
EP2222326B2 (de) 2015-02-25
AU2008327884A1 (en) 2009-05-28
US20110021548A1 (en) 2011-01-27

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