DK1009834T3 - Regulering af proteinsekretion - Google Patents
Regulering af proteinsekretionInfo
- Publication number
- DK1009834T3 DK1009834T3 DK98941592T DK98941592T DK1009834T3 DK 1009834 T3 DK1009834 T3 DK 1009834T3 DK 98941592 T DK98941592 T DK 98941592T DK 98941592 T DK98941592 T DK 98941592T DK 1009834 T3 DK1009834 T3 DK 1009834T3
- Authority
- DK
- Denmark
- Prior art keywords
- normally
- regulation
- mammalian
- secreted
- protein secretion
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/795—Porphyrin- or corrin-ring-containing peptides
- C07K14/805—Haemoglobins; Myoglobins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/62—DNA sequences coding for fusion proteins
- C12N15/625—DNA sequences coding for fusion proteins containing a sequence coding for a signal sequence
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/04—Fusion polypeptide containing a localisation/targetting motif containing an ER retention signal such as a C-terminal HDEL motif
Landscapes
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Gastroenterology & Hepatology (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9718908.8A GB9718908D0 (en) | 1997-09-05 | 1997-09-05 | Proteins |
| PCT/GB1998/002664 WO1999013090A1 (en) | 1997-09-05 | 1998-09-04 | Regulation of protein secretion |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1009834T3 true DK1009834T3 (da) | 2007-02-12 |
Family
ID=10818638
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK98941592T DK1009834T3 (da) | 1997-09-05 | 1998-09-04 | Regulering af proteinsekretion |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US6881832B1 (da) |
| EP (1) | EP1009834B1 (da) |
| JP (1) | JP4436563B2 (da) |
| AT (1) | ATE344327T1 (da) |
| AU (1) | AU8991098A (da) |
| DE (1) | DE69836336T2 (da) |
| DK (1) | DK1009834T3 (da) |
| ES (1) | ES2273435T3 (da) |
| GB (1) | GB9718908D0 (da) |
| WO (1) | WO1999013090A1 (da) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1897552B1 (en) * | 2003-04-18 | 2009-06-17 | Biogen Idec MA Inc. | Polymer-conjugated glycosylated neublastin |
| GB0314856D0 (en) * | 2003-06-25 | 2003-07-30 | Unitargeting Res As | Protein expression system |
| US7598059B2 (en) | 2003-10-02 | 2009-10-06 | Biogen Idec Ma Inc. | Neublastin expression constructs |
| WO2006023782A2 (en) | 2004-08-19 | 2006-03-02 | Biogen Ideca Ma Inc. | Refolding transforming growth factor beta family proteins |
| TWI501774B (zh) | 2006-02-27 | 2015-10-01 | Biogen Idec Inc | 神經性病症之治療 |
| US20090075925A1 (en) * | 2006-11-16 | 2009-03-19 | Smith Harold C | Methods and Compositions Related to APOBEC-1 Expression |
| ES2476253T3 (es) | 2007-05-01 | 2014-07-14 | Biogen Idec Ma Inc. | P�ptidos de neublastina para su uso en el aumento de la vascularizaci�n en tejido con flujo sanguíneo deteriorado |
| SG10201607962RA (en) | 2012-03-27 | 2016-11-29 | Curevac Ag | Artificial nucleic acid molecules |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3540505C2 (de) | 1985-11-15 | 1995-11-09 | Natronag Verpackung | Sackfüllmaschine |
| AU613876B2 (en) * | 1986-10-01 | 1991-08-15 | Merck & Co., Inc. | Synthetic genes encoding proteins from plasmid containing eucaryotic secretory signal peptides and process for secreting encoded proteins |
| EP0832981A1 (en) * | 1987-02-17 | 1998-04-01 | Pharming B.V. | DNA sequences to target proteins to the mammary gland for efficient secretion |
| WO1991013151A1 (en) * | 1990-02-22 | 1991-09-05 | Biogen, Inc. | Improved expression of polypeptides |
| WO1993004165A1 (en) * | 1991-08-13 | 1993-03-04 | Wisconsin Milk Marketing Board | DNA SEQUENCE ENCODING BOVINE α-LACTALBUMIN AND METHODS OF USE |
-
1997
- 1997-09-05 GB GBGB9718908.8A patent/GB9718908D0/en active Pending
-
1998
- 1998-09-04 DK DK98941592T patent/DK1009834T3/da active
- 1998-09-04 JP JP2000510875A patent/JP4436563B2/ja not_active Expired - Fee Related
- 1998-09-04 EP EP98941592A patent/EP1009834B1/en not_active Expired - Lifetime
- 1998-09-04 AT AT98941592T patent/ATE344327T1/de active
- 1998-09-04 WO PCT/GB1998/002664 patent/WO1999013090A1/en active IP Right Grant
- 1998-09-04 AU AU89910/98A patent/AU8991098A/en not_active Abandoned
- 1998-09-04 DE DE69836336T patent/DE69836336T2/de not_active Expired - Lifetime
- 1998-09-04 ES ES98941592T patent/ES2273435T3/es not_active Expired - Lifetime
-
2000
- 2000-03-02 US US09/518,190 patent/US6881832B1/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| GB9718908D0 (en) | 1997-11-12 |
| EP1009834B1 (en) | 2006-11-02 |
| US6881832B1 (en) | 2005-04-19 |
| JP4436563B2 (ja) | 2010-03-24 |
| ES2273435T3 (es) | 2007-05-01 |
| ATE344327T1 (de) | 2006-11-15 |
| DE69836336D1 (de) | 2006-12-14 |
| WO1999013090A1 (en) | 1999-03-18 |
| JP2001515725A (ja) | 2001-09-25 |
| DE69836336T2 (de) | 2007-05-24 |
| AU8991098A (en) | 1999-03-29 |
| EP1009834A1 (en) | 2000-06-21 |
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