ATE545407T1 - Pharmazeutische formulierung von apomorphin für die bukkale verabreichung - Google Patents
Pharmazeutische formulierung von apomorphin für die bukkale verabreichungInfo
- Publication number
- ATE545407T1 ATE545407T1 AT06727033T AT06727033T ATE545407T1 AT E545407 T1 ATE545407 T1 AT E545407T1 AT 06727033 T AT06727033 T AT 06727033T AT 06727033 T AT06727033 T AT 06727033T AT E545407 T1 ATE545407 T1 AT E545407T1
- Authority
- AT
- Austria
- Prior art keywords
- apomorphine
- buccal administration
- pharmaceutical formulation
- formulation
- pharmaceutically acceptable
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/473—Quinolines; Isoquinolines ortho- or peri-condensed with carbocyclic ring systems, e.g. acridines, phenanthridines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Physiology (AREA)
- Nutrition Science (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Gynecology & Obstetrics (AREA)
- Dispersion Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Psychology (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB0509317.4A GB0509317D0 (en) | 2005-05-06 | 2005-05-06 | Pharmaceutical formulation of apomorphine |
PCT/GB2006/001665 WO2006120412A1 (en) | 2005-05-06 | 2006-05-08 | Pharmaceutical formulation of apomorphine for buccal administration |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE545407T1 true ATE545407T1 (de) | 2012-03-15 |
Family
ID=34685218
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT06727033T ATE545407T1 (de) | 2005-05-06 | 2006-05-08 | Pharmazeutische formulierung von apomorphin für die bukkale verabreichung |
Country Status (21)
Country | Link |
---|---|
US (2) | US20090023766A1 (de) |
EP (1) | EP1885333B1 (de) |
JP (1) | JP5116665B2 (de) |
KR (1) | KR101365458B1 (de) |
CN (1) | CN101217936A (de) |
AT (1) | ATE545407T1 (de) |
AU (1) | AU2006245564A1 (de) |
BR (1) | BRPI0611258A2 (de) |
CA (1) | CA2607802C (de) |
DK (1) | DK1885333T3 (de) |
ES (1) | ES2383433T3 (de) |
GB (1) | GB0509317D0 (de) |
HK (1) | HK1113086A1 (de) |
IL (1) | IL187183A0 (de) |
MX (1) | MX2007013890A (de) |
NO (1) | NO339404B1 (de) |
PT (1) | PT1885333E (de) |
RU (1) | RU2007140701A (de) |
SI (1) | SI1885333T1 (de) |
WO (1) | WO2006120412A1 (de) |
ZA (1) | ZA200709474B (de) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB0819530D0 (en) * | 2008-10-24 | 2008-12-03 | Univ Sheffield | Methods and compositions |
EA025054B1 (ru) * | 2009-06-12 | 2016-11-30 | Сайнэпсус Терапьютикс, Инк. | Единичная дозированная форма для сублингвального введения, включающая частицы апоморфина, для лечения болезни паркинсона или половой дисфункции |
KR101890317B1 (ko) | 2010-12-16 | 2018-08-22 | 선오비온 파마슈티컬스 인코포레이티드 | 설하 필름 |
EP2545788A1 (de) * | 2011-07-13 | 2013-01-16 | Martin Hulliger | Diätisches Mehrkomponentensystem |
US20150328258A1 (en) * | 2012-05-30 | 2015-11-19 | Ibh Ventures, Llc | Polyphenol-reactive oxygen species compositions and methods |
CN104349768B (zh) | 2012-06-05 | 2017-11-07 | 纽罗德姆有限公司 | 包含阿朴***和有机酸的组合物及其用途 |
CA2930410A1 (en) | 2013-11-11 | 2015-05-14 | Impax Laboratories, Inc. | Rapidly disintegrating formulations and methods of use |
JP6042794B2 (ja) * | 2013-12-03 | 2016-12-14 | 本田技研工業株式会社 | 車両制御方法 |
EP3177270A4 (de) * | 2014-08-07 | 2018-01-24 | Mucodel Pharma LLC | Chemisch stabile und oromukusal absorbierbare gelzusammensetzungen eines wirkstoffes in einem mehrkammerabgabesystem |
US10493027B2 (en) | 2014-08-07 | 2019-12-03 | Mucodel Pharma Llc | Chemically stable compositions of a pharmaceutical active agent in a multi- chambered delivery system for mucosal delivery |
EP3285771A4 (de) | 2015-04-21 | 2018-12-05 | Sunovion Pharmaceuticals Inc. | Verfahren zur behandlung von morbus parkinson durch verabreichung von apomorphin an eine mundschleimhaut |
EP3355887A1 (de) | 2015-09-28 | 2018-08-08 | EVER Neuro Pharma GmbH | Wässrige zusammensetzung von apomorphin zur subkutanen verabreichung |
WO2018148382A1 (en) * | 2017-02-10 | 2018-08-16 | Mucodel Pharma Llc | Chemically stable compositions of a pharmaceutical active agent in a multi-chambered delivery system for mucosal delivery |
GB201912686D0 (en) * | 2019-09-04 | 2019-10-16 | Reown Pharma Inc | Pharmaceutical composition |
WO2023012736A1 (en) * | 2021-08-05 | 2023-02-09 | Zydus Lifesciences Limited | Stable pharmaceutical compositions of apomorphine |
WO2023242355A1 (en) | 2022-06-15 | 2023-12-21 | Ever Neuro Pharma Gmbh | Apomorphine prodrugs and uses thereof |
Family Cites Families (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE290864T1 (de) * | 1993-03-26 | 2005-04-15 | Franciscus Wilhelmus He Merkus | Pharmazeutische zusammensetzungen zur intranasalen verabreichung von dihydroergotamin |
US6121276A (en) * | 1994-04-22 | 2000-09-19 | Pentech Pharmaceuticals, Inc. | Apomorphine-containing dosage forms for ameliorating male erectile dysfunction |
GB9517062D0 (en) * | 1995-08-18 | 1995-10-25 | Scherer Ltd R P | Pharmaceutical compositions |
IL132169A0 (en) * | 1997-04-28 | 2001-03-19 | Univ British Columbia | Method and composition for modulating amyloidosis |
US6436950B1 (en) * | 1998-08-14 | 2002-08-20 | Nastech Pharmaceutical Company, Inc. | Nasal delivery of apomorphine |
CZ20022245A3 (cs) * | 1999-12-30 | 2002-10-16 | Tap Holdings, Inc. | Orální mukózní dávkovací formy apomorfinu |
US6974806B2 (en) * | 2000-07-13 | 2005-12-13 | Takeda Pharmaceutical Company Limited | Lipid-rich plaque inhibitors |
US20040028613A1 (en) * | 2001-06-25 | 2004-02-12 | Nastech Pharmaceutical Company Inc | Dopamine agonist formulations for enhanced central nervous system delivery |
US20030068356A1 (en) * | 2001-07-10 | 2003-04-10 | Pather S. Indiran | Sequential drug delivery systems |
CA2487712A1 (en) * | 2002-06-28 | 2004-01-08 | Nastech Pharmaceutical Company Inc. | Compositions and methods for modulating physiology of epithelial junctional adhesion molecules for enhanced mucosal delivery of therapeutic compounds |
SE0202365D0 (sv) * | 2002-08-05 | 2002-08-05 | Pharmacia Ab | New formulation and use thereof |
US20040126448A1 (en) * | 2002-08-05 | 2004-07-01 | Nils-Olof Lindberg | Sexual dysfunction compounds |
GB0403938D0 (en) * | 2004-02-21 | 2004-03-24 | West Pharm Serv Drug Res Ltd | Chitosan containing solution |
-
2005
- 2005-05-06 GB GBGB0509317.4A patent/GB0509317D0/en not_active Ceased
-
2006
- 2006-05-08 AT AT06727033T patent/ATE545407T1/de active
- 2006-05-08 WO PCT/GB2006/001665 patent/WO2006120412A1/en active Application Filing
- 2006-05-08 SI SI200631322T patent/SI1885333T1/sl unknown
- 2006-05-08 DK DK06727033.0T patent/DK1885333T3/da active
- 2006-05-08 CA CA2607802A patent/CA2607802C/en not_active Expired - Fee Related
- 2006-05-08 PT PT06727033T patent/PT1885333E/pt unknown
- 2006-05-08 CN CNA2006800247101A patent/CN101217936A/zh active Pending
- 2006-05-08 EP EP06727033A patent/EP1885333B1/de active Active
- 2006-05-08 ES ES06727033T patent/ES2383433T3/es active Active
- 2006-05-08 BR BRPI0611258-7A patent/BRPI0611258A2/pt not_active IP Right Cessation
- 2006-05-08 MX MX2007013890A patent/MX2007013890A/es active IP Right Grant
- 2006-05-08 AU AU2006245564A patent/AU2006245564A1/en not_active Abandoned
- 2006-05-08 KR KR1020077028422A patent/KR101365458B1/ko active IP Right Grant
- 2006-05-08 RU RU2007140701/15A patent/RU2007140701A/ru not_active Application Discontinuation
- 2006-05-08 US US11/919,799 patent/US20090023766A1/en not_active Abandoned
- 2006-05-08 JP JP2008509511A patent/JP5116665B2/ja not_active Expired - Fee Related
-
2007
- 2007-11-02 ZA ZA200709474A patent/ZA200709474B/xx unknown
- 2007-11-05 IL IL187183A patent/IL187183A0/en unknown
- 2007-12-03 NO NO20076219A patent/NO339404B1/no not_active IP Right Cessation
-
2008
- 2008-06-26 HK HK08107124.6A patent/HK1113086A1/xx not_active IP Right Cessation
-
2012
- 2012-11-05 US US13/669,148 patent/US8772309B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
SI1885333T1 (sl) | 2012-07-31 |
ZA200709474B (en) | 2008-12-31 |
KR20080016608A (ko) | 2008-02-21 |
DK1885333T3 (da) | 2012-05-14 |
US20130131098A1 (en) | 2013-05-23 |
CA2607802C (en) | 2015-02-10 |
US8772309B2 (en) | 2014-07-08 |
MX2007013890A (es) | 2008-04-04 |
JP5116665B2 (ja) | 2013-01-09 |
CA2607802A1 (en) | 2006-11-16 |
ES2383433T3 (es) | 2012-06-21 |
BRPI0611258A2 (pt) | 2010-11-23 |
NO20076219L (no) | 2007-12-03 |
NO339404B1 (no) | 2016-12-12 |
RU2007140701A (ru) | 2009-06-20 |
WO2006120412A1 (en) | 2006-11-16 |
IL187183A0 (en) | 2008-02-09 |
KR101365458B1 (ko) | 2014-02-19 |
CN101217936A (zh) | 2008-07-09 |
EP1885333A1 (de) | 2008-02-13 |
US20090023766A1 (en) | 2009-01-22 |
GB0509317D0 (en) | 2005-06-15 |
JP2008540392A (ja) | 2008-11-20 |
PT1885333E (pt) | 2012-05-14 |
EP1885333B1 (de) | 2012-02-15 |
AU2006245564A1 (en) | 2006-11-16 |
HK1113086A1 (en) | 2008-09-26 |
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