ATE534634T1 - 2-phenyl-4-cyclopropyl-pyrimidinderivate - Google Patents
2-phenyl-4-cyclopropyl-pyrimidinderivateInfo
- Publication number
- ATE534634T1 ATE534634T1 AT09730987T AT09730987T ATE534634T1 AT E534634 T1 ATE534634 T1 AT E534634T1 AT 09730987 T AT09730987 T AT 09730987T AT 09730987 T AT09730987 T AT 09730987T AT E534634 T1 ATE534634 T1 AT E534634T1
- Authority
- AT
- Austria
- Prior art keywords
- cyclopropyl
- phenyl
- pyrimidine derivatives
- pyrimidine
- derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IB2008051389 | 2008-04-11 | ||
PCT/IB2009/051498 WO2009125365A1 (en) | 2008-04-11 | 2009-04-09 | 2-phenyl-4-cyclopropyl-pyrimidine derivatives |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE534634T1 true ATE534634T1 (de) | 2011-12-15 |
Family
ID=40790423
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT09730987T ATE534634T1 (de) | 2008-04-11 | 2009-04-09 | 2-phenyl-4-cyclopropyl-pyrimidinderivate |
Country Status (17)
Country | Link |
---|---|
US (1) | US8466156B2 (de) |
EP (1) | EP2283011B1 (de) |
JP (1) | JP5374578B2 (de) |
KR (1) | KR101610417B1 (de) |
CN (1) | CN101998953B (de) |
AR (1) | AR071653A1 (de) |
AT (1) | ATE534634T1 (de) |
AU (1) | AU2009235123A1 (de) |
CA (1) | CA2719569C (de) |
ES (1) | ES2376820T3 (de) |
IL (1) | IL208548A0 (de) |
MA (1) | MA32277B1 (de) |
MX (1) | MX2010010932A (de) |
NZ (1) | NZ589169A (de) |
TW (1) | TW200944516A (de) |
WO (1) | WO2009125365A1 (de) |
ZA (1) | ZA201008052B (de) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TW200640877A (en) | 2005-04-28 | 2006-12-01 | Actelion Pharmaceuticals Ltd | Pyrimidine derivatives |
AR063258A1 (es) | 2006-10-13 | 2009-01-14 | Actelion Pharmaceuticals Ltd | Derivados de 2-aminocarbonil-piridina, una composicion farmaceutica que los contiene y su uso en la preparacion de un medicamento para el tratamiento de trastornos vasculares oclusivos. |
AR063518A1 (es) | 2006-10-25 | 2009-01-28 | Actelion Pharmaceuticals Ltd | Derivados 2-fenil-6-aminocarbonil-pirimidina; composicion farmaceutica; y su uso para tratar y/o prevenir enfermedades vasculares perifericas viscerales, hepaticas y renales, enfermedades cardiovasculares y enfermedades cerebrovasculares asociados con la agregacion de plaquetas, incluyendo trombosis |
RU2483072C2 (ru) | 2007-11-29 | 2013-05-27 | Актелион Фармасьютиклз Лтд | Производные фосфоновой кислоты и их применение в качестве антагонистов рецептора p2y12 |
AR071652A1 (es) | 2008-04-11 | 2010-07-07 | Actelion Pharmaceuticals Ltd | Derivados 2- fenil-piridina substituidos |
SG175075A1 (en) | 2009-04-08 | 2011-11-28 | Actelion Pharmaceuticals Ltd | 6-(3-aza-bicyclo[3.1.0]hex-3-yl)-2-phenyl-pyrimidines as adp receptor antagonists |
ES2469847T3 (es) | 2009-04-22 | 2014-06-20 | Actelion Pharmaceuticals Ltd. | Derivados de tiazol y su uso como antagonistas del receptor P2Y12 |
WO2013033178A1 (en) | 2011-08-30 | 2013-03-07 | University Of Utah Research Foundation | Methods and compositions for treating nephrogenic diabetes insipidus |
CN109715639B (zh) | 2016-09-22 | 2022-04-19 | 爱杜西亚药品有限公司 | 结晶形式 |
MA49887A (fr) | 2017-03-15 | 2020-06-24 | Idorsia Pharmaceuticals Ltd | Administration sous-cutanée d'un antagoniste du récepteur p2y12 |
Family Cites Families (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2020437A1 (en) | 1989-07-05 | 1991-01-06 | Yoshihide Fuse | Cinnamamide derivative |
JPH05303586A (ja) | 1992-04-07 | 1993-11-16 | Nec Corp | 高精度連立一次方程式解析装置 |
AU5414000A (en) | 1999-06-14 | 2001-01-02 | Eli Lilly And Company | Compounds |
US6861424B2 (en) | 2001-06-06 | 2005-03-01 | Schering Aktiengesellschaft | Platelet adenosine diphosphate receptor antagonists |
DE60333866D1 (de) | 2002-12-11 | 2010-09-30 | Bayer Schering Pharma Ag | 2-aminocarbonlyl-chinolin-verbindungen als adenosin diphosphat plättchenrezeptor antagonisten |
WO2004092189A1 (en) | 2003-04-09 | 2004-10-28 | Wyeth | Derivatives of 2-(8,9-dioxo-2,6-diazabicyclo(5.2.0)non-1(7)-en-2-yl)alkyl phosphonic acid and their use as n-methyl-d-aspartate (nmda) recetor antagonists |
TW200640877A (en) * | 2005-04-28 | 2006-12-01 | Actelion Pharmaceuticals Ltd | Pyrimidine derivatives |
AR057836A1 (es) | 2005-10-21 | 2007-12-19 | Actelion Pharmaceuticals Ltd | Piperizinas como agentes contra la malaria |
AR063258A1 (es) | 2006-10-13 | 2009-01-14 | Actelion Pharmaceuticals Ltd | Derivados de 2-aminocarbonil-piridina, una composicion farmaceutica que los contiene y su uso en la preparacion de un medicamento para el tratamiento de trastornos vasculares oclusivos. |
AR063518A1 (es) | 2006-10-25 | 2009-01-28 | Actelion Pharmaceuticals Ltd | Derivados 2-fenil-6-aminocarbonil-pirimidina; composicion farmaceutica; y su uso para tratar y/o prevenir enfermedades vasculares perifericas viscerales, hepaticas y renales, enfermedades cardiovasculares y enfermedades cerebrovasculares asociados con la agregacion de plaquetas, incluyendo trombosis |
MX2009011089A (es) | 2007-04-23 | 2009-10-30 | Sanofi Aventis | Derivados de quinolina-carboxamida en calidad de antagonistas de p2y12. |
RU2483072C2 (ru) | 2007-11-29 | 2013-05-27 | Актелион Фармасьютиклз Лтд | Производные фосфоновой кислоты и их применение в качестве антагонистов рецептора p2y12 |
EP2238127B1 (de) | 2007-12-26 | 2012-08-15 | Sanofi | Pyrazolcarboxamid-derivate als p2y12-antagonisten |
EP2238128B1 (de) | 2007-12-26 | 2012-08-22 | Sanofi | Heterocyclische pyrazolcarboxamide als p2y12-antagonisten |
AR071652A1 (es) | 2008-04-11 | 2010-07-07 | Actelion Pharmaceuticals Ltd | Derivados 2- fenil-piridina substituidos |
SG175075A1 (en) | 2009-04-08 | 2011-11-28 | Actelion Pharmaceuticals Ltd | 6-(3-aza-bicyclo[3.1.0]hex-3-yl)-2-phenyl-pyrimidines as adp receptor antagonists |
ES2469847T3 (es) | 2009-04-22 | 2014-06-20 | Actelion Pharmaceuticals Ltd. | Derivados de tiazol y su uso como antagonistas del receptor P2Y12 |
-
2009
- 2009-04-08 AR ARP090101256A patent/AR071653A1/es unknown
- 2009-04-09 US US12/936,664 patent/US8466156B2/en active Active
- 2009-04-09 AT AT09730987T patent/ATE534634T1/de active
- 2009-04-09 CA CA2719569A patent/CA2719569C/en active Active
- 2009-04-09 MX MX2010010932A patent/MX2010010932A/es unknown
- 2009-04-09 EP EP09730987A patent/EP2283011B1/de active Active
- 2009-04-09 JP JP2011503537A patent/JP5374578B2/ja active Active
- 2009-04-09 ES ES09730987T patent/ES2376820T3/es active Active
- 2009-04-09 NZ NZ589169A patent/NZ589169A/en not_active IP Right Cessation
- 2009-04-09 KR KR1020107024690A patent/KR101610417B1/ko active IP Right Grant
- 2009-04-09 CN CN200980112591.9A patent/CN101998953B/zh active Active
- 2009-04-09 AU AU2009235123A patent/AU2009235123A1/en not_active Abandoned
- 2009-04-09 WO PCT/IB2009/051498 patent/WO2009125365A1/en active Application Filing
- 2009-04-10 TW TW098112082A patent/TW200944516A/zh unknown
-
2010
- 2010-10-07 IL IL208548A patent/IL208548A0/en unknown
- 2010-11-01 MA MA33296A patent/MA32277B1/fr unknown
- 2010-11-10 ZA ZA2010/08052A patent/ZA201008052B/en unknown
Also Published As
Publication number | Publication date |
---|---|
MA32277B1 (fr) | 2011-05-02 |
CA2719569A1 (en) | 2009-10-15 |
ES2376820T3 (es) | 2012-03-20 |
CN101998953B (zh) | 2014-12-17 |
JP2011516539A (ja) | 2011-05-26 |
EP2283011B1 (de) | 2011-11-23 |
US8466156B2 (en) | 2013-06-18 |
CN101998953A (zh) | 2011-03-30 |
CA2719569C (en) | 2016-06-07 |
ZA201008052B (en) | 2012-04-25 |
WO2009125365A1 (en) | 2009-10-15 |
AR071653A1 (es) | 2010-07-07 |
TW200944516A (en) | 2009-11-01 |
IL208548A0 (en) | 2010-12-30 |
AU2009235123A1 (en) | 2009-10-15 |
NZ589169A (en) | 2012-06-29 |
JP5374578B2 (ja) | 2013-12-25 |
MX2010010932A (es) | 2010-11-05 |
US20110028484A1 (en) | 2011-02-03 |
EP2283011A1 (de) | 2011-02-16 |
KR20100132541A (ko) | 2010-12-17 |
KR101610417B1 (ko) | 2016-04-07 |
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