ATE530552T1 - Pyrrolobenzimidazolone und deren verwendung als antiproliferative mittel - Google Patents
Pyrrolobenzimidazolone und deren verwendung als antiproliferative mittelInfo
- Publication number
- ATE530552T1 ATE530552T1 AT05742984T AT05742984T ATE530552T1 AT E530552 T1 ATE530552 T1 AT E530552T1 AT 05742984 T AT05742984 T AT 05742984T AT 05742984 T AT05742984 T AT 05742984T AT E530552 T1 ATE530552 T1 AT E530552T1
- Authority
- AT
- Austria
- Prior art keywords
- pyrrolobenzimidazolones
- antiproliferative agents
- pyrrolobenzimidazolone
- chem
- excessive
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Immunology (AREA)
- Dermatology (AREA)
- Rheumatology (AREA)
- Virology (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Pain & Pain Management (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Urology & Nephrology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP04011703A EP1598353A1 (de) | 2004-05-17 | 2004-05-17 | Pyrrolobenzimidazolone und ihre Verwendung als als antiproliferative Mittel |
PCT/EP2005/052200 WO2005111040A1 (en) | 2004-05-17 | 2005-05-13 | Pyrrolobenzimidazolones and their use as antiproliferative agents |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE530552T1 true ATE530552T1 (de) | 2011-11-15 |
Family
ID=34925029
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT05742984T ATE530552T1 (de) | 2004-05-17 | 2005-05-13 | Pyrrolobenzimidazolone und deren verwendung als antiproliferative mittel |
Country Status (6)
Country | Link |
---|---|
US (1) | US7714010B2 (de) |
EP (2) | EP1598353A1 (de) |
JP (1) | JP4933428B2 (de) |
AT (1) | ATE530552T1 (de) |
CA (1) | CA2569088C (de) |
WO (1) | WO2005111040A1 (de) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1879894A1 (de) | 2005-04-14 | 2008-01-23 | F.Hoffmann-La Roche Ag | Aminopyrazolderivate, ihre herstellung und verwendung als pharmazeutische mittel |
KR20080106284A (ko) * | 2006-03-23 | 2008-12-04 | 에프. 호프만-라 로슈 아게 | 치환된 인다졸 유도체, 이의 제조 및 약학적 제제로서의 용도 |
WO2010077839A1 (en) * | 2008-12-15 | 2010-07-08 | Wyeth Llc (Formerly Known As Wyeth) | Substituted oxindol cb2 agonists for pain treatment |
US9428513B2 (en) * | 2013-11-07 | 2016-08-30 | Boehringer Ingelheim International Gmbh | Triazolopyrazine |
CN103709142B (zh) * | 2013-11-14 | 2019-12-06 | 江苏阿尔法药业有限公司 | 达比加群中间体的制备方法 |
US9428515B2 (en) * | 2014-05-09 | 2016-08-30 | Boehringer Ingelheim International Gmbh | Benzimidazole derivatives |
KR20160066490A (ko) * | 2014-12-02 | 2016-06-10 | 주식회사 씨앤드씨신약연구소 | 헤테로사이클 유도체 및 그의 용도 |
WO2018108627A1 (de) | 2016-12-12 | 2018-06-21 | Bayer Cropscience Aktiengesellschaft | Verwendung substituierter indolinylmethylsulfonamide oder deren salze zur steigerung der stresstoleranz in pflanzen |
CN107474016A (zh) * | 2017-07-03 | 2017-12-15 | 浙江清和新材料科技有限公司 | 一种氨基取代的2‑苯基苯并咪唑类衍生物的合成方法 |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3531678A1 (de) * | 1985-09-05 | 1987-03-12 | Boehringer Mannheim Gmbh | Neue pyrrolo-benzimidazole, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
JPS62145083A (ja) * | 1985-12-18 | 1987-06-29 | Yoshitomi Pharmaceut Ind Ltd | 縮合イミダゾ−ル誘導体 |
DE3639466A1 (de) * | 1986-11-18 | 1988-05-19 | Thomae Gmbh Dr K | Neue pyrrolo-benzimidazole, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung |
DE3642315A1 (de) * | 1986-12-11 | 1988-06-23 | Boehringer Mannheim Gmbh | Neue pyrrolobenzimidazole, verfahren zu ihrer herstellung sowie arzneimittel |
DE3928177A1 (de) * | 1989-04-08 | 1991-02-28 | Thomae Gmbh Dr K | Benzimidazole, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung |
MX9707809A (es) * | 1995-06-07 | 1998-01-31 | Procter & Gamble | Una composicion farmaceutica que contiene bencimidazol para inhibir el crecimiento de canceres. |
US6506783B1 (en) * | 1997-05-16 | 2003-01-14 | The Procter & Gamble Company | Cancer treatments and pharmaceutical compositions therefor |
PE20030758A1 (es) * | 2001-12-05 | 2003-10-07 | Aventis Pharma Sa | 1,3-diarilprop-2-en-1-onas, composiciones que las contienen y su utilizacion |
US20040147584A2 (en) * | 2001-12-05 | 2004-07-29 | Aventis Pharma S.A. | 1,3-diarylprop-2-en-1-ones, compositions containing them and use thereof |
-
2004
- 2004-05-17 EP EP04011703A patent/EP1598353A1/de not_active Withdrawn
-
2005
- 2005-05-13 EP EP05742984A patent/EP1756112B1/de active Active
- 2005-05-13 WO PCT/EP2005/052200 patent/WO2005111040A1/en not_active Application Discontinuation
- 2005-05-13 AT AT05742984T patent/ATE530552T1/de not_active IP Right Cessation
- 2005-05-13 CA CA2569088A patent/CA2569088C/en active Active
- 2005-05-13 JP JP2007517242A patent/JP4933428B2/ja active Active
- 2005-05-17 US US11/130,542 patent/US7714010B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
WO2005111040A1 (en) | 2005-11-24 |
CA2569088A1 (en) | 2005-11-24 |
US20050261350A1 (en) | 2005-11-24 |
US7714010B2 (en) | 2010-05-11 |
JP2008502709A (ja) | 2008-01-31 |
EP1598353A1 (de) | 2005-11-23 |
EP1756112A1 (de) | 2007-02-28 |
JP4933428B2 (ja) | 2012-05-16 |
EP1756112B1 (de) | 2011-10-26 |
CA2569088C (en) | 2012-07-31 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |