ATE526323T1 - Die hiv-protease hemmende verbindungen - Google Patents
Die hiv-protease hemmende verbindungenInfo
- Publication number
- ATE526323T1 ATE526323T1 AT04813910T AT04813910T ATE526323T1 AT E526323 T1 ATE526323 T1 AT E526323T1 AT 04813910 T AT04813910 T AT 04813910T AT 04813910 T AT04813910 T AT 04813910T AT E526323 T1 ATE526323 T1 AT E526323T1
- Authority
- AT
- Austria
- Prior art keywords
- hiv protease
- inhibiting compounds
- protease inhibiting
- disclosed
- hiv
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/28—Radicals substituted by singly-bound oxygen or sulphur atoms
- C07D213/30—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/36—Radicals substituted by singly-bound nitrogen atoms
- C07D213/40—Acylated substituent nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/04—Ortho-condensed systems
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US10/733,946 US20050131017A1 (en) | 2003-12-11 | 2003-12-11 | HIV protease inhibiting compounds |
PCT/US2004/041658 WO2005058841A2 (en) | 2003-12-11 | 2004-12-09 | Hiv protease inhibiting compounds |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE526323T1 true ATE526323T1 (de) | 2011-10-15 |
Family
ID=34653255
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT04813910T ATE526323T1 (de) | 2003-12-11 | 2004-12-09 | Die hiv-protease hemmende verbindungen |
Country Status (10)
Country | Link |
---|---|
US (1) | US20050131017A1 (de) |
EP (2) | EP2266971A3 (de) |
JP (2) | JP5010921B2 (de) |
AT (1) | ATE526323T1 (de) |
CA (1) | CA2549098A1 (de) |
ES (1) | ES2372179T3 (de) |
HK (1) | HK1100659A1 (de) |
MX (1) | MXPA06006612A (de) |
TW (1) | TWI355265B (de) |
WO (1) | WO2005058841A2 (de) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20060058286A1 (en) * | 2004-09-16 | 2006-03-16 | Mark Krystal | Methods of treating HIV infection |
US7786153B2 (en) | 2005-03-02 | 2010-08-31 | Abbott Laboratories Inc. | Compounds that are useful for improving pharmacokinetics |
US7713987B2 (en) * | 2005-12-06 | 2010-05-11 | Rigel Pharmaceuticals, Inc. | Pyrimidine-2,4-diamines and their uses |
WO2007114978A2 (en) * | 2006-02-09 | 2007-10-11 | Boehringer Ingelheim International Gmbh | Method for treating hiv infection through co-administration of tipranavir and pa-457 |
DE102006032589A1 (de) * | 2006-07-13 | 2008-01-17 | Bayer Healthcare Ag | Verfahren zur Herstellung von 5-Formylpyridin-2-carbonitril |
CA2661873A1 (en) | 2006-08-31 | 2008-03-06 | Abbott Laboratories | Cytochrome p450 oxidase inhibitors and uses thereof |
ES2394952T3 (es) | 2007-06-12 | 2013-02-07 | Concert Pharmaceuticals Inc. | Derivados de axapéptido como inhibidores de la proteasa VIH |
WO2009084544A1 (ja) * | 2007-12-27 | 2009-07-09 | Idemitsu Kosan Co., Ltd. | 含窒素複素環誘導体及びそれを用いた有機エレクトロルミネッセンス素子 |
DK2373172T3 (da) | 2008-12-03 | 2013-10-21 | Presidio Pharmaceuticals Inc | Hcv-ns5a-hæmmere |
WO2012007500A2 (de) | 2010-07-15 | 2012-01-19 | Bayer Cropscience Ag | Neue heterocyclische verbindungen als schädlingsbekämpfungsmittel |
US11285142B2 (en) | 2015-09-29 | 2022-03-29 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Compositions and methods for identifying and treating dystonia disorders |
JOP20180009A1 (ar) * | 2017-02-06 | 2019-01-30 | Gilead Sciences Inc | مركبات مثبط فيروس hiv |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB427857A (en) | 1934-08-02 | 1935-05-01 | Newsum Sons & Company Ltd H | A new or improved system of construction for skeleton structures, particularly vehicle body frames and door frames |
US5142056A (en) * | 1989-05-23 | 1992-08-25 | Abbott Laboratories | Retroviral protease inhibiting compounds |
JPH07502970A (ja) * | 1990-06-01 | 1995-03-30 | ザ・デュポン・メルク・ファーマシュウティカル・カンパニー | 1,4―ジアミノ―2,3―ジヒドロキシブタン類 |
IE20010533A1 (en) * | 1990-11-20 | 2003-03-05 | Abbott Lab | Intermediates for preparing retroviral protease inhibiting compounds |
PT1302468E (pt) * | 1992-12-29 | 2009-02-13 | Abbott Lab | Processos e intermediários para o fabrico de compostos inibidores de protease retroviral |
US5763464A (en) * | 1995-11-22 | 1998-06-09 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Retroviral agents containing anthranilamide, substituted benzamide and other subunits, and methods of using same |
JP2000502997A (ja) * | 1995-12-13 | 2000-03-14 | アボツト・ラボラトリーズ | レトロウイルスプロテアーゼ抑制化合物 |
US5914332A (en) * | 1995-12-13 | 1999-06-22 | Abbott Laboratories | Retroviral protease inhibiting compounds |
AU2492500A (en) * | 1999-01-06 | 2000-07-24 | Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The | Aspartic protease inhibitors, compositions, and associated therapeutic methods |
-
2003
- 2003-12-11 US US10/733,946 patent/US20050131017A1/en not_active Abandoned
-
2004
- 2004-12-09 WO PCT/US2004/041658 patent/WO2005058841A2/en active Application Filing
- 2004-12-09 EP EP10179573A patent/EP2266971A3/de not_active Withdrawn
- 2004-12-09 TW TW093138198A patent/TWI355265B/zh not_active IP Right Cessation
- 2004-12-09 EP EP04813910A patent/EP1697344B1/de not_active Not-in-force
- 2004-12-09 AT AT04813910T patent/ATE526323T1/de not_active IP Right Cessation
- 2004-12-09 ES ES04813910T patent/ES2372179T3/es active Active
- 2004-12-09 JP JP2006544070A patent/JP5010921B2/ja not_active Expired - Fee Related
- 2004-12-09 CA CA002549098A patent/CA2549098A1/en not_active Abandoned
- 2004-12-09 MX MXPA06006612A patent/MXPA06006612A/es active IP Right Grant
-
2007
- 2007-02-28 HK HK07102279.1A patent/HK1100659A1/xx not_active IP Right Cessation
-
2012
- 2012-03-06 JP JP2012049246A patent/JP2012162526A/ja not_active Withdrawn
Also Published As
Publication number | Publication date |
---|---|
TWI355265B (en) | 2012-01-01 |
WO2005058841A3 (en) | 2006-03-09 |
JP5010921B2 (ja) | 2012-08-29 |
HK1100659A1 (en) | 2007-09-28 |
EP1697344B1 (de) | 2011-09-28 |
EP2266971A3 (de) | 2011-04-06 |
TW200529809A (en) | 2005-09-16 |
US20050131017A1 (en) | 2005-06-16 |
ES2372179T3 (es) | 2012-01-16 |
WO2005058841A2 (en) | 2005-06-30 |
EP1697344A2 (de) | 2006-09-06 |
JP2012162526A (ja) | 2012-08-30 |
CA2549098A1 (en) | 2005-06-30 |
EP2266971A2 (de) | 2010-12-29 |
JP2007516260A (ja) | 2007-06-21 |
MXPA06006612A (es) | 2006-08-31 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |