ATE517986T1 - Enzymatische umwandlung von roten blutzellen der blutgruppen b und ab unter verwendung von einem alpha-galactosidase mit einzigartigen substratspezifitäten und kinetischen eigenschaften - Google Patents
Enzymatische umwandlung von roten blutzellen der blutgruppen b und ab unter verwendung von einem alpha-galactosidase mit einzigartigen substratspezifitäten und kinetischen eigenschaftenInfo
- Publication number
- ATE517986T1 ATE517986T1 AT02763720T AT02763720T ATE517986T1 AT E517986 T1 ATE517986 T1 AT E517986T1 AT 02763720 T AT02763720 T AT 02763720T AT 02763720 T AT02763720 T AT 02763720T AT E517986 T1 ATE517986 T1 AT E517986T1
- Authority
- AT
- Austria
- Prior art keywords
- galactosidase
- alpha
- blood group
- enzymatic conversion
- substrate specificities
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0641—Erythrocytes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
- C12N1/205—Bacterial isolates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
- C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
- C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
- C12N9/2465—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1) acting on alpha-galactose-glycoside bonds, e.g. alpha-galactosidase (3.2.1.22)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
- C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
- C12Y302/01022—Alpha-galactosidase (3.2.1.22)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
- C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
- C12Y302/01049—Alpha-N-acetylgalactosaminidase (3.2.1.49)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
- C12R2001/465—Streptomyces
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biomedical Technology (AREA)
- Microbiology (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Hematology (AREA)
- Cell Biology (AREA)
- Biophysics (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Virology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Pharmacology & Pharmacy (AREA)
- Diabetes (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US32497001P | 2001-09-25 | 2001-09-25 | |
US36176902P | 2002-03-05 | 2002-03-05 | |
US10/251,271 US7767415B2 (en) | 2001-09-25 | 2002-09-20 | Compositions and methods for modifying blood cell carbohydrates |
PCT/US2002/030403 WO2003027245A2 (en) | 2001-09-25 | 2002-09-25 | CONVERSION OF RED BLOOD CELLS A, B, AND AB USING a-N-ACETYLGALACTOSAMINIDASES AND a-GALACTOSIDASE |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE517986T1 true ATE517986T1 (de) | 2011-08-15 |
Family
ID=27400431
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT02763720T ATE517986T1 (de) | 2001-09-25 | 2002-09-25 | Enzymatische umwandlung von roten blutzellen der blutgruppen b und ab unter verwendung von einem alpha-galactosidase mit einzigartigen substratspezifitäten und kinetischen eigenschaften |
Country Status (7)
Country | Link |
---|---|
US (5) | US7767415B2 (de) |
EP (2) | EP1436387B1 (de) |
JP (2) | JP4371810B2 (de) |
AT (1) | ATE517986T1 (de) |
AU (1) | AU2008203095B2 (de) |
CA (1) | CA2460575C (de) |
WO (1) | WO2003027245A2 (de) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7767415B2 (en) * | 2001-09-25 | 2010-08-03 | Velico Medical, Inc. | Compositions and methods for modifying blood cell carbohydrates |
EA011481B1 (ru) * | 2003-02-17 | 2009-04-28 | Коуд Биотек Лимитид | Эритроциты, имеющие ферментативно уменьшенный уровень экспрессии антигена группы крови системы аво, способ их получения и применение |
US20070287196A1 (en) * | 2004-06-11 | 2007-12-13 | Adeka Corporation | Enzymatic Modification of Cell-Surface H Antigen by Glycosyltransferases |
AU2006272675B2 (en) * | 2005-07-26 | 2012-07-05 | Velico Medical, Inc. | Blood processing device and associated systems and methods |
US20070100557A1 (en) * | 2005-10-24 | 2007-05-03 | Yi Zhang | Selection of genotyped transfusion donors by cross-matching to genotyped recipients |
EP1945269A4 (de) * | 2005-10-31 | 2010-02-17 | Zymequest Inc | Neue a-galactosidasen |
EP2502494A3 (de) * | 2005-10-31 | 2012-12-19 | Velico Medical, Inc. | Neue a-galactosidasen |
US20080207983A1 (en) * | 2007-02-22 | 2008-08-28 | Searete Llc, A Limited Liability Corporation Of The State Of Delaware | Coded-sequence activation of surgical implants |
WO2008136735A1 (en) | 2007-05-04 | 2008-11-13 | Nilsson Kurt G I | Material for separation of a biomolecule |
CN100569942C (zh) * | 2007-11-02 | 2009-12-16 | 中国人民解放军军事医学科学院野战输血研究所 | 一种α-N-乙酰半乳糖胺酶及其编码基因与应用 |
GB0817908D0 (en) | 2008-10-01 | 2008-11-05 | Univ Ghent | Blood group a/b/h determinant on type 1 core glycosphinglipids chain as recognition point for the fedf protein of f18-fimbriated enterotoxigenic |
US9095436B2 (en) | 2009-04-14 | 2015-08-04 | The Invention Science Fund I, Llc | Adjustable orthopedic implant and method for treating an orthopedic condition in a subject |
US9788539B2 (en) | 2011-05-17 | 2017-10-17 | Velico Medical, Inc. | Platelet protection solution having beta-galactosidase and sialidase inhibitors |
CA2887083A1 (en) | 2012-10-05 | 2014-04-10 | Velico Medical, Inc. | Platelet additive solution having a beta-galactosidase inhibitor |
EP3837370A4 (de) * | 2018-08-17 | 2022-09-14 | The University of British Columbia | Enzymatische zusammensetzungen zur spaltung von kohlenhydratantigen, verfahren, verwendungen, vorrichtungen und damit assoziierte systeme |
Family Cites Families (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4209509A (en) * | 1978-02-08 | 1980-06-24 | Meiji Seika Kaisha Ltd. | Substance SF-1739 derivatives, process for preparing the same and antibacterial compositions containing the same |
US4330619A (en) | 1980-08-14 | 1982-05-18 | New York Blood Center, Inc. | Enzymatic conversion of red cells for transfusion |
US4427777A (en) | 1980-08-14 | 1984-01-24 | New York Blood Center, Inc. | Enzymatic conversion of red cells for transfusion |
US4609627A (en) * | 1983-08-01 | 1986-09-02 | New York Blood Center, Inc. | Enzymatic conversion of certain sub-type A and AB erythrocytes |
CA1339101C (en) | 1986-06-03 | 1997-07-29 | Nicolaas Overbeeke | Production of guar alpha-galactosidase and immunologically related alpha-galactosidases by host organisms transformed with recombinant dna methods |
US5382524A (en) | 1990-10-24 | 1995-01-17 | The Mount Sinai School Of Medicine Of The City University Of New York | Cloning and expression of biologically active α-n-acetylgalactosaminidase |
US5401650A (en) | 1990-10-24 | 1995-03-28 | The Mount Sinai School Of Medicine Of The City University Of New York | Cloning and expression of biologically active α-galactosidase A |
WO1994009121A1 (en) | 1992-10-22 | 1994-04-28 | The New York Blood Center, Inc. | Preparation of enzyme for conversion of sub-type a and ab erythrocytes |
WO1994009123A1 (en) | 1992-10-22 | 1994-04-28 | The New York Blood Center, Inc. | Recycling of enzymes used to convert sub-type a, b and ab erythrocytes |
US6228631B1 (en) | 1992-10-22 | 2001-05-08 | New York Blood Center, Inc. | Recombinant α-N-acetylgalactosaminidase enzyme and cDNA encoding said enzyme |
JPH06285701A (ja) | 1993-04-05 | 1994-10-11 | Fanuc Ltd | Nc旋削加工装置 |
US6329191B1 (en) | 1993-08-30 | 2001-12-11 | Hawaii Biotechnology Group, Inc. | DNA encoding recombinant coffee bean alpha-galactosidase |
US6458573B1 (en) | 1993-09-23 | 2002-10-01 | New England Biolabs, Inc. | Isolation and composition of a novel glycosidase from chryseobacterium |
US5633130A (en) | 1994-09-08 | 1997-05-27 | The Curators Of The University Of Missouri | Buffer system for increasing seroconversion efficiency |
US5606042A (en) | 1994-09-08 | 1997-02-25 | The Curators Of The University Of Missouri | Glycine α-D-galactosidases |
US6423525B1 (en) | 1994-09-22 | 2002-07-23 | New England Biolabs, Inc. | Isolation and composition of a novel glycosidase from chryseobacterium |
JPH10513057A (ja) | 1995-01-30 | 1998-12-15 | ニューヨーク・ブラッド・センター・インコーポレイテッド | 組換えα−ガラクトシダーゼ酵素 |
US6184017B1 (en) | 1996-05-08 | 2001-02-06 | The Curators Of The University Of Missouri | Glycine and phaseolus α-D-galactosidases |
US5925541A (en) | 1996-09-11 | 1999-07-20 | New York Blood Center, Inc. | Endo-β-galactosidase |
JP2001505563A (ja) * | 1996-11-21 | 2001-04-24 | ニューヨーク・ブラッド・センター・インコーポレイテッド | 血液型の変換方法 |
AU1298699A (en) | 1997-11-03 | 1999-05-24 | Curators Of The University Of Missouri, The | Alpha-n-acetylgalactosaminidase from (clostridium perfringens) |
US7767415B2 (en) * | 2001-09-25 | 2010-08-03 | Velico Medical, Inc. | Compositions and methods for modifying blood cell carbohydrates |
-
2002
- 2002-09-20 US US10/251,271 patent/US7767415B2/en not_active Expired - Fee Related
- 2002-09-25 AT AT02763720T patent/ATE517986T1/de not_active IP Right Cessation
- 2002-09-25 WO PCT/US2002/030403 patent/WO2003027245A2/en active Application Filing
- 2002-09-25 JP JP2003530817A patent/JP4371810B2/ja not_active Expired - Fee Related
- 2002-09-25 EP EP02763720A patent/EP1436387B1/de not_active Expired - Lifetime
- 2002-09-25 CA CA2460575A patent/CA2460575C/en not_active Expired - Fee Related
- 2002-09-25 EP EP10182388A patent/EP2302045A1/de not_active Withdrawn
-
2005
- 2005-02-02 US US11/049,271 patent/US20050208655A1/en not_active Abandoned
-
2008
- 2008-07-14 AU AU2008203095A patent/AU2008203095B2/en not_active Ceased
-
2009
- 2009-04-01 JP JP2009089619A patent/JP2009153525A/ja not_active Withdrawn
-
2010
- 2010-05-28 US US12/789,946 patent/US7993896B2/en not_active Expired - Fee Related
-
2011
- 2011-08-08 US US13/205,588 patent/US8697411B2/en not_active Expired - Fee Related
-
2014
- 2014-03-07 US US14/201,407 patent/US20140220553A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
WO2003027245A2 (en) | 2003-04-03 |
JP4371810B2 (ja) | 2009-11-25 |
US8697411B2 (en) | 2014-04-15 |
US20120202273A1 (en) | 2012-08-09 |
JP2009153525A (ja) | 2009-07-16 |
AU2008203095B2 (en) | 2012-02-02 |
US20050208655A1 (en) | 2005-09-22 |
EP1436387A4 (de) | 2005-12-21 |
JP2005503808A (ja) | 2005-02-10 |
CA2460575C (en) | 2013-07-30 |
US20140220553A1 (en) | 2014-08-07 |
CA2460575A1 (en) | 2003-04-03 |
US7993896B2 (en) | 2011-08-09 |
US20030157474A1 (en) | 2003-08-21 |
WO2003027245B1 (en) | 2003-08-21 |
EP2302045A1 (de) | 2011-03-30 |
EP1436387A2 (de) | 2004-07-14 |
AU2008203095A1 (en) | 2010-03-18 |
US20110045569A1 (en) | 2011-02-24 |
US7767415B2 (en) | 2010-08-03 |
WO2003027245A3 (en) | 2003-07-10 |
EP1436387B1 (de) | 2011-07-27 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ATE517986T1 (de) | Enzymatische umwandlung von roten blutzellen der blutgruppen b und ab unter verwendung von einem alpha-galactosidase mit einzigartigen substratspezifitäten und kinetischen eigenschaften | |
BR0010989A (pt) | Plantas e células de plantas geneticamente modificadas com uma atividade aumentada de uma proteìna de amilossacarase e uma enzima de ramificação | |
DK1022329T3 (da) | Multienzymatisk sammensætning med glucoamylasisk, proteolytisk og xylanasisk aktivitet samt fremgangsmåde til fremstilling af sammensætningen ved hjælp af aspergillus-gæring i et fast hvedeklidsmedium | |
EP1498485A4 (de) | Zellen mit modifiziertem genom | |
IT1190780B (it) | Prodotto enzimatico deramificante,sua preparazione ed uso | |
WO2004044158A3 (en) | Human embryonic stem cell cultures, and compositions and methods for growing same | |
DE69333067D1 (de) | Enzym mit endoglukanase wirkung | |
WO2003010302A1 (fr) | Construction cellulaire cultivee contenant des spheroides de cellules animales cultivees et utilisation correspondante | |
EP0227264A3 (de) | Transformation und Fremdgenexpression mit holzigen Arten | |
NZ512185A (en) | A method for manufacturing glycoproteins having human- type glycosylation in plant cells | |
WO2003091431A8 (fr) | Methylotrophe produisant une chaine de sucre de type mammifere | |
WO1995010616A3 (en) | USE OF α-1,4-GLUCAN LYASE FOR PREPARATION OF 1,5-D-ANHYDROFRUCTOSE | |
WO2000015764A3 (en) | Propagation and/or derivation of embryonic stem cells | |
WO2003054160A3 (en) | Cell lines with latent immunodeficiency virus and methods of use thereof | |
CA2154944A1 (en) | Thermostable xylanase dna, protein and methods of use | |
CA2219962A1 (en) | C3 plants expressing photosynthetic enzyme of c4 plants | |
MXPA02006094A (es) | Metodos para producir embriones clonadod y adultos a partir de celulas cultivadas. | |
EP0807685A3 (de) | Saccharose-Phosphate-Synthase (SPS), Verfahren zu ihrer Herstellung, ihre cDNA und deren Verwendung von die Expressionsrate von SPS in pflanzlichen Zellen zu verändern | |
CA2119070A1 (en) | Energy-supplementing saccharide source and its uses | |
WO2002058588A3 (en) | Processes for making cryopreserved composite living constructs and products resulting therefrom | |
EP0841397A3 (de) | Trehalose phosphorylase, deren Herstellung und Verwendung | |
AU3609800A (en) | Novel formulations of alkyllithiums with improved thermal stability, processes to produce these formulations and processes for using the same to improve stability of living polymer chain ends | |
WO2000001841A3 (en) | Hyaluronic acid mimics and methods related thereto | |
WO2002034902A3 (en) | Reversibly soluble enzyme-polymer conjugates | |
WO1993023529A3 (fr) | Culture stabilisee d'agregats cellulaires et procede de developpement des embryons a partir d'une souche proembryogene destine a la regeneration de la vigne |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |