WO2000001841A3 - Hyaluronic acid mimics and methods related thereto - Google Patents

Hyaluronic acid mimics and methods related thereto Download PDF

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Publication number
WO2000001841A3
WO2000001841A3 PCT/US1999/015263 US9915263W WO0001841A3 WO 2000001841 A3 WO2000001841 A3 WO 2000001841A3 US 9915263 W US9915263 W US 9915263W WO 0001841 A3 WO0001841 A3 WO 0001841A3
Authority
WO
WIPO (PCT)
Prior art keywords
hyaluronic acid
methods related
acid mimics
mimics
methods
Prior art date
Application number
PCT/US1999/015263
Other languages
French (fr)
Other versions
WO2000001841A2 (en
Inventor
Glenn D Prestwich
Michael Ziebell
Bai Luo
Zhan-Gong Zhao
Original Assignee
Glenn D Prestwich
Michael Ziebell
Bai Luo
Zhao Zhan Gong
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glenn D Prestwich, Michael Ziebell, Bai Luo, Zhao Zhan Gong filed Critical Glenn D Prestwich
Priority to AU49716/99A priority Critical patent/AU4971699A/en
Priority to CA002346742A priority patent/CA2346742A1/en
Priority to EP99933718A priority patent/EP1169048A4/en
Publication of WO2000001841A2 publication Critical patent/WO2000001841A2/en
Publication of WO2000001841A3 publication Critical patent/WO2000001841A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/04—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
    • C07K1/047—Simultaneous synthesis of different peptide species; Peptide libraries
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Cosmetics (AREA)
  • Materials For Medical Uses (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

HA mimics and methods related thereto are disclosed. In particular, mimics with structures determined by virtue of novel methods, and the novel methods are disclosed. The HA mimics are useful for a variety of HA-related uses.
PCT/US1999/015263 1998-07-06 1999-07-06 Hyaluronic acid mimics and methods related thereto WO2000001841A2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
AU49716/99A AU4971699A (en) 1998-07-06 1999-07-06 Hyaluronic acid mimics and methods related thereto
CA002346742A CA2346742A1 (en) 1998-07-06 1999-07-06 Hyaluronic acid mimics and methods related thereto
EP99933718A EP1169048A4 (en) 1998-07-06 1999-07-06 Hyaluronic acid mimics and methods related thereto

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US9175898P 1998-07-06 1998-07-06
US60/091,758 1998-07-06
US34770799A 1999-07-03 1999-07-03
US09/347,707 1999-07-03

Publications (2)

Publication Number Publication Date
WO2000001841A2 WO2000001841A2 (en) 2000-01-13
WO2000001841A3 true WO2000001841A3 (en) 2001-11-08

Family

ID=26784302

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1999/015263 WO2000001841A2 (en) 1998-07-06 1999-07-06 Hyaluronic acid mimics and methods related thereto

Country Status (4)

Country Link
EP (1) EP1169048A4 (en)
AU (1) AU4971699A (en)
CA (1) CA2346742A1 (en)
WO (1) WO2000001841A2 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6852696B2 (en) 1999-03-26 2005-02-08 The University Of Texas System Inhibitors of glycosaminoglycans
CA2448483A1 (en) * 2000-10-05 2002-04-11 Transition Therapeutics Inc. Compositions and methods for treating cellular response to injury and other proliferating cell disorders regulated by hyaladherin and hyaluronans
WO2002076173A2 (en) * 2001-03-21 2002-10-03 The University Of Texas System Inhibitors of glycosaminoglycans
FR2907682B1 (en) 2006-10-26 2012-12-07 Vincience COSMETIC AND / OR PHARMACEUTICAL COMPOSITION COMPRISING AS AN ACTIVE INGREDIENT AT LEAST ONE PEPTIDE AND THE USE OF THIS PEPTIDE.
US20110196035A1 (en) * 2010-02-05 2011-08-11 Kolomytkin Oleg V Temporally-Controlled Treatment of Joint Disease
CN111218452B (en) * 2020-02-25 2022-11-15 芜湖天明生物技术有限公司 Recombinant human TSG-6 gene, recombinant human TSG-6 protein standard, and preparation methods and applications thereof

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4957738A (en) * 1987-01-14 1990-09-18 Patarroyo Manuel E Protein copolymer malaria vaccine
IL88309A0 (en) * 1987-11-17 1989-06-30 Scripps Clinic Res Peptides for use in the purification of factor viii
ES2075016T3 (en) * 1988-08-23 1995-10-01 Dana Farber Cancer Inst Inc THE ALPHA SUBUNIT OF THE RECEPTOR OF ADHERENCE TO LEUKOCYTES LFA-1.
JP3329868B2 (en) * 1992-09-30 2002-09-30 株式会社クラレ Peptide and adsorbent obtained by immobilizing the peptide on a carrier
JPH07138289A (en) * 1993-11-16 1995-05-30 Mitsubishi Chem Corp New peptide
JPH08151396A (en) * 1994-11-28 1996-06-11 Teijin Ltd Hla-binding oligopeptide and immunomodulating agent containing the compound

Non-Patent Citations (12)

* Cited by examiner, † Cited by third party
Title
GOLDSTEIN S. ET AL.: "Bioactive conformations of peptides and mimetics as milestones in drug design: Investigations of NK-1 antagonists", LETTERS IN PEPTIDE SCIENCE, vol. 2, no. 3-4, 1995, pages 125 - 134, XP000650996 *
KUHNS W.J. ET AL.: "Hyaluronic acid-receptor binding demonstrated by synthetic adhesive proteoglycan peptide constructs and by cell receptors on the matine sponge microciona prolifera", BIOLOGICAL BULLETIN, vol. 195, no. 2, October 1998 (1998-10-01), pages 216 - 218, XP002939503 *
LAMBKIN I. ET AL.: "Identification of peptide mimetics from phage display libraries which bind to recombinant forms of the human thromboxane A-2 receptor", JOURNAL OF CONTROLLED RELEASE, vol. 46, no. 1-2, September 1995 (1995-09-01), pages 190 - 191, XP004055755 *
MARTIN-MOE S.A. ET AL.: "Hydrophobic interactions and the design of receptor mimetic peptides", PEPTIDE RESEARCH, vol. 8, no. 2, March 1995 (1995-03-01) - April 1995 (1995-04-01), pages 70 - 76, XP002939505 *
PRICE K.N. ET AL.: "Synthetic and structural studies on glycosaminoglycan-type oligosaccharides and mimics", ABSTRACTS OF PAPERS, AMERICAN CHEMICAL SOCIETY, vol. 212, no. 1-2, August 1996 (1996-08-01), pages CARB, ABSTRACT NO. 013, XP002939504 *
ROQUES B.P.: "Peptidomimetics as receptors agonists or peptidase inhibitors: A structural approach in the field of enkephalins, ANP and CCK", BIOPOLYMERS, vol. 32, no. 4, April 1992 (1992-04-01), pages 407 - 410, XP002939508 *
See also references of EP1169048A4 *
SUCHANEK E. ET AL.: "Follicular fluid contents of hyaluronic acid, folliele-stimulating hormone and steroids relative to the success of in vitro fertilization of human oocytes", FERTILITY AND STERILITY, vol. 62, no. 2, August 1994 (1994-08-01), pages 347 - 352, XP002939511 *
TAUB M.E. ET AL.: "Influence of oligopeptide transporter binding affinity upon uptake and transport of D-Asp(OBzl)-ALa D-Asp(OBzl)-Sar in filter-grown Caco-2 monolayers", INTERNATIONAL JOURNAL OF PHARMACEUTICS, vol. 156, no. 2, 1997, pages 219 - 228, XP002939507 *
WISNIEWSKI H.G. ET AL.: "TSG-6, a glycoprotein associated with arthritis and its ligand hyaluronan exert opposite effects in a murine model in inflammations", PLUEGERS ARCH., vol. 431, no. 6, SUPPL. 2, 1996, pages R225 - R226, XP002939506 *
YE L. ET AL.: "Growth factor and cytokine-regulated hyaluronan-binding protein TSG-6 is localized to the injury-induced rat neointima and confers enhanced growth in vascular smooth muscle cells", CIRC. RES., vol. 81, no. 3, September 1997 (1997-09-01), pages 289 - 296, XP002939509 *
ZHANG L. ET AL.: "Hyaluronan on the surface of tumor cells is correlated with metastatic behavior", CANCER RESEARCH, vol. 55, no. 2, January 1995 (1995-01-01), pages 428 - 433, XP002939510 *

Also Published As

Publication number Publication date
WO2000001841A2 (en) 2000-01-13
EP1169048A2 (en) 2002-01-09
EP1169048A4 (en) 2002-07-17
AU4971699A (en) 2000-01-24
CA2346742A1 (en) 2000-01-13

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