ATE517926T1 - Antikörper zur hemmung der aktivität von mmp-2 und mmp-9 - Google Patents

Antikörper zur hemmung der aktivität von mmp-2 und mmp-9

Info

Publication number
ATE517926T1
ATE517926T1 AT04725641T AT04725641T ATE517926T1 AT E517926 T1 ATE517926 T1 AT E517926T1 AT 04725641 T AT04725641 T AT 04725641T AT 04725641 T AT04725641 T AT 04725641T AT E517926 T1 ATE517926 T1 AT E517926T1
Authority
AT
Austria
Prior art keywords
mmp
activity
antibodies
inhibit
antibody
Prior art date
Application number
AT04725641T
Other languages
English (en)
Inventor
Irit Sagi
Tamar Danon
Original Assignee
Yeda Res & Dev
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yeda Res & Dev filed Critical Yeda Res & Dev
Application granted granted Critical
Publication of ATE517926T1 publication Critical patent/ATE517926T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/44—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material not provided for elsewhere, e.g. haptens, metals, DNA, RNA, amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
AT04725641T 2003-04-04 2004-04-04 Antikörper zur hemmung der aktivität von mmp-2 und mmp-9 ATE517926T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US46000503P 2003-04-04 2003-04-04
PCT/IL2004/000308 WO2004087042A2 (en) 2003-04-04 2004-04-04 Antibodies and pharmaceutical compositions containing same useful for inhibiting activity of metalloproteins

Publications (1)

Publication Number Publication Date
ATE517926T1 true ATE517926T1 (de) 2011-08-15

Family

ID=33131910

Family Applications (1)

Application Number Title Priority Date Filing Date
AT04725641T ATE517926T1 (de) 2003-04-04 2004-04-04 Antikörper zur hemmung der aktivität von mmp-2 und mmp-9

Country Status (6)

Country Link
US (4) US7524938B2 (de)
EP (2) EP1610678B1 (de)
AT (1) ATE517926T1 (de)
DK (2) DK2330132T3 (de)
ES (2) ES2369498T3 (de)
WO (1) WO2004087042A2 (de)

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ES2369498T3 (es) 2003-04-04 2011-12-01 Yeda Research And Development Co., Ltd. Anticuerpos para inhibir la actividad de mmp-2 y mmp-9.
KR20070100968A (ko) * 2005-02-09 2007-10-15 제넨테크, 인크. 매트릭스 메탈로프로테아제 길항제를 사용한, ｈｅｒ2박리의 억제
WO2007079218A2 (en) 2005-12-30 2007-07-12 Dyax Corp. Metalloproteinase binding proteins
MX2009008914A (es) * 2007-02-23 2009-08-28 Yeda Res & Dev Anticuerpos y composiciones farmaceuticas que contienen los mismos, utiles para inhibir la actividad de metaloproteinas.
US8536313B2 (en) 2007-07-10 2013-09-17 Shionogi & Co., Ltd. Monoclonal antibody having neutralizing activity against MMP13
MX2010001657A (es) * 2007-08-15 2010-03-15 Yeda Res & Dev Reguladores de mmp-9 y usos de los mismos.
US8183008B2 (en) * 2007-12-17 2012-05-22 Dyax Corp. Evaluating MMP expression in patient stratification and other therapeutic, diagnostic and prognostic methods for cancer
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WO2010029352A1 (en) * 2008-09-09 2010-03-18 University Of East Anglia Treatment of fibrotic eye disorders using an mmp2 inhibitor
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EP2528949A1 (de) 2010-01-27 2012-12-05 Yeda Research And Development Co. Ltd. Antikörper zur hemmung von metalloproteinen
KR101518144B1 (ko) 2010-08-27 2015-05-28 길리아드 바이오로직스, 인크. 매트릭스 메탈로프로테이나제 ９에 대한 항체
WO2012056455A1 (en) 2010-10-28 2012-05-03 Yeda Research And Development Co. Ltd. Methods of generating antibodies to metalloenzymes
US10314909B2 (en) 2011-10-21 2019-06-11 Dyax Corp. Combination therapy comprising an MMP-14 binding protein
CA2861402C (en) * 2012-01-30 2021-10-12 Guy Casy Stabilized aqueous antibody compositions
SG10201610788VA (en) * 2012-02-29 2017-03-30 Gilead Biologics Inc Antibodies to matrix metalloproteinase 9
JP7109440B2 (ja) 2017-07-18 2022-07-29 第一三共株式会社 活性型ｍｍｐ－９結合ペプチド
IL264768A (en) 2019-02-10 2020-08-31 Sagi Irit ANTI-MATRIX METALLOPROTEINASE 7 (MMP-7) inhibitory antibody and its use

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Also Published As

Publication number Publication date
DK1610678T3 (da) 2011-10-24
EP1610678A4 (de) 2008-04-09
EP2330132A1 (de) 2011-06-08
WO2004087042A2 (en) 2004-10-14
US20140370031A1 (en) 2014-12-18
ES2369498T3 (es) 2011-12-01
US20090208510A1 (en) 2009-08-20
US20120003236A1 (en) 2012-01-05
EP1610678B1 (de) 2011-07-27
WO2004087042A3 (en) 2005-07-14
US7524938B2 (en) 2009-04-28
US20070172482A1 (en) 2007-07-26
DK2330132T3 (da) 2013-11-04
ES2433440T3 (es) 2013-12-11
US8841108B2 (en) 2014-09-23
EP2330132B1 (de) 2013-08-14
EP1610678A2 (de) 2006-01-04

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