ATE505463T1 - Benzodiazepin-derivate, verwendbar als cck- rezeptor antagonisten - Google Patents
Benzodiazepin-derivate, verwendbar als cck- rezeptor antagonistenInfo
- Publication number
- ATE505463T1 ATE505463T1 AT03010776T AT03010776T ATE505463T1 AT E505463 T1 ATE505463 T1 AT E505463T1 AT 03010776 T AT03010776 T AT 03010776T AT 03010776 T AT03010776 T AT 03010776T AT E505463 T1 ATE505463 T1 AT E505463T1
- Authority
- AT
- Austria
- Prior art keywords
- alkyl
- groups
- receptor antagonists
- atoms
- benzodiazepine derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
- C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
- C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
- C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
- C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
- C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
- C07D243/24—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB9204221A GB2264492B (en) | 1992-02-27 | 1992-02-27 | Benzodiazepine derivatives |
GB929212740A GB9212740D0 (en) | 1992-02-27 | 1992-06-16 | Benzodiazephine derivatives |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE505463T1 true ATE505463T1 (de) | 2011-04-15 |
Family
ID=10711162
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT03010776T ATE505463T1 (de) | 1992-02-27 | 1993-02-26 | Benzodiazepin-derivate, verwendbar als cck- rezeptor antagonisten |
Country Status (7)
Country | Link |
---|---|
EP (1) | EP1342719B1 (de) |
KR (1) | KR100282587B1 (de) |
AT (1) | ATE505463T1 (de) |
DE (1) | DE69334353D1 (de) |
ES (1) | ES2364637T3 (de) |
GB (2) | GB2264492B (de) |
ZA (1) | ZA931381B (de) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9315494D0 (en) * | 1993-07-27 | 1993-09-08 | Springer Caroline | Improvements relating to prodrugs |
GB2282594A (en) * | 1993-08-25 | 1995-04-12 | Yamanouchi Pharma Co Ltd | Benzodiazepine derivatives |
GB2282595A (en) * | 1993-08-25 | 1995-04-12 | Yamanouchi Pharma Co Ltd | Benzodiazepine derivatives |
GB201414116D0 (en) * | 2014-08-08 | 2014-09-24 | Trio Medicines Ltd | Benzodiazepine derivatives |
GB201513979D0 (en) * | 2015-08-07 | 2015-09-23 | Trio Medicines Ltd | Synthesis of benzodiazepine derivatives |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4820834A (en) | 1984-06-26 | 1989-04-11 | Merck & Co., Inc. | Benzodiazepine analogs |
CA2026856A1 (en) * | 1989-10-05 | 1991-04-06 | Mark G. Bock | 3-substituted-1,4-benzodiazepines useful as oxytocin |
CA2032427A1 (en) * | 1989-12-18 | 1991-06-19 | Mark G. Bock | Benzodiazepines analogs |
CA2032226A1 (en) * | 1989-12-18 | 1991-06-19 | Mark G. Bock | Benzodiazepine analogs |
IL96613A0 (en) * | 1989-12-18 | 1991-09-16 | Merck & Co Inc | Pharmaceutical compositions containing benzodiazepine analogs |
US4994258A (en) | 1990-03-05 | 1991-02-19 | Merck & Co., Inc. | Gamma emitting, CCK-A antagonists for pancreatic imaging |
US5218115A (en) * | 1991-04-10 | 1993-06-08 | Merck & Co., Inc. | Cholecystokinin antagonists |
US5218114A (en) * | 1991-04-10 | 1993-06-08 | Merck & Co., Inc. | Cholecystokinin antagonists |
FR2682381B1 (fr) * | 1991-10-10 | 1995-04-07 | Rhone Poulenc Rorer Sa | Derives de benzodiazepine, leur preparation et les medicaments les contenant. |
WO1993008175A1 (en) * | 1991-10-24 | 1993-04-29 | Glaxo Group Limited | Benzodiazepine derivatives as antagonists of gastrin and/or cholecystokinin |
-
1992
- 1992-02-27 GB GB9204221A patent/GB2264492B/en not_active Revoked
- 1992-06-16 GB GB929212740A patent/GB9212740D0/en active Pending
-
1993
- 1993-02-26 EP EP03010776A patent/EP1342719B1/de not_active Expired - Lifetime
- 1993-02-26 DE DE69334353T patent/DE69334353D1/de not_active Expired - Lifetime
- 1993-02-26 KR KR1019940702875A patent/KR100282587B1/ko not_active IP Right Cessation
- 1993-02-26 ZA ZA931381A patent/ZA931381B/xx unknown
- 1993-02-26 ES ES03010776T patent/ES2364637T3/es not_active Expired - Lifetime
- 1993-02-26 AT AT03010776T patent/ATE505463T1/de not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
EP1342719A1 (de) | 2003-09-10 |
DE69334353D1 (de) | 2011-05-26 |
GB9204221D0 (en) | 1992-04-08 |
ES2364637T3 (es) | 2011-09-08 |
EP1342719B1 (de) | 2011-04-13 |
KR100282587B1 (ko) | 2001-02-15 |
ZA931381B (en) | 1993-12-15 |
GB2264492A (en) | 1993-09-01 |
GB2264492B (en) | 1996-09-25 |
GB2264492A8 (de) | 1996-07-29 |
GB9212740D0 (en) | 1992-07-29 |
KR950700225A (ko) | 1995-01-16 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |