ATE499384T1 - Multimere fc-rezeptor-polypeptide - Google Patents

Multimere fc-rezeptor-polypeptide

Info

Publication number
ATE499384T1
ATE499384T1 AT06828004T AT06828004T ATE499384T1 AT E499384 T1 ATE499384 T1 AT E499384T1 AT 06828004 T AT06828004 T AT 06828004T AT 06828004 T AT06828004 T AT 06828004T AT E499384 T1 ATE499384 T1 AT E499384T1
Authority
AT
Austria
Prior art keywords
protein
polypeptide
multimer
receptor polypeptides
riia
Prior art date
Application number
AT06828004T
Other languages
English (en)
Inventor
Phillip Hogarth
Bruce Wines
Original Assignee
Suppremol Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Suppremol Gmbh filed Critical Suppremol Gmbh
Application granted granted Critical
Publication of ATE499384T1 publication Critical patent/ATE499384T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/70535—Fc-receptors, e.g. CD16, CD32, CD64 (CD2314/705F)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/52—Constant or Fc region; Isotype
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/32—Fusion polypeptide fusions with soluble part of a cell surface receptor, "decoy receptors"

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Transplantation (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT06828004T 2005-12-13 2006-12-13 Multimere fc-rezeptor-polypeptide ATE499384T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US75030105P 2005-12-13 2005-12-13
PCT/AU2006/001890 WO2007068047A1 (en) 2005-12-13 2006-12-13 Multimeric fc receptor polypeptides

Publications (1)

Publication Number Publication Date
ATE499384T1 true ATE499384T1 (de) 2011-03-15

Family

ID=38162476

Family Applications (1)

Application Number Title Priority Date Filing Date
AT06828004T ATE499384T1 (de) 2005-12-13 2006-12-13 Multimere fc-rezeptor-polypeptide

Country Status (7)

Country Link
EP (1) EP1960427B1 (de)
AT (1) ATE499384T1 (de)
DE (1) DE602006020333D1 (de)
ES (1) ES2359218T3 (de)
PL (1) PL1960427T3 (de)
PT (1) PT1960427E (de)
WO (1) WO2007068047A1 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1730170B1 (de) 2004-03-10 2020-02-19 Trinity Therapeutics, Inc. Verfahren zur inhibierung der immunkomplexbildung in einem probanden
CA2671732A1 (en) * 2006-12-13 2008-06-19 Suppremol Gmbh Multimeric fc receptor polypeptides including a modified fc domain
WO2009023777A2 (en) * 2007-08-14 2009-02-19 Trinity Therapeutics, Inc. Methods for treating immune thrombocytopenia
MY160699A (en) 2008-07-18 2017-03-15 Trinity Therapeutics Inc Methods for treating immune-mediated dengue fever infections and antibody-dependent enhancement of dengue fever infections, including dengue hemorrhagic fever and dengue shock syndrome
US10669324B2 (en) 2012-10-30 2020-06-02 Suppremol Gmbh Vector encoding an Fc gamma receptor IIB protein and composition of the encoded protein
US10028998B2 (en) 2012-10-30 2018-07-24 Suppremol Gmbh Method for treating an inflammatory disease and/or an autoimmune disease with a soluble FcγRIIb
AU2012244302B2 (en) * 2012-10-31 2014-08-21 Suppremol Gmbh A method for treating or preventing either one or both of an inflammatory disease and an autoimmune disease
EP2796144A1 (de) 2013-04-26 2014-10-29 SuppreMol GmbH Hochkonzentrierte Formulierungen von löslichen Fc-Rezeptoren
EP2837637A1 (de) 2013-08-16 2015-02-18 SuppreMol GmbH Neuartiger FcyRIIB IgG-Antikörper

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1991006570A1 (en) * 1989-10-25 1991-05-16 The University Of Melbourne HYBRID Fc RECEPTOR MOLECULES
CA2512974A1 (en) 2003-01-13 2004-07-29 Macrogenics, Inc. Soluble fc.gamma.r fusion proteins and methods of use thereof

Also Published As

Publication number Publication date
WO2007068047A1 (en) 2007-06-21
ES2359218T3 (es) 2011-05-19
PT1960427E (pt) 2011-03-22
PL1960427T3 (pl) 2011-07-29
EP1960427A4 (de) 2009-03-04
DE602006020333D1 (de) 2011-04-07
EP1960427B1 (de) 2011-02-23
EP1960427A1 (de) 2008-08-27

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