ATE499107T1 - Manipulation der rate des gastrointestinalen transits durch modulation der methankonzentration im darm - Google Patents
Manipulation der rate des gastrointestinalen transits durch modulation der methankonzentration im darmInfo
- Publication number
- ATE499107T1 ATE499107T1 AT03741819T AT03741819T ATE499107T1 AT E499107 T1 ATE499107 T1 AT E499107T1 AT 03741819 T AT03741819 T AT 03741819T AT 03741819 T AT03741819 T AT 03741819T AT E499107 T1 ATE499107 T1 AT E499107T1
- Authority
- AT
- Austria
- Prior art keywords
- rate
- intestinal
- manipulation
- modulation
- gastrointestinal transit
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
- A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
- A61K31/7036—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin having at least one amino group directly attached to the carbocyclic ring, e.g. streptomycin, gentamycin, amikacin, validamycin, fortimicins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/01—Hydrocarbons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/351—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom not condensed with another ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
- A61K31/405—Indole-alkanecarboxylic acids; Derivatives thereof, e.g. tryptophan, indomethacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/74—Synthetic polymeric materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/74—Bacteria
- A61K35/741—Probiotics
- A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
- A61K35/745—Bifidobacteria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/74—Bacteria
- A61K35/741—Probiotics
- A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
- A61K35/747—Lactobacilli, e.g. L. acidophilus or L. brevis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/06—Fungi, e.g. yeasts
- A61K36/062—Ascomycota
- A61K36/064—Saccharomycetales, e.g. baker's yeast
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/10—Laxatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/12—Antidiarrhoeals
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Biochemistry (AREA)
- Virology (AREA)
- Biomedical Technology (AREA)
- Medical Informatics (AREA)
- Botany (AREA)
- Alternative & Traditional Medicine (AREA)
- Tropical Medicine & Parasitology (AREA)
- General Engineering & Computer Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Plant Substances (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US38217202P | 2002-05-20 | 2002-05-20 | |
PCT/US2003/016656 WO2003100023A2 (en) | 2002-05-20 | 2003-05-20 | Manipulation of the rate of gastrointestinal transit by modulating intestinal methane concentration |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE499107T1 true ATE499107T1 (de) | 2011-03-15 |
Family
ID=29584369
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT03741819T ATE499107T1 (de) | 2002-05-20 | 2003-05-20 | Manipulation der rate des gastrointestinalen transits durch modulation der methankonzentration im darm |
Country Status (10)
Country | Link |
---|---|
US (4) | US20060246045A1 (de) |
EP (2) | EP1505989B1 (de) |
JP (1) | JP2005526861A (de) |
AT (1) | ATE499107T1 (de) |
AU (1) | AU2003273141B2 (de) |
CA (2) | CA2486585C (de) |
DE (1) | DE60336128D1 (de) |
ES (3) | ES2361007T3 (de) |
PT (1) | PT1505989E (de) |
WO (1) | WO2003100023A2 (de) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2361007T3 (es) | 2002-05-20 | 2011-06-13 | Cedars-Sinai Medical Center | Manipulación de la tasa de tránsito gastrointestinal al modular la concentración de metano intestinal. |
US10066254B2 (en) | 2002-05-20 | 2018-09-04 | Cedars-Sinai Medical Center | Diagnosis of constipation by analysis of methane concentration |
FR2957754B1 (fr) * | 2010-03-26 | 2012-04-27 | Inst Nat De La Rech Agronomique Inra | Utilisation d'un produit de fermentation fongique comme complement alimentaire |
FR2971123B1 (fr) * | 2011-02-08 | 2013-11-22 | Solvay | Galactofructose pour son effet regulateur du transit intestinal |
US9289418B2 (en) | 2013-03-15 | 2016-03-22 | Cedars-Sinai Medical Center | Methods of diagnosis, selection, and treatment of diseases and conditions caused by or associated with methanogens |
US9744208B2 (en) * | 2013-03-15 | 2017-08-29 | Cedars-Sinai Medical Center | Methods of diagnosis, selection, and treatment of diseases and conditions caused by or associated with methanogens |
CN106687107B (zh) | 2014-08-13 | 2020-12-25 | 西达-赛奈医疗中心 | 抗产甲烷组合物及其用途 |
KR101611212B1 (ko) | 2014-11-19 | 2016-04-12 | 한국생명공학연구원 | 메탄균 생육저해 미생물 및 그 용도 |
MX2017011549A (es) * | 2015-03-16 | 2017-10-26 | Ecole Polytechnique Fed De Lausanne (Epfl) | Archaebacteria en alimento para animales bioactivo, metodo para hacer la composicion y metodos que emplean la composicion. |
WO2016161085A1 (en) | 2015-04-01 | 2016-10-06 | Cedars-Sinai Medical Center | Anti-methanogenic lovastatin analogs or derivatives and uses thereof |
AU2016315721B2 (en) * | 2015-09-02 | 2022-04-07 | Cedars-Sinai Medical Center | Breath gas analysis |
JP2021528475A (ja) | 2018-06-27 | 2021-10-21 | − ブルース サザーランド、ダンカン | 死滅したまたは不活化されたメタノブレビバクター古細菌(Methanobrevibacter Archaebacteria)細胞を含む組成物を調製するための方法およびそれによって得られる組成物 |
CN111671791A (zh) * | 2020-05-25 | 2020-09-18 | 中山大学 | 一种靶向肠道菌群改善便秘的微生态组合物及其制剂 |
JP2023553202A (ja) | 2020-12-08 | 2023-12-20 | ルミナント バイオテク コーポレーション リミテッド | 動物に物質を送達するための装置および方法の改善 |
Family Cites Families (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB423083A (en) * | 1934-05-22 | 1935-01-24 | Hugh Edwin Johnstone Peake | Improvements in and relating to the manufacture of fermented beverages and medicinalpreparations |
JPS60133852A (ja) * | 1983-12-23 | 1985-07-17 | Zenkoku Shokubutsu Tanpaku Shokuhin Kyodo Kumiai | 新規な納豆製品 |
DE3718638A1 (de) * | 1987-06-04 | 1988-12-22 | Thomae Gmbh Dr K | Neue phenylethanolamine, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung |
JPH03275630A (ja) * | 1990-03-23 | 1991-12-06 | Hayashikane Sangyo Kk | 肝機能改善剤及び肝機能改善食品又は飲料 |
PT724454E (pt) * | 1993-10-19 | 2004-08-31 | Commw Scient Ind Res Org | Metodo para melhorar a utilizacao de nutrientes pelos animais ruminantes ou semelhantes a ruminantes |
US5447850A (en) * | 1994-01-31 | 1995-09-05 | Mccann; James L. | Method of producing methane from organic waste |
US6861053B1 (en) * | 1999-08-11 | 2005-03-01 | Cedars-Sinai Medical Center | Methods of diagnosing or treating irritable bowel syndrome and other disorders caused by small intestinal bacterial overgrowth |
US6562629B1 (en) * | 1999-08-11 | 2003-05-13 | Cedars-Sinai Medical Center | Method of diagnosing irritable bowel syndrome and other disorders caused by small intestinal bacterial overgrowth by detecting the presence of anti-saccharomyces cerivisiae antibodies (asca) in human serum |
EP0827402A2 (de) | 1995-05-17 | 1998-03-11 | Cedars-Sinai Medical Center | Fettsäure enthaltende zusammensetzungen zur verbesserung der verdauung und absorption des dünndarms |
US7048906B2 (en) * | 1995-05-17 | 2006-05-23 | Cedars-Sinai Medical Center | Methods of diagnosing and treating small intestinal bacterial overgrowth (SIBO) and SIBO-related conditions |
US6558708B1 (en) * | 1995-05-17 | 2003-05-06 | Cedars-Sinai Medical Center | Methods for manipulating upper gastrointestinal transit, blood flow, and satiety, and for treating visceral hyperalgesia |
JP3010007B2 (ja) * | 1995-05-22 | 2000-02-14 | ビオフェルミン製薬株式会社 | 配合下剤 |
US5889038A (en) * | 1996-03-20 | 1999-03-30 | Children's Hospital | Methods and products for treating diarrhea and scours: use of clotrimazole and related aromatic compounds |
CN1119154C (zh) * | 1998-01-20 | 2003-08-27 | 上海信谊药业有限公司 | 双歧三联活菌制剂及制备方法 |
US6368591B2 (en) * | 1998-05-15 | 2002-04-09 | Shanghai Sine Pharmaceutical Corporation Ltd. | Beneficial microbe composition, new protective materials for the microbes, method to prepare the same and uses thereof |
US5985907A (en) | 1998-08-12 | 1999-11-16 | Health Research, Inc. | Method for inhibiting growth of methanogens |
US6328959B1 (en) * | 1998-09-18 | 2001-12-11 | The United States Of America As Represented By The Secretary Of The Navy | Intestinal hydrogen removal using hydrogen-metabolizing microbes |
DE60122881T2 (de) * | 2000-06-13 | 2007-01-11 | Unilever N.V. | Nicht-lebensfähigen lactobacillus enthaltendes lebensmittelprodukt |
US6299774B1 (en) * | 2000-06-26 | 2001-10-09 | Jack L. Ainsworth | Anaerobic digester system |
ES2361007T3 (es) | 2002-05-20 | 2011-06-13 | Cedars-Sinai Medical Center | Manipulación de la tasa de tránsito gastrointestinal al modular la concentración de metano intestinal. |
US10066254B2 (en) | 2002-05-20 | 2018-09-04 | Cedars-Sinai Medical Center | Diagnosis of constipation by analysis of methane concentration |
ITBO20020564A1 (it) * | 2002-09-06 | 2004-03-07 | Alfa Wassermann Spa | Bifidobatteri e preparazioni che li contengono. |
-
2003
- 2003-05-20 ES ES03741819T patent/ES2361007T3/es not_active Expired - Lifetime
- 2003-05-20 AT AT03741819T patent/ATE499107T1/de not_active IP Right Cessation
- 2003-05-20 EP EP20030741819 patent/EP1505989B1/de not_active Expired - Lifetime
- 2003-05-20 US US10/514,188 patent/US20060246045A1/en not_active Abandoned
- 2003-05-20 ES ES10173966.2T patent/ES2535489T3/es not_active Expired - Lifetime
- 2003-05-20 AU AU2003273141A patent/AU2003273141B2/en not_active Ceased
- 2003-05-20 EP EP20100173966 patent/EP2251017B1/de not_active Expired - Lifetime
- 2003-05-20 JP JP2004508265A patent/JP2005526861A/ja active Pending
- 2003-05-20 WO PCT/US2003/016656 patent/WO2003100023A2/en active Application Filing
- 2003-05-20 CA CA 2486585 patent/CA2486585C/en not_active Expired - Fee Related
- 2003-05-20 DE DE60336128T patent/DE60336128D1/de not_active Expired - Lifetime
- 2003-05-20 PT PT03741819T patent/PT1505989E/pt unknown
- 2003-05-20 CA CA2771788A patent/CA2771788C/en not_active Expired - Lifetime
- 2003-10-20 ES ES03751150T patent/ES2361008T3/es not_active Expired - Lifetime
-
2008
- 2008-02-13 US US12/030,758 patent/US9066962B2/en active Active
-
2014
- 2014-04-16 US US14/254,483 patent/US9358245B2/en not_active Expired - Lifetime
- 2014-12-09 US US14/565,239 patent/US9192618B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
AU2003273141B2 (en) | 2009-05-07 |
US9066962B2 (en) | 2015-06-30 |
ES2361007T3 (es) | 2011-06-13 |
US20140228431A1 (en) | 2014-08-14 |
ES2361008T3 (es) | 2011-06-13 |
WO2003100023A2 (en) | 2003-12-04 |
CA2486585A1 (en) | 2003-12-04 |
EP2251017B1 (de) | 2015-03-25 |
WO2003100023A3 (en) | 2004-04-08 |
JP2005526861A (ja) | 2005-09-08 |
CA2771788A1 (en) | 2003-12-04 |
US20150099713A1 (en) | 2015-04-09 |
US9358245B2 (en) | 2016-06-07 |
EP1505989A2 (de) | 2005-02-16 |
EP1505989B1 (de) | 2011-02-23 |
EP2251017A1 (de) | 2010-11-17 |
ES2535489T3 (es) | 2015-05-12 |
EP1505989A4 (de) | 2007-05-09 |
US9192618B2 (en) | 2015-11-24 |
PT1505989E (pt) | 2011-03-29 |
US20080138320A1 (en) | 2008-06-12 |
DE60336128D1 (de) | 2011-04-07 |
CA2486585C (en) | 2012-07-10 |
CA2771788C (en) | 2022-03-22 |
AU2003273141A1 (en) | 2003-12-12 |
US20060246045A1 (en) | 2006-11-02 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |