ATE49592T1 - 6-sauerstoffhaltige-1,3,4,5tetrahydrobenz(cd)indole-4-amine. - Google Patents

6-sauerstoffhaltige-1,3,4,5tetrahydrobenz(cd)indole-4-amine.

Info

Publication number: ATE49592T1
Authority: AT; Austria
Prior art keywords: oxygenated; indole; amines; alkyl; hydrogen
Prior art date: 1984-05-24

Application number

AT85303556T

Other languages

English (en)

Inventor

Carl Kaiser

Lawrence Ivan Kruse

Original Assignee

Smithkline Beckman Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1984-05-24

Filing date

1985-05-21

Publication date

1990-02-15

1985-05-21 Application filed by Smithkline Beckman Corp filed Critical Smithkline Beckman Corp

1990-02-15 Application granted granted Critical

1990-02-15 Publication of ATE49592T1 publication Critical patent/ATE49592T1/de

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, ***e
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/56—Ring systems containing three or more rings
- C07D209/80—[b, c]- or [b, d]-condensed
- C07D209/90—Benzo [c, d] indoles; Hydrogenated benzo [c, d] indoles

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Engineering & Computer Science (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
Psychiatry (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Pain & Pain Management (AREA)
Indole Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

AT85303556T 1984-05-24 1985-05-21 6-sauerstoffhaltige-1,3,4,5tetrahydrobenz(cd)indole-4-amine. ATE49592T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US61383984A	1984-05-24	1984-05-24
EP85303556A EP0162695B1 (de)	1984-05-24	1985-05-21	6-Sauerstoffhaltige-1,3,4,5-Tetrahydrobenz(cd)indole-4-amine

Publications (1)

Publication Number	Publication Date
ATE49592T1 true ATE49592T1 (de)	1990-02-15

Family

ID=24458880

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT85303556T ATE49592T1 (de)	1984-05-24	1985-05-21	6-sauerstoffhaltige-1,3,4,5tetrahydrobenz(cd)indole-4-amine.

Country Status (11)

Country	Link
EP (1)	EP0162695B1 (de)
JP (1)	JPS60258162A (de)
AT (1)	ATE49592T1 (de)
AU (1)	AU581000B2 (de)
CA (1)	CA1266482A1 (de)
DE (1)	DE3575420D1 (de)
DK (1)	DK222385A (de)
ES (2)	ES8700233A1 (de)
GR (1)	GR851263B (de)
PT (1)	PT80524B (de)
ZA (1)	ZA853913B (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3346573A1 (de) *	1983-12-23	1985-07-04	Troponwerke GmbH & Co KG, 5000 Köln	1,3,4,5-tetrahydrobenz(c,d)indole, ein verfahren zu ihrer herstellung und ihre verwendung
IL74222A (en) *	1984-02-06	1988-07-31	Lilly Co Eli	6-substituted-4-dialkylamino tetrahydrobenz(c,d)indoles,their preparation and pharmaceutical compositions comprising them
US4983622A (en) *	1984-02-06	1991-01-08	Eli Lilly And Company	6-substituted-4-dialkylaminotetrahydrobenz(c,d)indoles
US5026869A (en) *	1984-02-06	1991-06-25	Eli Lilly And Company	6-substituted-4-dialkylaminotetrahydrobenz(c,d)indoles
DE3718892A1 (de) *	1987-06-05	1988-12-22	Bayer Ag	Polyhydrobenz(c,d)indol-sulfonamide
DE3809155A1 (de) *	1988-03-18	1989-09-28	Bayer Ag	1,3,4,5-tetrahydrobenz-(c,d)-indole
US5204340A (en) *	1989-04-11	1993-04-20	Eli Lilly And Company	Tetrahydrobenz(c,d)indole serotonin agonists
US5302612A (en) *	1990-02-26	1994-04-12	Eli Lilly And Company	6-substituted-hexahydrobenz[cd]indoles
US5229410A (en) *	1990-08-15	1993-07-20	Eli Lilly And Company	6-substituted-hexahydrobenz[cd]indoles
US5229409A (en) *	1990-08-15	1993-07-20	Eli Lilly And Company	6-substituted-tetrahydrobenz[cd]indoles
US5244912A (en) *	1991-03-28	1993-09-14	Eli Lilly And Company	6-heterocyclic-4-amino-1,3,4,5-tetrahydrobenz(cd)indoles and pharmaceutical use thereof
US5244911A (en) *	1991-03-28	1993-09-14	Eli Lilly And Company	6-heterocyclic-4-amino-1,2,2a,3,4,5-hexahydrobenz(cd)indoles and pharmaceutical use thereof
US5656653A (en) *	1991-03-28	1997-08-12	Eli Lilly And Company	6-heterocyclic-4-amino-1,2,2A,3,4,5-hexahydrobenz[cd]indoles
US5347013A (en) *	1991-03-28	1994-09-13	Eli Lilly And Company	6-heterocyclic-4-amino-1,2,2a,3,4,5-hexahydrobenz[cd]indoles
US5364856A (en) *	1991-03-28	1994-11-15	Eli Lilly And Company	6-heterocyclic-4-amino-1,3,4,5-tetrahydrobenz[CD]indoles
CZ285762B6 (cs) *	1993-06-10	1999-11-17	Eli Lilly And Company	Farmaceutický prostředek vhodný pro prevenci dávení a zvracení a pro ošetřování sexuální dysfunkce savců a jeho použití
FR2732964B1 (fr) *	1995-04-14	1997-05-16	Adir	Nouveaux amides tricycliques, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3194811A (en) *	1963-09-05	1965-07-13	Merck & Co Inc	Aroyl-benzindolyl acids
CH517732A (de) *	1969-10-24	1972-01-15	Sandoz Ag	Verfahren zur Herstellung neuer Guanidin- Verbindungen
US4110339A (en) *	1977-11-25	1978-08-29	Eli Lilly And Company	4-(Di-n-propyl)amino-1,3,4,5-tetrahydrobenz[cd]indole
US4282240A (en) *	1979-11-23	1981-08-04	Merck & Co., Inc.	Amino substituted tetrahydrobenzindoles
DE3346573A1 (de) *	1983-12-23	1985-07-04	Troponwerke GmbH & Co KG, 5000 Köln	1,3,4,5-tetrahydrobenz(c,d)indole, ein verfahren zu ihrer herstellung und ihre verwendung
IL74222A (en) *	1984-02-06	1988-07-31	Lilly Co Eli	6-substituted-4-dialkylamino tetrahydrobenz(c,d)indoles,their preparation and pharmaceutical compositions comprising them

1985
- 1985-04-09 CA CA000478535A patent/CA1266482A1/en active Granted
- 1985-05-20 DK DK222385A patent/DK222385A/da not_active Application Discontinuation
- 1985-05-21 EP EP85303556A patent/EP0162695B1/de not_active Expired - Lifetime
- 1985-05-21 DE DE8585303556T patent/DE3575420D1/de not_active Expired - Fee Related
- 1985-05-21 AT AT85303556T patent/ATE49592T1/de active
- 1985-05-22 GR GR851263A patent/GR851263B/el unknown
- 1985-05-23 ZA ZA853913A patent/ZA853913B/xx unknown
- 1985-05-23 PT PT80524A patent/PT80524B/pt not_active IP Right Cessation
- 1985-05-23 ES ES543421A patent/ES8700233A1/es not_active Expired
- 1985-05-23 AU AU42796/85A patent/AU581000B2/en not_active Ceased
- 1985-05-23 JP JP60111986A patent/JPS60258162A/ja active Pending
1986
- 1986-02-13 ES ES551944A patent/ES8706117A1/es not_active Expired

Also Published As

Publication number	Publication date
ES551944A0 (es)	1987-06-01
PT80524A (en)	1985-06-01
ES8706117A1 (es)	1987-06-01
GR851263B (de)	1985-11-25
AU581000B2 (en)	1989-02-09
EP0162695B1 (de)	1990-01-17
JPS60258162A (ja)	1985-12-20
DE3575420D1 (de)	1990-02-22
PT80524B (en)	1987-04-06
ES543421A0 (es)	1986-09-16
CA1266675C (de)	1990-03-13
CA1266482A1 (en)	1990-03-06
DK222385A (da)	1985-11-25
EP0162695A1 (de)	1985-11-27
AU4279685A (en)	1985-11-28
ES8700233A1 (es)	1986-09-16
DK222385D0 (da)	1985-05-20
ZA853913B (en)	1986-01-29

Publication	Publication Date	Title
ATE49592T1 (de)	1990-02-15	6-sauerstoffhaltige-1,3,4,5tetrahydrobenz(cd)indole-4-amine.
DE69021679T2 (de)	1996-01-25	Verwendung von Bis(3,4-Dialkylbenzyliden)sorbitolacetale und diese enthaltende Zusammensetzungen.
DK58292D0 (da)	1992-05-04	Som mellemprodukter anvendelige 4(5)-imidazolderivater
PT88603A (pt)	1988-10-01	Immunomodulatory azapiranes
FI844333A0 (fi)	1984-11-05	11-substituerade 5h,11h-pyrrolo/2,1-c/ /1,4/benzoxazepiner, foerfarande foer deras framstaellning och deras anvaendning som laekemedel.
DE3362504D1 (en)	1986-04-17	1-carboxyalkanoylindoline-2-carboxylic-acid esters, their preparation, pharmaceutical compositions containing them, and their therapeutic use
FI862420A0 (fi)	1986-06-06	Pyrrolidonderivat.
SE8303913D0 (sv)	1983-07-08	Heterocykliska foreningar
IL70341A0 (en)	1984-02-29	Pyrimidone derivatives,processes for their preparation,pharmaceutical compositions containing them and their use as histamine antagonists
SE8506125D0 (sv)	1985-12-23	8alfa-acylaminoergolines, their production and pharmaceutical compositions containing them
FI872997A0 (fi)	1987-07-07	Amidderivat.
ATE38029T1 (de)	1988-11-15	Benz-trisubstituierte 2-aminotetraline.
FI873145A0 (fi)	1987-07-16	Nya tetracykliska indolderivat.
ES2044883T3 (es)	1994-01-16	Procedimiento para preparar quinoxalinas sustituidas.
ATE74604T1 (de)	1992-04-15	Substituierte pyrimidochinoxaline.