ATE494907T1 - Pharmazeutische zusammensetzungen, die immunologisch aktive herpes simplex virus proteinfragmente enthalten - Google Patents
Pharmazeutische zusammensetzungen, die immunologisch aktive herpes simplex virus proteinfragmente enthaltenInfo
- Publication number
- ATE494907T1 ATE494907T1 AT08166335T AT08166335T ATE494907T1 AT E494907 T1 ATE494907 T1 AT E494907T1 AT 08166335 T AT08166335 T AT 08166335T AT 08166335 T AT08166335 T AT 08166335T AT E494907 T1 ATE494907 T1 AT E494907T1
- Authority
- AT
- Austria
- Prior art keywords
- antigens
- hsv
- compositions containing
- immunologically active
- pharmaceutical compositions
- Prior art date
Links
- 241000700584 Simplexvirus Species 0.000 title 1
- 239000012634 fragment Substances 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 102000004169 proteins and genes Human genes 0.000 title 1
- 108090000623 proteins and genes Proteins 0.000 title 1
- 239000000427 antigen Substances 0.000 abstract 6
- 102000036639 antigens Human genes 0.000 abstract 6
- 108091007433 antigens Proteins 0.000 abstract 6
- 210000001744 T-lymphocyte Anatomy 0.000 abstract 3
- 238000000034 method Methods 0.000 abstract 3
- 208000009889 Herpes Simplex Diseases 0.000 abstract 2
- 241000700605 Viruses Species 0.000 abstract 2
- 210000004027 cell Anatomy 0.000 abstract 2
- 230000002265 prevention Effects 0.000 abstract 2
- 230000000840 anti-viral effect Effects 0.000 abstract 1
- 230000001472 cytotoxic effect Effects 0.000 abstract 1
- 230000002163 immunogen Effects 0.000 abstract 1
- 210000004698 lymphocyte Anatomy 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 102000040430 polynucleotide Human genes 0.000 abstract 1
- 108091033319 polynucleotide Proteins 0.000 abstract 1
- 239000002157 polynucleotide Substances 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 230000000069 prophylactic effect Effects 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
- 229960005486 vaccine Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/245—Herpetoviridae, e.g. herpes simplex virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/46—Cellular immunotherapy
- A61K39/461—Cellular immunotherapy characterised by the cell type used
- A61K39/4611—T-cells, e.g. tumor infiltrating lymphocytes [TIL], lymphokine-activated killer cells [LAK] or regulatory T cells [Treg]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/46—Cellular immunotherapy
- A61K39/464—Cellular immunotherapy characterised by the antigen targeted or presented
- A61K39/464838—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/515—Animal cells
- A61K2039/5158—Antigen-pulsed cells, e.g. T-cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5256—Virus expressing foreign proteins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
- C12N2710/16611—Simplexvirus, e.g. human herpesvirus 1, 2
- C12N2710/16622—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
- C12N2710/16611—Simplexvirus, e.g. human herpesvirus 1, 2
- C12N2710/16634—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/24011—Poxviridae
- C12N2710/24111—Orthopoxvirus, e.g. vaccinia virus, variola
- C12N2710/24141—Use of virus, viral particle or viral elements as a vector
- C12N2710/24143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US39679102P | 2002-07-18 | 2002-07-18 |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE494907T1 true ATE494907T1 (de) | 2011-01-15 |
Family
ID=30770951
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT08166335T ATE494907T1 (de) | 2002-07-18 | 2003-07-18 | Pharmazeutische zusammensetzungen, die immunologisch aktive herpes simplex virus proteinfragmente enthalten |
AT03765758T ATE414176T1 (de) | 2002-07-18 | 2003-07-18 | Schnelle, effiziente reinigung von hsv- spezifischen t-lymphozyten und damit identifizierte hsv-antigene |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT03765758T ATE414176T1 (de) | 2002-07-18 | 2003-07-18 | Schnelle, effiziente reinigung von hsv- spezifischen t-lymphozyten und damit identifizierte hsv-antigene |
Country Status (8)
Country | Link |
---|---|
US (7) | US7078041B2 (de) |
EP (5) | EP1523582B1 (de) |
AT (2) | ATE494907T1 (de) |
AU (1) | AU2003252052A1 (de) |
CA (1) | CA2492598C (de) |
DE (2) | DE60335755D1 (de) |
DK (2) | DK1523582T3 (de) |
WO (1) | WO2004009021A2 (de) |
Families Citing this family (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NZ509974A (en) * | 1998-08-07 | 2003-10-31 | Univ Washington | Immunological herpes simplex virus antigens and methods for use thereof |
US20090220931A1 (en) * | 2005-09-08 | 2009-09-03 | Mologen Ag | Functional in vitro immunoassay |
US20070122415A1 (en) * | 2005-11-29 | 2007-05-31 | University Of Pittsburgh Of The Commonwealth System Of Higher Education | Compound and method for suppressing retroviral replication |
WO2008011609A2 (en) | 2006-07-20 | 2008-01-24 | Vical Incorporated | Compositions and methods for vaccinating against hsv-2 |
US8460674B2 (en) * | 2009-02-07 | 2013-06-11 | University Of Washington | HSV-1 epitopes and methods for using same |
US9044447B2 (en) | 2009-04-03 | 2015-06-02 | University Of Washington | Antigenic peptide of HSV-2 and methods for using same |
RU2585961C9 (ru) | 2009-05-22 | 2016-12-27 | Дженосеа Биосайенсиз Инк. | Вакцины против вируса простого герпеса 2 типа: композиции и способы запуска иммунного ответа |
US9782474B2 (en) | 2010-11-24 | 2017-10-10 | Genocea Biosciences, Inc. | Vaccines against herpes simplex virus type 2: compositions and methods for eliciting an immune response |
JP6199878B2 (ja) | 2011-11-23 | 2017-09-20 | ジェノセア バイオサイエンシーズ, インコーポレイテッド | 単純ヘルペスウイルス2型に対する核酸ワクチン:免疫応答を誘発する組成物及び方法 |
CN104321425B (zh) | 2012-05-07 | 2018-08-10 | 株式会社Nkmax | 用于诱导和扩增源自外周血单个核细胞的自然杀伤细胞的方法 |
WO2013168978A1 (ko) * | 2012-05-07 | 2013-11-14 | 고려대학교 산학협력단 | 말초혈액단핵구 유래 자연 살해세포의 유도 및 증식 방법 |
PL2850431T3 (pl) * | 2012-05-16 | 2018-09-28 | Immune Design Corp. | Szczepionki przeciwko HSV-2 |
CN104694553B (zh) * | 2013-12-05 | 2018-04-17 | 长春百克生物科技股份公司 | 生殖器疱疹疫苗 |
US20180320230A1 (en) * | 2015-10-27 | 2018-11-08 | Arizona Board Of Regents On Behalf Of Arizona State University | High throughput identification of t-cell recognition antigens and epitopes |
JP2019537555A (ja) | 2016-09-28 | 2019-12-26 | ジェノセア バイオサイエンシーズ, インコーポレイテッド | ヘルペスを処置するための方法および組成物 |
WO2019018796A1 (en) * | 2017-07-21 | 2019-01-24 | Fred Hutchinson Cancer Research Center | VACCINE EPITOPES AGAINST HERPES SIMPLEX VIRUS RECOGNIZED SPECIFICALLY BY MEMORY T LYMPHOCYTES RESIDING IN FABRICS |
NZ766453A (en) | 2018-02-01 | 2022-02-25 | Nkmax Co Ltd | Method of producing natural killer cells and composition for treating cancer |
EP3832178B1 (de) | 2018-08-01 | 2024-05-01 | Eagle Industry Co., Ltd. | Gleitkomponente |
EP3842673A4 (de) | 2018-08-24 | 2022-05-04 | Eagle Industry Co., Ltd. | Gleitelement |
KR102589959B1 (ko) | 2018-11-30 | 2023-10-17 | 이구루코교 가부시기가이샤 | 슬라이딩 부품 |
JP7345998B2 (ja) | 2018-12-21 | 2023-09-19 | イーグル工業株式会社 | 摺動部品 |
US11933405B2 (en) | 2019-02-14 | 2024-03-19 | Eagle Industry Co., Ltd. | Sliding component |
EP4006368A4 (de) | 2019-07-26 | 2023-08-16 | Eagle Industry Co., Ltd. | Gleitkomponente |
Family Cites Families (52)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4429008B1 (en) | 1981-12-10 | 1995-05-16 | Univ California | Thiol reactive liposomes |
US4603112A (en) | 1981-12-24 | 1986-07-29 | Health Research, Incorporated | Modified vaccinia virus |
US4769330A (en) | 1981-12-24 | 1988-09-06 | Health Research, Incorporated | Modified vaccinia virus and methods for making and using the same |
US4762708A (en) * | 1982-02-18 | 1988-08-09 | University Patents, Inc. | Materials and methods for herpes simplex virus vaccination |
US4866034A (en) | 1982-05-26 | 1989-09-12 | Ribi Immunochem Research Inc. | Refined detoxified endotoxin |
US4436727A (en) | 1982-05-26 | 1984-03-13 | Ribi Immunochem Research, Inc. | Refined detoxified endotoxin product |
JPS59116229A (ja) | 1982-12-24 | 1984-07-05 | Teijin Ltd | 細胞毒性複合体を活性成分とする癌治療用剤およびその製造法 |
US7264817B1 (en) | 1983-08-30 | 2007-09-04 | Genentech, Inc. | Immunogenic composition based on a truncated derivative of a membrane bound protein and process for making it |
US4873088A (en) | 1983-09-06 | 1989-10-10 | Liposome Technology, Inc. | Liposome drug delivery method and composition |
US4618578A (en) * | 1984-07-17 | 1986-10-21 | Chiron Corporation | Expression of glycoprotein D of herpes simplex virus |
US5171568A (en) * | 1984-04-06 | 1992-12-15 | Chiron Corporation | Recombinant herpes simplex gb-gd vaccine |
US4859587A (en) * | 1984-06-04 | 1989-08-22 | Institut Merieux | Recombinant herpes simplex viruses, vaccines and methods |
US5612041A (en) | 1984-07-17 | 1997-03-18 | Chiron Corporation | Recombinant herpes simplex gD vaccine |
US4751180A (en) | 1985-03-28 | 1988-06-14 | Chiron Corporation | Expression using fused genes providing for protein product |
US4683202A (en) | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
GB8508845D0 (en) | 1985-04-04 | 1985-05-09 | Hoffmann La Roche | Vaccinia dna |
US4777127A (en) | 1985-09-30 | 1988-10-11 | Labsystems Oy | Human retrovirus-related products and methods of diagnosing and treating conditions associated with said retrovirus |
US4935233A (en) | 1985-12-02 | 1990-06-19 | G. D. Searle And Company | Covalently linked polypeptide cell modulators |
US4699784A (en) | 1986-02-25 | 1987-10-13 | Center For Molecular Medicine & Immunology | Tumoricidal methotrexate-antibody conjugate |
US4877611A (en) | 1986-04-15 | 1989-10-31 | Ribi Immunochem Research Inc. | Vaccine containing tumor antigens and adjuvants |
US5075109A (en) | 1986-10-24 | 1991-12-24 | Southern Research Institute | Method of potentiating an immune response |
GB8702816D0 (en) | 1987-02-07 | 1987-03-11 | Al Sumidaie A M K | Obtaining retrovirus-containing fraction |
US4897268A (en) | 1987-08-03 | 1990-01-30 | Southern Research Institute | Drug delivery system and method of making the same |
US5538724A (en) * | 1987-08-11 | 1996-07-23 | The Board Of Trustees For The Leland Stanford Junior Univ. | Method of control leukocyte extravasation |
WO1989001973A2 (en) | 1987-09-02 | 1989-03-09 | Applied Biotechnology, Inc. | Recombinant pox virus for immunization against tumor-associated antigens |
AP129A (en) | 1988-06-03 | 1991-04-17 | Smithkline Biologicals S A | Expression of retrovirus gag protein eukaryotic cells |
US4912094B1 (en) | 1988-06-29 | 1994-02-15 | Ribi Immunochem Research Inc. | Modified lipopolysaccharides and process of preparation |
WO1991002805A2 (en) | 1989-08-18 | 1991-03-07 | Viagene, Inc. | Recombinant retroviruses delivering vector constructs to target cells |
SE466259B (sv) | 1990-05-31 | 1992-01-20 | Arne Forsgren | Protein d - ett igd-bindande protein fraan haemophilus influenzae, samt anvaendning av detta foer analys, vacciner och uppreningsaendamaal |
TW232710B (de) * | 1991-09-13 | 1994-10-21 | American Cyanamid Co | |
KR100278157B1 (ko) * | 1992-06-25 | 2001-01-15 | 장 스테판느 | 보조약을 함유하는 백신 조성물 |
CA2169748A1 (en) * | 1993-08-20 | 1995-03-02 | Anthony G. Dilella | Hsv-2 ul26 gene, capsid proteins, immunoassays and protease inhibitors |
US5426039A (en) | 1993-09-08 | 1995-06-20 | Bio-Rad Laboratories, Inc. | Direct molecular cloning of primer extended DNA containing an alkane diol |
GB9325496D0 (en) * | 1993-12-14 | 1994-02-16 | Smithkline Beecham Biolog | Vaccines |
GB9326253D0 (en) | 1993-12-23 | 1994-02-23 | Smithkline Beecham Biolog | Vaccines |
WO1995018148A1 (en) * | 1993-12-28 | 1995-07-06 | Chiron Mimotopes Pty Ltd | T-cell epitopes |
EP0772619B2 (de) | 1994-07-15 | 2010-12-08 | The University of Iowa Research Foundation | Immunomodulatorische oligonukleotide |
UA56132C2 (uk) | 1995-04-25 | 2003-05-15 | Смітклайн Бічем Байолоджікалс С.А. | Композиція вакцини (варіанти), спосіб стабілізації qs21 відносно гідролізу (варіанти), спосіб приготування композиції вакцини |
EP0871747A1 (de) | 1996-01-02 | 1998-10-21 | Chiron Viagene, Inc. | Immunstimulierung vermittelt durch genmodifizierte dendritische zellen |
US5741492A (en) * | 1996-01-23 | 1998-04-21 | St. Jude Children's Research Hospital | Preparation and use of viral vectors for mixed envelope protein vaccines against human immunodeficiency viruses |
US5958895A (en) * | 1996-10-23 | 1999-09-28 | American Home Products Corporation | DNA vaccines for herpes simplex virus |
EP0948508A4 (de) * | 1996-11-04 | 2001-11-07 | Smithkline Beecham Corp | Kodierungssequenzen vom herpes-simplex-virus typ 2 |
NZ509974A (en) * | 1998-08-07 | 2003-10-31 | Univ Washington | Immunological herpes simplex virus antigens and methods for use thereof |
US6692752B1 (en) | 1999-09-08 | 2004-02-17 | Smithkline Beecham Biologicals S.A. | Methods of treating human females susceptible to HSV infection |
JP2003512305A (ja) * | 1999-09-30 | 2003-04-02 | ユニバーシティ オブ ワシントン | 免疫学的に重要な単純疱疹ウイルス抗原 |
US6375652B1 (en) * | 2000-05-04 | 2002-04-23 | Brymill Corporation | Cutaneous cryosurgical clamp |
DE60125537D1 (de) * | 2000-06-29 | 2007-02-08 | Corixa Corp | Zusammensetzung zur diagnose und behandlung von herpes simplex virusinfektionen |
US6821519B2 (en) * | 2000-06-29 | 2004-11-23 | Corixa Corporation | Compositions and methods for the diagnosis and treatment of herpes simplex virus infection |
WO2002056828A2 (en) * | 2000-11-29 | 2002-07-25 | University Of Rochester | Helper virus-free herpes virus amplicon particles and uses thereof |
US8092791B2 (en) * | 2001-05-23 | 2012-01-10 | University Of Rochester | Method of producing herpes simplex virus amplicons, resulting amplicons, and their use |
CA2454750C (en) * | 2001-07-31 | 2012-09-18 | David M. Koelle | Immunologically significant herpes simplex virus antigens and methods for using same |
US20030219448A1 (en) * | 2002-05-24 | 2003-11-27 | Cedars-Sinai Medical Center | Peptide epitope-based vaccine for treating herpes simplex virus infections and related diseases |
-
2003
- 2003-07-18 EP EP03765758A patent/EP1523582B1/de not_active Expired - Lifetime
- 2003-07-18 CA CA2492598A patent/CA2492598C/en not_active Expired - Fee Related
- 2003-07-18 AU AU2003252052A patent/AU2003252052A1/en not_active Abandoned
- 2003-07-18 AT AT08166335T patent/ATE494907T1/de not_active IP Right Cessation
- 2003-07-18 EP EP14195732.4A patent/EP2865386B1/de not_active Expired - Lifetime
- 2003-07-18 EP EP20100075630 patent/EP2316479B8/de not_active Expired - Lifetime
- 2003-07-18 DE DE60335755T patent/DE60335755D1/de not_active Expired - Lifetime
- 2003-07-18 EP EP20100175473 patent/EP2263686B1/de not_active Expired - Lifetime
- 2003-07-18 EP EP20080166335 patent/EP2011510B1/de not_active Expired - Lifetime
- 2003-07-18 WO PCT/US2003/022560 patent/WO2004009021A2/en active Search and Examination
- 2003-07-18 US US10/623,429 patent/US7078041B2/en not_active Expired - Fee Related
- 2003-07-18 DK DK03765758T patent/DK1523582T3/da active
- 2003-07-18 AT AT03765758T patent/ATE414176T1/de not_active IP Right Cessation
- 2003-07-18 DK DK08166335T patent/DK2011510T3/da active
- 2003-07-18 DE DE60324678T patent/DE60324678D1/de not_active Expired - Lifetime
-
2006
- 2006-02-28 US US11/364,438 patent/US7431934B2/en not_active Expired - Fee Related
-
2008
- 2008-09-18 US US12/233,280 patent/US7666434B2/en not_active Expired - Fee Related
-
2010
- 2010-01-21 US US12/691,309 patent/US8197824B2/en not_active Expired - Lifetime
-
2012
- 2012-05-14 US US13/471,272 patent/US9138473B2/en not_active Expired - Fee Related
-
2013
- 2013-03-15 US US13/842,549 patent/US20130189294A1/en not_active Abandoned
-
2015
- 2015-09-21 US US14/860,623 patent/US9675688B2/en not_active Expired - Lifetime
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ATE494907T1 (de) | Pharmazeutische zusammensetzungen, die immunologisch aktive herpes simplex virus proteinfragmente enthalten | |
NO20021479D0 (no) | Immunologiske signifikante herpes simplex virus antigener og metoder for å identifisere og å bruke dem | |
Joshi et al. | Visceral leishmaniasis: advancements in vaccine development via classical and molecular approaches | |
AR020134A1 (es) | Antigenos inmunologicos contra el virus herpes simplex y metodos para el uso de los mismos | |
WO2003011893A3 (en) | Immunologically significant herpes simplex virus antigens and methods for using same | |
CY1106152T1 (el) | Νεα ανοσογονα αντι-hiv (ανατοξινες), μεθοδοι παρασκευης και εφαρμογη στην προληψη και στην αγωγη του aids | |
WO2001082963A3 (en) | Method of identifying and producing antigen peptides and use thereof as vaccines | |
RU2324493C2 (ru) | Способ применения композиций, содержащих белки теплового шока или альфа-2-макроглобулин, для лечения рака и инфекционных болезней | |
BR9912653A (pt) | Vìrus de herpes atenuado, cepa de vìrus, célula dendrìtica, processo para produzir um célula, composição farmacêutica, uso de um vìrus, e, processo para executar a terapia de gene em um paciente humano ou animal ou para tratar ou prevenir uma infecção patogênica ou câncer para tratar paciente animal | |
WO2005116270A3 (en) | Influenza virus vaccine composition and method of use | |
WO2023147092A3 (en) | Coronavirus vaccine | |
ATE458496T1 (de) | Hiv-vakzine und anwendungsverfahren | |
HUP9904171A2 (hu) | A ragadós száj- és körömfájás vírusok immunogén peptidjei | |
Carneiro et al. | Vaccination with L. infantum chagasi nucleosomal histones confers protection against new world cutaneous leishmaniasis caused by Leishmania braziliensis | |
MXPA02010173A (es) | Antigenos de leishmania para utilizarse en la terapia y el diagnostico de leishmaniasis. | |
EA200301125A1 (ru) | Вакцины, включающие в качестве адъюванта интерферон типа i, и связанные с этим способы | |
YU99603A (sh) | Geni koji su povezani sa virulencijom parazita laišmanije | |
CN101977930B (zh) | 含核糖体蛋白质提取物(RPE)和任选的促Th1佐剂的疫苗 | |
Strahan et al. | V-REPP and plaques VZV | |
Kumar et al. | Role of Vaccines on Human Health-A Review | |
AU4300700A (en) | Inactivated cytokines for immunisation | |
Dube et al. | Kala-azar: The immunological consequences and feasibility of vaccination | |
Thomson | IMMUNOLOGICAL AND PROTECTIVE RESPONSES TO A HERPES SIMPLEX VIRUS SUBUNIT VACCINE IN A LABIAL INFECTION MODEL IN MICE. | |
RU98117675A (ru) | Лекарственный состав с иммуномодуляторным действием, содержащий пептиды и вспомогательные средства |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |