ATE493134T1 - Gefriergetrocknetes präparat mit methylcobalamin und verfahren zu seiner herstellung - Google Patents
Gefriergetrocknetes präparat mit methylcobalamin und verfahren zu seiner herstellungInfo
- Publication number
- ATE493134T1 ATE493134T1 AT04731472T AT04731472T ATE493134T1 AT E493134 T1 ATE493134 T1 AT E493134T1 AT 04731472 T AT04731472 T AT 04731472T AT 04731472 T AT04731472 T AT 04731472T AT E493134 T1 ATE493134 T1 AT E493134T1
- Authority
- AT
- Austria
- Prior art keywords
- freeze
- dried preparation
- methylcobalamin
- preparation containing
- excipient
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7135—Compounds containing heavy metals
- A61K31/714—Cobalamins, e.g. cyanocobalamin, i.e. vitamin B12
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Inorganic Chemistry (AREA)
- Dermatology (AREA)
- Biochemistry (AREA)
- Neurology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2003129251 | 2003-05-07 | ||
PCT/JP2004/005973 WO2004098614A1 (ja) | 2003-05-07 | 2004-05-06 | メチルコバラミン含有凍結乾燥製剤及びその製造方法 |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE493134T1 true ATE493134T1 (de) | 2011-01-15 |
Family
ID=33432069
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT04731472T ATE493134T1 (de) | 2003-05-07 | 2004-05-06 | Gefriergetrocknetes präparat mit methylcobalamin und verfahren zu seiner herstellung |
Country Status (11)
Country | Link |
---|---|
US (1) | US20060247203A1 (de) |
EP (1) | EP1621202B1 (de) |
JP (1) | JP4753717B2 (de) |
KR (1) | KR100732100B1 (de) |
CN (1) | CN100376251C (de) |
AT (1) | ATE493134T1 (de) |
AU (1) | AU2004236603B2 (de) |
CA (1) | CA2521928A1 (de) |
DE (1) | DE602004030781D1 (de) |
ES (1) | ES2356242T3 (de) |
WO (1) | WO2004098614A1 (de) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TWI334866B (en) * | 2002-05-29 | 2010-12-21 | Mercian Corp | Novel physiologically active substances |
CN101500571A (zh) * | 2006-08-14 | 2009-08-05 | 卫材R&D管理有限公司 | 稳定的冻干制剂 |
CN101616912A (zh) * | 2007-01-29 | 2009-12-30 | 卫材R&D管理有限公司 | 大环内酯系化合物的固体及其制造方法及其药物组合物 |
CU24142B1 (es) * | 2010-10-29 | 2015-12-23 | Troikaa Pharmaceuticals Ltd | Composiciones nasales de vitamina b12 |
CN102895200B (zh) * | 2012-11-02 | 2014-04-02 | 湖北人民制药有限公司 | 甲钴胺冻干组合物及其制备方法 |
CN107595877B (zh) * | 2016-07-12 | 2020-08-28 | 石药集团恩必普药业有限公司 | 一种含有丁苯酞的药物组合物及其在治疗als病药物中的应用 |
CN111556752A (zh) | 2017-12-28 | 2020-08-18 | 富士胶片富山化学株式会社 | 冻干制剂的制造方法 |
JP7436151B2 (ja) * | 2019-05-31 | 2024-02-21 | 小林製薬株式会社 | ビタミンb12類の光安定化方法 |
CN112494436A (zh) * | 2020-12-14 | 2021-03-16 | 卓和药业集团有限公司 | 一种注射用甲钴胺及其制备工艺 |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR7028M (de) * | 1966-06-23 | 1969-06-09 | ||
JPS55113721A (en) * | 1979-02-27 | 1980-09-02 | Eisai Co Ltd | Immunity regulator |
JPS59152327A (ja) * | 1983-02-16 | 1984-08-31 | Otsuka Pharmaceut Co Ltd | 安定な静注用総合ビタミン製剤 |
JPS62149619A (ja) * | 1985-09-05 | 1987-07-03 | Teijin Ltd | 活性型ビタミンd3類注射用組成物 |
FR2740686B1 (fr) * | 1995-11-03 | 1998-01-16 | Sanofi Sa | Formulation pharmaceutique lyophilisee stable |
FR2740973B1 (fr) * | 1995-11-15 | 1998-02-06 | Lipha | Nouvelle forme d'administration de l'hydroxocobalamine et son utilisation dans les intoxications par les cyanures |
CA2266412A1 (en) * | 1996-09-18 | 1998-03-26 | William J. Sarill | Compositions containing cobalamin and amino acids |
JP3889844B2 (ja) * | 1997-02-10 | 2007-03-07 | 龍兒 梶 | 筋萎縮性側索硬化症治療剤 |
WO2001092288A2 (en) * | 2000-05-31 | 2001-12-06 | Mayo Foundation For Medical Education And Research | Cobalamin compounds useful as antibiotic agents and as imaging agents |
-
2004
- 2004-05-06 JP JP2005505980A patent/JP4753717B2/ja not_active Expired - Lifetime
- 2004-05-06 AU AU2004236603A patent/AU2004236603B2/en not_active Ceased
- 2004-05-06 DE DE602004030781T patent/DE602004030781D1/de not_active Expired - Lifetime
- 2004-05-06 CA CA002521928A patent/CA2521928A1/en not_active Abandoned
- 2004-05-06 US US10/555,343 patent/US20060247203A1/en not_active Abandoned
- 2004-05-06 ES ES04731472T patent/ES2356242T3/es not_active Expired - Lifetime
- 2004-05-06 CN CNB2004800121087A patent/CN100376251C/zh not_active Expired - Lifetime
- 2004-05-06 EP EP04731472A patent/EP1621202B1/de not_active Expired - Lifetime
- 2004-05-06 AT AT04731472T patent/ATE493134T1/de not_active IP Right Cessation
- 2004-05-06 WO PCT/JP2004/005973 patent/WO2004098614A1/ja active Application Filing
- 2004-05-06 KR KR1020057020988A patent/KR100732100B1/ko active IP Right Grant
Also Published As
Publication number | Publication date |
---|---|
US20060247203A1 (en) | 2006-11-02 |
CN100376251C (zh) | 2008-03-26 |
AU2004236603A1 (en) | 2004-11-18 |
ES2356242T3 (es) | 2011-04-06 |
WO2004098614A1 (ja) | 2004-11-18 |
EP1621202B1 (de) | 2010-12-29 |
AU2004236603B2 (en) | 2006-12-07 |
JPWO2004098614A1 (ja) | 2006-07-13 |
KR100732100B1 (ko) | 2007-06-27 |
EP1621202A1 (de) | 2006-02-01 |
CN1784237A (zh) | 2006-06-07 |
DE602004030781D1 (de) | 2011-02-10 |
EP1621202A4 (de) | 2007-10-31 |
CA2521928A1 (en) | 2004-11-18 |
JP4753717B2 (ja) | 2011-08-24 |
KR20060011987A (ko) | 2006-02-06 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |