ATE483716T1 - Lösungsmittelfreies amorphes rapamycin - Google Patents
Lösungsmittelfreies amorphes rapamycinInfo
- Publication number
- ATE483716T1 ATE483716T1 AT05792296T AT05792296T ATE483716T1 AT E483716 T1 ATE483716 T1 AT E483716T1 AT 05792296 T AT05792296 T AT 05792296T AT 05792296 T AT05792296 T AT 05792296T AT E483716 T1 ATE483716 T1 AT E483716T1
- Authority
- AT
- Austria
- Prior art keywords
- free
- solvent
- amorphic
- rapamycin
- therapeutic agents
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
- C07D498/18—Bridged systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Transplantation (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Materials For Medical Uses (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US60532404P | 2004-08-27 | 2004-08-27 | |
PCT/US2005/030606 WO2006026531A1 (en) | 2004-08-27 | 2005-08-24 | Solvent free amorphous rapamycin |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE483716T1 true ATE483716T1 (de) | 2010-10-15 |
Family
ID=35539393
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT05792296T ATE483716T1 (de) | 2004-08-27 | 2005-08-24 | Lösungsmittelfreies amorphes rapamycin |
Country Status (7)
Country | Link |
---|---|
US (2) | US7393952B2 (de) |
EP (1) | EP1781672B1 (de) |
JP (1) | JP5117190B2 (de) |
AT (1) | ATE483716T1 (de) |
CA (1) | CA2578245C (de) |
DE (1) | DE602005024012D1 (de) |
WO (1) | WO2006026531A1 (de) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7255891B1 (en) * | 2003-02-26 | 2007-08-14 | Advanced Cardiovascular Systems, Inc. | Method for coating implantable medical devices |
US8715771B2 (en) * | 2003-02-26 | 2014-05-06 | Abbott Cardiovascular Systems Inc. | Coated stent and method of making the same |
US8663639B2 (en) | 2005-02-09 | 2014-03-04 | Santen Pharmaceutical Co., Ltd. | Formulations for treating ocular diseases and conditions |
EP1848431B1 (de) | 2005-02-09 | 2016-02-03 | Santen Pharmaceutical Co., Ltd. | Flüssige formulierungen zur behandlung von erkrankungen oder leiden |
WO2007092620A2 (en) | 2006-02-09 | 2007-08-16 | Macusight, Inc. | Stable formulations, and methods of their preparation and use |
ES2563288T3 (es) | 2006-03-23 | 2016-03-14 | Santen Pharmaceutical Co., Ltd | Rapamicina en dosis bajas para el tratamiento de enfermedades relacionadas con la permeabilidad vascular |
US20090011117A1 (en) * | 2007-07-03 | 2009-01-08 | Endotronix, Inc. | Methods for texturing a surface of an endovascular implant |
EP2307067A2 (de) | 2008-06-25 | 2011-04-13 | Boston Scientific Scimed, Inc. | Medizinische vorrichtungen mit therapeutischen mitteln |
IT1400977B1 (it) | 2010-07-01 | 2013-07-05 | Euticals Spa | Nuovi complessi di inclusione farmaceutici, solidi, solubili in acqua e le loro soluzioni acquose per uso orale, oftalmico, topico o parenterale, contenenti un macrolide ed alcune ciclodestrine. |
ES2797376T3 (es) | 2013-01-24 | 2020-12-02 | Palvella Therapeutics Inc | Composiciones para la administración transdérmica de inhibidores de mTOR |
JP6472155B2 (ja) * | 2013-04-01 | 2019-02-20 | テルモ株式会社 | ステントおよびステントデリバリーシステム |
WO2015181826A1 (en) | 2014-05-27 | 2015-12-03 | Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. | Crystalline coating and release of bioactive agents |
AU2016323425B2 (en) | 2015-09-15 | 2020-10-22 | Savage Medical, Inc. | Devices and methods for anchoring a sheath in a tissue cavity |
EP3565520A4 (de) | 2017-01-06 | 2020-08-19 | Palvella Therapeutics, Inc. | Wasserfreie zusammensetzungen von mtor-hemmern und verfahren zur verwendung |
CN108129490B (zh) * | 2017-12-11 | 2020-12-01 | 成都海创药业有限公司 | 一种制备依维莫司无定形固体的方法 |
EP3817743A4 (de) | 2018-07-02 | 2022-07-06 | Palvella Therapeutics, Inc. | Wasserfreie zusammensetzungen von mtor-hemmern und verfahren zur verwendung |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ZA737247B (en) * | 1972-09-29 | 1975-04-30 | Ayerst Mckenna & Harrison | Rapamycin and process of preparation |
GB9221220D0 (en) * | 1992-10-09 | 1992-11-25 | Sandoz Ag | Organic componds |
FR2736550B1 (fr) * | 1995-07-14 | 1998-07-24 | Sandoz Sa | Composition pharmaceutique sous la forme d'une dispersion solide comprenant un macrolide et un vehicule |
US6384213B1 (en) * | 1998-10-23 | 2002-05-07 | Ranbaxy Laboratories Limited | Process for preparing a pure, pharmacopoeial grade amorphous form of cefuroxime axetil |
WO2002057228A1 (en) * | 2001-01-17 | 2002-07-25 | Biocon India Limited | Atorvastatin calcium |
ZA200408744B (en) * | 2002-04-22 | 2005-11-10 | Res Found Itsuu Lab | Drugs for treating vascular diseases. |
EP1539043B1 (de) * | 2002-09-20 | 2013-12-18 | Innovational Holdings, LLC | Expandierbare medizinische vorrichtung mit öffnungen zur abgabe multipler heilmittel |
DE10244847A1 (de) * | 2002-09-20 | 2004-04-01 | Ulrich Prof. Dr. Speck | Medizinische Vorrichtung zur Arzneimittelabgabe |
US20040093064A1 (en) * | 2002-11-12 | 2004-05-13 | Gjalt Bosma | Drug eluting stent graft combination |
SG144165A1 (en) * | 2003-07-25 | 2008-07-29 | Wyeth Corp | Cci-779 lyophilized formulations |
CN1874771A (zh) * | 2003-09-03 | 2006-12-06 | 惠氏公司 | 3-羟基-2-(羟甲基)-2-甲基丙酸的非晶态雷帕霉素42-酯及其包含相同化合物的药用组合物 |
-
2005
- 2005-08-24 CA CA2578245A patent/CA2578245C/en not_active Expired - Fee Related
- 2005-08-24 EP EP05792296A patent/EP1781672B1/de not_active Not-in-force
- 2005-08-24 JP JP2007530211A patent/JP5117190B2/ja active Active
- 2005-08-24 AT AT05792296T patent/ATE483716T1/de not_active IP Right Cessation
- 2005-08-24 DE DE602005024012T patent/DE602005024012D1/de active Active
- 2005-08-24 US US11/210,393 patent/US7393952B2/en active Active
- 2005-08-24 WO PCT/US2005/030606 patent/WO2006026531A1/en active Application Filing
-
2008
- 2008-05-27 US US12/127,467 patent/US20080227982A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
DE602005024012D1 (de) | 2010-11-18 |
CA2578245C (en) | 2013-10-29 |
JP2008511642A (ja) | 2008-04-17 |
WO2006026531A1 (en) | 2006-03-09 |
US20060128739A1 (en) | 2006-06-15 |
CA2578245A1 (en) | 2006-03-09 |
JP5117190B2 (ja) | 2013-01-09 |
EP1781672B1 (de) | 2010-10-06 |
US7393952B2 (en) | 2008-07-01 |
EP1781672A1 (de) | 2007-05-09 |
US20080227982A1 (en) | 2008-09-18 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |