ATE478602T1 - Nukleinsäuren und polypeptide zur diagnose und behandlung von schwangerschaftskomplikationen - Google Patents
Nukleinsäuren und polypeptide zur diagnose und behandlung von schwangerschaftskomplikationenInfo
- Publication number
- ATE478602T1 ATE478602T1 AT05858653T AT05858653T ATE478602T1 AT E478602 T1 ATE478602 T1 AT E478602T1 AT 05858653 T AT05858653 T AT 05858653T AT 05858653 T AT05858653 T AT 05858653T AT E478602 T1 ATE478602 T1 AT E478602T1
- Authority
- AT
- Austria
- Prior art keywords
- protein
- receptor
- precursor
- polypeptide
- alpha
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/689—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to pregnancy or the gonads
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/32—Cardiovascular disorders
- G01N2800/321—Arterial hypertension
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/36—Gynecology or obstetrics
- G01N2800/368—Pregnancy complicated by disease or abnormalities of pregnancy, e.g. preeclampsia, preterm labour
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Organic Chemistry (AREA)
- Analytical Chemistry (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Pathology (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- Cell Biology (AREA)
- General Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- Reproductive Health (AREA)
- Pregnancy & Childbirth (AREA)
- Gynecology & Obstetrics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US63627504P | 2004-12-15 | 2004-12-15 | |
PCT/US2005/045805 WO2007053161A2 (en) | 2004-12-15 | 2005-12-15 | Nucleic acids and polypeptides useful for diagnosing and treating complications of pregnancy |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE478602T1 true ATE478602T1 (de) | 2010-09-15 |
Family
ID=38006337
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT05858653T ATE478602T1 (de) | 2004-12-15 | 2005-12-15 | Nukleinsäuren und polypeptide zur diagnose und behandlung von schwangerschaftskomplikationen |
Country Status (12)
Country | Link |
---|---|
US (1) | US7955805B2 (de) |
EP (1) | EP1839057B1 (de) |
JP (1) | JP2008523816A (de) |
KR (1) | KR20070092737A (de) |
CN (1) | CN101299962A (de) |
AT (1) | ATE478602T1 (de) |
AU (1) | AU2005337873A1 (de) |
BR (1) | BRPI0519096A2 (de) |
CA (1) | CA2591142A1 (de) |
DE (1) | DE602005023216D1 (de) |
HK (1) | HK1115286A1 (de) |
WO (1) | WO2007053161A2 (de) |
Families Citing this family (28)
Publication number | Priority date | Publication date | Assignee | Title |
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EP1804836B1 (de) | 2004-09-24 | 2010-11-17 | Beth Israel Deaconess Medical Center | Verfahren zur diagnose und behandlung von schwangerschaftsskomplikationen |
EP1839056B1 (de) * | 2004-12-21 | 2011-08-03 | Yale University | Präeklampsie-diagnose |
US7230561B2 (en) * | 2005-01-27 | 2007-06-12 | Micron Technology, Inc. | Programmable integrating ramp generator and method of operating the same |
EP1866441A4 (de) * | 2005-03-24 | 2009-11-11 | Beth Israel Hospital | Verfahren zur diagnose von trisomie 13 beim fötus oder des risikos von trisomie 13 beim fötus während der schwangerschaft |
US20100190192A1 (en) * | 2005-09-15 | 2010-07-29 | Victor Voroteliak | Method of diagnosing pre-eclampsia |
US20090286271A1 (en) * | 2006-05-31 | 2009-11-19 | Karumanchi Ananth S | Methods of Diagnosing and Treating Complications of Pregnancy |
EP2126564B1 (de) * | 2007-01-25 | 2012-10-03 | Crc For Asthma And Airways Ltd | Diagnoseverfahren |
US20110129845A1 (en) * | 2007-01-29 | 2011-06-02 | Crc For Asthma And Airways Ltd. | Method of diagnosis |
EP2037278A1 (de) * | 2007-09-11 | 2009-03-18 | F.Hoffmann-La Roche Ag | Gefäßmarker bei der Neumodellierung von Herzkrankheiten |
US20110171650A1 (en) * | 2008-09-16 | 2011-07-14 | University Of Pittsburgh-Of The Commonwealth System Of Higher Education | Gene expression related to preeclampsia |
CN104777307B (zh) | 2008-10-31 | 2019-10-18 | 耶鲁大学 | 先兆子痫检测和治疗的方法和组合物 |
CA2748852C (en) * | 2009-01-28 | 2019-05-28 | Industrial Technology Research Institute | Biomarkers associated with nephropathy |
MX2013003662A (es) * | 2010-10-07 | 2013-05-01 | Astute Medical Inc | Metodos y composiciones para diagnostico y pronostico de lesion renal e insuficiencia renal. |
ES2667013T3 (es) | 2010-11-29 | 2018-05-09 | Mote Marine Laboratory, Inc. | Determinación de las características sexuales de peces usando hormonas peptídicas |
CN102192987B (zh) * | 2011-02-25 | 2014-04-02 | 复旦大学附属上海市第五人民医院 | 一种用于妊娠高血压疾病诊断的试剂盒 |
KR101114446B1 (ko) * | 2011-02-25 | 2012-02-24 | 건국대학교 산학협력단 | 프로테오믹스기법을 이용한 임신중독 특이 표지 단백질 및 진단방법 |
ES2614059T3 (es) | 2011-03-17 | 2017-05-29 | Cedars-Sinai Medical Center | Biomarcador de diagnóstico para predecir las mujeres en riesgo de parto prematuro |
KR20140106550A (ko) * | 2011-11-30 | 2014-09-03 | 에이전시 포 사이언스, 테크놀로지 앤드 리서치 | 생물학적 모니터링을 위한 gm1 갱글리오사이드와 아넥신 ⅴ 마이크로입자 폴리펩타이드 비율 |
JP2015505368A (ja) * | 2012-01-06 | 2015-02-19 | ビージー メディシン, インコーポレイテッド | 妊娠高血圧腎症および関連状態のリスク評価および検出のためのガレクチン−3の使用 |
CN104634982B (zh) * | 2013-11-06 | 2016-08-17 | 中国科学院上海生命科学研究院 | Vegf-c在制备败血症及重症细菌感染诊断试剂中的用途 |
CN103760340B (zh) * | 2014-01-28 | 2016-11-23 | 成都创宜生物科技有限公司 | 以flrg作为标志物制备检测工具的应用及检测工具 |
AU2015243171B2 (en) | 2014-04-10 | 2020-10-15 | Yale University | Methods and compositions for detecting misfolded proteins |
PL3311158T3 (pl) | 2015-06-19 | 2023-11-27 | Sera Prognostics, Inc. | Pary biomarkerów do przewidywania przedwczesnego porodu |
CN106771266A (zh) * | 2017-01-12 | 2017-05-31 | 广州市丰华生物工程有限公司 | 抑制素a定量检测试剂盒及其制备方法 |
JP6895165B2 (ja) * | 2017-06-06 | 2021-06-30 | 知和 松浦 | α1−アンチキモトリプシンを含むバイオマーカー |
US20210325400A1 (en) * | 2020-04-16 | 2021-10-21 | Denali K. Dahl | Preeclampsia diagnostic devices, systems and methods |
CN111951969A (zh) * | 2020-08-05 | 2020-11-17 | 中翰盛泰生物技术股份有限公司 | Hbp在高危妊娠预测中的应用 |
CN114075281B (zh) * | 2021-11-16 | 2023-04-18 | 福州迈新生物技术开发有限公司 | 抗Inhibin-α蛋白单克隆抗体、细胞系及其制备方法和应用 |
Family Cites Families (45)
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US5079171A (en) | 1988-09-15 | 1992-01-07 | Adeza Biomedical Corporation | Determining pregnancy induced hypertension and eclampsia by immunoassay of cellular fibronectin |
US5240848A (en) * | 1988-11-21 | 1993-08-31 | Monsanto Company | Dna sequences encoding human vascular permeability factor having 189 amino acids |
US5238819A (en) * | 1988-12-14 | 1993-08-24 | The Regents Of The University Of California | Diagnostic assay for the detection of preeclampsia |
US5332671A (en) * | 1989-05-12 | 1994-07-26 | Genetech, Inc. | Production of vascular endothelial cell growth factor and DNA encoding same |
US5219739A (en) * | 1989-07-27 | 1993-06-15 | Scios Nova Inc. | DNA sequences encoding bVEGF120 and hVEGF121 and methods for the production of bovine and human vascular endothelial cell growth factors, bVEGF120 and hVEGF121 |
US5194596A (en) * | 1989-07-27 | 1993-03-16 | California Biotechnology Inc. | Production of vascular endothelial cell growth factor |
US5660827A (en) * | 1992-03-05 | 1997-08-26 | Board Of Regents, The University Of Texas System | Antibodies that bind to endoglin |
AU4025193A (en) | 1992-04-08 | 1993-11-18 | Cetus Oncology Corporation | Humanized C-erbB-2 specific antibodies |
US5763441A (en) * | 1992-11-13 | 1998-06-09 | Sugen, Inc. | Compounds for the treatment of disorders related to vasculogenesis and/or angiogenesis |
US5712395A (en) * | 1992-11-13 | 1998-01-27 | Yissum Research Development Corp. | Compounds for the treatment of disorders related to vasculogenesis and/or angiogenesis |
US6410322B1 (en) * | 1993-07-27 | 2002-06-25 | Hybridon Inc | Antisense oligonucleotide inhibition of vascular endothelial growth factor expression |
US5861499A (en) | 1994-02-10 | 1999-01-19 | Imclone Systems Incorporated | Nucleic acid molecules encoding the variable or hypervariable region of a monoclonal antibody that binds to an extracellular domain |
US5543138A (en) * | 1994-03-10 | 1996-08-06 | Genetics Institute, Inc. | Methods of diagnosing and treating preeclampsia |
GB9512994D0 (en) * | 1995-06-26 | 1995-08-30 | Brf International | Method for quantitative measurement of an enzyme linked immunosorbent assay |
US6361946B1 (en) * | 1997-02-05 | 2002-03-26 | Licentia Ltd | Vascular endothelial growth factor C (VEGF-C) protein and gene, mutants thereof, and uses thereof |
US5830879A (en) * | 1995-10-02 | 1998-11-03 | St. Elizabeth's Medical Center Of Boston, Inc. | Treatment of vascular injury using vascular endothelial growth factor |
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US6399585B1 (en) * | 1996-05-15 | 2002-06-04 | Janet E. Larson | In Utero treatment of CFTR-related deficiencies |
ES2169864T3 (es) * | 1996-05-31 | 2002-07-16 | Health Research Inc | Anticuerpos monoclonales anti-endoglina y su uso en terapia anti-angiogenesis. |
US6620590B2 (en) * | 1996-07-11 | 2003-09-16 | Isis Innovation Limited | Diagnosis of pre-eclampsia |
EP0951298A1 (de) | 1996-12-23 | 1999-10-27 | Cambridge University Technical Services Limited | Diagnose und behandlung von pathologischen schwangerschaften |
WO1998040747A1 (en) * | 1997-03-07 | 1998-09-17 | Mount Sinai Hospital Corporation | Methods to diagnose a required regulation of trophoblast invasion |
EP1417971A3 (de) | 1998-09-09 | 2004-06-30 | Scios Inc. | Verwendung eines angiogenen Faktors zur Behandlung von mikrovaskulären Angiopathien |
US6677300B1 (en) * | 1998-09-09 | 2004-01-13 | Scios, Inc. | Treatment of microvascular angiopathies |
US7030083B2 (en) * | 1998-09-09 | 2006-04-18 | University Of Washington | Treatment of eclampsia and preeclampsia |
US6245577B1 (en) * | 1998-09-11 | 2001-06-12 | Midland Bioproducts Corporation | IgG antibody testing method |
EP1016726A1 (de) * | 1998-12-30 | 2000-07-05 | Introgene B.V. | Gentherapie zur Förderung der Angiogenesis |
GB0008269D0 (en) * | 2000-04-05 | 2000-05-24 | Astrazeneca Ab | Combination chemotherapy |
GB0026823D0 (en) | 2000-11-02 | 2000-12-20 | King S College London | Diagnosis of pre-eclampsia |
WO2002070535A1 (en) * | 2001-03-01 | 2002-09-12 | Isis Pharmaceuticals, Inc. | Antisense modulation of recql5 expression |
JP2005532036A (ja) * | 2002-01-09 | 2005-10-27 | 理化学研究所 | 癌プロフィール |
ES2440651T3 (es) * | 2002-07-19 | 2014-01-29 | Beth Israel Deaconess Medical Center | Método para diagnosticar preeclampsia |
US7335362B2 (en) * | 2002-07-19 | 2008-02-26 | Beth Israel Deaconess Medical Center | Methods of treating pre-eclampsia or eclampsia |
US7435419B2 (en) | 2002-07-19 | 2008-10-14 | Beth Israel Deaconess Medical Center | Methods of diagnosing and treating pre-eclampsia or eclampsia |
TW200413725A (en) * | 2002-09-30 | 2004-08-01 | Oncotherapy Science Inc | Method for diagnosing non-small cell lung cancers |
CN101260429B (zh) * | 2003-01-17 | 2011-03-30 | 香港中文大学 | 作为妊娠相关病症的诊断标志物的循环mRNA |
US20050266409A1 (en) * | 2003-02-04 | 2005-12-01 | Wyeth | Compositions and methods for diagnosing, preventing, and treating cancers |
US7191068B2 (en) * | 2003-03-25 | 2007-03-13 | Proteogenix, Inc. | Proteomic analysis of biological fluids |
DE10333105B3 (de) * | 2003-07-21 | 2005-05-25 | OCé PRINTING SYSTEMS GMBH | Einrichtung zur Einstellung der Spannung einer Materialbahn, die durch eine die Materialbahn bearbeitende Prozessstation bewegt wird |
US7323346B2 (en) * | 2003-08-14 | 2008-01-29 | The General Hospital Corporation | Screening for gestational disorders |
WO2005031364A1 (en) * | 2003-09-23 | 2005-04-07 | The General Hospital Corporation | Screening for gestational disorders |
EP1804836B1 (de) | 2004-09-24 | 2010-11-17 | Beth Israel Deaconess Medical Center | Verfahren zur diagnose und behandlung von schwangerschaftsskomplikationen |
US7740849B2 (en) * | 2004-09-24 | 2010-06-22 | Beth Israel Deaconess Medical Center | Use of compounds that bind soluble endoglin and SFLT-1 for the treatment of pregnancy related hypertensive disorders |
EP1839056B1 (de) | 2004-12-21 | 2011-08-03 | Yale University | Präeklampsie-diagnose |
AU2007293475A1 (en) | 2006-05-31 | 2008-03-13 | Beth Israel Deaconess Medical Center | Methods of diagnosing and treating complications of pregnancy |
-
2005
- 2005-12-15 JP JP2007546973A patent/JP2008523816A/ja active Pending
- 2005-12-15 AU AU2005337873A patent/AU2005337873A1/en not_active Abandoned
- 2005-12-15 KR KR1020077016078A patent/KR20070092737A/ko not_active Application Discontinuation
- 2005-12-15 EP EP05858653A patent/EP1839057B1/de active Active
- 2005-12-15 WO PCT/US2005/045805 patent/WO2007053161A2/en active Application Filing
- 2005-12-15 CA CA002591142A patent/CA2591142A1/en not_active Abandoned
- 2005-12-15 AT AT05858653T patent/ATE478602T1/de not_active IP Right Cessation
- 2005-12-15 DE DE602005023216T patent/DE602005023216D1/de active Active
- 2005-12-15 CN CNA2005800483839A patent/CN101299962A/zh active Pending
- 2005-12-15 US US11/300,928 patent/US7955805B2/en active Active
- 2005-12-15 BR BRPI0519096-7A patent/BRPI0519096A2/pt not_active IP Right Cessation
-
2008
- 2008-04-02 HK HK08103714.1A patent/HK1115286A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
US7955805B2 (en) | 2011-06-07 |
EP1839057A4 (de) | 2008-12-31 |
US20060166277A1 (en) | 2006-07-27 |
AU2005337873A1 (en) | 2007-05-10 |
BRPI0519096A2 (pt) | 2008-12-23 |
CN101299962A (zh) | 2008-11-05 |
EP1839057A2 (de) | 2007-10-03 |
WO2007053161A3 (en) | 2007-11-29 |
HK1115286A1 (en) | 2008-11-28 |
KR20070092737A (ko) | 2007-09-13 |
DE602005023216D1 (de) | 2010-10-07 |
WO2007053161A2 (en) | 2007-05-10 |
JP2008523816A (ja) | 2008-07-10 |
CA2591142A1 (en) | 2007-05-10 |
EP1839057B1 (de) | 2010-08-25 |
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Legal Events
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RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |