ATE47853T1 - 5,6-difluornaphtyridine und 5,6,8trifluorchinoline verwendbar als antibakterielle mittel. - Google Patents

5,6-difluornaphtyridine und 5,6,8trifluorchinoline verwendbar als antibakterielle mittel.

Info

Publication number: ATE47853T1
Authority: AT; Austria
Prior art keywords: difluoraphtyridine; usable; antibacterial agents; antibacterial; agents
Prior art date: 1985-04-18

Application number

AT86302812T

Other languages

English (en)

Inventor

Thomas F Mich

John M Domagala

Jeffrey B Nichols

Original Assignee

Warner Lambert Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1985-04-18

Filing date

1986-04-15

Publication date

1989-11-15

1986-04-15 Application filed by Warner Lambert Co filed Critical Warner Lambert Co

1989-11-15 Application granted granted Critical

1989-11-15 Publication of ATE47853T1 publication Critical patent/ATE47853T1/de

Links

DFYPWUZXTWLPSC-UHFFFAOYSA-N 5,6,8-trifluoroquinoline Chemical compound N1=CC=CC2=C(F)C(F)=CC(F)=C21 DFYPWUZXTWLPSC-UHFFFAOYSA-N 0.000 title 1
239000003242 anti bacterial agent Substances 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/10—Spiro-condensed systems

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Oncology (AREA)
Pharmacology & Pharmacy (AREA)
Communicable Diseases (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
Plural Heterocyclic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Quinoline Compounds (AREA)

AT86302812T 1985-04-18 1986-04-15 5,6-difluornaphtyridine und 5,6,8trifluorchinoline verwendbar als antibakterielle mittel. ATE47853T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US06/724,442 US4657913A (en)	1985-04-18	1985-04-18	Trifluoro- quinoline -3- carboxylic acids and their use as anti-bacterial agents
EP86302812A EP0202763B1 (de)	1985-04-18	1986-04-15	5,6-Difluornaphtyridine und 5,6,8-Trifluorchinoline verwendbar als antibakterielle Mittel

Publications (1)

Publication Number	Publication Date
ATE47853T1 true ATE47853T1 (de)	1989-11-15

Family

ID=24910460

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT86302812T ATE47853T1 (de)	1985-04-18	1986-04-15	5,6-difluornaphtyridine und 5,6,8trifluorchinoline verwendbar als antibakterielle mittel.

Country Status (22)

Country	Link
US (1)	US4657913A (de)
EP (1)	EP0202763B1 (de)
JP (1)	JPS61243077A (de)
KR (1)	KR890005199B1 (de)
CN (1)	CN1012064B (de)
AR (1)	AR240458A1 (de)
AT (1)	ATE47853T1 (de)
AU (1)	AU587811B2 (de)
DD (1)	DD244553A5 (de)
DE (1)	DE3666820D1 (de)
DK (1)	DK172786A (de)
ES (1)	ES8800160A1 (de)
FI (1)	FI861574A (de)
GR (1)	GR860998B (de)
HU (1)	HU195498B (de)
IL (1)	IL78528A (de)
NO (1)	NO166080C (de)
NZ (1)	NZ215868A (de)
OA (1)	OA08236A (de)
PH (1)	PH23770A (de)
PT (1)	PT82414B (de)
ZA (1)	ZA862388B (de)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IE58742B1 (en) *	1984-07-20	1993-11-05	Warner Lambert Co	Substituted-9-fluoro-3-methyl-7-oxo-2,3-dihydro-7h-pyrido[1,2,3-de] [1,4]benzoxauine-6-carboxylic acids; sibstituted-5-amino-6-6fluoro-4-oxo.1,4-dihydroquinoline-3 carboxylic acids; substituted-5-amino-6-fluoro-1,4-dihydro-4-oxo-1.8-naphthyridine-3-carboxylic acids; derivatives thereof; pharmaceutical compositions comprising the compounds; and processes for producing the compounds
EP0207420B1 (de) *	1985-06-26	1992-05-06	Daiichi Pharmaceutical Co., Ltd.	Pyridoncarbonsäurederivate
AU594983B2 (en) *	1985-10-29	1990-03-22	Dainippon Pharmaceutical Co. Ltd.	Novel quinoline derivatives and processes for preparation thereof
DE3705621C2 (de) *	1986-02-25	1997-01-09	Otsuka Pharma Co Ltd	Heterocyclisch substituierte Chinoloncarbonsäurederivate
EP0242789A3 (de) *	1986-04-25	1990-09-05	Dainippon Pharmaceutical Co., Ltd.	Chinolinderivate und Verfahren zu ihrer Herstellung
GB8612137D0 (en) *	1986-05-19	1986-06-25	Fujisawa Pharmaceutical Co	Quinolone compounds
FR2607506B1 (fr) *	1986-12-02	1989-01-06	Rhone Poulenc Sante	Nouveaux derives de l'isoindolinone, leur preparation et les compositions pharmaceutiques qui les contiennent
FR2607503B1 (fr) *	1986-12-02	1989-02-24	Rhone Poulenc Sante	Nouveaux derives de l'isoindolinone, leur preparation et les compositions pharmaceutiques qui les contiennent
FR2607504B1 (fr) *	1986-12-02	1989-01-27	Rhone Poulenc Sante	Nouveaux derives de l'isoindolinone, leur preparation et les compositions pharmaceutiques qui les contiennent
DE3711193A1 (de) *	1987-04-02	1988-10-13	Bayer Ag	5-substituierte chinolon- und naphthyridoncarbonsaeure-derivate
US5290934A (en) *	1987-04-16	1994-03-01	Otsuka Pharmaceutical Company, Limited	Benzoheterocyclic compounds
US5563138A (en) *	1987-04-16	1996-10-08	Otsuka Pharmaceutical Company, Limited	Benzoheterocyclic compounds
US4851418A (en) *	1987-08-21	1989-07-25	Warner-Lambert Company	Naphthyridine antibacterial agents containing an α-amino acid in the side chain of the 7-substituent
JPH0794452B2 (ja) *	1987-10-16	1995-10-11	大日本製薬株式会社	新規ピリドンカルボン酸誘導体、そのエステルおよびその塩
WO1989005643A1 (en) *	1987-12-18	1989-06-29	Pfizer Inc.	Heterocyclic-substituted quinoline-carboxylic acids
DE3814517A1 (de) *	1988-02-05	1989-08-17	Bayer Ag	Chinolon- und naphthyridoncarbonsaeurederivate, verfahren zu ihrer herstellung und sie enthaltende antibakterielle mittel und futterzusatzstoffe
MY105136A (en)	1988-04-27	1994-08-30	Daiichi Seiyaku Co	Optically active pyridonecarboxylic acid derivatives.
DE3906365A1 (de) *	1988-07-15	1990-01-18	Bayer Ag	7-(1-pyrrolidinyl)-3-chinolon- und -naphthyridoncarbonsaeure-derivate, verfahren sowie substituierte (oxa)diazabicyclooctane und -nonane als zwischenprodukte zu ihrer herstellung, und sie enthaltende antibakterielle mittel und futterzusatzstoffe
US4992449A (en) *	1990-02-01	1991-02-12	American Cyanamid Company	7-(substituted)cycloalkylamino-1-(substituted)-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acids
FR2692577B1 (fr) *	1992-05-26	1996-02-02	Bouchara Sa	Nouvelles quinolones fluorees, leur procede de preparation et les compositions pharmaceutiques en renfermant.
TW425394B (en) *	1996-04-24	2001-03-11	Daiichi Seiyaku Co	Antimicrobial quinolone derivatives having 3-(N-cycloalkyl) aminomethylpyrrolidine group

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3963736A (en) *	1970-01-28	1976-06-15	Sumitomo Chemical Company, Limited	Preparation of 1-(lower alkyl)-1,4-dihydro-7-methyl-4-oxo-1,8-naphthyridine-3-carboxylic acids
US3907808A (en) *	1971-05-17	1975-09-23	Sterling Drug Inc	1,4-Dihydro-4-oxo-7-pyridyl-3-quinolinecarboxylic acid derivatives
US4292317A (en) *	1977-09-20	1981-09-29	Laboratorie Roger Bellon	1,4-Dihydro-quinoline-3-carboxylic acid derivatives, process for their preparation and compositions containing them
JPS5845426B2 (ja) *	1978-09-29	1983-10-08	杏林製薬株式会社	置換キノリンカルボン酸誘導体
SE440354B (sv) *	1981-02-19	1985-07-29	Kyorin Seiyaku Kk	Kinolinkarboxylsyraderivat
ES8304117A1 (es) *	1981-06-11	1983-02-16	Warner Lambert Co	"un procedimiento para preparar sales de compuestos de naftiridina y quinoleina".
US4477449A (en) *	1982-04-19	1984-10-16	Warner-Lambert Company	Certain 1,8-naphthyridine compounds useful as antibacterial agents
IE55898B1 (en) *	1982-09-09	1991-02-14	Warner Lambert Co	Antibacterial agents
IE58742B1 (en) *	1984-07-20	1993-11-05	Warner Lambert Co	Substituted-9-fluoro-3-methyl-7-oxo-2,3-dihydro-7h-pyrido[1,2,3-de] [1,4]benzoxauine-6-carboxylic acids; sibstituted-5-amino-6-6fluoro-4-oxo.1,4-dihydroquinoline-3 carboxylic acids; substituted-5-amino-6-fluoro-1,4-dihydro-4-oxo-1.8-naphthyridine-3-carboxylic acids; derivatives thereof; pharmaceutical compositions comprising the compounds; and processes for producing the compounds
AU4042085A (en) *	1985-03-27	1986-10-02	Brugnoli, Angelo	Energy system using hydrostatic pressure air compressor

1985
- 1985-04-18 US US06/724,442 patent/US4657913A/en not_active Expired - Fee Related
1986
- 1986-04-01 ZA ZA862388A patent/ZA862388B/xx unknown
- 1986-04-03 AU AU55615/86A patent/AU587811B2/en not_active Ceased
- 1986-04-14 FI FI861574A patent/FI861574A/fi not_active Application Discontinuation
- 1986-04-15 EP EP86302812A patent/EP0202763B1/de not_active Expired
- 1986-04-15 DE DE8686302812T patent/DE3666820D1/de not_active Expired
- 1986-04-15 DD DD86289148A patent/DD244553A5/de not_active IP Right Cessation
- 1986-04-15 GR GR860998A patent/GR860998B/el unknown
- 1986-04-15 AT AT86302812T patent/ATE47853T1/de not_active IP Right Cessation
- 1986-04-16 IL IL78528A patent/IL78528A/xx unknown
- 1986-04-16 DK DK172786A patent/DK172786A/da active IP Right Grant
- 1986-04-17 PH PH33665A patent/PH23770A/en unknown
- 1986-04-17 NO NO861509A patent/NO166080C/no unknown
- 1986-04-17 OA OA58838A patent/OA08236A/xx unknown
- 1986-04-17 JP JP61087237A patent/JPS61243077A/ja active Pending
- 1986-04-17 NZ NZ215868A patent/NZ215868A/xx unknown
- 1986-04-17 AR AR303682A patent/AR240458A1/es active
- 1986-04-17 HU HU861617A patent/HU195498B/hu not_active IP Right Cessation
- 1986-04-17 PT PT82414A patent/PT82414B/pt not_active IP Right Cessation
- 1986-04-18 KR KR1019860002997A patent/KR890005199B1/ko not_active IP Right Cessation
- 1986-04-18 ES ES554142A patent/ES8800160A1/es not_active Expired
- 1986-04-18 CN CN86102683A patent/CN1012064B/zh not_active Expired

Also Published As

Publication number	Publication date
FI861574A (fi)	1986-10-19
DE3666820D1 (en)	1989-12-14
HUT41020A (en)	1987-03-30
HU195498B (en)	1988-05-30
CN1012064B (zh)	1991-03-20
NO166080C (no)	1991-05-29
NO861509L (no)	1986-10-20
KR860008164A (ko)	1986-11-12
ES8800160A1 (es)	1987-10-16
KR890005199B1 (ko)	1989-12-18
NO166080B (no)	1991-02-18
IL78528A (en)	1990-09-17
EP0202763A1 (de)	1986-11-26
NZ215868A (en)	1988-08-30
FI861574A0 (fi)	1986-04-14
ZA862388B (en)	1987-11-25
PT82414B (pt)	1988-05-27
DK172786D0 (da)	1986-04-16
AU587811B2 (en)	1989-08-31
DD244553A5 (de)	1987-04-08
OA08236A (en)	1987-10-30
EP0202763B1 (de)	1989-11-08
GR860998B (en)	1986-08-12
ES554142A0 (es)	1987-10-16
CN86102683A (zh)	1986-12-03
PT82414A (en)	1986-05-01
US4657913A (en)	1987-04-14
PH23770A (en)	1989-11-03
IL78528A0 (en)	1986-08-31
AU5561586A (en)	1986-10-23
AR240458A1 (es)	1990-04-30
JPS61243077A (ja)	1986-10-29
DK172786A (da)	1986-10-19

Legal Events

Date	Code	Title	Description
1990-04-15	UEP	Publication of translation of european patent specification
1993-01-15	REN	Ceased due to non-payment of the annual fee

Publication	Publication Date	Title
DE3684108D1 (de)	1992-04-09	Zementformende mittel.
ATE47853T1 (de)	1989-11-15	5,6-difluornaphtyridine und 5,6,8trifluorchinoline verwendbar als antibakterielle mittel.
DE3688895D1 (de)	1993-09-23	Kosmetisches mittel.
DE3680833D1 (de)	1991-09-19	Mikrobizide mittel.
ATE103278T1 (de)	1994-04-15	Fungizides mittel.
DE3485162D1 (de)	1991-11-21	Als antibakterielle mittel verwendbare aminomethyloxooxazolidinyl-benzol-derivate.
DE3585575D1 (de)	1992-04-16	Blutstillendes mittel.
DE3575296D1 (de)	1990-02-15	Pyrazolkarboxamidabkoemmlinge, deren herstellung und diese enthaltende bakterientoetende mittel.
DE3682091D1 (de)	1991-11-28	Trichostatine a und c als antikrebsmittel.
DE68914495D1 (de)	1994-05-19	Antihypercholesterolemisches Mittel.
DE3679764D1 (de)	1991-07-18	Zaepfchen und grundlage dafuer.
DE3671010D1 (de)	1990-06-13	Antiallergische mittel.
DE3767075D1 (de)	1991-02-07	Herbizides mittel.
DE3878774D1 (de)	1993-04-08	Paraherquamid und dihydroparaherquamid als antiparasitaere mittel.
DE3682908D1 (de)	1992-01-23	Fungizides mittel.
DE3782636D1 (de)	1992-12-17	Isoindolin-1-on-derivat und antiarrhythmisches mittel.
DE3677826D1 (de)	1991-04-11	Antiulceroese mittel und quassinoide.
DE3779842D1 (de)	1992-07-23	Antiallergisches mittel.
DE69010754D1 (de)	1994-08-25	Fungizide Mittel.
DE3889198D1 (de)	1994-05-26	Cephalosporinverbindungen und antibakterielle Mittel.
ATE100094T1 (de)	1994-01-15	Imidazolantiarrythmische mittel.
ATE45856T1 (de)	1989-09-15	Aminoalkanphosphonsaeure und derivate davon als fungizide mittel.
DE68919512D1 (de)	1995-01-12	Chinoxalin-Derivate und antiulzerierendes Mittel.
DE69009706D1 (de)	1994-07-14	Thrombolytische Mittel.
ATE48995T1 (de)	1990-01-15	Fluorazolyl-propanol-derivate als mikrobizide und wuchsregulierende mittel.