ATE474851T1 - Verfahren zur identifizierung antigener peptide - Google Patents

Verfahren zur identifizierung antigener peptide

Info

Publication number
ATE474851T1
ATE474851T1 AT07011493T AT07011493T ATE474851T1 AT E474851 T1 ATE474851 T1 AT E474851T1 AT 07011493 T AT07011493 T AT 07011493T AT 07011493 T AT07011493 T AT 07011493T AT E474851 T1 ATE474851 T1 AT E474851T1
Authority
AT
Austria
Prior art keywords
methods
utilized
sequence
cells
antigens
Prior art date
Application number
AT07011493T
Other languages
English (en)
Inventor
Harald Kropshofer
Anne Vogt
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Application granted granted Critical
Publication of ATE474851T1 publication Critical patent/ATE474851T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/70539—MHC-molecules, e.g. HLA-molecules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/08—Drugs for disorders of the urinary system of the prostate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/04—Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Oncology (AREA)
  • Toxicology (AREA)
  • Genetics & Genomics (AREA)
  • Virology (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Communicable Diseases (AREA)
  • Diabetes (AREA)
  • Cell Biology (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Neurology (AREA)
  • AIDS & HIV (AREA)
  • Pain & Pain Management (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Neurosurgery (AREA)
  • Transplantation (AREA)
  • Biomedical Technology (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
AT07011493T 2002-10-02 2003-09-24 Verfahren zur identifizierung antigener peptide ATE474851T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP02022223 2002-10-02

Publications (1)

Publication Number Publication Date
ATE474851T1 true ATE474851T1 (de) 2010-08-15

Family

ID=32116218

Family Applications (2)

Application Number Title Priority Date Filing Date
AT03021521T ATE391723T1 (de) 2002-10-02 2003-09-24 Verfahren zur identifizierung antigener peptide
AT07011493T ATE474851T1 (de) 2002-10-02 2003-09-24 Verfahren zur identifizierung antigener peptide

Family Applications Before (1)

Application Number Title Priority Date Filing Date
AT03021521T ATE391723T1 (de) 2002-10-02 2003-09-24 Verfahren zur identifizierung antigener peptide

Country Status (8)

Country Link
US (1) US20040086521A1 (de)
EP (3) EP1405862B1 (de)
JP (3) JP4620339B2 (de)
AT (2) ATE391723T1 (de)
AU (1) AU2003248438A1 (de)
CA (1) CA2441690C (de)
DE (2) DE60333500D1 (de)
ES (1) ES2346574T3 (de)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2359974C2 (ru) * 2003-08-07 2009-06-27 Ф.Хоффманн-Ля Рош Аг Ra антигенные пептиды
DE602006010934D1 (de) * 2005-04-20 2010-01-21 Hoffmann La Roche Verfahren zur Identifizierung von Epitopen in Zusammenhang mit Immunogenität bei Biopharmazeutika
EP1715343B1 (de) 2005-04-20 2009-12-09 F. Hoffmann-La Roche Ag Verfahren zur Identifizierung von Epitopen in Zusammenhang mit Immunogenität bei Biopharmazeutika
WO2007055283A1 (ja) * 2005-11-10 2007-05-18 Jsr Corporation 核内受容体タンパク質複合体のプロテオミクス解析方法
US20100086938A1 (en) * 2006-11-29 2010-04-08 Takashi Shimada Mass spectrometry of biological sample using immunoprecipitation
KR20200091961A (ko) * 2008-01-18 2020-07-31 프레지던트 앤드 펠로우즈 오브 하바드 칼리지 체액 내에서 질병 또는 병태의 시그너쳐의 검출 방법
KR20120030442A (ko) * 2009-05-29 2012-03-28 노파르티스 아게 인플루엔자 바이러스 혈구응집소에 대한 분석
AU2011280997A1 (en) 2010-07-23 2013-02-28 President And Fellows Of Harvard College Methods of detecting autoimmune or immune-related diseases or conditions
WO2012012717A1 (en) 2010-07-23 2012-01-26 President And Fellows Of Harvard College Methods of detecting prenatal or pregnancy-related diseases or conditions
WO2013150680A1 (ja) * 2012-04-06 2013-10-10 独立行政法人産業技術総合研究所 プロテインタグ、タグ化タンパク質及びタンパク質精製方法
WO2014164366A1 (en) 2013-03-09 2014-10-09 Harry Stylli Methods of detecting cancer
EP3152574A4 (de) * 2014-06-06 2017-12-06 Singapore Health Services Pte Ltd Verfahren zur verwendung von zellen in zusammenhang mit einer autoimmunkrankheit
KR101831483B1 (ko) 2014-06-17 2018-02-23 이화여자대학교 산학협력단 Mhc-페리틴 결합체, 이를 포함하는 나노파티클 및 이의 용도
TWI719939B (zh) 2014-07-14 2021-03-01 日商中外製藥股份有限公司 鑑定蛋白質抗原決定位之方法
WO2016079143A1 (de) 2014-11-17 2016-05-26 Pharis Biotec Gmbh Inhibitor der viralen hepatitis c infektion
CN105928771B (zh) * 2016-04-08 2019-01-18 西藏恒久投资有限公司 一种检测疫苗抗原含量的样品前处理方法
CN110118845A (zh) * 2018-02-06 2019-08-13 北京金则医学科技发展有限公司 检测多种氨基酸和酰基肉碱、甲基丙二酸的方法和试剂盒
JP6712369B2 (ja) * 2018-05-29 2020-06-24 株式会社森永生科学研究所 抗ペプチド抗体の製造方法及び設計方法
JP7145980B2 (ja) * 2018-06-15 2022-10-03 エフ．ホフマン－ラ ロシュ アーゲー 腫瘍浸潤リンパ球にて発現するｔ細胞受容体により認識される抗原を識別するためのシステム
CA3108716A1 (en) * 2018-08-14 2020-02-20 Board Of Regents, The University Of Texas Systems Single molecule sequencing peptides bound to the major histocompatibility complex
EA202190693A1 (ru) * 2018-09-11 2021-07-27 Джуно Терапьютикс, Инк. Способы анализа масс-спектрометрии композиций модифицированных клеток
JP2021047198A (ja) * 2020-12-04 2021-03-25 Ｋａｒｙｄｏ ＴｈｅｒａｐｅｕｔｉＸ株式会社 心筋梗塞、認知症、および腫瘍からなる群から選択される一種を予防、または治療するための有効成分の候補物質のスクリーニング装置、スクリーニングプログラム、およびスクリーニング方法
CN113406240B (zh) * 2021-07-02 2023-03-24 杭州艾儿默细胞生物科技有限公司 检测pHLA复合物中抗原肽的超滤-高效液相色谱法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6017540A (en) * 1997-02-07 2000-01-25 Fordham University Prevention and treatment of primary and metastatic neoplastic diseases and infectious diseases with heat shock/stress protein-peptide complexes
WO2000005250A1 (en) * 1998-07-23 2000-02-03 Yeda Research And Development Co., Ltd Treatment of autoimmune conditions with copolymer 1 and related copolymers and peptides
WO2000005249A2 (en) * 1998-07-23 2000-02-03 The President And Fellows Of Harvard College Synthetic peptides and methods of use for autoimmune disease therapies
WO2002040647A1 (en) * 2000-11-14 2002-05-23 U.S. Army Medical Research Institute Of Infectious Diseases Method of establishing cultures of human dendritic cells and use thereof

Also Published As

Publication number Publication date
EP1405862A2 (de) 2004-04-07
DE60333500D1 (de) 2010-09-02
EP1714981A3 (de) 2006-12-20
AU2003248438A1 (en) 2004-04-22
ES2346574T3 (es) 2010-10-18
JP4620339B2 (ja) 2011-01-26
EP1826217B1 (de) 2010-07-21
JP2004123749A (ja) 2004-04-22
CA2441690C (en) 2011-08-02
JP2011012073A (ja) 2011-01-20
ATE391723T1 (de) 2008-04-15
US20040086521A1 (en) 2004-05-06
EP1714981A2 (de) 2006-10-25
EP1405862A3 (de) 2004-06-09
EP1405862B1 (de) 2008-04-09
EP1826217A1 (de) 2007-08-29
CA2441690A1 (en) 2004-04-02
DE60320196D1 (de) 2008-05-21
DE60320196T2 (de) 2009-05-14
JP2007211020A (ja) 2007-08-23

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