ATE465171T1 - Neue chemokine bindende peptide, die die biologische aktivität dieser chemokine modulieren - Google Patents
Neue chemokine bindende peptide, die die biologische aktivität dieser chemokine modulierenInfo
- Publication number
- ATE465171T1 ATE465171T1 AT03743008T AT03743008T ATE465171T1 AT E465171 T1 ATE465171 T1 AT E465171T1 AT 03743008 T AT03743008 T AT 03743008T AT 03743008 T AT03743008 T AT 03743008T AT E465171 T1 ATE465171 T1 AT E465171T1
- Authority
- AT
- Austria
- Prior art keywords
- modulate
- chemokines
- peptides
- chemokine
- biological activity
- Prior art date
Links
- 102000019034 Chemokines Human genes 0.000 title abstract 5
- 108010012236 Chemokines Proteins 0.000 title abstract 5
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 4
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 4
- 230000004071 biological effect Effects 0.000 title abstract 2
- 239000003446 ligand Substances 0.000 abstract 2
- 102000009410 Chemokine receptor Human genes 0.000 abstract 1
- 108050000299 Chemokine receptor Proteins 0.000 abstract 1
- 108091035707 Consensus sequence Proteins 0.000 abstract 1
- 239000000556 agonist Substances 0.000 abstract 1
- 239000005557 antagonist Substances 0.000 abstract 1
- 230000009141 biological interaction Effects 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 239000000816 peptidomimetic Substances 0.000 abstract 1
- 150000003384 small molecules Chemical class 0.000 abstract 1
- 229940124597 therapeutic agent Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/10—Peptides having 12 to 20 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65G—TRANSPORT OR STORAGE DEVICES, e.g. CONVEYORS FOR LOADING OR TIPPING, SHOP CONVEYOR SYSTEMS OR PNEUMATIC TUBE CONVEYORS
- B65G11/00—Chutes
- B65G11/02—Chutes of straight form
- B65G11/023—Chutes of straight form for articles
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65G—TRANSPORT OR STORAGE DEVICES, e.g. CONVEYORS FOR LOADING OR TIPPING, SHOP CONVEYOR SYSTEMS OR PNEUMATIC TUBE CONVEYORS
- B65G11/00—Chutes
- B65G11/16—Interior surfaces; Linings
- B65G11/163—Interior surfaces; Linings for articles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/64—Cyclic peptides containing only normal peptide links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Epidemiology (AREA)
- Diabetes (AREA)
- Oncology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Rheumatology (AREA)
- Communicable Diseases (AREA)
- Dermatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Virology (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Pain & Pain Management (AREA)
- Physical Education & Sports Medicine (AREA)
- Pulmonology (AREA)
- Obesity (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US35999502P | 2002-02-28 | 2002-02-28 | |
PCT/IL2003/000155 WO2003072599A2 (en) | 2002-02-28 | 2003-02-27 | Novel chemokine binding peptides capable of modulating the biological activity of chemokines |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE465171T1 true ATE465171T1 (de) | 2010-05-15 |
Family
ID=27766173
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT03743008T ATE465171T1 (de) | 2002-02-28 | 2003-02-27 | Neue chemokine bindende peptide, die die biologische aktivität dieser chemokine modulieren |
Country Status (6)
Country | Link |
---|---|
US (5) | US20030221931A1 (de) |
EP (2) | EP1519945B1 (de) |
AT (1) | ATE465171T1 (de) |
AU (1) | AU2003209636A1 (de) |
DE (1) | DE60332239D1 (de) |
WO (1) | WO2003072599A2 (de) |
Families Citing this family (28)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20030221931A1 (en) | 2002-02-28 | 2003-12-04 | Steve Marsh | Sliding device |
WO2005039616A1 (en) * | 2003-10-29 | 2005-05-06 | Ramot At Tel Aviv University Ltd. | Angiogenic peptides and uses thereof |
WO2005048823A2 (en) * | 2003-11-17 | 2005-06-02 | Janssen Pharmaceutica N.V. | Modeling of systemic inflammatory response to infection |
CN101031792A (zh) * | 2004-08-05 | 2007-09-05 | L-3通信安全与检测***有限公司 | 通过量增加的检查站 |
US7871978B2 (en) * | 2004-11-04 | 2011-01-18 | University Of Virginia Patent Foundation | Bone tropic peptides |
DE102006006208B4 (de) * | 2006-02-09 | 2010-11-11 | Smiths Heimann Gmbh | Kontrollstation zur Überprüfung von Handgepäck und anderen von Personen mitgeführten Gegenständen |
US10745701B2 (en) | 2007-06-28 | 2020-08-18 | The Trustees Of Princeton University | Methods of identifying and treating poor-prognosis cancers |
US20090324596A1 (en) | 2008-06-30 | 2009-12-31 | The Trustees Of Princeton University | Methods of identifying and treating poor-prognosis cancers |
US9516460B2 (en) | 2008-03-28 | 2016-12-06 | Securitypoint Holdings Llc | Systems and methods for security checkpoint condition information and sharing |
US9116513B2 (en) | 2008-03-28 | 2015-08-25 | Securitypoint Holdings, Inc. | Methods and systems for efficient security screening |
WO2010053763A1 (en) * | 2008-10-29 | 2010-05-14 | Academia Sinica | Tumor-targeting peptides and uses thereof |
US9427456B2 (en) | 2009-06-14 | 2016-08-30 | Biokine Therapeutics Ltd. | Peptide therapy for increasing platelet levels |
EP2443137B1 (de) | 2009-06-15 | 2015-05-20 | Biokine Therapeutics Ltd. | Neue chemokin-bindende peptide, die die fähigkeit, den fortschritt von autoimmunität, entzündung und krebs aufweisen |
EP2385057A1 (de) * | 2010-05-05 | 2011-11-09 | Centre National de la Recherche Scientifique | Peptidderivate zur Biofunktionalisierung von Siliciumsubstraten und deren Anwendungen |
CN102174080B (zh) * | 2010-09-19 | 2014-07-09 | 复旦大学 | 具有脑靶向递药特性的多肽及其制备方法 |
CN103328496A (zh) | 2010-10-25 | 2013-09-25 | 中央研究院 | 癌靶向肽及其于癌症治疗与诊断的应用 |
BR112013029482A2 (pt) | 2011-05-16 | 2016-08-09 | Genzyme Corp | utilização de antagonistas cxr4 |
WO2013160895A1 (en) | 2012-04-24 | 2013-10-31 | Biokine Therapeutics Ltd. | Peptides and use thereof in the treatment of large cell lung cancer |
FR3022142B1 (fr) | 2014-06-16 | 2019-07-12 | Universite Paul Sabatier - Toulouse Iii | Inhibition de la chimiokine ccl7 ou de son recepteur ccr3 pour le traitement et le diagnostic du cancer de la prostate |
WO2017009843A2 (en) | 2015-07-16 | 2017-01-19 | Biokine Therapeutics Ltd. | Compositions, articles of manufacture and methods for treating cancer |
WO2017103932A1 (en) | 2015-12-17 | 2017-06-22 | Biokine Therapeutics Ltd. | Small molecules for inhibiting chemokine activity, a kinase activity and/or cancer cells growth |
WO2017103931A1 (en) | 2015-12-17 | 2017-06-22 | Biokine Therapeutics Ltd. | Small molecules against cancer |
BR112018016924A2 (pt) | 2016-02-23 | 2019-01-02 | Biokine Therapeutics Ltd | método de seleção de regime de tratamento para indivíduo que tem leucemia mieloide aguda (lma), método de maximização de resposta ao tratamento de leucemia mieloide aguda (lma), método de tratamento de lma, antagonista de cxcr4 e agente quimioterápico no tratamento de lma |
EP3509619B1 (de) * | 2016-09-07 | 2024-06-26 | Kyoto University | Peptide und peptidkonjugate zur behandlung von psychischen erkrankungen |
BR112021006752A2 (pt) | 2018-10-12 | 2021-07-13 | Theradaptive, Inc. | polipeptídeos incluindo uma sequência de ligação de betafosfato tricálcico e usos dos mesmos |
BR112021022775A2 (pt) | 2019-05-15 | 2022-02-01 | Alonbio Ltd | Moléculas pequenas para tratamento do câncer, inibição da atividade da quimiocina e/ou indução da morte celular |
US20230203115A1 (en) * | 2020-03-06 | 2023-06-29 | Theradaptive, Inc. | Therapeutic compositions comprising graft materials and beta-tcp binding peptides and uses thereof |
GB202209520D0 (en) | 2022-06-29 | 2022-08-10 | Univ Oxford Innovation Ltd | Peptides |
Family Cites Families (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US250025A (en) * | 1881-11-22 | Joseph | ||
US318320A (en) * | 1885-05-19 | Ajstsel steickland | ||
US39211A (en) * | 1863-07-14 | Improved skid for discharging and loading vessels | ||
US192164A (en) * | 1877-06-19 | Improvement in bathing apparatus | ||
US271A (en) * | 1837-07-17 | George wilbur | ||
US243451A (en) * | 1881-06-28 | Automatic cash-carrier | ||
US1252616A (en) * | 1917-03-02 | 1918-01-08 | Ellen W Reif | Toy. |
US1789885A (en) * | 1929-03-09 | 1931-01-20 | Skinner Thomas | Coal chute |
US2218444A (en) * | 1938-04-11 | 1940-10-15 | George S Vineyard | Merchandise dispenser |
US2742288A (en) * | 1953-06-04 | 1956-04-17 | Jacques A Brunel | Chute for sking and tobogganing |
US3064784A (en) * | 1960-08-01 | 1962-11-20 | Admos Inc | Supporting structures for chutes |
US4418813A (en) * | 1981-05-20 | 1983-12-06 | Modular Automation, Inc. | Modular open chuting |
US5928939A (en) * | 1995-03-01 | 1999-07-27 | Ludwig Institute For Cancer Research | Vascular endothelial growth factor-b and dna coding therefor |
US6196370B1 (en) * | 1998-03-27 | 2001-03-06 | Tonoga Limited | Package conveying surface with liner |
JP3821587B2 (ja) * | 1998-08-31 | 2006-09-13 | ユニ・チャーム株式会社 | ウェットティッシュの積層体及びこれが収納された製品 |
WO2002061087A2 (en) * | 2000-12-19 | 2002-08-08 | Lifespan Biosciences, Inc. | Antigenic peptides, such as for g protein-coupled receptors (gpcrs), antibodies thereto, and systems for identifying such antigenic peptides |
US20030027751A1 (en) * | 2001-04-10 | 2003-02-06 | Genvec, Inc. | VEGF fusion proteins |
AU2002363253A1 (en) * | 2001-11-01 | 2003-05-12 | Gpc Biotech Inc. | Endothelial-cell binding peptides for diagnosis and therapy |
US20030221931A1 (en) | 2002-02-28 | 2003-12-04 | Steve Marsh | Sliding device |
-
2003
- 2003-02-18 US US10/369,410 patent/US20030221931A1/en not_active Abandoned
- 2003-02-27 EP EP03743008A patent/EP1519945B1/de not_active Expired - Lifetime
- 2003-02-27 AT AT03743008T patent/ATE465171T1/de not_active IP Right Cessation
- 2003-02-27 AU AU2003209636A patent/AU2003209636A1/en not_active Abandoned
- 2003-02-27 EP EP10153629A patent/EP2287175A3/de not_active Withdrawn
- 2003-02-27 DE DE60332239T patent/DE60332239D1/de not_active Expired - Lifetime
- 2003-02-27 WO PCT/IL2003/000155 patent/WO2003072599A2/en not_active Application Discontinuation
- 2003-08-28 US US10/649,873 patent/US7488717B2/en not_active Expired - Fee Related
-
2009
- 2009-01-22 US US12/320,281 patent/US8039440B2/en not_active Expired - Fee Related
-
2011
- 2011-10-17 US US13/274,478 patent/US8383769B2/en not_active Expired - Fee Related
-
2013
- 2013-01-28 US US13/751,183 patent/US8796227B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
US20040171552A1 (en) | 2004-09-02 |
US20120028913A1 (en) | 2012-02-02 |
EP1519945A2 (de) | 2005-04-06 |
US20030221931A1 (en) | 2003-12-04 |
US8796227B2 (en) | 2014-08-05 |
EP2287175A2 (de) | 2011-02-23 |
US7488717B2 (en) | 2009-02-10 |
AU2003209636A8 (en) | 2003-09-09 |
WO2003072599A3 (en) | 2003-12-18 |
US20100173848A1 (en) | 2010-07-08 |
WO2003072599A2 (en) | 2003-09-04 |
EP2287175A3 (de) | 2012-05-16 |
DE60332239D1 (de) | 2010-06-02 |
AU2003209636A1 (en) | 2003-09-09 |
US20130130996A1 (en) | 2013-05-23 |
EP1519945B1 (de) | 2010-04-21 |
US8383769B2 (en) | 2013-02-26 |
US8039440B2 (en) | 2011-10-18 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |