ATE465171T1 - Neue chemokine bindende peptide, die die biologische aktivität dieser chemokine modulieren - Google Patents

Neue chemokine bindende peptide, die die biologische aktivität dieser chemokine modulieren

Info

Publication number
ATE465171T1
ATE465171T1 AT03743008T AT03743008T ATE465171T1 AT E465171 T1 ATE465171 T1 AT E465171T1 AT 03743008 T AT03743008 T AT 03743008T AT 03743008 T AT03743008 T AT 03743008T AT E465171 T1 ATE465171 T1 AT E465171T1
Authority
AT
Austria
Prior art keywords
modulate
chemokines
peptides
chemokine
biological activity
Prior art date
Application number
AT03743008T
Other languages
English (en)
Inventor
Amnon Peled
Orly Eizenberg
Dalit Vaizel-Ohayon
Original Assignee
Biokine Therapeutics Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biokine Therapeutics Ltd filed Critical Biokine Therapeutics Ltd
Application granted granted Critical
Publication of ATE465171T1 publication Critical patent/ATE465171T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08—Peptides having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/10—Peptides having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65G—TRANSPORT OR STORAGE DEVICES, e.g. CONVEYORS FOR LOADING OR TIPPING, SHOP CONVEYOR SYSTEMS OR PNEUMATIC TUBE CONVEYORS
    • B65G11/00—Chutes
    • B65G11/02—Chutes of straight form
    • B65G11/023—Chutes of straight form for articles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65G—TRANSPORT OR STORAGE DEVICES, e.g. CONVEYORS FOR LOADING OR TIPPING, SHOP CONVEYOR SYSTEMS OR PNEUMATIC TUBE CONVEYORS
    • B65G11/00—Chutes
    • B65G11/16—Interior surfaces; Linings
    • B65G11/163—Interior surfaces; Linings for articles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/64—Cyclic peptides containing only normal peptide links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Oncology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Rheumatology (AREA)
  • Communicable Diseases (AREA)
  • Dermatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Virology (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Pain & Pain Management (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pulmonology (AREA)
  • Obesity (AREA)
AT03743008T 2002-02-28 2003-02-27 Neue chemokine bindende peptide, die die biologische aktivität dieser chemokine modulieren ATE465171T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US35999502P 2002-02-28 2002-02-28
PCT/IL2003/000155 WO2003072599A2 (en) 2002-02-28 2003-02-27 Novel chemokine binding peptides capable of modulating the biological activity of chemokines

Publications (1)

Publication Number Publication Date
ATE465171T1 true ATE465171T1 (de) 2010-05-15

Family

ID=27766173

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03743008T ATE465171T1 (de) 2002-02-28 2003-02-27 Neue chemokine bindende peptide, die die biologische aktivität dieser chemokine modulieren

Country Status (6)

Country Link
US (5) US20030221931A1 (de)
EP (2) EP1519945B1 (de)
AT (1) ATE465171T1 (de)
AU (1) AU2003209636A1 (de)
DE (1) DE60332239D1 (de)
WO (1) WO2003072599A2 (de)

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US20030221931A1 (en) 2002-02-28 2003-12-04 Steve Marsh Sliding device
WO2005039616A1 (en) * 2003-10-29 2005-05-06 Ramot At Tel Aviv University Ltd. Angiogenic peptides and uses thereof
WO2005048823A2 (en) * 2003-11-17 2005-06-02 Janssen Pharmaceutica N.V. Modeling of systemic inflammatory response to infection
CN101031792A (zh) * 2004-08-05 2007-09-05 L－3通信安全与检测***有限公司 通过量增加的检查站
US7871978B2 (en) * 2004-11-04 2011-01-18 University Of Virginia Patent Foundation Bone tropic peptides
DE102006006208B4 (de) * 2006-02-09 2010-11-11 Smiths Heimann Gmbh Kontrollstation zur Überprüfung von Handgepäck und anderen von Personen mitgeführten Gegenständen
US10745701B2 (en) 2007-06-28 2020-08-18 The Trustees Of Princeton University Methods of identifying and treating poor-prognosis cancers
US20090324596A1 (en) 2008-06-30 2009-12-31 The Trustees Of Princeton University Methods of identifying and treating poor-prognosis cancers
US9516460B2 (en) 2008-03-28 2016-12-06 Securitypoint Holdings Llc Systems and methods for security checkpoint condition information and sharing
US9116513B2 (en) 2008-03-28 2015-08-25 Securitypoint Holdings, Inc. Methods and systems for efficient security screening
WO2010053763A1 (en) * 2008-10-29 2010-05-14 Academia Sinica Tumor-targeting peptides and uses thereof
US9427456B2 (en) 2009-06-14 2016-08-30 Biokine Therapeutics Ltd. Peptide therapy for increasing platelet levels
EP2443137B1 (de) 2009-06-15 2015-05-20 Biokine Therapeutics Ltd. Neue chemokin-bindende peptide, die die fähigkeit, den fortschritt von autoimmunität, entzündung und krebs aufweisen
EP2385057A1 (de) * 2010-05-05 2011-11-09 Centre National de la Recherche Scientifique Peptidderivate zur Biofunktionalisierung von Siliciumsubstraten und deren Anwendungen
CN102174080B (zh) * 2010-09-19 2014-07-09 复旦大学 具有脑靶向递药特性的多肽及其制备方法
CN103328496A (zh) 2010-10-25 2013-09-25 中央研究院 癌靶向肽及其于癌症治疗与诊断的应用
BR112013029482A2 (pt) 2011-05-16 2016-08-09 Genzyme Corp utilização de antagonistas cxr4
WO2013160895A1 (en) 2012-04-24 2013-10-31 Biokine Therapeutics Ltd. Peptides and use thereof in the treatment of large cell lung cancer
FR3022142B1 (fr) 2014-06-16 2019-07-12 Universite Paul Sabatier - Toulouse Iii Inhibition de la chimiokine ccl7 ou de son recepteur ccr3 pour le traitement et le diagnostic du cancer de la prostate
WO2017009843A2 (en) 2015-07-16 2017-01-19 Biokine Therapeutics Ltd. Compositions, articles of manufacture and methods for treating cancer
WO2017103932A1 (en) 2015-12-17 2017-06-22 Biokine Therapeutics Ltd. Small molecules for inhibiting chemokine activity, a kinase activity and/or cancer cells growth
WO2017103931A1 (en) 2015-12-17 2017-06-22 Biokine Therapeutics Ltd. Small molecules against cancer
BR112018016924A2 (pt) 2016-02-23 2019-01-02 Biokine Therapeutics Ltd método de seleção de regime de tratamento para indivíduo que tem leucemia mieloide aguda (lma), método de maximização de resposta ao tratamento de leucemia mieloide aguda (lma), método de tratamento de lma, antagonista de cxcr4 e agente quimioterápico no tratamento de lma
EP3509619B1 (de) * 2016-09-07 2024-06-26 Kyoto University Peptide und peptidkonjugate zur behandlung von psychischen erkrankungen
BR112021006752A2 (pt) 2018-10-12 2021-07-13 Theradaptive, Inc. polipeptídeos incluindo uma sequência de ligação de betafosfato tricálcico e usos dos mesmos
BR112021022775A2 (pt) 2019-05-15 2022-02-01 Alonbio Ltd Moléculas pequenas para tratamento do câncer, inibição da atividade da quimiocina e/ou indução da morte celular
US20230203115A1 (en) * 2020-03-06 2023-06-29 Theradaptive, Inc. Therapeutic compositions comprising graft materials and beta-tcp binding peptides and uses thereof
GB202209520D0 (en) 2022-06-29 2022-08-10 Univ Oxford Innovation Ltd Peptides

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Also Published As

Publication number Publication date
US20040171552A1 (en) 2004-09-02
US20120028913A1 (en) 2012-02-02
EP1519945A2 (de) 2005-04-06
US20030221931A1 (en) 2003-12-04
US8796227B2 (en) 2014-08-05
EP2287175A2 (de) 2011-02-23
US7488717B2 (en) 2009-02-10
AU2003209636A8 (en) 2003-09-09
WO2003072599A3 (en) 2003-12-18
US20100173848A1 (en) 2010-07-08
WO2003072599A2 (en) 2003-09-04
EP2287175A3 (de) 2012-05-16
DE60332239D1 (de) 2010-06-02
AU2003209636A1 (en) 2003-09-09
US20130130996A1 (en) 2013-05-23
EP1519945B1 (de) 2010-04-21
US8383769B2 (en) 2013-02-26
US8039440B2 (en) 2011-10-18

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